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The map label for this gene is ubiG [H]

Identifier: 146343398

GI number: 146343398

Start: 6877225

End: 6878007

Strand: Direct

Name: ubiG [H]

Synonym: BRADO6627

Alternate gene names: 146343398

Gene position: 6877225-6878007 (Clockwise)

Preceding gene: 146343397

Following gene: 146343402

Centisome position: 92.23

GC content: 70.11

Gene sequence:

>783_bases
ATGCTCTACAAGGATGCCGTGAAGCCCGCTTTCGCCGCGACCGCCGAGGGCCCCTCCACCATCGATCCCGCCGAGATCGC
GCGGTTCTCGCGTCTGGCCGAGGAATGGTGGAAGCCGGACGGCGCGTTCAAGCTGGTGCACGCCTTCAACGCCGCGCGCG
TGCGCTACCTCTGCGATCGCCTGCCCGCGCTGGTCGGCCGCGACGCCGGAGCGAACCTGCCGCTGGCCGGCCTCGACATC
ATCGACGTCGGCTGCGGCGCCGGCATCGTCACCGAGCCGTTGTCGCGGCTCGGTGCCGAGACCCTGGGCATCGATGCCGC
CGAGCGCAACGTGCTGGTCGCCGCCGACCACGCTCGCAGGCAGGGCGCGCTCGTTTCCTACCGCCACGCGCTGCCGGAGG
ATCTCGCCGCCGAAGGCGAGCAGGCCGACATCGTGCTGACGCTCGAAGTGGTCGAGCACGTCGCCGATCTCGCCCGCTTC
GTCGGCCATGTCGCCGACCTCGTGCGTCCCGGCGGCCTGCTCGTGATCGGCACCTTGAACCGCACGCCGATCTCGTTCGT
GAAGGCGATCATCGGCGCCGAATACATCCTCGGCTGGCTGCCGCGCGGCACGCATGACTGGCGCCGGTTCGTGAAGCCTT
CGGAGCTGCGGACGCTGCTCGCGCCGCGTCGCTTCATTCCGGTGGAGACGGTGGCCGTCGAGTTGAACCCGCTGACGATG
CGCTGGCGCATCGGCGGCCGCCCCTCGACCAACTACCTGCAGATCTACCGCCGCATGCCGTGA

Upstream 100 bases:

>100_bases
CATGGCGCCTCGGTCGTGCTCACCCTGATCCATATCGTGCTGAGCGCCGCCGTGCTGCTGCGCCTCGCGCAGTAGCGCCG
TCGGCGGAGAAAGGACGACG

Downstream 100 bases:

>100_bases
GGGCGCGCGCTGCTTGCGAAGCCCGGCAGTCGCGTCACGACGGCTCCGGGACATCCTCCCTGGCACCGGCATGCTGCTCG
GCCGGCGCCAGGAAGCTGGC

Product: bifunctional 3-demethylubiquinone-9 3-methyltransferase/2-octaprenyl-6-hydroxy phenol methylase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MLYKDAVKPAFAATAEGPSTIDPAEIARFSRLAEEWWKPDGAFKLVHAFNAARVRYLCDRLPALVGRDAGANLPLAGLDI
IDVGCGAGIVTEPLSRLGAETLGIDAAERNVLVAADHARRQGALVSYRHALPEDLAAEGEQADIVLTLEVVEHVADLARF
VGHVADLVRPGGLLVIGTLNRTPISFVKAIIGAEYILGWLPRGTHDWRRFVKPSELRTLLAPRRFIPVETVAVELNPLTM
RWRIGGRPSTNYLQIYRRMP

Sequences:

>Translated_260_residues
MLYKDAVKPAFAATAEGPSTIDPAEIARFSRLAEEWWKPDGAFKLVHAFNAARVRYLCDRLPALVGRDAGANLPLAGLDI
IDVGCGAGIVTEPLSRLGAETLGIDAAERNVLVAADHARRQGALVSYRHALPEDLAAEGEQADIVLTLEVVEHVADLARF
VGHVADLVRPGGLLVIGTLNRTPISFVKAIIGAEYILGWLPRGTHDWRRFVKPSELRTLLAPRRFIPVETVAVELNPLTM
RWRIGGRPSTNYLQIYRRMP
>Mature_260_residues
MLYKDAVKPAFAATAEGPSTIDPAEIARFSRLAEEWWKPDGAFKLVHAFNAARVRYLCDRLPALVGRDAGANLPLAGLDI
IDVGCGAGIVTEPLSRLGAETLGIDAAERNVLVAADHARRQGALVSYRHALPEDLAAEGEQADIVLTLEVVEHVADLARF
VGHVADLVRPGGLLVIGTLNRTPISFVKAIIGAEYILGWLPRGTHDWRRFVKPSELRTLLAPRRFIPVETVAVELNPLTM
RWRIGGRPSTNYLQIYRRMP

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family [H]

Homologues:

Organism=Homo sapiens, GI118600965, Length=238, Percent_Identity=35.7142857142857, Blast_Score=160, Evalue=1e-39,
Organism=Escherichia coli, GI1788564, Length=235, Percent_Identity=35.3191489361702, Blast_Score=153, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI115533050, Length=242, Percent_Identity=31.8181818181818, Blast_Score=116, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6324476, Length=229, Percent_Identity=27.0742358078603, Blast_Score=99, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24585589, Length=227, Percent_Identity=31.2775330396476, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI281365311, Length=220, Percent_Identity=31.3636363636364, Blast_Score=115, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR010233 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.64 [H]

Molecular weight: Translated: 28494; Mature: 28494

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYKDAVKPAFAATAEGPSTIDPAEIARFSRLAEEWWKPDGAFKLVHAFNAARVRYLCDR
CCCHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
LPALVGRDAGANLPLAGLDIIDVGCGAGIVTEPLSRLGAETLGIDAAERNVLVAADHARR
HHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCHHHHCCCHHHCCEEEEECCHHH
QGALVSYRHALPEDLAAEGEQADIVLTLEVVEHVADLARFVGHVADLVRPGGLLVIGTLN
CCCHHHHHHHCCHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
RTPISFVKAIIGAEYILGWLPRGTHDWRRFVKPSELRTLLAPRRFIPVETVAVELNPLTM
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHCCCCCCCEEEEEEEECCEEE
RWRIGGRPSTNYLQIYRRMP
EEEECCCCCCHHHHHEECCC
>Mature Secondary Structure
MLYKDAVKPAFAATAEGPSTIDPAEIARFSRLAEEWWKPDGAFKLVHAFNAARVRYLCDR
CCCHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
LPALVGRDAGANLPLAGLDIIDVGCGAGIVTEPLSRLGAETLGIDAAERNVLVAADHARR
HHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCHHHHCCCHHHCCEEEEECCHHH
QGALVSYRHALPEDLAAEGEQADIVLTLEVVEHVADLARFVGHVADLVRPGGLLVIGTLN
CCCHHHHHHHCCHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
RTPISFVKAIIGAEYILGWLPRGTHDWRRFVKPSELRTLLAPRRFIPVETVAVELNPLTM
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHCCCCCCCEEEEEEEECCEEE
RWRIGGRPSTNYLQIYRRMP
EEEECCCCCCHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA