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The map label for this gene is oxa5 [H]

Identifier: 146341530

GI number: 146341530

Start: 4817963

End: 4818781

Strand: Reverse

Name: oxa5 [H]

Synonym: BRADO4627

Alternate gene names: 146341530

Gene position: 4818781-4817963 (Counterclockwise)

Preceding gene: 146341531

Following gene: 146341526

Centisome position: 64.62

GC content: 65.57

Gene sequence:

>819_bases
ATGCCGATAATGAGCCGCCGTCACGTGCTTGGCCTGATCGCCGGGGCAGGCCTGTTGCCCGCGCGCACGCTGGCGCATGT
CGCGCCGCCGCGAAACGAGATCCGCCCCTCGCTCGCGCAGCGCTTCACCGATGTGGGGACCAAGGGCACGTTCCTCGCCT
ACAAGGTCGAGGAATATCTCATCATCGCCAGCGACACTGAGCGCTCGGGCGAGGCGAGGCTGCCGGCCTCGACCTTCAAG
ATCGCCAACTCGTTGATCGCGCTGGACACCGGCGTCGTCGAGGATCCCGACAAGGATGTGTTCAAGTGGGACGGCGTCAT
CAGACCGATCGAGGCCTGGAACAAGGATCACACCCTGCGCAGCGCGATCGCCGTCTCTGCCGTGCCGGTCTATCAGGAGA
TCGCGCGCCGGATCGGGCCCGAGCGGATGCAGAAATATCTCGAGGAGCTCGACTACGGCAATCACGACATTGGCGGCGGC
ATCGATCAGTTCTGGCTGACTGGGAGCTTGCGCATCGATCCGGTCGAGCAGGTCGATTTCATCGACCGCCTCCGGCGCGG
CGCGCTGCCGGTCTCCAAGCGCAGCCAGGACCTGACGCGCGACATCATCCCGGTGACCAAGGGCGGCGACGCCGTCATTC
ACGCGAAGTCGGGCTTGCTGGGAAAAGAGCAGGGCTCGCTCGGCTGGATGGTGGGCTGGGTCGACAAGGGCGACCAGCCG
ACCGTGTTCGCGATGAACATGGACTGCCCCGAGCCGCGCCACGTCGAGGCCCGGATGACGCTGACGCAGGCGTGCCTCAA
GGACATCGGCGCAATTTAG

Upstream 100 bases:

>100_bases
GGCCGGTGCGCTAGCGCGCGCCGCATTGTGATCTCCGTCATGCCTCGATCCCCATCGCCCTGTGATAGGGAGAAACGGAC
TTCGACGGAGAGATGACGCA

Downstream 100 bases:

>100_bases
CTGTTGTAGCCCGGATGAGCGCAGCGACATCCGGGTTCACCGCGACAGCGCATGAGATCCCGGATGTCGCTGCGCTCATC
CGGGCTACGAAGCTGCCGTA

Product: beta-lactamase (OXA-5), class D

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MPIMSRRHVLGLIAGAGLLPARTLAHVAPPRNEIRPSLAQRFTDVGTKGTFLAYKVEEYLIIASDTERSGEARLPASTFK
IANSLIALDTGVVEDPDKDVFKWDGVIRPIEAWNKDHTLRSAIAVSAVPVYQEIARRIGPERMQKYLEELDYGNHDIGGG
IDQFWLTGSLRIDPVEQVDFIDRLRRGALPVSKRSQDLTRDIIPVTKGGDAVIHAKSGLLGKEQGSLGWMVGWVDKGDQP
TVFAMNMDCPEPRHVEARMTLTQACLKDIGAI

Sequences:

>Translated_272_residues
MPIMSRRHVLGLIAGAGLLPARTLAHVAPPRNEIRPSLAQRFTDVGTKGTFLAYKVEEYLIIASDTERSGEARLPASTFK
IANSLIALDTGVVEDPDKDVFKWDGVIRPIEAWNKDHTLRSAIAVSAVPVYQEIARRIGPERMQKYLEELDYGNHDIGGG
IDQFWLTGSLRIDPVEQVDFIDRLRRGALPVSKRSQDLTRDIIPVTKGGDAVIHAKSGLLGKEQGSLGWMVGWVDKGDQP
TVFAMNMDCPEPRHVEARMTLTQACLKDIGAI
>Mature_271_residues
PIMSRRHVLGLIAGAGLLPARTLAHVAPPRNEIRPSLAQRFTDVGTKGTFLAYKVEEYLIIASDTERSGEARLPASTFKI
ANSLIALDTGVVEDPDKDVFKWDGVIRPIEAWNKDHTLRSAIAVSAVPVYQEIARRIGPERMQKYLEELDYGNHDIGGGI
DQFWLTGSLRIDPVEQVDFIDRLRRGALPVSKRSQDLTRDIIPVTKGGDAVIHAKSGLLGKEQGSLGWMVGWVDKGDQPT
VFAMNMDCPEPRHVEARMTLTQACLKDIGAI

Specific function: Hydrolyzes both oxacillin and methicillin [H]

COG id: COG2602

COG function: function code V; Beta-lactamase class D

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-D beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR002137
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00905 Transpeptidase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 30018; Mature: 29887

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00337 BETA_LACTAMASE_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIMSRRHVLGLIAGAGLLPARTLAHVAPPRNEIRPSLAQRFTDVGTKGTFLAYKVEEYL
CCCCCHHHHHHHHHCCCCCHHHHHHHCCCCHHHCCHHHHHHHHHCCCCCEEEEEEEEEEE
IIASDTERSGEARLPASTFKIANSLIALDTGVVEDPDKDVFKWDGVIRPIEAWNKDHTLR
EEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCEECCHHHCCCCHHHH
SAIAVSAVPVYQEIARRIGPERMQKYLEELDYGNHDIGGGIDQFWLTGSLRIDPVEQVDF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCHHHEEECCEEECCHHHHHH
IDRLRRGALPVSKRSQDLTRDIIPVTKGGDAVIHAKSGLLGKEQGSLGWMVGWVDKGDQP
HHHHHHCCCCCCCCHHHHHHHCCCEECCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCC
TVFAMNMDCPEPRHVEARMTLTQACLKDIGAI
EEEEEECCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PIMSRRHVLGLIAGAGLLPARTLAHVAPPRNEIRPSLAQRFTDVGTKGTFLAYKVEEYL
CCCCHHHHHHHHHCCCCCHHHHHHHCCCCHHHCCHHHHHHHHHCCCCCEEEEEEEEEEE
IIASDTERSGEARLPASTFKIANSLIALDTGVVEDPDKDVFKWDGVIRPIEAWNKDHTLR
EEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCEECCHHHCCCCHHHH
SAIAVSAVPVYQEIARRIGPERMQKYLEELDYGNHDIGGGIDQFWLTGSLRIDPVEQVDF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCHHHEEECCEEECCHHHHHH
IDRLRRGALPVSKRSQDLTRDIIPVTKGGDAVIHAKSGLLGKEQGSLGWMVGWVDKGDQP
HHHHHHCCCCCCCCHHHHHHHCCCEECCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCC
TVFAMNMDCPEPRHVEARMTLTQACLKDIGAI
EEEEEECCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1495394 [H]