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The map label for this gene is moxY [H]

Identifier: 146342303

GI number: 146342303

Start: 5643166

End: 5644530

Strand: Reverse

Name: moxY [H]

Synonym: BRADO5458

Alternate gene names: 146342303

Gene position: 5644530-5643166 (Counterclockwise)

Preceding gene: 146342306

Following gene: 146342302

Centisome position: 75.7

GC content: 70.04

Gene sequence:

>1365_bases
ATGTGGCAGAATTGGTCGTTGCGCAGGCGCATCAACGTGCTGCTCGCGCTGGTGCTGACGCTGGGGCTCGCGCTCAATAT
CGGCCGGCTGGTGCTGGAGGCGGCGCCGCGCGTGCTCGCCGAGGACCAGAGCGTCATCCGCCTGACCCGCGCCTTCATCG
AGACCATCATGGACGAGGTCAACGACGCGCCGGATCCGGATTCCCGGTTGAACCGCATCGTCAGCGATCTCGGCCAGCTG
CGCCATGTCAGCGTGGCGAGGCAGGGGGCGGCGGTGCAGTTGCCGTCCTCGCAAGGCGCGGCGCGGGCGGCGCCGGCCTG
GTTCATCGCGCTGGTTCACCCGGACAAGACCTCGGTCAGCATGCCCGTGATCGTCGCAGGACGGGCCGACACGCTGGTGA
TCACCTCGCATCCCGACGACGAGATCGCCGAGATCTGGGACGGCATCGTCACGCAGCTGGTGGTCGGCTCCCTGGTCGGT
CTGGCGCTGTTCGGAATCACCACGCTGGTGGTCGGCCGCGCGCTGGCGCCGCTGTCGGATCTGTCCGACGCGATGAGCCG
TATCGAGACCGGCGCCTACGATGCCCGCGTCAAGCCGGGCGGCGCGCCCGAGCTCGCCGCGCTCTGCGCCAAGCTCAACC
ATCTCGCCGCCGCGCTCGGCGAGGCGGTAGAGGACAAGCGGCGGCTCGCCGAGCGGACAGTGTCGCTGCAAGACCTCGAG
CGCAAGGAAATCGCGCGCGAGCTGCATGACGAGTTCGGCCCGCATCTGTTCGCGCTGCGCGCCCATGCCAGCGCGCTGAT
GCGATTGCCGGAGGCGGACAGGCTGGACGTCGGTGCGATGCGCCGCCACGGCCAGGCGATCCTCGACCAAGTCAATGCCG
TGCAGCAATTCAATCGCCGCATCCTGGAGCGGCTGCGCCCGATCGGTCTGGCCGAGCTCGGCCTGCGCGAGGCGCTTGGC
GCGCTGGTGCGGCTCTGGCGGGAGTCGCGGCCGGAGGTGGTGATAGCGACCAGCTTCACCGACGAGGTCGCGCACGGCAA
CGAGACCGCCGAGCTGACGATCTATCGCGTCGTGCAGGAGGCTCTGACGAACGTGTTCCGCCATGCCGAGGCGACCTCGA
TCGATGTCAGCATCGAGCCGCTGCAGCAGACCGGCTCCGGCCAGCGCCGCAGCTACACACGGGTGCGCGTGCGCGACGAC
GGCCGCGGCCTCAAGCCCGAGCACAAGCTCGGCTTCGGCCTCACCGGCATGCGCGAGCGGCTGCTGGCGCTCGGCGGCAC
GCTGACCGTGACATCGAGCGGCACGGGGGTCACGATCGAGGCCATGGTGCCGGCGGATGCCACGGTGCCGGCTGACGCGG
CGTGA

Upstream 100 bases:

>100_bases
CGCCGGCGGATTTGTCTGTCAATGAATGCGCGCGTGAAACAACTCAGTGAAACAGCTGAGTGAAACAGCTGAGTAAAACT
GGGGCCTCGGGACGGTGACA

Downstream 100 bases:

>100_bases
GTTCACGGCGAGGAACATTCAACCTCGGAGCGCATTCATCGGTCATCCTGGTGATCCCCGCGTGCGCCGCAGTCCGGAGC
ACGCGCAGATAGCTCGCGGT

Product: putative two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MWQNWSLRRRINVLLALVLTLGLALNIGRLVLEAAPRVLAEDQSVIRLTRAFIETIMDEVNDAPDPDSRLNRIVSDLGQL
RHVSVARQGAAVQLPSSQGAARAAPAWFIALVHPDKTSVSMPVIVAGRADTLVITSHPDDEIAEIWDGIVTQLVVGSLVG
LALFGITTLVVGRALAPLSDLSDAMSRIETGAYDARVKPGGAPELAALCAKLNHLAAALGEAVEDKRRLAERTVSLQDLE
RKEIARELHDEFGPHLFALRAHASALMRLPEADRLDVGAMRRHGQAILDQVNAVQQFNRRILERLRPIGLAELGLREALG
ALVRLWRESRPEVVIATSFTDEVAHGNETAELTIYRVVQEALTNVFRHAEATSIDVSIEPLQQTGSGQRRSYTRVRVRDD
GRGLKPEHKLGFGLTGMRERLLALGGTLTVTSSGTGVTIEAMVPADATVPADAA

Sequences:

