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The map label for this gene is nlpI [C]

Identifier: 146341560

GI number: 146341560

Start: 4849855

End: 4852083

Strand: Direct

Name: nlpI [C]

Synonym: BRADO4659

Alternate gene names: 146341560

Gene position: 4849855-4852083 (Clockwise)

Preceding gene: 146341559

Following gene: 146341562

Centisome position: 65.04

GC content: 66.8

Gene sequence:

>2229_bases
GTGCAAAGCAGCGTCGGCTCGCGGGCCTTTCAGAACGCGCGGCTCCAAAAGCGGGCCAAGAAGCAGGCGGATGTGCTGCT
GCCGGCGGCCGTGAAGGCCTATCGCGAGGGACGGCAGCATGAGGTTCAGGCGCTGTGCCAGCAGATCCTGCAGGATTTAC
CGCAGCATCTCGGGGCCCTGCATCTGCTTGGCGTGTCCGAACGGGATTGCGGCCATTTCGATCAGGCCGTGCTGCTGCTG
ACGCGCGCCGTCGAGATCGATCCGCGCTCGGCCGATGTCCAGTCCGATCTCGGCCTGGCGCTGTCCCGGCTCGGCCGGCA
TGAGGAGGCCCGGGTCCGCTTCGAGCGCGCCATCGCGCTGAAGCCGAACTTCCCCTCCGCGTTCACGCATCTCGGCAACG
CGCTGATGAGCCTGTTCCGTTTCGAGGAGGCGATCTCGGCGCATGACCGCGCCATTGCGCTGAAGCCCGACCACGCCGAG
GCCTACGCCAATCGCGGCATGGCGCTGATGTTCACGAGCCGCAACGGCGAGGCCGCCCAGAACTTCGATCGCGCGCTCTC
GCTGCAGCCGCGGCTGCTGACGGCCCTGTTCGGCAAGGGCGTGGCCAGCATGAACCTGCGGGATTTCGACGCCGCACTGG
CCGCCTTGAATGCGGCGCTGGCGATCAATCCGAAAGCGGCCGCCGTGATCGCCCAGCGCGGGCGGGCGTATCAGGAGCTG
GGCAGGTTCGCCGAGGCGGAATCCGATTTCGACGCCGCTCTCGCGCTCGAGCCTCTGCTGGAAGAAGCTCTTTGCGGCAA
GGCCGCGGTCACGCTGGTCGATGGCAACATCGCGCTTTCGATCTCGGTCATCAACAAGGTGCTGGCACAGAATCCGAACT
CGGAGATCGCCTGGACGCTGCTCGGCGTTTGCGCCGCGGCGCAGGGCGACACCGCCACCGCAATCGACCATTACGACCGC
GCGCTCGCGATCCGGCCGAACCATGAGGACGCGATCACCAAGAAGATCTTCGCGCTGGATTTCTTGCCCGACACCGGGGT
GGAACGTCTCCAGGAGGCGCGGAGATATTGGTGGGAGGCGATCGGCTCGCGCCTGGAACGCCGCTCGCTCGGCGTGCGAA
ACATCGACCCCGACCGGCGCCTCGTCGTCGGCTACGTCTCGTCCGATTTCCGCGACCATTCGGCGGCCTTCGCCTTCCTG
CCCATCCTGCGCCATCACGACCGCGCAAAGTTCGAGGTTGTTGCGTATTCCTGCTCGCCGATGAAGGACGCCAAGACCGA
GCTGTGCCGCTCGCTTGTCGATCGCTTCGTCGACGCCTCGCTGTGGGGCGACGACAAGCTCGCCGATCAGATCCAGGCCG
ACAAGGTCGACATCCTCGTCGACCTCTCCGGGCATTCCGCCGGTCACCGGCTCACCATGTTTGCGCGCAAGCCGGCGCCG
ATCCAGGTCTCGGCCGTCGGCAGCGTCACCGGGACGGGCCTGCCCGTCATGGATTATCTGCTGGCGGATCCGGTGGTGAT
CCCGGCCGCGGTCCGGCACCTGTTTGCCGAGACGATCTACGACCTGCCGTCGCTGATCACGATCGAGCCGCCGCCGCCTC
TTCCGCCATCGCCGCTCCCGATGCTGCGGAACGGCCATGTGACCTTCGGCGCGTTCAATCGCATCGACAAGATCTCCGAG
CCGACCGTCAAACTCTGGTCGCAACTGATGCAGGCGACGCCGGGCTCGATCATCGTGATCAAGAATCACTCGATGGGCGA
TCCCCTGCTGCGCGACCGATTGATCGCCCGCTTCGTCGCCCACGGCATCGCCGCGGACCGCGTCCGCTGTGTAGGCAAGA
CCACACGGCTCGAGCATCTTGCGATGTTCGCCGAGATCGACATCTCGCTCGATCCGTTCCCGCAGAATGGCGGCATCTCG
ACCTGGGAGTCGCTGCAGATGGGCGTGCCCGTGGTCACCAAGCTCGGCAGCGGCCCCGCGGCCCGCGCGGGCGGCGCTAT
CGTCAAGGCGGTCGGCCTCGACGAATGGGTCGGTGAAGACGACGACGGCTATCTCGCGATCGCGCGGAGCTTCTGCTCGC
GGCCCGCGGAGCTTGCCGCGCTGCGCGCCGAGCTTCCGGCCATGGTCGCGCAGTCGGCTGCCGGAAACAACGCGCTCTAC
ACGCAGCAGGTCGAGACGGCCTACCGGACGTTCTGGCAGGACTATTGTCGGCACGCGCCGATCCGCTAG

Upstream 100 bases:

>100_bases
GCTCTCCTCGGCGCGGGATCGCGCATTAACCTCTGTTCATTGCGAATCGCCGAGAACGGAACAACCATTCCGGGCGCTAC
CCTCTGGCGGAGGACTCCAC

Downstream 100 bases:

>100_bases
CCGTCGGCGTTGCCGTTCGCCAGAGCCTTCCATGCGAGGCGCCGTCAGGCCGCCGCTCGCGCCTCGAGAGCCGCAGCCAC
CAGCCTTCGCGAGCCGCGCG

Product: O-linked N-acetylglucosamine transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 742; Mature: 742

Protein sequence:

>742_residues
MQSSVGSRAFQNARLQKRAKKQADVLLPAAVKAYREGRQHEVQALCQQILQDLPQHLGALHLLGVSERDCGHFDQAVLLL
TRAVEIDPRSADVQSDLGLALSRLGRHEEARVRFERAIALKPNFPSAFTHLGNALMSLFRFEEAISAHDRAIALKPDHAE
AYANRGMALMFTSRNGEAAQNFDRALSLQPRLLTALFGKGVASMNLRDFDAALAALNAALAINPKAAAVIAQRGRAYQEL
GRFAEAESDFDAALALEPLLEEALCGKAAVTLVDGNIALSISVINKVLAQNPNSEIAWTLLGVCAAAQGDTATAIDHYDR
ALAIRPNHEDAITKKIFALDFLPDTGVERLQEARRYWWEAIGSRLERRSLGVRNIDPDRRLVVGYVSSDFRDHSAAFAFL
PILRHHDRAKFEVVAYSCSPMKDAKTELCRSLVDRFVDASLWGDDKLADQIQADKVDILVDLSGHSAGHRLTMFARKPAP
IQVSAVGSVTGTGLPVMDYLLADPVVIPAAVRHLFAETIYDLPSLITIEPPPPLPPSPLPMLRNGHVTFGAFNRIDKISE
PTVKLWSQLMQATPGSIIVIKNHSMGDPLLRDRLIARFVAHGIAADRVRCVGKTTRLEHLAMFAEIDISLDPFPQNGGIS
TWESLQMGVPVVTKLGSGPAARAGGAIVKAVGLDEWVGEDDDGYLAIARSFCSRPAELAALRAELPAMVAQSAAGNNALY
TQQVETAYRTFWQDYCRHAPIR

Sequences:

>Translated_742_residues
MQSSVGSRAFQNARLQKRAKKQADVLLPAAVKAYREGRQHEVQALCQQILQDLPQHLGALHLLGVSERDCGHFDQAVLLL
TRAVEIDPRSADVQSDLGLALSRLGRHEEARVRFERAIALKPNFPSAFTHLGNALMSLFRFEEAISAHDRAIALKPDHAE
AYANRGMALMFTSRNGEAAQNFDRALSLQPRLLTALFGKGVASMNLRDFDAALAALNAALAINPKAAAVIAQRGRAYQEL
GRFAEAESDFDAALALEPLLEEALCGKAAVTLVDGNIALSISVINKVLAQNPNSEIAWTLLGVCAAAQGDTATAIDHYDR
ALAIRPNHEDAITKKIFALDFLPDTGVERLQEARRYWWEAIGSRLERRSLGVRNIDPDRRLVVGYVSSDFRDHSAAFAFL
PILRHHDRAKFEVVAYSCSPMKDAKTELCRSLVDRFVDASLWGDDKLADQIQADKVDILVDLSGHSAGHRLTMFARKPAP
IQVSAVGSVTGTGLPVMDYLLADPVVIPAAVRHLFAETIYDLPSLITIEPPPPLPPSPLPMLRNGHVTFGAFNRIDKISE
PTVKLWSQLMQATPGSIIVIKNHSMGDPLLRDRLIARFVAHGIAADRVRCVGKTTRLEHLAMFAEIDISLDPFPQNGGIS
TWESLQMGVPVVTKLGSGPAARAGGAIVKAVGLDEWVGEDDDGYLAIARSFCSRPAELAALRAELPAMVAQSAAGNNALY
TQQVETAYRTFWQDYCRHAPIR
>Mature_742_residues
MQSSVGSRAFQNARLQKRAKKQADVLLPAAVKAYREGRQHEVQALCQQILQDLPQHLGALHLLGVSERDCGHFDQAVLLL
TRAVEIDPRSADVQSDLGLALSRLGRHEEARVRFERAIALKPNFPSAFTHLGNALMSLFRFEEAISAHDRAIALKPDHAE
AYANRGMALMFTSRNGEAAQNFDRALSLQPRLLTALFGKGVASMNLRDFDAALAALNAALAINPKAAAVIAQRGRAYQEL
GRFAEAESDFDAALALEPLLEEALCGKAAVTLVDGNIALSISVINKVLAQNPNSEIAWTLLGVCAAAQGDTATAIDHYDR
ALAIRPNHEDAITKKIFALDFLPDTGVERLQEARRYWWEAIGSRLERRSLGVRNIDPDRRLVVGYVSSDFRDHSAAFAFL
PILRHHDRAKFEVVAYSCSPMKDAKTELCRSLVDRFVDASLWGDDKLADQIQADKVDILVDLSGHSAGHRLTMFARKPAP
IQVSAVGSVTGTGLPVMDYLLADPVVIPAAVRHLFAETIYDLPSLITIEPPPPLPPSPLPMLRNGHVTFGAFNRIDKISE
PTVKLWSQLMQATPGSIIVIKNHSMGDPLLRDRLIARFVAHGIAADRVRCVGKTTRLEHLAMFAEIDISLDPFPQNGGIS
TWESLQMGVPVVTKLGSGPAARAGGAIVKAVGLDEWVGEDDDGYLAIARSFCSRPAELAALRAELPAMVAQSAAGNNALY
TQQVETAYRTFWQDYCRHAPIR

Specific function: May Be Involved In Cell Division. Overexpression Of Nlpi Results In The Loss Of The Rod Morphology And The Formation Of Single Prolate Ellipsoids And Pairs Of Prolate Ellipsoids Joined By Partial Constrictions. [C]

COG id: COG3914

COG function: function code O; Predicted O-linked N-acetylglucosamine transferase, SPINDLY family

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 9 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307148, Length=581, Percent_Identity=25.3012048192771, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI32307150, Length=581, Percent_Identity=25.3012048192771, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI301336134, Length=303, Percent_Identity=25.7425742574257, Blast_Score=95, Evalue=3e-19,
Organism=Homo sapiens, GI83415184, Length=303, Percent_Identity=25.7425742574257, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI170784867, Length=250, Percent_Identity=24, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI118766330, Length=230, Percent_Identity=25.6521739130435, Blast_Score=71, Evalue=4e-12,
Organism=Homo sapiens, GI118766328, Length=230, Percent_Identity=25.6521739130435, Blast_Score=71, Evalue=5e-12,
Organism=Homo sapiens, GI167466177, Length=224, Percent_Identity=23.2142857142857, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI167466175, Length=224, Percent_Identity=23.2142857142857, Blast_Score=68, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115532690, Length=548, Percent_Identity=25.5474452554745, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI115532692, Length=491, Percent_Identity=25.8655804480652, Blast_Score=136, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI25147174, Length=204, Percent_Identity=27.9411764705882, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319387, Length=138, Percent_Identity=28.2608695652174, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI17647755, Length=522, Percent_Identity=25.8620689655172, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24585827, Length=522, Percent_Identity=25.8620689655172, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24585829, Length=522, Percent_Identity=25.8620689655172, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24647123, Length=197, Percent_Identity=25.8883248730964, Blast_Score=69, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008940
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 81018; Mature: 81018

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSSVGSRAFQNARLQKRAKKQADVLLPAAVKAYREGRQHEVQALCQQILQDLPQHLGAL
CCCCHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCE
HLLGVSERDCGHFDQAVLLLTRAVEIDPRSADVQSDLGLALSRLGRHEEARVRFERAIAL
EEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHEEEE
KPNFPSAFTHLGNALMSLFRFEEAISAHDRAIALKPDHAEAYANRGMALMFTSRNGEAAQ
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHCCCEEEEEECCCCCHHH
NFDRALSLQPRLLTALFGKGVASMNLRDFDAALAALNAALAINPKAAAVIAQRGRAYQEL
HHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHEEECCHHHHHHHHHCHHHHHH
GRFAEAESDFDAALALEPLLEEALCGKAAVTLVDGNIALSISVINKVLAQNPNSEIAWTL
HHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCEEEEHHHHHHHHHCCCCCHHHHHH
LGVCAAAQGDTATAIDHYDRALAIRPNHEDAITKKIFALDFLPDTGVERLQEARRYWWEA
HHHHHCCCCCCHHHHHHCCCEEEECCCCHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHH
IGSRLERRSLGVRNIDPDRRLVVGYVSSDFRDHSAAFAFLPILRHHDRAKFEVVAYSCSP
HHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCC
MKDAKTELCRSLVDRFVDASLWGDDKLADQIQADKVDILVDLSGHSAGHRLTMFARKPAP
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCEEEEEECCCCC
IQVSAVGSVTGTGLPVMDYLLADPVVIPAAVRHLFAETIYDLPSLITIEPPPPLPPSPLP
EEEEECCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
MLRNGHVTFGAFNRIDKISEPTVKLWSQLMQATPGSIIVIKNHSMGDPLLRDRLIARFVA
CCCCCCEEEHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHH
HGIAADRVRCVGKTTRLEHLAMFAEIDISLDPFPQNGGISTWESLQMGVPVVTKLGSGPA
HCHHHHHHHHHCCHHHHHHHHHHHHEECEECCCCCCCCCCCHHHHHCCCHHHHCCCCCCC
ARAGGAIVKAVGLDEWVGEDDDGYLAIARSFCSRPAELAALRAELPAMVAQSAAGNNALY
CCCCCCEEEEECCHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEE
TQQVETAYRTFWQDYCRHAPIR
HHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQSSVGSRAFQNARLQKRAKKQADVLLPAAVKAYREGRQHEVQALCQQILQDLPQHLGAL
CCCCHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCE
HLLGVSERDCGHFDQAVLLLTRAVEIDPRSADVQSDLGLALSRLGRHEEARVRFERAIAL
EEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHEEEE
KPNFPSAFTHLGNALMSLFRFEEAISAHDRAIALKPDHAEAYANRGMALMFTSRNGEAAQ
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHCCCEEEEEECCCCCHHH
NFDRALSLQPRLLTALFGKGVASMNLRDFDAALAALNAALAINPKAAAVIAQRGRAYQEL
HHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHEEECCHHHHHHHHHCHHHHHH
GRFAEAESDFDAALALEPLLEEALCGKAAVTLVDGNIALSISVINKVLAQNPNSEIAWTL
HHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCEEEEHHHHHHHHHCCCCCHHHHHH
LGVCAAAQGDTATAIDHYDRALAIRPNHEDAITKKIFALDFLPDTGVERLQEARRYWWEA
HHHHHCCCCCCHHHHHHCCCEEEECCCCHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHH
IGSRLERRSLGVRNIDPDRRLVVGYVSSDFRDHSAAFAFLPILRHHDRAKFEVVAYSCSP
HHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCC
MKDAKTELCRSLVDRFVDASLWGDDKLADQIQADKVDILVDLSGHSAGHRLTMFARKPAP
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCEEEEEECCCCC
IQVSAVGSVTGTGLPVMDYLLADPVVIPAAVRHLFAETIYDLPSLITIEPPPPLPPSPLP
EEEEECCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
MLRNGHVTFGAFNRIDKISEPTVKLWSQLMQATPGSIIVIKNHSMGDPLLRDRLIARFVA
CCCCCCEEEHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHH
HGIAADRVRCVGKTTRLEHLAMFAEIDISLDPFPQNGGISTWESLQMGVPVVTKLGSGPA
HCHHHHHHHHHCCHHHHHHHHHHHHEECEECCCCCCCCCCCHHHHHCCCHHHHCCCCCCC
ARAGGAIVKAVGLDEWVGEDDDGYLAIARSFCSRPAELAALRAELPAMVAQSAAGNNALY
CCCCCCEEEEECCHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEE
TQQVETAYRTFWQDYCRHAPIR
HHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087; 9697413 [H]