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The map label for this gene is luxQ [H]

Identifier: 146341588

GI number: 146341588

Start: 4878722

End: 4880917

Strand: Reverse

Name: luxQ [H]

Synonym: BRADO4689

Alternate gene names: 146341588

Gene position: 4880917-4878722 (Counterclockwise)

Preceding gene: 146341589

Following gene: 146341587

Centisome position: 65.46

GC content: 64.39

Gene sequence:

>2196_bases
ATGCGCAGGCTGATATCCAAATCGATGCCGTTCTTCGGCCGGCTCGACCGGGCCGTCGATACGATGGTGCGGCTGATCGG
GCATTTCGGCAGCGCCGTGATCGGCCTGTCGGCGATCGCGCTGGTGTGGGCCGGGATCTTCTACACGATCACCGAGGAGC
ACTCCCGCACCGAGCAGTCGGCGCTCAAGAACGGCGCCAATCTCGCGCGCGCCTTCGAGGAGCAGATCATCCGCTCCATC
CGCGCCGCGGACCAGACGCTGCTTTATGTCCGCGACTCCTACGCCAAGGACCCGCAGAACTTCGACATGTCGTTGTGGTC
GAAGAACAGCCAGTTCCTGTCCGACTTCTCGTTCCAGGTGGTGGTGATCGGCAAGGACGGCATCATGCTGTCCAGCAACA
TCGACCCGAAGATGCGCGGCGTGGACCTGCGTGACCGCGAGCACTTCCGTGTCCATGCCGACGGCAAGGACGACTTTCTC
TTCATCAGCAAGCCGATCTTCGGCCGCGTCTCCAACAAATGGTCGATCCAGCTGACCCGCCGCATCATCATGCCCGACGG
CTCGTTCGGCGGCGTCGTGGTGGTCTCGCTCGACCCTGAATATCTCTCGAGCTTCTACAATTCGGTCGATCTCGGCAAGA
ACGGCAACGTCACCCTGGTGGGTCTTGACGGCATCGTGCGCGCGCGAGCCTCGGCGGGTCCCACCGGCGTCGGCTCCTCG
CTCGCCGGAAGTCCGGTCATGGCCGCGATCCAGCACAGGAGCAGCGGCTCCTACACCGTCAAGAGCCTGATCGACGGCAT
TCCGCGCATCTATTCGTTCCAACGCATCAAGGACCAGCCGCTGGTGGTCATCGTCGGCCAGGCGTCCGACGAGATCTTCG
CGGCCTTCAAGCGCAATCGCGATCGCGACCTGCTGGTCGGCGGGCTGCTGACCGTCGTGATCGGCATCATCACAATCCTG
ATCGCACGCTATCAGGCCGGCCTCGCCGCGTCGCGCGATGCCGCCGAGGCTGGCACCCGGGCGCGTTCGGAATTCCTGGC
GATGATGAGCCACGAGATCCGCACGCCCATGAACGGCGTCATTGGCCTTGCCGACCTGCTGCTGTCAGCCGACCTGGCGC
CGGAGCAGCGCAAGATCGCGACCACGCTGCGCGAGTCGGCCGACTATCTGCTGCAGCTTCTCAATGACGTGCTTGATTTC
TCCAAGCTGGATGCCGACCGGCTCGAGATCGAGCATATCGAGTTCGACCTCCACCGGTCGGTGACCGCGACCGCCGAGCT
CCTGGTCTCCCGCGCCAAGGAGAAGGGGCTGCAACTGACCACCTCGATCGCACCCGATGTGCCGACCTACGTGGTCGGCG
ATCCCGCACGGCTGCGGCAGGTGCTGTTCAACCTGGTCGGCAACGCGCTGAAATTCACCGAGGCGGGCAGCGTTCATGTC
GACGTCCGGGCCGAAGATCTCGCCGGGCCGAACCTGACGCTCGTGTTCTCGGTTGCCGACACCGGCGTCGGCATTCCGGC
GGAGGCAGTCGGGCGCCTGTTCAAGCAGTTCTCGCAGGTCGACAATTCGATCTCGCGCCGCTTCGGCGGCACGGGGCTCG
GACTTGCGATCTGCAAGCGTCTCGTCACCTGCATGGGCGGCGACATCAAGGTGCAGAGCAAGGTCGGCGAGGGCAGTACC
TTCACCTTCTCGATCCAGGTTCAGCCGCAACCTCAGCCGGACGTGGAGCAGGTGAGCGCACCCGAAGCCACCATCGCTCC
GGTCGGCGAGGCCGTCGTCGAGGAGCGTCCCGCGCCCGTCGAGCCGCTCAGGATCCTCGTCGCCGAGGACAATCTCACCA
ATCAGTTCGTGATCAAGAAGCTCCTCGACAAGCTCGGCCACAGCTATGAGCTCGTCGAGAACGGCACCCAGGCGGTGGCC
GCCGTGCAGAAGCAGACCTACGACCTGATCCTGATGGACATGATGATGCCGGAGATGGACGGCTTGACCGCGACGCGGAT
GATCCGCTCGCTGCCGCCACCCGCGCAGGACATCTACATCATTGCTCTGACGGCCAACGCCACCAGCCAGGATCATCTGG
CGTGCACGGATGCCGGCATGAACGACTTCGTGACCAAGCCGGTCACACGCGATCGACTGAACGCCGCTCTGCTCCGCGCG
GCCGCGGCCACGAACAAGGAAAGGCTTGTCGCATGA

