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The map label for this gene is cya3 [H]

Identifier: 146343300

GI number: 146343300

Start: 6774435

End: 6776012

Strand: Direct

Name: cya3 [H]

Synonym: BRADO6523

Alternate gene names: 146343300

Gene position: 6774435-6776012 (Clockwise)

Preceding gene: 146343298

Following gene: 146343301

Centisome position: 90.85

GC content: 69.84

Gene sequence:

>1578_bases
GTGAGATTGGTCGTGCGGCAGCGATGGGCGGATGTGGTGTATCGTTTCGACGATTTCGTGCTCGATCCCGATCGCCGCGA
GCTGCGCCGTGGCGGCGATCCGGTCGCGTTGGAACCGCAGGTCTTCGACCTCATCGCGTTCCTGATCAAAGCGCGCGACC
ACGTCGTCAGCCGCGACGAGATCCTGGATGCGGTGTGGGGCGGCCGCATCGTCTCGGAGGCCACCCTGGCGAGCCGCATC
AGCGCGGCGCGCAGCGCGATCGGCGACAATGGCGAGGCGCAACGCCTGATCCGCACCTTCCCGCGCAAGGGCGTCCGTTT
CATCGCCGAAGTTCGCGAGCAGGCCGCCGTCATGGCGGCGCCTGTCATGACCACGCCACGTCTCGACGGCCCGGCCATCG
CCGTGCTTCCGTTCACCAACATGAGCGGAGATCCGGCGCAGGACTACTTCGCCGACGGCATGGTCGAGGATATCATCACG
GCGCTCTCCCGCTGCAGCGGCCTCGCGGTGATCGCGCGCAACTCGTCATTCACCTACAAGGGCCGCGCCGTGGACATCCG
CGAGGTCGGACGCGAGCTCGGCGTCGGCTATGTGCTCGAAGGCAGCGTGCGCCGCGTGGGCGAGCGGCTGCGCATCAACG
GCCAGCTGATCGACGCCGGCTCAGGCGCGCATCTCTGGGCCGACCGGTTCGACGGCGATGTGAGCGATCTGTTCGCGTTG
CAGGACCGCATCACCGAGAGTGTGGTGGCGGCGATCGAGCCGACGCTCGAGCTCGCCGAGAGCGCACGGCGCCGCGCGGC
GCCGCAGCCGCGTCCCGACGCCTATGATCTGCTGCTGCGCGCCGCCAGCCTGCGCGACGCCTTCACGCCCGAGAGCCTGA
AGGCCGCGATCGCCTGCCTGGACCACGCGCTCGCGATCGATGCTGACTATGCGCCGGCGATGGCGGCGCGCGCCTATTGT
CAGGCACTCCGGCATTTCCAGAGGTGGAGCGAGCCGGACGAGGACTATCGCGCTGACGCCGTCGCGCTGGCCTGGCGAGC
GACGGAGCGCGCGCCGGGCGATGCGCAGGTGCTGTGGATGGCGGCGTTCGCGATCTGGAACATGGCCGATGAGAGCGCGC
CTGCGCGCGAGCTGTTCAAGCGCTCGCTCGCCATCAATGCGAACTCGGCAATGGCGCTCACCATGAGCGGCTGGATCGCC
GCGATGGCGGGACAGCCGGCCGAAGGCCGCGCGATGATCGAACGTGCGCTGCGGCTGAATCCGCGCGATCCGCGCGGCTG
GTTCGCAGCCGGCGCGATGGCGATCTGCGCGCTTGCGGGGGATGATCTCGGCGGCGCCATCCGCTGGGCCGAGACGGCGC
TCGGCCAGAACCGCCGCTTCGCCGTTGCGCTGCGCGTGCTGATCGTGGCCCTGGTCAGAGCAGGTGACCTCGCCCGGGCC
ACCGGCGTCGCGCGCCAACTGTTGATCGTGGAGCCCGACCTCACCGTTTCGGGCTTCCTGGCGCGGATCCCGTTCCCGGT
GCAGACCATGGCCACAACCTATGCGGAAGCCCTGCGCGCGGCGGGCGTCCCTGCCTGA

