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The map label for this gene is 146343358

Identifier: 146343358

GI number: 146343358

Start: 6835843

End: 6836280

Strand: Direct

Name: 146343358

Synonym: BRADO6585

Alternate gene names: NA

Gene position: 6835843-6836280 (Clockwise)

Preceding gene: 146343357

Following gene: 146343362

Centisome position: 91.68

GC content: 65.07

Gene sequence:

>438_bases
ATGACCGGCGAAGGCCCGCAGGTCAAAACCACCGACGACATCTTCAAGGGCAAGAAGGTCGCGCTGTTCGCGGTCCCCGG
CGCCTACACCGGCACCTGCCACAAGATGCATCTGCCCAGCATCTTCCTCAACGCCTATGCGCTGAAGGACAAGGGCGTCG
ACACCATCGCGATCGTCTCGGTCAACGACGCCTTCGTGATGAATGCCTGGAAGCGCGACACCGACCAGCGCGACGAGGCG
GTGTTCCTGGCCGACGGCAATGCGGAGTTCACCAAGGCCATCGGCATGGAGCTCGACGCCTCCGGCGCCGGGCTGGGCAT
CCGCTCCAAGCGCTACTCGATGCTGGTCGAGGACGGCAAGGTGACCAAGCTGAACCTCGAAGCCGCCCCGGGCAAGGTCG
AAGTCTCCGGCGGCGACACGCTGCTGGGGCAGCTGTGA

Upstream 100 bases:

>100_bases
CATAGTGTAGCGCGCCAAGCGCAAACGATATCCAGGGGAAGGAGTTATTCCAATGACTATTCAGGTAGGCGATCAGCTGC
CGCAGGCTCAGTTCCGCGTC

Downstream 100 bases:

>100_bases
GCTGATCGATCTATCGAGCTTGAGGCACACGGCCTCCCCACCATCGGTGTCATTCCCTGCGAAAGCGGGGAATCGAGTAC
GCCGCGGCCTCTCGGTTGAA

Product: putative peroxiredoxin

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 145; Mature: 144

Protein sequence:

>145_residues
MTGEGPQVKTTDDIFKGKKVALFAVPGAYTGTCHKMHLPSIFLNAYALKDKGVDTIAIVSVNDAFVMNAWKRDTDQRDEA
VFLADGNAEFTKAIGMELDASGAGLGIRSKRYSMLVEDGKVTKLNLEAAPGKVEVSGGDTLLGQL

Sequences:

>Translated_145_residues
MTGEGPQVKTTDDIFKGKKVALFAVPGAYTGTCHKMHLPSIFLNAYALKDKGVDTIAIVSVNDAFVMNAWKRDTDQRDEA
VFLADGNAEFTKAIGMELDASGAGLGIRSKRYSMLVEDGKVTKLNLEAAPGKVEVSGGDTLLGQL
>Mature_144_residues
TGEGPQVKTTDDIFKGKKVALFAVPGAYTGTCHKMHLPSIFLNAYALKDKGVDTIAIVSVNDAFVMNAWKRDTDQRDEAV
FLADGNAEFTKAIGMELDASGAGLGIRSKRYSMLVEDGKVTKLNLEAAPGKVEVSGGDTLLGQL

Specific function: Unknown

COG id: COG0678

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI6912238, Length=135, Percent_Identity=42.2222222222222, Blast_Score=97, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6323138, Length=146, Percent_Identity=35.6164383561644, Blast_Score=71, Evalue=5e-14,
Organism=Drosophila melanogaster, GI78706776, Length=118, Percent_Identity=50.8474576271186, Blast_Score=111, Evalue=1e-25,
Organism=Drosophila melanogaster, GI78709078, Length=118, Percent_Identity=50.8474576271186, Blast_Score=111, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR011906
- InterPro:   IPR014025
- InterPro:   IPR013740
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin; PF08534 Redoxin [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 15453; Mature: 15322

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGEGPQVKTTDDIFKGKKVALFAVPGAYTGTCHKMHLPSIFLNAYALKDKGVDTIAIVS
CCCCCCCEECCHHHHCCCEEEEEECCCCCCCCEEEEECCEEEEEEEEECCCCCCEEEEEE
VNDAFVMNAWKRDTDQRDEAVFLADGNAEFTKAIGMELDASGAGLGIRSKRYSMLVEDGK
ECCEEEEECCCCCCCCCCCEEEEECCCCCEEEEECEEECCCCCCCCCCCCEEEEEEECCC
VTKLNLEAAPGKVEVSGGDTLLGQL
EEEEEEECCCCEEEECCCCEEECCC
>Mature Secondary Structure 
TGEGPQVKTTDDIFKGKKVALFAVPGAYTGTCHKMHLPSIFLNAYALKDKGVDTIAIVS
CCCCCCEECCHHHHCCCEEEEEECCCCCCCCEEEEECCEEEEEEEEECCCCCCEEEEEE
VNDAFVMNAWKRDTDQRDEAVFLADGNAEFTKAIGMELDASGAGLGIRSKRYSMLVEDGK
ECCEEEEECCCCCCCCCCCEEEEECCCCCEEEEECEEECCCCCCCCCCCCEEEEEEECCC
VTKLNLEAAPGKVEVSGGDTLLGQL
EEEEEEECCCCEEEECCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]