Upstream 100 bases:

>100_bases
GAATGTTAAGGGGCTGTCGCCTGTTGAGAAGATTTTATCCATCAAGCTTTACCTGATGGCGAGCCTGCATCGCTAGGCAT
GACCTCCGAGGACGAGTGAC

Downstream 100 bases:

>100_bases
CCGACCTGGTGCAATTCGATGAATCCGTCTACCAGATCCTGATCTCCGAGCTCGGCGAGGAGGATGCCCTGGAGGTGCTC
AGGACCTTCCTGGACGACAC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 731; Mature: 731

Protein sequence:

>731_residues
MRRLISKSMPFFGRLDRAVDTMVRLIGHFGSAVIGLSAIALVWAGIFYTITEEHSRTEQSALKNGANLARAFEEQIIRSI
RAADQTLLYVRDSYAKDPQNFDMSLWSKNSQFLSDFSFQVVVIGKDGIMLSSNIDPKMRGVDLRDREHFRVHADGKDDFL
FISKPIFGRVSNKWSIQLTRRIIMPDGSFGGVVVVSLDPEYLSSFYNSVDLGKNGNVTLVGLDGIVRARASAGPTGVGSS
LAGSPVMAAIQHRSSGSYTVKSLIDGIPRIYSFQRIKDQPLVVIVGQASDEIFAAFKRNRDRDLLVGGLLTVVIGIITIL
IARYQAGLAASRDAAEAGTRARSEFLAMMSHEIRTPMNGVIGLADLLLSADLAPEQRKIATTLRESADYLLQLLNDVLDF
SKLDADRLEIEHIEFDLHRSVTATAELLVSRAKEKGLQLTTSIAPDVPTYVVGDPARLRQVLFNLVGNALKFTEAGSVHV
DVRAEDLAGPNLTLVFSVADTGVGIPAEAVGRLFKQFSQVDNSISRRFGGTGLGLAICKRLVTCMGGDIKVQSKVGEGST
FTFSIQVQPQPQPDVEQVSAPEATIAPVGEAVVEERPAPVEPLRILVAEDNLTNQFVIKKLLDKLGHSYELVENGTQAVA
AVQKQTYDLILMDMMMPEMDGLTATRMIRSLPPPAQDIYIIALTANATSQDHLACTDAGMNDFVTKPVTRDRLNAALLRA
AAATNKERLVA

Sequences:

>Translated_731_residues
MRRLISKSMPFFGRLDRAVDTMVRLIGHFGSAVIGLSAIALVWAGIFYTITEEHSRTEQSALKNGANLARAFEEQIIRSI
RAADQTLLYVRDSYAKDPQNFDMSLWSKNSQFLSDFSFQVVVIGKDGIMLSSNIDPKMRGVDLRDREHFRVHADGKDDFL
FISKPIFGRVSNKWSIQLTRRIIMPDGSFGGVVVVSLDPEYLSSFYNSVDLGKNGNVTLVGLDGIVRARASAGPTGVGSS
LAGSPVMAAIQHRSSGSYTVKSLIDGIPRIYSFQRIKDQPLVVIVGQASDEIFAAFKRNRDRDLLVGGLLTVVIGIITIL
IARYQAGLAASRDAAEAGTRARSEFLAMMSHEIRTPMNGVIGLADLLLSADLAPEQRKIATTLRESADYLLQLLNDVLDF
SKLDADRLEIEHIEFDLHRSVTATAELLVSRAKEKGLQLTTSIAPDVPTYVVGDPARLRQVLFNLVGNALKFTEAGSVHV
DVRAEDLAGPNLTLVFSVADTGVGIPAEAVGRLFKQFSQVDNSISRRFGGTGLGLAICKRLVTCMGGDIKVQSKVGEGST
FTFSIQVQPQPQPDVEQVSAPEATIAPVGEAVVEERPAPVEPLRILVAEDNLTNQFVIKKLLDKLGHSYELVENGTQAVA
AVQKQTYDLILMDMMMPEMDGLTATRMIRSLPPPAQDIYIIALTANATSQDHLACTDAGMNDFVTKPVTRDRLNAALLRA
AAATNKERLVA
>Mature_731_residues
MRRLISKSMPFFGRLDRAVDTMVRLIGHFGSAVIGLSAIALVWAGIFYTITEEHSRTEQSALKNGANLARAFEEQIIRSI
RAADQTLLYVRDSYAKDPQNFDMSLWSKNSQFLSDFSFQVVVIGKDGIMLSSNIDPKMRGVDLRDREHFRVHADGKDDFL
FISKPIFGRVSNKWSIQLTRRIIMPDGSFGGVVVVSLDPEYLSSFYNSVDLGKNGNVTLVGLDGIVRARASAGPTGVGSS
LAGSPVMAAIQHRSSGSYTVKSLIDGIPRIYSFQRIKDQPLVVIVGQASDEIFAAFKRNRDRDLLVGGLLTVVIGIITIL
IARYQAGLAASRDAAEAGTRARSEFLAMMSHEIRTPMNGVIGLADLLLSADLAPEQRKIATTLRESADYLLQLLNDVLDF
SKLDADRLEIEHIEFDLHRSVTATAELLVSRAKEKGLQLTTSIAPDVPTYVVGDPARLRQVLFNLVGNALKFTEAGSVHV
DVRAEDLAGPNLTLVFSVADTGVGIPAEAVGRLFKQFSQVDNSISRRFGGTGLGLAICKRLVTCMGGDIKVQSKVGEGST
FTFSIQVQPQPQPDVEQVSAPEATIAPVGEAVVEERPAPVEPLRILVAEDNLTNQFVIKKLLDKLGHSYELVENGTQAVA
AVQKQTYDLILMDMMMPEMDGLTATRMIRSLPPPAQDIYIIALTANATSQDHLACTDAGMNDFVTKPVTRDRLNAALLRA
AAATNKERLVA

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=398, Percent_Identity=38.4422110552764, Blast_Score=235, Evalue=8e-63,
Organism=Escherichia coli, GI48994928, Length=396, Percent_Identity=34.0909090909091, Blast_Score=222, Evalue=5e-59,
Organism=Escherichia coli, GI1788713, Length=396, Percent_Identity=34.8484848484849, Blast_Score=196, Evalue=6e-51,
Organism=Escherichia coli, GI145693157, Length=270, Percent_Identity=42.2222222222222, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI87081816, Length=422, Percent_Identity=30.5687203791469, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1786600, Length=255, Percent_Identity=30.9803921568627, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1790436, Length=302, Percent_Identity=27.4834437086093, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1786912, Length=261, Percent_Identity=27.2030651340996, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786783, Length=227, Percent_Identity=30.8370044052863, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788393, Length=217, Percent_Identity=29.9539170506912, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87082128, Length=230, Percent_Identity=28.2608695652174, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788549, Length=227, Percent_Identity=24.2290748898678, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1790437, Length=121, Percent_Identity=32.2314049586777, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790300, Length=216, Percent_Identity=31.9444444444444, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787894, Length=235, Percent_Identity=26.8085106382979, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790551, Length=214, Percent_Identity=31.7757009345794, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1790346, Length=225, Percent_Identity=29.3333333333333, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=117, Percent_Identity=38.4615384615385, Blast_Score=88, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6322044, Length=130, Percent_Identity=38.4615384615385, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 79616; Mature: 79616