Upstream 100 bases:

>100_bases
ACTGATGGGCCCTTGTGCGCGATGCCGGCGCGACGCGCTTGGAGGCGAGCTTGATTTTTGCTTGAGGCGAGCTTGATTTT
GCATCGGAGCTGACGCGAAG

Downstream 100 bases:

>100_bases
TCCCGCGGCGTGCAGCGGAACCGGCCGCAGCTGTCAATTCAGCCATTTTCAGCAGATCGAGACACTTGGCGAAACGACAT
TCACACTACCTTAGGTTCCA

Product: transcriptional regulator

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 3; Adenylyl cyclase 3 [H]

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MRLVVRQRWADVVYRFDDFVLDPDRRELRRGGDPVALEPQVFDLIAFLIKARDHVVSRDEILDAVWGGRIVSEATLASRI
SAARSAIGDNGEAQRLIRTFPRKGVRFIAEVREQAAVMAAPVMTTPRLDGPAIAVLPFTNMSGDPAQDYFADGMVEDIIT
ALSRCSGLAVIARNSSFTYKGRAVDIREVGRELGVGYVLEGSVRRVGERLRINGQLIDAGSGAHLWADRFDGDVSDLFAL
QDRITESVVAAIEPTLELAESARRRAAPQPRPDAYDLLLRAASLRDAFTPESLKAAIACLDHALAIDADYAPAMAARAYC
QALRHFQRWSEPDEDYRADAVALAWRATERAPGDAQVLWMAAFAIWNMADESAPARELFKRSLAINANSAMALTMSGWIA
AMAGQPAEGRAMIERALRLNPRDPRGWFAAGAMAICALAGDDLGGAIRWAETALGQNRRFAVALRVLIVALVRAGDLARA
TGVARQLLIVEPDLTVSGFLARIPFPVQTMATTYAEALRAAGVPA

Sequences:

>Translated_525_residues
MRLVVRQRWADVVYRFDDFVLDPDRRELRRGGDPVALEPQVFDLIAFLIKARDHVVSRDEILDAVWGGRIVSEATLASRI
SAARSAIGDNGEAQRLIRTFPRKGVRFIAEVREQAAVMAAPVMTTPRLDGPAIAVLPFTNMSGDPAQDYFADGMVEDIIT
ALSRCSGLAVIARNSSFTYKGRAVDIREVGRELGVGYVLEGSVRRVGERLRINGQLIDAGSGAHLWADRFDGDVSDLFAL
QDRITESVVAAIEPTLELAESARRRAAPQPRPDAYDLLLRAASLRDAFTPESLKAAIACLDHALAIDADYAPAMAARAYC
QALRHFQRWSEPDEDYRADAVALAWRATERAPGDAQVLWMAAFAIWNMADESAPARELFKRSLAINANSAMALTMSGWIA
AMAGQPAEGRAMIERALRLNPRDPRGWFAAGAMAICALAGDDLGGAIRWAETALGQNRRFAVALRVLIVALVRAGDLARA
TGVARQLLIVEPDLTVSGFLARIPFPVQTMATTYAEALRAAGVPA
>Mature_525_residues
MRLVVRQRWADVVYRFDDFVLDPDRRELRRGGDPVALEPQVFDLIAFLIKARDHVVSRDEILDAVWGGRIVSEATLASRI
SAARSAIGDNGEAQRLIRTFPRKGVRFIAEVREQAAVMAAPVMTTPRLDGPAIAVLPFTNMSGDPAQDYFADGMVEDIIT
ALSRCSGLAVIARNSSFTYKGRAVDIREVGRELGVGYVLEGSVRRVGERLRINGQLIDAGSGAHLWADRFDGDVSDLFAL
QDRITESVVAAIEPTLELAESARRRAAPQPRPDAYDLLLRAASLRDAFTPESLKAAIACLDHALAIDADYAPAMAARAYC
QALRHFQRWSEPDEDYRADAVALAWRATERAPGDAQVLWMAAFAIWNMADESAPARELFKRSLAINANSAMALTMSGWIA
AMAGQPAEGRAMIERALRLNPRDPRGWFAAGAMAICALAGDDLGGAIRWAETALGQNRRFAVALRVLIVALVRAGDLARA
TGVARQLLIVEPDLTVSGFLARIPFPVQTMATTYAEALRAAGVPA