>Translated_454_residues
MWQNWSLRRRINVLLALVLTLGLALNIGRLVLEAAPRVLAEDQSVIRLTRAFIETIMDEVNDAPDPDSRLNRIVSDLGQL
RHVSVARQGAAVQLPSSQGAARAAPAWFIALVHPDKTSVSMPVIVAGRADTLVITSHPDDEIAEIWDGIVTQLVVGSLVG
LALFGITTLVVGRALAPLSDLSDAMSRIETGAYDARVKPGGAPELAALCAKLNHLAAALGEAVEDKRRLAERTVSLQDLE
RKEIARELHDEFGPHLFALRAHASALMRLPEADRLDVGAMRRHGQAILDQVNAVQQFNRRILERLRPIGLAELGLREALG
ALVRLWRESRPEVVIATSFTDEVAHGNETAELTIYRVVQEALTNVFRHAEATSIDVSIEPLQQTGSGQRRSYTRVRVRDD
GRGLKPEHKLGFGLTGMRERLLALGGTLTVTSSGTGVTIEAMVPADATVPADAA
>Mature_454_residues
MWQNWSLRRRINVLLALVLTLGLALNIGRLVLEAAPRVLAEDQSVIRLTRAFIETIMDEVNDAPDPDSRLNRIVSDLGQL
RHVSVARQGAAVQLPSSQGAARAAPAWFIALVHPDKTSVSMPVIVAGRADTLVITSHPDDEIAEIWDGIVTQLVVGSLVG
LALFGITTLVVGRALAPLSDLSDAMSRIETGAYDARVKPGGAPELAALCAKLNHLAAALGEAVEDKRRLAERTVSLQDLE
RKEIARELHDEFGPHLFALRAHASALMRLPEADRLDVGAMRRHGQAILDQVNAVQQFNRRILERLRPIGLAELGLREALG
ALVRLWRESRPEVVIATSFTDEVAHGNETAELTIYRVVQEALTNVFRHAEATSIDVSIEPLQQTGSGQRRSYTRVRVRDD
GRGLKPEHKLGFGLTGMRERLLALGGTLTVTSSGTGVTIEAMVPADATVPADAA

Specific function: Member of the two-component regulatory system moxY/moxX probably involved in the regulation of the methanol dehydrogenase expression. May function as a membrane-associated protein kinase that phosphorylates moxX in response to environmental signals [H]

COG id: COG3851

COG function: function code T; Signal transduction histidine kinase, glucose-6-phosphate specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=238, Percent_Identity=34.8739495798319, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR011712 [H]

Pfam domain/function: PF00672 HAMP; PF07730 HisKA_3 [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 49235; Mature: 49235

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWQNWSLRRRINVLLALVLTLGLALNIGRLVLEAAPRVLAEDQSVIRLTRAFIETIMDEV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
NDAPDPDSRLNRIVSDLGQLRHVSVARQGAAVQLPSSQGAARAAPAWFIALVHPDKTSVS
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCEEEEEEECCCCCCCC
MPVIVAGRADTLVITSHPDDEIAEIWDGIVTQLVVGSLVGLALFGITTLVVGRALAPLSD
CCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LSDAMSRIETGAYDARVKPGGAPELAALCAKLNHLAAALGEAVEDKRRLAERTVSLQDLE
HHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
RKEIARELHDEFGPHLFALRAHASALMRLPEADRLDVGAMRRHGQAILDQVNAVQQFNRR
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ILERLRPIGLAELGLREALGALVRLWRESRPEVVIATSFTDEVAHGNETAELTIYRVVQE
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHCCCCCHHHHHHHHHHH
ALTNVFRHAEATSIDVSIEPLQQTGSGQRRSYTRVRVRDDGRGLKPEHKLGFGLTGMRER
HHHHHHHHCCCCEEEEEEHHHHHCCCCCCCCEEEEEEECCCCCCCCCHHCCCCCHHHHHH
LLALGGTLTVTSSGTGVTIEAMVPADATVPADAA
HHHHCCCEEEECCCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MWQNWSLRRRINVLLALVLTLGLALNIGRLVLEAAPRVLAEDQSVIRLTRAFIETIMDEV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
NDAPDPDSRLNRIVSDLGQLRHVSVARQGAAVQLPSSQGAARAAPAWFIALVHPDKTSVS
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCEEEEEEECCCCCCCC
MPVIVAGRADTLVITSHPDDEIAEIWDGIVTQLVVGSLVGLALFGITTLVVGRALAPLSD
CCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LSDAMSRIETGAYDARVKPGGAPELAALCAKLNHLAAALGEAVEDKRRLAERTVSLQDLE
HHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
RKEIARELHDEFGPHLFALRAHASALMRLPEADRLDVGAMRRHGQAILDQVNAVQQFNRR
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ILERLRPIGLAELGLREALGALVRLWRESRPEVVIATSFTDEVAHGNETAELTIYRVVQE
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHCCCCCHHHHHHHHHHH
ALTNVFRHAEATSIDVSIEPLQQTGSGQRRSYTRVRVRDDGRGLKPEHKLGFGLTGMRER
HHHHHHHHCCCCEEEEEEHHHHHCCCCCCCCEEEEEEECCCCCCCCCHHCCCCCHHHHHH
LLALGGTLTVTSSGTGVTIEAMVPADATVPADAA
HHHHCCCEEEECCCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with a nitrogenous group as acceptor [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8392137 [H]