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The map label for this gene is prmA [H]

Identifier: 146342484

GI number: 146342484

Start: 5832534

End: 5833430

Strand: Direct

Name: prmA [H]

Synonym: BRADO5644

Alternate gene names: 146342484

Gene position: 5832534-5833430 (Clockwise)

Preceding gene: 146342482

Following gene: 146342486

Centisome position: 78.22

GC content: 66.33

Gene sequence:

>897_bases
ATGACATCAGATTCCCCGCCGGCGACGTACAAAGCGAGCTTCACGGTCGCGGACGAGGGCGCCGCGCGGCCGGCGGTCGA
TAGTCTGACGGAGGTCTTCTTCGAGGGAGACGCAGCGGTGGCCGCGTTCGAGCGGCCGGATGGGCGCTGGGACGTCACGG
TGCATTTCGCCGATCCTCCGGACCAGGCCCTGTTGCGCAAGCTGATCGGCGGAGCGGCGGGAACAGAGGCTGCGGGAACC
CTGACGTTCGAGACGGTTGAAGTCAAGGACTGGGTCAAGGCAAGCCTGGACGATCTGGTTCCCGTGCCGGCCGCACGCTT
CATGGTTCATGGCGCTCACGACCGGGCTCGGGTTCCGGCCAACAAGATCGGCATTGAAATCGAGGCGGCGCTCGCCTTCG
GAACCGGCCATCATGGAACCACCCGCGGCTGCCTGCTGCTGCTCGACCATGTTCTGAAACGAGGGTCGCCGCAACGCGTC
CTCGACCTCGGCACCGGAACCGGCGTCCTTGCAATTGCAGCCGCCAAGGCGACCCGCCGCTCCGTGCTGGGCAGCGACAT
CGATGCGCCCTCCGTGAGCGTTGCGCGGGAGAACGCCCGGCTCAACGGCGCAGGCCCCCTGGTCCAGGTCATCCGCGCCA
CCGGCTTTGCGGCGGCGGAATTTGCCGAAGCAGGCCCGTTCGATCTGGTGTTGGCGAACATCCTCGCCAATCCGCTGCGG
CAACTGGCGGCGCCAATGCAGCGCCACCTTGCGCCAGGGGCGAACGTGATCCTGTCAGGTCTCCTGACCCCACAAGCCCG
CGGCGTTCTTGCAGCCTATCGCGCACGCGGGCTGGTTCCGATCCGGCATCTGACAATCGAGGGGTGGAGCAGCTTGTTGC
TGCAGAAGAAACAATGA

Upstream 100 bases:

>100_bases
CCGAAAGCTGCAGCAAACATCGTCCTGCCTTAGCCAAAGCGCTTGCGCTGGCGGTCAGATTGCTTAACCACGCCAACAAA
TCAGCTTCGGACCCTGCCAG

Downstream 100 bases:

>100_bases
GATCCGATCAGCTCCGCTGGTCGGCCAAGGATTGAACCAAGGGCAGCAAATTCAGAACGATCAGGCCGAAGACGATTATG
TCTTGGGCTGGCCTTTTTGA

Product: ribosomal protein L11 methyltransferase (L11 Mtase)

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MTSDSPPATYKASFTVADEGAARPAVDSLTEVFFEGDAAVAAFERPDGRWDVTVHFADPPDQALLRKLIGGAAGTEAAGT
LTFETVEVKDWVKASLDDLVPVPAARFMVHGAHDRARVPANKIGIEIEAALAFGTGHHGTTRGCLLLLDHVLKRGSPQRV
LDLGTGTGVLAIAAAKATRRSVLGSDIDAPSVSVARENARLNGAGPLVQVIRATGFAAAEFAEAGPFDLVLANILANPLR
QLAAPMQRHLAPGANVILSGLLTPQARGVLAAYRARGLVPIRHLTIEGWSSLLLQKKQ

Sequences:

>Translated_298_residues
MTSDSPPATYKASFTVADEGAARPAVDSLTEVFFEGDAAVAAFERPDGRWDVTVHFADPPDQALLRKLIGGAAGTEAAGT
LTFETVEVKDWVKASLDDLVPVPAARFMVHGAHDRARVPANKIGIEIEAALAFGTGHHGTTRGCLLLLDHVLKRGSPQRV
LDLGTGTGVLAIAAAKATRRSVLGSDIDAPSVSVARENARLNGAGPLVQVIRATGFAAAEFAEAGPFDLVLANILANPLR
QLAAPMQRHLAPGANVILSGLLTPQARGVLAAYRARGLVPIRHLTIEGWSSLLLQKKQ
>Mature_297_residues
TSDSPPATYKASFTVADEGAARPAVDSLTEVFFEGDAAVAAFERPDGRWDVTVHFADPPDQALLRKLIGGAAGTEAAGTL
TFETVEVKDWVKASLDDLVPVPAARFMVHGAHDRARVPANKIGIEIEAALAFGTGHHGTTRGCLLLLDHVLKRGSPQRVL
DLGTGTGVLAIAAAKATRRSVLGSDIDAPSVSVARENARLNGAGPLVQVIRATGFAAAEFAEAGPFDLVLANILANPLRQ
LAAPMQRHLAPGANVILSGLLTPQARGVLAAYRARGLVPIRHLTIEGWSSLLLQKKQ

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=161, Percent_Identity=34.7826086956522, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 31259; Mature: 31128

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSDSPPATYKASFTVADEGAARPAVDSLTEVFFEGDAAVAAFERPDGRWDVTVHFADPP
CCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCC
DQALLRKLIGGAAGTEAAGTLTFETVEVKDWVKASLDDLVPVPAARFMVHGAHDRARVPA
HHHHHHHHHCCCCCCCCCCEEEEEEEEHHHHHHHHHHHCCCCCHHHHEEECCCCCCCCCH
NKIGIEIEAALAFGTGHHGTTRGCLLLLDHVLKRGSPQRVLDLGTGTGVLAIAAAKATRR
HHHCEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEHHHHHHHH
SVLGSDIDAPSVSVARENARLNGAGPLVQVIRATGFAAAEFAEAGPFDLVLANILANPLR
HHHCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHH
QLAAPMQRHLAPGANVILSGLLTPQARGVLAAYRARGLVPIRHLTIEGWSSLLLQKKQ
HHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEHHHHHHHHHCCCC
>Mature Secondary Structure 
TSDSPPATYKASFTVADEGAARPAVDSLTEVFFEGDAAVAAFERPDGRWDVTVHFADPP
CCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCC
DQALLRKLIGGAAGTEAAGTLTFETVEVKDWVKASLDDLVPVPAARFMVHGAHDRARVPA
HHHHHHHHHCCCCCCCCCCEEEEEEEEHHHHHHHHHHHCCCCCHHHHEEECCCCCCCCCH
NKIGIEIEAALAFGTGHHGTTRGCLLLLDHVLKRGSPQRVLDLGTGTGVLAIAAAKATRR
HHHCEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEHHHHHHHH
SVLGSDIDAPSVSVARENARLNGAGPLVQVIRATGFAAAEFAEAGPFDLVLANILANPLR
HHHCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHH
QLAAPMQRHLAPGANVILSGLLTPQARGVLAAYRARGLVPIRHLTIEGWSSLLLQKKQ
HHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]