Specific function: Required For Pcad Induction, A Promoter Upstream Of Cadb That Is Responsible For The Ph-Regulated Expression Of Cada. [C]

COG id: COG5616

COG function: function code S; Predicted integral membrane protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 5 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1790576, Length=100, Percent_Identity=32, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00515 TPR_1 [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 57118; Mature: 57118

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLVVRQRWADVVYRFDDFVLDPDRRELRRGGDPVALEPQVFDLIAFLIKARDHVVSRDE
CCCHHHHHHHHHHHHHHHHEECCCHHHHHCCCCCCEECHHHHHHHHHHHHHHHHHCCHHH
ILDAVWGGRIVSEATLASRISAARSAIGDNGEAQRLIRTFPRKGVRFIAEVREQAAVMAA
HHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC
PVMTTPRLDGPAIAVLPFTNMSGDPAQDYFADGMVEDIITALSRCSGLAVIARNSSFTYK
CCCCCCCCCCCEEEEEEECCCCCCCHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCEEEC
GRAVDIREVGRELGVGYVLEGSVRRVGERLRINGQLIDAGSGAHLWADRFDGDVSDLFAL
CCEECHHHHHHHHCCCEEECCHHHHHHHHHEECCEEEECCCCCEEEHHHCCCCHHHHHHH
QDRITESVVAAIEPTLELAESARRRAAPQPRPDAYDLLLRAASLRDAFTPESLKAAIACL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
DHALAIDADYAPAMAARAYCQALRHFQRWSEPDEDYRADAVALAWRATERAPGDAQVLWM
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEHHCCCCCCCHHHHHH
AAFAIWNMADESAPARELFKRSLAINANSAMALTMSGWIAAMAGQPAEGRAMIERALRLN
HHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCCHHHHHHHHHHCC
PRDPRGWFAAGAMAICALAGDDLGGAIRWAETALGQNRRFAVALRVLIVALVRAGDLARA
CCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHH
TGVARQLLIVEPDLTVSGFLARIPFPVQTMATTYAEALRAAGVPA
HHHHHEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRLVVRQRWADVVYRFDDFVLDPDRRELRRGGDPVALEPQVFDLIAFLIKARDHVVSRDE
CCCHHHHHHHHHHHHHHHHEECCCHHHHHCCCCCCEECHHHHHHHHHHHHHHHHHCCHHH
ILDAVWGGRIVSEATLASRISAARSAIGDNGEAQRLIRTFPRKGVRFIAEVREQAAVMAA
HHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC
PVMTTPRLDGPAIAVLPFTNMSGDPAQDYFADGMVEDIITALSRCSGLAVIARNSSFTYK
CCCCCCCCCCCEEEEEEECCCCCCCHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCEEEC
GRAVDIREVGRELGVGYVLEGSVRRVGERLRINGQLIDAGSGAHLWADRFDGDVSDLFAL
CCEECHHHHHHHHCCCEEECCHHHHHHHHHEECCEEEECCCCCEEEHHHCCCCHHHHHHH
QDRITESVVAAIEPTLELAESARRRAAPQPRPDAYDLLLRAASLRDAFTPESLKAAIACL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
DHALAIDADYAPAMAARAYCQALRHFQRWSEPDEDYRADAVALAWRATERAPGDAQVLWM
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEHHCCCCCCCHHHHHH
AAFAIWNMADESAPARELFKRSLAINANSAMALTMSGWIAAMAGQPAEGRAMIERALRLN
HHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCCHHHHHHHHHHCC
PRDPRGWFAAGAMAICALAGDDLGGAIRWAETALGQNRRFAVALRVLIVALVRAGDLARA
CCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHH
TGVARQLLIVEPDLTVSGFLARIPFPVQTMATTYAEALRAAGVPA
HHHHHEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10485295; 11481432 [H]