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The map label for this gene is exoB [H]

Identifier: 146342982

GI number: 146342982

Start: 6391105

End: 6392100

Strand: Reverse

Name: exoB [H]

Synonym: BRADO6165

Alternate gene names: 146342982

Gene position: 6392100-6391105 (Counterclockwise)

Preceding gene: 146342986

Following gene: 146342977

Centisome position: 85.72

GC content: 67.37

Gene sequence:

>996_bases
ATGAGTACGAAAGGCGCGATCCTGATCGCCGGCGGCGCCGGCTATATCGGAGCTCATTGCAGCAAGGCGGTCGCCGAAGC
CGGCTTCACGCCGGTCGTCTATGACAATCTGACGACGGGCCATCGCGGCTTCGTGCAATGGGGGCCGCTGATGGTCGGCG
ATATCGCCGACAGCATCAAGATCGCGAGCACGATCCGGCAATACGACGTCAAGGCGGTGATGCACTTCGCGGCCTGGAGC
GCCGTCGGCGAGTCGGTGGCCGATCCGCAGAAATATTACCTCAACAACGTCGCCGGCACGCTGGGCCTGTTGCAGGGCAT
GCGCGAGGCCGGCTGCACGCGGCTCGTGTTCTCCTCGACCGGCGCAGTCTACGGCAATGCCGGGCGCGAGCCGATCCCGG
AGAGCGCGGCGGGGCCGACCGTCAATCCTTACGGCCGTTCCAAATACATGATCGAGCAGATCCTGGCCGACTATCGCGCC
GCCTACGGCTTCTCCGCCACCGCGCTGCGCTACTTCAACGCCTGCGGCGCCGACGCGTCAGGCACGATCGGCGAGTTGCG
CGATCCCGAGACGCATCTGATTCCGCGCGCGCTGATGGCGATCCTCGGGCACGTGCCCGACTTCGCGATCTTCGGCACCG
ACTACGAGACACCTGACGGCACCGCAGTGCGCGATTACATTCACGTCGACGACCTCGCCGCCGCCCATATCGCCGCGCTC
GGCCGGCTGCTGGAAGGGGGTGCCGGCGGCGCCTACAATCTGGGGACCGGCAGCGGCTATTCCGTGCGCGAGATCGTCGA
TGCGATCCGCAACGAGACCGGCGAGCAGGTGCCGCTGGTTTATCGCGAGCGCCGCGCCGGCGATCCGCCGATCCTGGTCG
CCGATCCCACCCGCGCCGAGCAGGAACTCGGCTTCAAGGCGCGCCGCTCCGATCTCGGCCACGTCATCCGCTCGGCCTGG
GCCTGGCATCAGAAGGCGCATCCGCGCATCGTCTGA

Upstream 100 bases:

>100_bases
CAGGTAGTTGAATTTGCTCCGACTGCAACGCTCGCTTATGGTGCTTGGTATTTGGCGCTCAGCTTCATCCATTGATTGCA
GGTAAAGGGCATAACGACTC

Downstream 100 bases:

>100_bases
GCGCGACGTGTCCGCGCCTGTCGCGGGACAGGTTACGCCGCCGCCGGCGGCGTGTGCGCGAACGCGTCCATCACGATCAT
TTCCGCGTGCTCGTCGTCGA

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSTKGAILIAGGAGYIGAHCSKAVAEAGFTPVVYDNLTTGHRGFVQWGPLMVGDIADSIKIASTIRQYDVKAVMHFAAWS
AVGESVADPQKYYLNNVAGTLGLLQGMREAGCTRLVFSSTGAVYGNAGREPIPESAAGPTVNPYGRSKYMIEQILADYRA
AYGFSATALRYFNACGADASGTIGELRDPETHLIPRALMAILGHVPDFAIFGTDYETPDGTAVRDYIHVDDLAAAHIAAL
GRLLEGGAGGAYNLGTGSGYSVREIVDAIRNETGEQVPLVYRERRAGDPPILVADPTRAEQELGFKARRSDLGHVIRSAW
AWHQKAHPRIV

Sequences:

>Translated_331_residues
MSTKGAILIAGGAGYIGAHCSKAVAEAGFTPVVYDNLTTGHRGFVQWGPLMVGDIADSIKIASTIRQYDVKAVMHFAAWS
AVGESVADPQKYYLNNVAGTLGLLQGMREAGCTRLVFSSTGAVYGNAGREPIPESAAGPTVNPYGRSKYMIEQILADYRA
AYGFSATALRYFNACGADASGTIGELRDPETHLIPRALMAILGHVPDFAIFGTDYETPDGTAVRDYIHVDDLAAAHIAAL
GRLLEGGAGGAYNLGTGSGYSVREIVDAIRNETGEQVPLVYRERRAGDPPILVADPTRAEQELGFKARRSDLGHVIRSAW
AWHQKAHPRIV
>Mature_330_residues
STKGAILIAGGAGYIGAHCSKAVAEAGFTPVVYDNLTTGHRGFVQWGPLMVGDIADSIKIASTIRQYDVKAVMHFAAWSA
VGESVADPQKYYLNNVAGTLGLLQGMREAGCTRLVFSSTGAVYGNAGREPIPESAAGPTVNPYGRSKYMIEQILADYRAA
YGFSATALRYFNACGADASGTIGELRDPETHLIPRALMAILGHVPDFAIFGTDYETPDGTAVRDYIHVDDLAAAHIAALG
RLLEGGAGGAYNLGTGSGYSVREIVDAIRNETGEQVPLVYRERRAGDPPILVADPTRAEQELGFKARRSDLGHVIRSAWA
WHQKAHPRIV

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=344, Percent_Identity=41.2790697674419, Blast_Score=236, Evalue=1e-62,
Organism=Homo sapiens, GI56118217, Length=344, Percent_Identity=41.2790697674419, Blast_Score=236, Evalue=1e-62,
Organism=Homo sapiens, GI189083684, Length=344, Percent_Identity=41.2790697674419, Blast_Score=236, Evalue=1e-62,
Organism=Homo sapiens, GI7657641, Length=288, Percent_Identity=25.6944444444444, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI42516563, Length=315, Percent_Identity=24.7619047619048, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=38.6904761904762, Blast_Score=221, Evalue=4e-59,
Organism=Escherichia coli, GI1790049, Length=267, Percent_Identity=27.7153558052434, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788353, Length=353, Percent_Identity=26.628895184136, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI48994969, Length=286, Percent_Identity=25.5244755244755, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788365, Length=294, Percent_Identity=23.8095238095238, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71982035, Length=341, Percent_Identity=37.2434017595308, Blast_Score=212, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI71982038, Length=343, Percent_Identity=37.3177842565598, Blast_Score=212, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17568069, Length=335, Percent_Identity=26.865671641791, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17539532, Length=313, Percent_Identity=23.3226837060703, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=345, Percent_Identity=39.1304347826087, Blast_Score=209, Evalue=5e-55,
Organism=Drosophila melanogaster, GI19923002, Length=340, Percent_Identity=36.4705882352941, Blast_Score=213, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35295; Mature: 35164

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTKGAILIAGGAGYIGAHCSKAVAEAGFTPVVYDNLTTGHRGFVQWGPLMVGDIADSIK
CCCCCCEEEECCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCEEECCEEEHHHHHHHH
IASTIRQYDVKAVMHFAAWSAVGESVADPQKYYLNNVAGTLGLLQGMREAGCTRLVFSST
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
GAVYGNAGREPIPESAAGPTVNPYGRSKYMIEQILADYRAAYGFSATALRYFNACGADAS
CCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
GTIGELRDPETHLIPRALMAILGHVPDFAIFGTDYETPDGTAVRDYIHVDDLAAAHIAAL
CCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GRLLEGGAGGAYNLGTGSGYSVREIVDAIRNETGEQVPLVYRERRAGDPPILVADPTRAE
HHHHHCCCCCCEECCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHCCCCCCEEEECCCCHH
QELGFKARRSDLGHVIRSAWAWHQKAHPRIV
HHHCHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
STKGAILIAGGAGYIGAHCSKAVAEAGFTPVVYDNLTTGHRGFVQWGPLMVGDIADSIK
CCCCCEEEECCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCEEECCEEEHHHHHHHH
IASTIRQYDVKAVMHFAAWSAVGESVADPQKYYLNNVAGTLGLLQGMREAGCTRLVFSST
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
GAVYGNAGREPIPESAAGPTVNPYGRSKYMIEQILADYRAAYGFSATALRYFNACGADAS
CCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
GTIGELRDPETHLIPRALMAILGHVPDFAIFGTDYETPDGTAVRDYIHVDDLAAAHIAAL
CCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GRLLEGGAGGAYNLGTGSGYSVREIVDAIRNETGEQVPLVYRERRAGDPPILVADPTRAE
HHHHHCCCCCCEECCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHCCCCCCEEEECCCCHH
QELGFKARRSDLGHVIRSAWAWHQKAHPRIV
HHHCHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9236769 [H]