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The map label for this gene is mhpA [H]

Identifier: 146343103

GI number: 146343103

Start: 6540847

End: 6542484

Strand: Direct

Name: mhpA [H]

Synonym: BRADO6299

Alternate gene names: 146343103

Gene position: 6540847-6542484 (Clockwise)

Preceding gene: 146343102

Following gene: 146343104

Centisome position: 87.72

GC content: 67.58

Gene sequence:

>1638_bases
ATGAGCAACTATGTCTATCCGAGATTTCCCTACATCCGCTCGACCGAGCAGGCGAGCGGCGAGACCCGCCGCCATCCGGT
CGTCGTGATCGGCGCCGGGCCGATCGGCCTCACCGCCGCGCTCGATCTCGCCGCGCGCGGCCAGAAGGTGGTGGTGCTCG
ACGACAACGACACCGTCAGCATCGGCTCCCGCGCCGTGTGCTACGCCAAGCGCCCGCTGGAGATCTGGGACCGGCTCGGC
TGCGCCGCGCCGATGGTCGACAAGGGCGTGAGCTGGAACATCGGCAAGGTGTTTTTCCGCGACCGGCTGTCCTACCAGTT
CGACCTGCTGCCCGAGCCCGACCATCGCTGGCCGGCGATGATCAACCTGCAGCAATACTATCTCGAGGAAATATTGGTCG
ATGCCTGCAGCAGGAGCCCGCTGGTCGACCTGCGCTGGAAGCACCGGCTGGTCAGCCTCAAGCAGACCGACGACCACGCT
GTGCTCGCGTTGGAGACGCCGGACGGCATCTTCAGCATGGAAGCGCAATGGGTGATCGCCTGCGACGGCGCCAATTCCGA
CACCCGCCGGATGGTCGGCGCCGAGTTCAAGGGCCAGTTCTTCCAGGACCGCTTCCTGATCGCCGACGTCCGGATGACGG
CGGAGTTTCCGACCGAGCGGTGGTTCTGGTTCGATCCGCCGTTTCATCGGGGACAGTCGGTGCTGCTGCATCGCCAGTCC
GACAACATCTGGCGGATCGACTTCCAGCTCGGCTGGGAGGCCGATCCCGACGAGGAGAAGAAGCCCGAGCGCGTGCTCCC
GCGGATCCGCGCGATGCTCGGCGACGGCGCGGAGTTCGAGCTCGAATGGGTCTCGATCTATCAGTTCGCCTGCCGGCGCA
TCGACAATTTCCGCCACGGCCGCGTGCTGTTCGCCGGCGATGCGGCGCATCAGGTATCGCCGTTCGGCGCCCGCGGCGCC
AACACCGGCGTGCAGGATATCGACAATCTCGCCTGGAAGCTGTCGCTGGTGCTGCGCGGCGAGGCGCCGGAAAGCCTGAT
CGACAGCTATCACGAGGAGCGGGCCTACGCGGCCGACGACAACATCCTGAACTCGACCCGCGCCACCGACTTCATCACGC
CGAAGACGCAGGTCAGTCGGCATTTCCGCGACGCCGTGCTCGACCTCGCGCAGCATCACGCCTTTGCGCGGCCGCTGGTC
AACAGCGGCCGGCTGTCGACGCCGACGCCCTATGTCGCATCGTCGCTGAACACGCCCGACGGTGCGCCGGACAGCGGCGC
GATGACGCCGGGCACCAACGCGGCCGACGCGCCGGTGCGGATCGCGGGACAGCCAGGCTGGTTGCTGAACAGCCTCGGCG
CCGGCTTCACCGTGCTGACGTTCGACGAGACCGTAACCGCCAACGAGACCAGCATTGATGGCCTCGTGGCGCGCGTGCTC
GTCGCAGGCCGCGACATCGCCGACACCAAGGGGCTGCTCGCGCAGCGCTACGGCGCGGCACCCGGCACGACCTATGTGTT
CCGCCCGGATCAATACGTCACCGCCCGCTTCCCGCAGTTCGAGGAGGCCAAGATCGCCGCGGCAGTCCGGCGCGCCTGCG
GCAGGTCCGGCGTGGCCCAGCAGGAGCTTGCCGCATGA

Upstream 100 bases:

>100_bases
CAAGAAGCCGCCGCGGCACACCGCCTGGATGCACGAGAAGGAATTCGCGAGCGCCGACTGAACGAGCGTTCCTTCCCGTC
ACGCGCCAGACGAGGCCGCC

Downstream 100 bases:

>100_bases
GTCTGACCCTCACGCCGAACATCAGCGATCCCGACGACTTCTATGCCGAGCTGATCGGCAGCCAGCGCGAGCTGAGCGAG
GACGAGGCGCTGCGCATGAA

Product: FAD-dependent oxidoreductase

Products: NA

Alternate protein names: 3-HCI hydroxylase; 3-HPP hydroxylase; Flavin-type monooxygenase [H]

Number of amino acids: Translated: 545; Mature: 544

Protein sequence:

>545_residues
MSNYVYPRFPYIRSTEQASGETRRHPVVVIGAGPIGLTAALDLAARGQKVVVLDDNDTVSIGSRAVCYAKRPLEIWDRLG
CAAPMVDKGVSWNIGKVFFRDRLSYQFDLLPEPDHRWPAMINLQQYYLEEILVDACSRSPLVDLRWKHRLVSLKQTDDHA
VLALETPDGIFSMEAQWVIACDGANSDTRRMVGAEFKGQFFQDRFLIADVRMTAEFPTERWFWFDPPFHRGQSVLLHRQS
DNIWRIDFQLGWEADPDEEKKPERVLPRIRAMLGDGAEFELEWVSIYQFACRRIDNFRHGRVLFAGDAAHQVSPFGARGA
NTGVQDIDNLAWKLSLVLRGEAPESLIDSYHEERAYAADDNILNSTRATDFITPKTQVSRHFRDAVLDLAQHHAFARPLV
NSGRLSTPTPYVASSLNTPDGAPDSGAMTPGTNAADAPVRIAGQPGWLLNSLGAGFTVLTFDETVTANETSIDGLVARVL
VAGRDIADTKGLLAQRYGAAPGTTYVFRPDQYVTARFPQFEEAKIAAAVRRACGRSGVAQQELAA

Sequences:

>Translated_545_residues
MSNYVYPRFPYIRSTEQASGETRRHPVVVIGAGPIGLTAALDLAARGQKVVVLDDNDTVSIGSRAVCYAKRPLEIWDRLG
CAAPMVDKGVSWNIGKVFFRDRLSYQFDLLPEPDHRWPAMINLQQYYLEEILVDACSRSPLVDLRWKHRLVSLKQTDDHA
VLALETPDGIFSMEAQWVIACDGANSDTRRMVGAEFKGQFFQDRFLIADVRMTAEFPTERWFWFDPPFHRGQSVLLHRQS
DNIWRIDFQLGWEADPDEEKKPERVLPRIRAMLGDGAEFELEWVSIYQFACRRIDNFRHGRVLFAGDAAHQVSPFGARGA
NTGVQDIDNLAWKLSLVLRGEAPESLIDSYHEERAYAADDNILNSTRATDFITPKTQVSRHFRDAVLDLAQHHAFARPLV
NSGRLSTPTPYVASSLNTPDGAPDSGAMTPGTNAADAPVRIAGQPGWLLNSLGAGFTVLTFDETVTANETSIDGLVARVL
VAGRDIADTKGLLAQRYGAAPGTTYVFRPDQYVTARFPQFEEAKIAAAVRRACGRSGVAQQELAA
>Mature_544_residues
SNYVYPRFPYIRSTEQASGETRRHPVVVIGAGPIGLTAALDLAARGQKVVVLDDNDTVSIGSRAVCYAKRPLEIWDRLGC
AAPMVDKGVSWNIGKVFFRDRLSYQFDLLPEPDHRWPAMINLQQYYLEEILVDACSRSPLVDLRWKHRLVSLKQTDDHAV
LALETPDGIFSMEAQWVIACDGANSDTRRMVGAEFKGQFFQDRFLIADVRMTAEFPTERWFWFDPPFHRGQSVLLHRQSD
NIWRIDFQLGWEADPDEEKKPERVLPRIRAMLGDGAEFELEWVSIYQFACRRIDNFRHGRVLFAGDAAHQVSPFGARGAN
TGVQDIDNLAWKLSLVLRGEAPESLIDSYHEERAYAADDNILNSTRATDFITPKTQVSRHFRDAVLDLAQHHAFARPLVN
SGRLSTPTPYVASSLNTPDGAPDSGAMTPGTNAADAPVRIAGQPGWLLNSLGAGFTVLTFDETVTANETSIDGLVARVLV
AGRDIADTKGLLAQRYGAAPGTTYVFRPDQYVTARFPQFEEAKIAAAVRRACGRSGVAQQELAA

Specific function: Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3- hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI) [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pheA/tfdB FAD monooxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786543, Length=517, Percent_Identity=24.7582205029014, Blast_Score=141, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 60668; Mature: 60537

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNYVYPRFPYIRSTEQASGETRRHPVVVIGAGPIGLTAALDLAARGQKVVVLDDNDTVS
CCCCCCCCCCCCCCCHHCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEECCCCEEE
IGSRAVCYAKRPLEIWDRLGCAAPMVDKGVSWNIGKVFFRDRLSYQFDLLPEPDHRWPAM
CCCEEEEEECCCHHHHHHCCCCCCHHCCCCCCCHHHHHHHHCCCEEEECCCCCCCCCCEE
INLQQYYLEEILVDACSRSPLVDLRWKHRLVSLKQTDDHAVLALETPDGIFSMEAQWVIA
ECHHHHHHHHHHHHHHCCCCEEEEEHHCEEEEEEECCCCEEEEEECCCCEEEECCCEEEE
CDGANSDTRRMVGAEFKGQFFQDRFLIADVRMTAEFPTERWFWFDPPFHRGQSVLLHRQS
ECCCCCHHHHHHCCHHCCCHHHCEEEEEEEEEEECCCCCCEEEECCCCCCCCEEEEEECC
DNIWRIDFQLGWEADPDEEKKPERVLPRIRAMLGDGAEFELEWVSIYQFACRRIDNFRHG
CCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCCC
RVLFAGDAAHQVSPFGARGANTGVQDIDNLAWKLSLVLRGEAPESLIDSYHEERAYAADD
EEEEECCCCCCCCCCCCCCCCCCHHHHHHHEEEEEEEEECCCCHHHHHHHHHHCCCCCCC
NILNSTRATDFITPKTQVSRHFRDAVLDLAQHHAFARPLVNSGRLSTPTPYVASSLNTPD
CHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCC
GAPDSGAMTPGTNAADAPVRIAGQPGWLLNSLGAGFTVLTFDETVTANETSIDGLVARVL
CCCCCCCCCCCCCCCCCCEEECCCCCHHHHHCCCCEEEEEECCEECCCCCHHHHHHHHHH
VAGRDIADTKGLLAQRYGAAPGTTYVFRPDQYVTARFPQFEEAKIAAAVRRACGRSGVAQ
HHCCCCCHHHHHHHHHCCCCCCCEEEECCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCH
QELAA
HHHCC
>Mature Secondary Structure 
SNYVYPRFPYIRSTEQASGETRRHPVVVIGAGPIGLTAALDLAARGQKVVVLDDNDTVS
CCCCCCCCCCCCCCHHCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEECCCCEEE
IGSRAVCYAKRPLEIWDRLGCAAPMVDKGVSWNIGKVFFRDRLSYQFDLLPEPDHRWPAM
CCCEEEEEECCCHHHHHHCCCCCCHHCCCCCCCHHHHHHHHCCCEEEECCCCCCCCCCEE
INLQQYYLEEILVDACSRSPLVDLRWKHRLVSLKQTDDHAVLALETPDGIFSMEAQWVIA
ECHHHHHHHHHHHHHHCCCCEEEEEHHCEEEEEEECCCCEEEEEECCCCEEEECCCEEEE
CDGANSDTRRMVGAEFKGQFFQDRFLIADVRMTAEFPTERWFWFDPPFHRGQSVLLHRQS
ECCCCCHHHHHHCCHHCCCHHHCEEEEEEEEEEECCCCCCEEEECCCCCCCCEEEEEECC
DNIWRIDFQLGWEADPDEEKKPERVLPRIRAMLGDGAEFELEWVSIYQFACRRIDNFRHG
CCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCCC
RVLFAGDAAHQVSPFGARGANTGVQDIDNLAWKLSLVLRGEAPESLIDSYHEERAYAADD
EEEEECCCCCCCCCCCCCCCCCCHHHHHHHEEEEEEEEECCCCHHHHHHHHHHCCCCCCC
NILNSTRATDFITPKTQVSRHFRDAVLDLAQHHAFARPLVNSGRLSTPTPYVASSLNTPD
CHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCC
GAPDSGAMTPGTNAADAPVRIAGQPGWLLNSLGAGFTVLTFDETVTANETSIDGLVARVL
CCCCCCCCCCCCCCCCCCEEECCCCCHHHHHCCCCEEEEEECCEECCCCCHHHHHHHHHH
VAGRDIADTKGLLAQRYGAAPGTTYVFRPDQYVTARFPQFEEAKIAAAVRRACGRSGVAQ
HHCCCCCHHHHHHHHHCCCCCCCEEEECCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCH
QELAA
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA