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The map label for this gene is oxc [H]

Identifier: 146341826

GI number: 146341826

Start: 5146275

End: 5148005

Strand: Direct

Name: oxc [H]

Synonym: BRADO4955

Alternate gene names: 146341826

Gene position: 5146275-5148005 (Clockwise)

Preceding gene: 146341825

Following gene: 146341827

Centisome position: 69.02

GC content: 66.32

Gene sequence:

>1731_bases
ATGCCGCAGACAGCCATGAAGACCGAGGTGGAAACCCACGAGGAGCTGACGGACGGCTTTCATCTCGTCATCGACGCGAT
GAAGCTGAACGGGATCGACACGATCTACAACGTTCCGGGGATTCCGATCACCGATCTCGGCCGCATGGCGCAGGCTGAAG
GCATCCGCGTGCTCTCCTTCCGTCACGAGCAGAACGCCGGCTACGCCGCCGCGATCGCCGGCTTCCTCACCAAGAAGCCG
GGCGTCTGCCTCACCGTGTCGGCGCCGGGCTTCCTCAACGGCCTCACCGCGCTGGCGCATGCCACCACCAACTGCTTCCC
GATGATCCTGGTCTCCGGCTCCTCGGAGCGCGAGATCGTCGACCTGCAGCAGGGCGACTACGAGGAGATGGACCAGCTCG
CGATCGCCAAGCCGCTGTGCAAGGCGGCGTTCCGCGTGCTGCACGCCCAGGACATCGGTATCGGCTTCGCGCGCGCCATC
CGCGCCGCCGTTTCGGGGCGTCCCGGCGGCGTCTACCTCGATCTACCGGCCAAGCTGTTCGGCCAGGTCATGAACGCGCA
GGCAGGCCACGCCTCGCTGGTGAAGGTGATCGATCCGGCGCCGGCGCAGATCCCCTCCCCCGACTCCGTCAAGCGCGCGC
TCGACGTGCTCAAGAGCGCCAAGCGCCCGCTGATCATCCTCGGCAAGGGCGCTGCCTATGCGCAGGCTGATGAAGCGATC
AAGACCTTCGTCGAGAAGAGCGGCGTGCCGTTCCTGCCGATGAGCATGGCCAAGGGCCTGCTGCCCGATCTGCATCCGCA
GTGCGCGGGCGCGGCGCGCTCGACGGTGCTGAAGGAGTCCGACGTCGTCATGCTGATCGGCGCCCGCCTCAACTGGCTGC
TGTCGCACGGCAAGGGCAAGAGCTGGGGCGATTCCCCGAAGAAGTTCATCCAGGTCGACATCGAGCCGAAGGAGATGGAT
TCCAACGTCGAGATCGCGGCCCCCGTGGTCGGCGACATCGGCTCGGTCGTCACGGCGTTCTCCGATGCGATGGGCAGCAG
CTGGACCAAGGCGCCGGTCGAGTGGCTGAGCGCGGTGCAGAAGAAGCGCGAGGACAACGTCGCCAAGATGGCGCCGCGGC
TGATGAACAACAACTCGCCGATGGACTATCACGGCGCGCTCGGCGTGCTCCGCACCATCATCAAGGAGCGCCCCGACGCG
ATCCTCGTCAACGAGGGCGCCAACACGCTCGACCTCGCCCGCGGCGTGATCGACATGTACCAGCCGCGCAAGCGGCTCGA
CGTCGGCACCTGGGGCGTGATGGGCATCGGCATGGGCTCGGCGATCGCCGCCGCCGTCGAGACCGGCAAGCCGGTGCTGG
CGATCGAGGGCGACTCGGCCTTCGGCTTCTCCGGCATGGAAGTCGAGACCATCTGCCGCTACAATCTGCCGATCTGCGTC
GTCATCTTCAACAATGACGGCATCTATCGCGGCACCGACCAGAACGCGGCGGGCTCTGATCCGGCGACCACCGTGTTCGT
CAAGGGCGCGCGCTACGACAAGATGATGGAGGCCTTCGGCGGCGTCGGCGTCAACGCGACTTCGCCGGATGAGCTGAAGC
GCGCCGTCAACGAGGCGATGGATTCCGGCAAGCCGACCCTGATCAACGCTGTGATCGATCCCGCCGCGGGCTCGGAGAGC
GGCCGCATCGGCAACCTCAATCCGCAGAGCGTGCTGACGAAGAAGAAGTAA

Upstream 100 bases:

>100_bases
TATGTCGAGACGCACGGCCAGGAACTATTCAGCTAGCTATTCAGCTAACTTCAAACAGAAGACGCGGAATGCGCCTTCAT
AGACGACCAGGGAGAGGCGC

Downstream 100 bases:

>100_bases
GGCCACCCACATCACCTGCCCGCGTGATGCGGGATGACCATTCGTTACGGAGAGGAACAACATGACCAAGGCGCTCGAGG
GCGTTCGCATTCTCGACTTC

Product: putative oxalyl-CoA decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 576; Mature: 575

Protein sequence:

