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The map label for this gene is murC [H]

Identifier: 146342497

GI number: 146342497

Start: 5850906

End: 5852309

Strand: Reverse

Name: murC [H]

Synonym: BRADO5658

Alternate gene names: 146342497

Gene position: 5852309-5850906 (Counterclockwise)

Preceding gene: 146342498

Following gene: 146342496

Centisome position: 78.49

GC content: 66.24

Gene sequence:

>1404_bases
ATGAGACTGCCGCGCGAGATCGGACCCATCCACTTCGTCGGGATCGGCGGCATCGGCATGAGCGGCATCGCGGAGGTGCT
GTGCAATCTCGGCTACACGGTGCAGGGCTCCGACGCCTCGGACAATGCCAACGTCGCGCGGCTGCGCGAGAAGGGCATCA
CGGTCAGCGTCGGTCACAAGGCGGAGAACGTCGCAGGTGCCGATGTGGTCGTCGTCTCGACCGCGATCAAGCGTGACAAT
CCCGAGTTGATGGCCGCGCGCGCGCAGCGTATCCCCGTCGTCCGGCGGGCAGAGATGCTGGCCGAGCTGATGCGGCTGAA
GAGCTGCGTCGCCATCGCCGGCACCCATGGCAAGACCACGACCACCTCGATGGTCGCGGCGCTGCTCGATGCCGGCGGGC
TCGATCCCACGGTCATCAACGGCGGCATCATCAACGCCTATGGCACCAATGCGCGGCTCGGCGGCGGCGAGTGGATGGTG
GTGGAAGCCGACGAGAGCGACGGCACCTTCCTGAAGCTGCCGGCTGATGTCGCCATCGTCACCAATGTCGATCCCGAGCA
TCTCGACCACTTCAAGACCTTCGAAGCCGTGCAGGACGCCTTCCGCGCCTTCGTCGAGAACGTCCCGTTCTACGGCTTCG
CCGTGATGTGCATCGATCATCCGGTGGTGCAGGCGCTGGTCGGCAAGATCGAGGACCGCCGCATCATCACCTATGGCGTG
AACCCGCAGGCAGATGTCCGGCTGGTGGATCTCACGCCGATGGGCGGCGGCTCGTCGTTCAAGGTCGTGTTCCGCGACCG
CAAGAGTGGCGCGACGCATGAGATTTCAGACATCGTCCTGCCGATGCCCGGCCGTCACAATGCCTCGAACGCAACGGCCG
CCATCGCAGTGGCGCGCGAACTCGGCCTTTCGGACGAGGCCATCCGCAAGGCGATCGGCGGCTTCGGCGGCGTCAAGCGC
CGCTTCACCCGCACTGGCGAATGGAACGGCGTGACCGTGATCGACGACTACGGCCACCATCCCGTCGAGATCGCAGCCGT
GCTGAAGGCGGCGCGCGAATCCAGCAATGGCAAGGTCGTTGCCGTGGTGCAGCCCCATCGCTACACAAGGCTGCAGTCGT
TGTTCGAGGAGTTCTGCACCTGCTTCAACGATGCGGACGCGGTCGTCGTCGCCGACGTCTATCCGGCCGGCGAGGCGCCG
ATCGAGGGCATCGACCGCGATCATTTCGTGCTCGGTCTGCGCGCCCACGGCCATCGCGACGTGCTGCCGCTGCCGAAGGC
CGCCGATCTCGCCGGCATCGTGAAGGACCTCGCCAAGCCGGGCGACCTCGTCGTCTGCCTCGGCGCCGGCAACATCACGC
AATGGGCCTACGCGCTGCCGAACGAGTTGAAGGCGCTGGGGTAG

Upstream 100 bases:

>100_bases
GCACTTGTCCCGGCCTGTCATGTCTTGCATGAAGGGCGGATGATTCGGGGCGCGGCGGGCCCGAGCCGGGCGCCCCGCGA
GACCATGGACGGGATGCCTC

Downstream 100 bases:

>100_bases
GGCGGTGAGCTTTCCCGACATCACGCCCGATCTGAAGGCCGCGATGCCCGCGCTGCGCGGACGTCTGCTCGCCAATGAAA
GCCTCGCGCCGCTCACCTGG

Product: UDP-N-acetylmuramate--L-alanine ligase

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MRLPREIGPIHFVGIGGIGMSGIAEVLCNLGYTVQGSDASDNANVARLREKGITVSVGHKAENVAGADVVVVSTAIKRDN
PELMAARAQRIPVVRRAEMLAELMRLKSCVAIAGTHGKTTTTSMVAALLDAGGLDPTVINGGIINAYGTNARLGGGEWMV
VEADESDGTFLKLPADVAIVTNVDPEHLDHFKTFEAVQDAFRAFVENVPFYGFAVMCIDHPVVQALVGKIEDRRIITYGV
NPQADVRLVDLTPMGGGSSFKVVFRDRKSGATHEISDIVLPMPGRHNASNATAAIAVARELGLSDEAIRKAIGGFGGVKR
RFTRTGEWNGVTVIDDYGHHPVEIAAVLKAARESSNGKVVAVVQPHRYTRLQSLFEEFCTCFNDADAVVVADVYPAGEAP
IEGIDRDHFVLGLRAHGHRDVLPLPKAADLAGIVKDLAKPGDLVVCLGAGNITQWAYALPNELKALG

Sequences:

