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The map label for this gene is bcpC [H]

Identifier: 146341805

GI number: 146341805

Start: 5124344

End: 5124943

Strand: Direct

Name: bcpC [H]

Synonym: BRADO4925

Alternate gene names: 146341805

Gene position: 5124344-5124943 (Clockwise)

Preceding gene: 146341804

Following gene: 146341806

Centisome position: 68.72

GC content: 66.17

Gene sequence:

>600_bases
ATGACCGCCGCCATCAGCAACACCAAGATCATGAACCGCCACGATCTCACCTGCCGGCTGGTCGCCAAGCTGACGCGCGA
GGAGGCCGTGATCGGCGGCATCGGCAACACCAATTTCGATCTGTGGGCGGCGGGCCCGCGGCCGCAGAACTTCTACATGC
TCGGCAGCATGGGACTGGCCTGCCCGATCGCGCTCGGCGTCGCGCTGGCGCAGCCGCAGCGCCGCGTGTTCGCGCTCGAA
GGCGACGGCTCGCTGCTGATGCAATTGGGCTGCCTGACCACGATCGCGTCGCTGGCGCTGAGCAACCTGACTATCATCGT
GATGGACAACGGCATCTACCAGATCACCGGCAGCCAGCCGACACCGGCCAAGCAGGCCGATATCGTCGCCATTGCTGCTG
GCTGCGGCATCGTGTCCAGCCATTGGGCGGCCGACGAGGCGGACTTCGAACGGCTGGTCGATGCTGCGCTCGAGCTGCCA
GGCCCGATGCTGATCGCGGTCAAGATCGACGACAAACCGGGCGTCGGCGCCACCCACCGCGATCCGGCGCAGATCCGCGA
GCGCTTCATGCAGGGCCTCGGCGTCAGAATACCGATTTGA

Upstream 100 bases:

>100_bases
TCGAATTCATCGTCGACCGCTCGATCAAACAGGCGGTGGCGACGCAGGCCCCGGTGGCGCTGATCCTGTCGCCGCTGCTC
ACGGGCGGAAAGGTGTTCGC

Downstream 100 bases:

>100_bases
AGATCCTGCGACATCCGCGCGCTACCCCGCCTGGGGCCACGAAATGTCATGAAGCAGCCCGCTTGATCACGCTAGATAGG
TGCTTCATCACCCGCACCGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MTAAISNTKIMNRHDLTCRLVAKLTREEAVIGGIGNTNFDLWAAGPRPQNFYMLGSMGLACPIALGVALAQPQRRVFALE
GDGSLLMQLGCLTTIASLALSNLTIIVMDNGIYQITGSQPTPAKQADIVAIAAGCGIVSSHWAADEADFERLVDAALELP
GPMLIAVKIDDKPGVGATHRDPAQIRERFMQGLGVRIPI

Sequences:

>Translated_199_residues
MTAAISNTKIMNRHDLTCRLVAKLTREEAVIGGIGNTNFDLWAAGPRPQNFYMLGSMGLACPIALGVALAQPQRRVFALE
GDGSLLMQLGCLTTIASLALSNLTIIVMDNGIYQITGSQPTPAKQADIVAIAAGCGIVSSHWAADEADFERLVDAALELP
GPMLIAVKIDDKPGVGATHRDPAQIRERFMQGLGVRIPI
>Mature_198_residues
TAAISNTKIMNRHDLTCRLVAKLTREEAVIGGIGNTNFDLWAAGPRPQNFYMLGSMGLACPIALGVALAQPQRRVFALEG
DGSLLMQLGCLTTIASLALSNLTIIVMDNGIYQITGSQPTPAKQADIVAIAAGCGIVSSHWAADEADFERLVDAALELPG
PMLIAVKIDDKPGVGATHRDPAQIRERFMQGLGVRIPI

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0028

COG function: function code EH; Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TPP enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1790104, Length=134, Percent_Identity=33.5820895522388, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017684
- InterPro:   IPR012001
- InterPro:   IPR011766 [H]

Pfam domain/function: PF02775 TPP_enzyme_C; PF02776 TPP_enzyme_N [H]

EC number: =4.1.1.82 [H]

Molecular weight: Translated: 21120; Mature: 20989

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00187 TPP_ENZYMES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAISNTKIMNRHDLTCRLVAKLTREEAVIGGIGNTNFDLWAAGPRPQNFYMLGSMGLA
CCCCCCCCEECCCCCCHHHHHHHHHHHHEEEECCCCCCEEEEECCCCCCCEEEECCCCCH
CPIALGVALAQPQRRVFALEGDGSLLMQLGCLTTIASLALSNLTIIVMDNGIYQITGSQP
HHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEEEECCEEEEECCCC
TPAKQADIVAIAAGCGIVSSHWAADEADFERLVDAALELPGPMLIAVKIDDKPGVGATHR
CCCCCCCEEEEEECCCCHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCC
DPAQIRERFMQGLGVRIPI
CHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TAAISNTKIMNRHDLTCRLVAKLTREEAVIGGIGNTNFDLWAAGPRPQNFYMLGSMGLA
CCCCCCCEECCCCCCHHHHHHHHHHHHEEEECCCCCCEEEEECCCCCCCEEEECCCCCH
CPIALGVALAQPQRRVFALEGDGSLLMQLGCLTTIASLALSNLTIIVMDNGIYQITGSQP
HHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEEEECCEEEEECCCC
TPAKQADIVAIAAGCGIVSSHWAADEADFERLVDAALELPGPMLIAVKIDDKPGVGATHR
CCCCCCCEEEEEECCCCHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCC
DPAQIRERFMQGLGVRIPI
CHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10786631 [H]