>576_residues
MPQTAMKTEVETHEELTDGFHLVIDAMKLNGIDTIYNVPGIPITDLGRMAQAEGIRVLSFRHEQNAGYAAAIAGFLTKKP
GVCLTVSAPGFLNGLTALAHATTNCFPMILVSGSSEREIVDLQQGDYEEMDQLAIAKPLCKAAFRVLHAQDIGIGFARAI
RAAVSGRPGGVYLDLPAKLFGQVMNAQAGHASLVKVIDPAPAQIPSPDSVKRALDVLKSAKRPLIILGKGAAYAQADEAI
KTFVEKSGVPFLPMSMAKGLLPDLHPQCAGAARSTVLKESDVVMLIGARLNWLLSHGKGKSWGDSPKKFIQVDIEPKEMD
SNVEIAAPVVGDIGSVVTAFSDAMGSSWTKAPVEWLSAVQKKREDNVAKMAPRLMNNNSPMDYHGALGVLRTIIKERPDA
ILVNEGANTLDLARGVIDMYQPRKRLDVGTWGVMGIGMGSAIAAAVETGKPVLAIEGDSAFGFSGMEVETICRYNLPICV
VIFNNDGIYRGTDQNAAGSDPATTVFVKGARYDKMMEAFGGVGVNATSPDELKRAVNEAMDSGKPTLINAVIDPAAGSES
GRIGNLNPQSVLTKKK

Sequences:

>Translated_576_residues
MPQTAMKTEVETHEELTDGFHLVIDAMKLNGIDTIYNVPGIPITDLGRMAQAEGIRVLSFRHEQNAGYAAAIAGFLTKKP
GVCLTVSAPGFLNGLTALAHATTNCFPMILVSGSSEREIVDLQQGDYEEMDQLAIAKPLCKAAFRVLHAQDIGIGFARAI
RAAVSGRPGGVYLDLPAKLFGQVMNAQAGHASLVKVIDPAPAQIPSPDSVKRALDVLKSAKRPLIILGKGAAYAQADEAI
KTFVEKSGVPFLPMSMAKGLLPDLHPQCAGAARSTVLKESDVVMLIGARLNWLLSHGKGKSWGDSPKKFIQVDIEPKEMD
SNVEIAAPVVGDIGSVVTAFSDAMGSSWTKAPVEWLSAVQKKREDNVAKMAPRLMNNNSPMDYHGALGVLRTIIKERPDA
ILVNEGANTLDLARGVIDMYQPRKRLDVGTWGVMGIGMGSAIAAAVETGKPVLAIEGDSAFGFSGMEVETICRYNLPICV
VIFNNDGIYRGTDQNAAGSDPATTVFVKGARYDKMMEAFGGVGVNATSPDELKRAVNEAMDSGKPTLINAVIDPAAGSES
GRIGNLNPQSVLTKKK
>Mature_575_residues
PQTAMKTEVETHEELTDGFHLVIDAMKLNGIDTIYNVPGIPITDLGRMAQAEGIRVLSFRHEQNAGYAAAIAGFLTKKPG
VCLTVSAPGFLNGLTALAHATTNCFPMILVSGSSEREIVDLQQGDYEEMDQLAIAKPLCKAAFRVLHAQDIGIGFARAIR
AAVSGRPGGVYLDLPAKLFGQVMNAQAGHASLVKVIDPAPAQIPSPDSVKRALDVLKSAKRPLIILGKGAAYAQADEAIK
TFVEKSGVPFLPMSMAKGLLPDLHPQCAGAARSTVLKESDVVMLIGARLNWLLSHGKGKSWGDSPKKFIQVDIEPKEMDS
NVEIAAPVVGDIGSVVTAFSDAMGSSWTKAPVEWLSAVQKKREDNVAKMAPRLMNNNSPMDYHGALGVLRTIIKERPDAI
LVNEGANTLDLARGVIDMYQPRKRLDVGTWGVMGIGMGSAIAAAVETGKPVLAIEGDSAFGFSGMEVETICRYNLPICVV
IFNNDGIYRGTDQNAAGSDPATTVFVKGARYDKMMEAFGGVGVNATSPDELKRAVNEAMDSGKPTLINAVIDPAAGSESG
RIGNLNPQSVLTKKK

Specific function: Oxalic acid catabolism; second step. [C]

COG id: COG0028

COG function: function code EH; Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TPP enzyme family [H]

Homologues:

Organism=Homo sapiens, GI93004078, Length=565, Percent_Identity=39.1150442477876, Blast_Score=409, Evalue=1e-114,
Organism=Homo sapiens, GI21361361, Length=570, Percent_Identity=27.1929824561404, Blast_Score=181, Evalue=2e-45,
Organism=Escherichia coli, GI1788716, Length=559, Percent_Identity=60.1073345259392, Blast_Score=667, Evalue=0.0,
Organism=Escherichia coli, GI87081685, Length=565, Percent_Identity=24.070796460177, Blast_Score=163, Evalue=3e-41,
Organism=Escherichia coli, GI1790104, Length=549, Percent_Identity=25.3187613843352, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1786717, Length=555, Percent_Identity=25.9459459459459, Blast_Score=128, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17531299, Length=551, Percent_Identity=38.2940108892922, Blast_Score=363, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17531301, Length=551, Percent_Identity=38.2940108892922, Blast_Score=363, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17542570, Length=592, Percent_Identity=26.8581081081081, Blast_Score=198, Evalue=5e-51,
Organism=Saccharomyces cerevisiae, GI6320816, Length=541, Percent_Identity=34.1959334565619, Blast_Score=281, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6323755, Length=579, Percent_Identity=21.7616580310881, Blast_Score=110, Evalue=7e-25,
Organism=Drosophila melanogaster, GI19922626, Length=562, Percent_Identity=38.9679715302491, Blast_Score=399, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017660
- InterPro:   IPR012000
- InterPro:   IPR012001
- InterPro:   IPR011766 [H]

Pfam domain/function: PF02775 TPP_enzyme_C; PF00205 TPP_enzyme_M; PF02776 TPP_enzyme_N [H]

EC number: =4.1.1.8 [H]

Molecular weight: Translated: 61189; Mature: 61058

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQTAMKTEVETHEELTDGFHLVIDAMKLNGIDTIYNVPGIPITDLGRMAQAEGIRVLSF
CCCCHHHHHHHHHHHHHCCCEEEEEHHHHCCCCHHHCCCCCCHHHHHHHHHHCCEEEEEE
RHEQNAGYAAAIAGFLTKKPGVCLTVSAPGFLNGLTALAHATTNCFPMILVSGSSEREIV
EECCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCEEE
DLQQGDYEEMDQLAIAKPLCKAAFRVLHAQDIGIGFARAIRAAVSGRPGGVYLDLPAKLF
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEECCHHHH
GQVMNAQAGHASLVKVIDPAPAQIPSPDSVKRALDVLKSAKRPLIILGKGAAYAQADEAI
HHHHCCCCCCHHHHEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHH
KTFVEKSGVPFLPMSMAKGLLPDLHPQCAGAARSTVLKESDVVMLIGARLNWLLSHGKGK
HHHHHHCCCCEECHHHHHCCCCCCCHHHCCHHHHHHCCCCCEEEEECCHHHHHHHCCCCC
SWGDSPKKFIQVDIEPKEMDSNVEIAAPVVGDIGSVVTAFSDAMGSSWTKAPVEWLSAVQ
CCCCCCCCEEEEECCHHHCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
KKREDNVAKMAPRLMNNNSPMDYHGALGVLRTIIKERPDAILVNEGANTLDLARGVIDMY
HHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHH
QPRKRLDVGTWGVMGIGMGSAIAAAVETGKPVLAIEGDSAFGFSGMEVETICRYNLPICV
CCHHHCCCCCCCHHHCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHEECCCCEEE
VIFNNDGIYRGTDQNAAGSDPATTVFVKGARYDKMMEAFGGVGVNATSPDELKRAVNEAM
EEECCCCEEECCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
DSGKPTLINAVIDPAAGSESGRIGNLNPQSVLTKKK
HCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHCCCC
>Mature Secondary Structure 
PQTAMKTEVETHEELTDGFHLVIDAMKLNGIDTIYNVPGIPITDLGRMAQAEGIRVLSF
CCCHHHHHHHHHHHHHCCCEEEEEHHHHCCCCHHHCCCCCCHHHHHHHHHHCCEEEEEE
RHEQNAGYAAAIAGFLTKKPGVCLTVSAPGFLNGLTALAHATTNCFPMILVSGSSEREIV
EECCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCEEE
DLQQGDYEEMDQLAIAKPLCKAAFRVLHAQDIGIGFARAIRAAVSGRPGGVYLDLPAKLF
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEECCHHHH
GQVMNAQAGHASLVKVIDPAPAQIPSPDSVKRALDVLKSAKRPLIILGKGAAYAQADEAI
HHHHCCCCCCHHHHEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHH
KTFVEKSGVPFLPMSMAKGLLPDLHPQCAGAARSTVLKESDVVMLIGARLNWLLSHGKGK
HHHHHHCCCCEECHHHHHCCCCCCCHHHCCHHHHHHCCCCCEEEEECCHHHHHHHCCCCC
SWGDSPKKFIQVDIEPKEMDSNVEIAAPVVGDIGSVVTAFSDAMGSSWTKAPVEWLSAVQ
CCCCCCCCEEEEECCHHHCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
KKREDNVAKMAPRLMNNNSPMDYHGALGVLRTIIKERPDAILVNEGANTLDLARGVIDMY
HHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHH
QPRKRLDVGTWGVMGIGMGSAIAAAVETGKPVLAIEGDSAFGFSGMEVETICRYNLPICV
CCHHHCCCCCCCHHHCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHEECCCCEEE
VIFNNDGIYRGTDQNAAGSDPATTVFVKGARYDKMMEAFGGVGVNATSPDELKRAVNEAM
EEECCCCEEECCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
DSGKPTLINAVIDPAAGSESGRIGNLNPQSVLTKKK
HCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157618 [H]