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The map label for this gene is livH [H]

Identifier: 146342686

GI number: 146342686

Start: 6070357

End: 6071280

Strand: Reverse

Name: livH [H]

Synonym: BRADO5853

Alternate gene names: 146342686

Gene position: 6071280-6070357 (Counterclockwise)

Preceding gene: 146342687

Following gene: 146342685

Centisome position: 81.42

GC content: 66.56

Gene sequence:

>924_bases
GTGATGCTGATGTTCACCCTGCAGCTCATGGTCGCGGGCATCGCGACCGGCAGCGTCTACGCGCTCATCGCGCTCGGCAT
CGTGCTGATCTACAAATGCTCCGGCGTCGTCAACTTCGCGCAGGGCGCCTTCGTGATGCTCGGGGCCTACCTGACCTATG
GCCTGGTGAAGCTCGGGCTGCCGCCTTACGTCGCGCTCCTCGGCGCGATGATCCTGATGGCGGGCTGCGGTGTCGCCTCG
GAGCGGCTCGTGCTGCGCCCCATGATGAAGGCGCCGCTGGTCGCCGTGATGACGGTGACGCTCGGCATGCTGATCCTTGT
CAAGGCGGTGTGCCTGGCCGTCTGGGGACCGGATCAGCTTGCGTTTCCGCGCTTGTTCCCGGACGGCGCGCTCGATGTCT
TCGGCATCTTCATCACCTATAATTATCTCGCGGCGTTCGTGCTCTCGATCTGCCTCAGCGTCGGCTTCCTGGCGTTTTAC
CAGCTGACGCCGATCGGCCTGATGCAGCGCTGCACGGCCGACAATCCGCGGGCGGCGCTGGCGATCGGCATCCACACCAG
CAACCAGATCTCGCTGGCATGGTCGATGTCGGCGGCACTCGCCGGCATCGGCGGCGCGCTGCTGGCCTCTCTCAACGGCC
TGTCGCTCGGACTGTCCGACATCGGCCTGGTCGCCTTTCCCGTCATCGTGCTCGGCGGGCTGACGAGCCTGACCGGAGCG
CTGGTCGCCGGCCTCCTGCTGGGCGTGCTGCAGGCGCTGACCGACGGTTTGCTGACGCCGGTCGCCGAGCAGTTCCTGCG
CACCCACACCTCGATCTACTCCGCCGGCGCCCTGCAGCAGGTCGTGCCCTATGCGCTGCTCGTTGTCGTTCTGCTGGTGC
GGCCCGAAGGCATTTTCGGCCAGCGTGGCACGGAAAGGCTCTGA

Upstream 100 bases:

>100_bases
ACCGCATCGTCGTGATGGCCGCCGGGGCGCGGATCTTCGAGGGATCGCCCGCGCAAGTGCAGTCCGATCCGTCGGTCCGT
CGCGTCTATCTGGGAGAGCC

Downstream 100 bases:

>100_bases
CATGTCGCGGAGCGTGATCGCCGCCGTCATTCTCGCGGTTCTCGCGATCCTGGGCACGCTGCTGCTCGGCCGCTTCGGCG
CCTACCTGATGCATGCGGTT

Product: putative branched-chain amino acid ABC transporter permease

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein H [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MMLMFTLQLMVAGIATGSVYALIALGIVLIYKCSGVVNFAQGAFVMLGAYLTYGLVKLGLPPYVALLGAMILMAGCGVAS
ERLVLRPMMKAPLVAVMTVTLGMLILVKAVCLAVWGPDQLAFPRLFPDGALDVFGIFITYNYLAAFVLSICLSVGFLAFY
QLTPIGLMQRCTADNPRAALAIGIHTSNQISLAWSMSAALAGIGGALLASLNGLSLGLSDIGLVAFPVIVLGGLTSLTGA
LVAGLLLGVLQALTDGLLTPVAEQFLRTHTSIYSAGALQQVVPYALLVVVLLVRPEGIFGQRGTERL

Sequences:

>Translated_307_residues
MMLMFTLQLMVAGIATGSVYALIALGIVLIYKCSGVVNFAQGAFVMLGAYLTYGLVKLGLPPYVALLGAMILMAGCGVAS
ERLVLRPMMKAPLVAVMTVTLGMLILVKAVCLAVWGPDQLAFPRLFPDGALDVFGIFITYNYLAAFVLSICLSVGFLAFY
QLTPIGLMQRCTADNPRAALAIGIHTSNQISLAWSMSAALAGIGGALLASLNGLSLGLSDIGLVAFPVIVLGGLTSLTGA
LVAGLLLGVLQALTDGLLTPVAEQFLRTHTSIYSAGALQQVVPYALLVVVLLVRPEGIFGQRGTERL
>Mature_307_residues
MMLMFTLQLMVAGIATGSVYALIALGIVLIYKCSGVVNFAQGAFVMLGAYLTYGLVKLGLPPYVALLGAMILMAGCGVAS
ERLVLRPMMKAPLVAVMTVTLGMLILVKAVCLAVWGPDQLAFPRLFPDGALDVFGIFITYNYLAAFVLSICLSVGFLAFY
QLTPIGLMQRCTADNPRAALAIGIHTSNQISLAWSMSAALAGIGGALLASLNGLSLGLSDIGLVAFPVIVLGGLTSLTGA
LVAGLLLGVLQALTDGLLTPVAEQFLRTHTSIYSAGALQQVVPYALLVVVLLVRPEGIFGQRGTERL

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=321, Percent_Identity=28.6604361370716, Blast_Score=108, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 32037; Mature: 32037

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLMFTLQLMVAGIATGSVYALIALGIVLIYKCSGVVNFAQGAFVMLGAYLTYGLVKLGL
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
PPYVALLGAMILMAGCGVASERLVLRPMMKAPLVAVMTVTLGMLILVKAVCLAVWGPDQL
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AFPRLFPDGALDVFGIFITYNYLAAFVLSICLSVGFLAFYQLTPIGLMQRCTADNPRAAL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCEEE
AIGIHTSNQISLAWSMSAALAGIGGALLASLNGLSLGLSDIGLVAFPVIVLGGLTSLTGA
EEEEECCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LVAGLLLGVLQALTDGLLTPVAEQFLRTHTSIYSAGALQQVVPYALLVVVLLVRPEGIFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QRGTERL
CCCCCCC
>Mature Secondary Structure
MMLMFTLQLMVAGIATGSVYALIALGIVLIYKCSGVVNFAQGAFVMLGAYLTYGLVKLGL
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
PPYVALLGAMILMAGCGVASERLVLRPMMKAPLVAVMTVTLGMLILVKAVCLAVWGPDQL
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AFPRLFPDGALDVFGIFITYNYLAAFVLSICLSVGFLAFYQLTPIGLMQRCTADNPRAAL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCEEE
AIGIHTSNQISLAWSMSAALAGIGGALLASLNGLSLGLSDIGLVAFPVIVLGGLTSLTGA
EEEEECCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LVAGLLLGVLQALTDGLLTPVAEQFLRTHTSIYSAGALQQVVPYALLVVVLLVRPEGIFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QRGTERL
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]