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLISKSMPFFGRLDRAVDTMVRLIGHFGSAVIGLSAIALVWAGIFYTITEEHSRTEQS
CCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHH
ALKNGANLARAFEEQIIRSIRAADQTLLYVRDSYAKDPQNFDMSLWSKNSQFLSDFSFQV
HHHCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHCCCHHHHCCCCEEE
VVIGKDGIMLSSNIDPKMRGVDLRDREHFRVHADGKDDFLFISKPIFGRVSNKWSIQLTR
EEEECCCEEEECCCCCCCCCCCCCCCCCEEEEECCCCCEEEECCCHHCCCCCCEEEEEEE
RIIMPDGSFGGVVVVSLDPEYLSSFYNSVDLGKNGNVTLVGLDGIVRARASAGPTGVGSS
EEEECCCCCCCEEEEEECHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHCCCCCCCCCCC
LAGSPVMAAIQHRSSGSYTVKSLIDGIPRIYSFQRIKDQPLVVIVGQASDEIFAAFKRNR
CCCCHHHHHHHHCCCCCEEHHHHHCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCC
DRDLLVGGLLTVVIGIITILIARYQAGLAASRDAAEAGTRARSEFLAMMSHEIRTPMNGV
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
IGLADLLLSADLAPEQRKIATTLRESADYLLQLLNDVLDFSKLDADRLEIEHIEFDLHRS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEEEEHHHHH
VTATAELLVSRAKEKGLQLTTSIAPDVPTYVVGDPARLRQVLFNLVGNALKFTEAGSVHV
HHHHHHHHHHHHHHCCCEEEECCCCCCCCEEECCHHHHHHHHHHHHCCCEEECCCCCEEE
DVRAEDLAGPNLTLVFSVADTGVGIPAEAVGRLFKQFSQVDNSISRRFGGTGLGLAICKR
EEEHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LVTCMGGDIKVQSKVGEGSTFTFSIQVQPQPQPDVEQVSAPEATIAPVGEAVVEERPAPV
HHHHCCCCEEEEEECCCCCEEEEEEEECCCCCCCHHHCCCCCCHHHHCCHHHHHCCCCCC
EPLRILVAEDNLTNQFVIKKLLDKLGHSYELVENGTQAVAAVQKQTYDLILMDMMMPEMD
CCEEEEEECCCCCHHHHHHHHHHHCCCCEEHHHCCHHHHHHHHHHHHHHHHHHHHCCCCC
GLTATRMIRSLPPPAQDIYIIALTANATSQDHLACTDAGMNDFVTKPVTRDRLNAALLRA
CHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCEEEECCCCHHHHCCCCCHHHHHHHHHHH
AAATNKERLVA
HHHCCCHHCCC
>Mature Secondary Structure
MRRLISKSMPFFGRLDRAVDTMVRLIGHFGSAVIGLSAIALVWAGIFYTITEEHSRTEQS
CCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHH
ALKNGANLARAFEEQIIRSIRAADQTLLYVRDSYAKDPQNFDMSLWSKNSQFLSDFSFQV
HHHCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHCCCHHHHCCCCEEE
VVIGKDGIMLSSNIDPKMRGVDLRDREHFRVHADGKDDFLFISKPIFGRVSNKWSIQLTR
EEEECCCEEEECCCCCCCCCCCCCCCCCEEEEECCCCCEEEECCCHHCCCCCCEEEEEEE
RIIMPDGSFGGVVVVSLDPEYLSSFYNSVDLGKNGNVTLVGLDGIVRARASAGPTGVGSS
EEEECCCCCCCEEEEEECHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHCCCCCCCCCCC
LAGSPVMAAIQHRSSGSYTVKSLIDGIPRIYSFQRIKDQPLVVIVGQASDEIFAAFKRNR
CCCCHHHHHHHHCCCCCEEHHHHHCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCC
DRDLLVGGLLTVVIGIITILIARYQAGLAASRDAAEAGTRARSEFLAMMSHEIRTPMNGV
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
IGLADLLLSADLAPEQRKIATTLRESADYLLQLLNDVLDFSKLDADRLEIEHIEFDLHRS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEEEEHHHHH
VTATAELLVSRAKEKGLQLTTSIAPDVPTYVVGDPARLRQVLFNLVGNALKFTEAGSVHV
HHHHHHHHHHHHHHCCCEEEECCCCCCCCEEECCHHHHHHHHHHHHCCCEEECCCCCEEE
DVRAEDLAGPNLTLVFSVADTGVGIPAEAVGRLFKQFSQVDNSISRRFGGTGLGLAICKR
EEEHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LVTCMGGDIKVQSKVGEGSTFTFSIQVQPQPQPDVEQVSAPEATIAPVGEAVVEERPAPV
HHHHCCCCEEEEEECCCCCEEEEEEEECCCCCCCHHHCCCCCCHHHHCCHHHHHCCCCCC
EPLRILVAEDNLTNQFVIKKLLDKLGHSYELVENGTQAVAAVQKQTYDLILMDMMMPEMD
CCEEEEEECCCCCHHHHHHHHHHHCCCCEEHHHCCHHHHHHHHHHHHHHHHHHHHCCCCC
GLTATRMIRSLPPPAQDIYIIALTANATSQDHLACTDAGMNDFVTKPVTRDRLNAALLRA
CHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCEEEECCCCHHHHCCCCCHHHHHHHHHHH
AAATNKERLVA
HHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA