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The map label for this gene is nhaR [H]

Identifier: 146343037

GI number: 146343037

Start: 6467349

End: 6468236

Strand: Direct

Name: nhaR [H]

Synonym: BRADO6225

Alternate gene names: 146343037

Gene position: 6467349-6468236 (Clockwise)

Preceding gene: 146343034

Following gene: 146343039

Centisome position: 86.73

GC content: 68.02

Gene sequence:

>888_bases
ATGCCGCATCTGAACTACCACCACCTGCGCTATTTCTGGATCATCGCCAGCGAAGGCAGCATGAGCCGCGCGGCGCAGCG
GCTCAACGTCTCGCCCTCCTCGCTGTCGGTGCAGGTCAAGGCGCTGGAGGACCAGCTGGGCCAGAAGCTGTTCGAGCGCA
CCGGCCGCACCCTGCAGCTGACCGAAGCCGGACGCATCGCACTCGATTATGCCGGCAGCGTGTTCAAGTCCGGCCATGAG
CTGATCGAGACGCTGTCGGGCCTGCGGCCCGGACGGCAGCTGCTGCGGGTCGGCGCCGCCGCCAATCTGTCGCGCAACTT
CCAGATCGCCTTCCTGAAGCCGTTGATCGGCCGCGGCGATGTCGAGCTGATCATCCGCACCGGCCAGTTCGCGGATCTGC
TGGAGCAGCTCGATGCGCACAAGCTCGACCTCGTGCTCGCCAACCACCCGGCGGCGCCCGATATGCGCAGCAATTTCGAG
AACACGCTGATCGATGAGCAGCGTGTCAGCCTGGTCAGCCGCAAGCCGCCCAGGCCGGCGCGCTTCCGGTTTCCCCAGGA
CCTGGCGACGACGCCGGTGATCCTGCCCGGCCGCGGCAGCGCGCTGCGCTCCGCCTTCGACGCCCTGGTCGGCTCGAGCG
GCATCCGTCCGATCATCGCCGCCGAGGTCGACGACATGGCGATGCTGCGGCTGATGGCCCGCGAGAGCGGCGCGATGACA
CTGGTGCCGTCAATCGTCGTGATCGACGAATTGCGCTCAGGCGCGCTAGTCGAGCGCGCGCGGCTCGGCGCCCTGAAGGA
GCAGTTCTTCGCCGTCAGCCAGCAGCGCCGCTACCCCAACCCGCTGGTCGCCGAGCTGATCGGACCGCGGTCCAAGAAGG
CGGAGTGA

Upstream 100 bases:

>100_bases
TGATCAAATGAGACGGTTGCTGCTTGTCTTTAACGGCCCCGAAGCCTTCTTAAAATTTCAATCATTGAACATGATCGTTA
GAAAATATAGAACGATCGCC

Downstream 100 bases:

>100_bases
GTCTCGCGCACGTCACGCAGCACAGAACGTAGAGTGGGCAAAGGCGCGCCCGACAGCCGTTGCCGTGCGCAATTCCCGCC
CGCGCCGTGCCCACCGCCGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MPHLNYHHLRYFWIIASEGSMSRAAQRLNVSPSSLSVQVKALEDQLGQKLFERTGRTLQLTEAGRIALDYAGSVFKSGHE
LIETLSGLRPGRQLLRVGAAANLSRNFQIAFLKPLIGRGDVELIIRTGQFADLLEQLDAHKLDLVLANHPAAPDMRSNFE
NTLIDEQRVSLVSRKPPRPARFRFPQDLATTPVILPGRGSALRSAFDALVGSSGIRPIIAAEVDDMAMLRLMARESGAMT
LVPSIVVIDELRSGALVERARLGALKEQFFAVSQQRRYPNPLVAELIGPRSKKAE

Sequences:

>Translated_295_residues
MPHLNYHHLRYFWIIASEGSMSRAAQRLNVSPSSLSVQVKALEDQLGQKLFERTGRTLQLTEAGRIALDYAGSVFKSGHE
LIETLSGLRPGRQLLRVGAAANLSRNFQIAFLKPLIGRGDVELIIRTGQFADLLEQLDAHKLDLVLANHPAAPDMRSNFE
NTLIDEQRVSLVSRKPPRPARFRFPQDLATTPVILPGRGSALRSAFDALVGSSGIRPIIAAEVDDMAMLRLMARESGAMT
LVPSIVVIDELRSGALVERARLGALKEQFFAVSQQRRYPNPLVAELIGPRSKKAE
>Mature_294_residues
PHLNYHHLRYFWIIASEGSMSRAAQRLNVSPSSLSVQVKALEDQLGQKLFERTGRTLQLTEAGRIALDYAGSVFKSGHEL
IETLSGLRPGRQLLRVGAAANLSRNFQIAFLKPLIGRGDVELIIRTGQFADLLEQLDAHKLDLVLANHPAAPDMRSNFEN
TLIDEQRVSLVSRKPPRPARFRFPQDLATTPVILPGRGSALRSAFDALVGSSGIRPIIAAEVDDMAMLRLMARESGAMTL
VPSIVVIDELRSGALVERARLGALKEQFFAVSQQRRYPNPLVAELIGPRSKKAE

Specific function: Plays a role in the positive regulation of nhaA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=289, Percent_Identity=29.757785467128, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI157672245, Length=249, Percent_Identity=26.1044176706827, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790399, Length=260, Percent_Identity=26.5384615384615, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1790208, Length=256, Percent_Identity=27.734375, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87081904, Length=265, Percent_Identity=28.3018867924528, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32546; Mature: 32415

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHLNYHHLRYFWIIASEGSMSRAAQRLNVSPSSLSVQVKALEDQLGQKLFERTGRTLQL
CCCCCCEEEEEEEEEECCCCHHHHHHHHCCCCCHHEEEHHHHHHHHHHHHHHHCCCEEEE
TEAGRIALDYAGSVFKSGHELIETLSGLRPGRQLLRVGAAANLSRNFQIAFLKPLIGRGD
ECCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECHHCCCCC
VELIIRTGQFADLLEQLDAHKLDLVLANHPAAPDMRSNFENTLIDEQRVSLVSRKPPRPA
EEEEEECCHHHHHHHHHCCCEEEEEEECCCCCCHHHHCHHHHHHHHHHHHHHHCCCCCCC
RFRFPQDLATTPVILPGRGSALRSAFDALVGSSGIRPIIAAEVDDMAMLRLMARESGAMT
CCCCCHHHCCCCEEECCCCHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHCCCCEE
LVPSIVVIDELRSGALVERARLGALKEQFFAVSQQRRYPNPLVAELIGPRSKKAE
EHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PHLNYHHLRYFWIIASEGSMSRAAQRLNVSPSSLSVQVKALEDQLGQKLFERTGRTLQL
CCCCCEEEEEEEEEECCCCHHHHHHHHCCCCCHHEEEHHHHHHHHHHHHHHHCCCEEEE
TEAGRIALDYAGSVFKSGHELIETLSGLRPGRQLLRVGAAANLSRNFQIAFLKPLIGRGD
ECCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECHHCCCCC
VELIIRTGQFADLLEQLDAHKLDLVLANHPAAPDMRSNFENTLIDEQRVSLVSRKPPRPA
EEEEEECCHHHHHHHHHCCCEEEEEEECCCCCCHHHHCHHHHHHHHHHHHHHHCCCCCCC
RFRFPQDLATTPVILPGRGSALRSAFDALVGSSGIRPIIAAEVDDMAMLRLMARESGAMT
CCCCCHHHCCCCEEECCCCHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHCCCCEE
LVPSIVVIDELRSGALVERARLGALKEQFFAVSQQRRYPNPLVAELIGPRSKKAE
EHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2429258; 1630901; 9278503; 3413113; 1316901; 8168494 [H]