>Translated_467_residues
MRLPREIGPIHFVGIGGIGMSGIAEVLCNLGYTVQGSDASDNANVARLREKGITVSVGHKAENVAGADVVVVSTAIKRDN
PELMAARAQRIPVVRRAEMLAELMRLKSCVAIAGTHGKTTTTSMVAALLDAGGLDPTVINGGIINAYGTNARLGGGEWMV
VEADESDGTFLKLPADVAIVTNVDPEHLDHFKTFEAVQDAFRAFVENVPFYGFAVMCIDHPVVQALVGKIEDRRIITYGV
NPQADVRLVDLTPMGGGSSFKVVFRDRKSGATHEISDIVLPMPGRHNASNATAAIAVARELGLSDEAIRKAIGGFGGVKR
RFTRTGEWNGVTVIDDYGHHPVEIAAVLKAARESSNGKVVAVVQPHRYTRLQSLFEEFCTCFNDADAVVVADVYPAGEAP
IEGIDRDHFVLGLRAHGHRDVLPLPKAADLAGIVKDLAKPGDLVVCLGAGNITQWAYALPNELKALG
>Mature_467_residues
MRLPREIGPIHFVGIGGIGMSGIAEVLCNLGYTVQGSDASDNANVARLREKGITVSVGHKAENVAGADVVVVSTAIKRDN
PELMAARAQRIPVVRRAEMLAELMRLKSCVAIAGTHGKTTTTSMVAALLDAGGLDPTVINGGIINAYGTNARLGGGEWMV
VEADESDGTFLKLPADVAIVTNVDPEHLDHFKTFEAVQDAFRAFVENVPFYGFAVMCIDHPVVQALVGKIEDRRIITYGV
NPQADVRLVDLTPMGGGSSFKVVFRDRKSGATHEISDIVLPMPGRHNASNATAAIAVARELGLSDEAIRKAIGGFGGVKR
RFTRTGEWNGVTVIDDYGHHPVEIAAVLKAARESSNGKVVAVVQPHRYTRLQSLFEEFCTCFNDADAVVVADVYPAGEAP
IEGIDRDHFVLGLRAHGHRDVLPLPKAADLAGIVKDLAKPGDLVVCLGAGNITQWAYALPNELKALG

Specific function: Cell wall formation [H]

COG id: COG0773

COG function: function code M; UDP-N-acetylmuramate-alanine ligase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

Organism=Escherichia coli, GI1786279, Length=466, Percent_Identity=46.137339055794, Blast_Score=348, Evalue=4e-97,
Organism=Escherichia coli, GI1790680, Length=459, Percent_Identity=29.4117647058824, Blast_Score=160, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.8 [H]

Molecular weight: Translated: 49702; Mature: 49702

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLPREIGPIHFVGIGGIGMSGIAEVLCNLGYTVQGSDASDNANVARLREKGITVSVGHK
CCCCCHHCCEEEEEECCCCHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHCCCEEEECCC
AENVAGADVVVVSTAIKRDNPELMAARAQRIPVVRRAEMLAELMRLKSCVAIAGTHGKTT
CCCCCCCCEEEEEEHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEECCCCCCH
TTSMVAALLDAGGLDPTVINGGIINAYGTNARLGGGEWMVVEADESDGTFLKLPADVAIV
HHHHHHHHHHCCCCCCEEECCCEEEECCCCCEECCCEEEEEEECCCCCCEEEECCCEEEE
TNVDPEHLDHFKTFEAVQDAFRAFVENVPFYGFAVMCIDHPVVQALVGKIEDRRIITYGV
ECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHCCCCCCEEEEECC
NPQADVRLVDLTPMGGGSSFKVVFRDRKSGATHEISDIVLPMPGRHNASNATAAIAVARE
CCCCCEEEEEEEECCCCCEEEEEEEECCCCCCEECCEEEECCCCCCCCCCHHHHHHHHHH
LGLSDEAIRKAIGGFGGVKRRFTRTGEWNGVTVIDDYGHHPVEIAAVLKAARESSNGKVV
HCCCHHHHHHHHCCCCHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEE
AVVQPHRYTRLQSLFEEFCTCFNDADAVVVADVYPAGEAPIEGIDRDHFVLGLRAHGHRD
EEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEEEEEECCCCC
VLPLPKAADLAGIVKDLAKPGDLVVCLGAGNITQWAYALPNELKALG
CCCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHCCHHHHCCC
>Mature Secondary Structure
MRLPREIGPIHFVGIGGIGMSGIAEVLCNLGYTVQGSDASDNANVARLREKGITVSVGHK
CCCCCHHCCEEEEEECCCCHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHCCCEEEECCC
AENVAGADVVVVSTAIKRDNPELMAARAQRIPVVRRAEMLAELMRLKSCVAIAGTHGKTT
CCCCCCCCEEEEEEHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEECCCCCCH
TTSMVAALLDAGGLDPTVINGGIINAYGTNARLGGGEWMVVEADESDGTFLKLPADVAIV
HHHHHHHHHHCCCCCCEEECCCEEEECCCCCEECCCEEEEEEECCCCCCEEEECCCEEEE
TNVDPEHLDHFKTFEAVQDAFRAFVENVPFYGFAVMCIDHPVVQALVGKIEDRRIITYGV
ECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHCCCCCCEEEEECC
NPQADVRLVDLTPMGGGSSFKVVFRDRKSGATHEISDIVLPMPGRHNASNATAAIAVARE
CCCCCEEEEEEEECCCCCEEEEEEEECCCCCCEECCEEEECCCCCCCCCCHHHHHHHHHH
LGLSDEAIRKAIGGFGGVKRRFTRTGEWNGVTVIDDYGHHPVEIAAVLKAARESSNGKVV
HCCCHHHHHHHHCCCCHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEE
AVVQPHRYTRLQSLFEEFCTCFNDADAVVVADVYPAGEAPIEGIDRDHFVLGLRAHGHRD
EEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEEEEEECCCCC
VLPLPKAADLAGIVKDLAKPGDLVVCLGAGNITQWAYALPNELKALG
CCCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA