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The map label for this gene is coxL [H]

Identifier: 146341491

GI number: 146341491

Start: 4779297

End: 4781672

Strand: Reverse

Name: coxL [H]

Synonym: BRADO4584

Alternate gene names: 146341491

Gene position: 4781672-4779297 (Counterclockwise)

Preceding gene: 146341492

Following gene: 146341490

Centisome position: 64.13

GC content: 66.37

Gene sequence:

>2376_bases
ATGACCGCGCCGCTGACATCGCTGGATCGTCCCAATTCCTATATCGGCCGCTCTGTCCCACGCCCGAATGCCAAGCGGCT
GCTGGCGGGGCGCGGGCGCTACGTCACCGATCTCCGCCTGCCGCGCATGCTTCATGCGGCCTTTTTGCGCAGCCCACATG
CGCATGCGCGCATTCTCAGCATCGACATCGAAGCTGCGCGCGCGCTGGCCGGAGTGCATCTGGTCGCGACCGGCGCAGAC
CTGGCCAGGATCTGCACGCCCTGGACAGGAACGCTCGATCATTTCAAGGGGATGGTCTCGGAGCCGCAGCTGCCATTGCC
GCTCGATCGCGTTGTATGGGCCGGCCAAGCCGTGGTCGCTGTGGTCGCCGAGAGCAGGGCGGTCGCGGAGGACGCGCTGG
AGCTGATCGCGGTCGACTACGAGGAGCTGCCGGCGGTGGTCGATCTCGACGCCGCGCGCGCACCCGACGCTCCCACGGTC
AACCCGGCCGCATCGTCCAACATCTGCTTCCGCGCCCAGCTCGATAGCGGCGGTGTCGACGAGGCCTTTGCGTCCGCGGC
TCACGTCGTCGAGCAGGAGTTCAGCTTTGGCCGGCACACGCCTGTCACGCTGGAGCCACGCGCCGTCGTCGCCGACTACG
AGTCCGACACCGGCATGCTGACGGTGCACCACGCGACGCAGACGCCGTATCAGTTCCAGGATCTGTATTCACGCCACTAC
GGCATCCCTGAAGCGCGCGTGCGCGTGATCGCGCCCGACATCGGCGGCTCGTTCGGGATGAAGCTGCACGTCTATCACGA
GGACATGGCGGTGGTCGGGCTGTCGATCCTGCTCGGGCGTCCGGTGAAGTATGTCGCCGACCGGATCGAGTCGTTCGTCT
CCGACATCCATGCCCGCGATCACCACGTGCGGGCGCGCATGGCGGTCGACGCCGACGGCAAGATCCTCGCCATGGACATC
CATGACGCCACCGCGGTCGGCGCCTTCTCGACCTATCCGCGCACCAGCGTGGTCGAGGGCAACCAGGTGATCCGCCTGAT
CGGCGCGCCCTATGATTTCAAGTCGTATCGGGCGGTGCTGGAGGTCGTGTTTCAGAACAAGGTGCAGACCAGTCAATATC
GCGCCGTCGGCCATCCCATCGCCTGCGCCGTCACCGAGCGCATGGTGGATCTTGCCGCGGAACGCATCGGCGCCGATCCC
CTCGCGATGCGCGCCAGGAACGTGATCGCCGACGATGCCTATCCAACGGCGTCCCCGACCGGCTACAAGTTCGAAGCGCT
CTCGCACGAGGCTTGCCTGCGGCGCTTGCGCGAGATCATGAGCTACGACGGATTGCGCGCCGAGCAGGCGGAGCTGCGCC
GGCGCGGTGTCCACCGCGGCATCGGTATCGCGACCTTCGTCGAAATCACCAATCCGAGTCCGGCCTTCTATGGCGTCGGC
GGCGCCCGTATCTCCTCGCAGGACGGCGCGACGCTCAGCCTCACGCCGTCCGGCGAGGTGCGCTGCGCCATCTCGGTCAC
CGAGCAGGGGCAGGGCACCGAGGCGATCATCGGCCAGATCGTCGCCGATCAGCTCGGTCTCGCCCAGGAGCACGTGAAGA
TCATCACCGGCGATACCGAAGTCACGCCGCATGGCGGTGCGACCTGGGCCTGTCGCGGCGCCGGCATCGGCGGCGAGACC
GCGCTGCAGGCCGCGCGGCAGCTCAAGGCCAATATCGTGGAGATCGCCGCTCTGATCCTGCAGGAGCGGCCGGCCGCACT
CGACATCGTCGATGGGCAAGTCGTGGGCAAGGCGACCCGGCAGCCGCGCATCCCGGTCGCCGAAATCGCGCGCATCGCCT
ATTTCCGCTCGGACACGCTGCCGCCGGGTACGCAGGCGCAGCTGACCGTCAGCCATCACTTCGCGCCGCAGGGCTATCCC
TTCGCGTTCACGAATGGCGTGCAGGGCTGCTATCTCGAGGTCGACACAGACACCGGCTTGATCAAGCTGTTGAAGCACTA
CGTCGTCGAGGATTGCGGCCGCATCATCAATCCGATGCTGGTCGACGAGCAGCTGCGGGGCGGCGTCGTGCAGGGATTGG
GTGCGGCGCTGTTCGAGGAATGCCGTTATAGTGAGACCGGCCAATTGCTGAACGGCTCGTTGGCTGATTATCTCGTGCCG
ATGGCGATGGAGATGCCGGATATCGTCATCGACCACGTCGAGACGCCGACGGCGGACACCATTCTGGGCGCGAAAGGATG
CGGCGAGGCCGGCACGGCGGCGGCATCGGCCTGCGTGCTCAATGCGGTGAATGACGCGCTGACGCCGTTCGGCGCATCCA
TCAATGCCATTCCGATCACGCCTGCGCGCGTGCTCAAGTCGCTCAATCAATACTAA

Upstream 100 bases:

>100_bases
CCGGCAATTTCTGCCGCTGCACCGGATACGAGGCGATCGTCGATTCCATTGCCGCCGTTGCCGAGGCGCGTGCGGCAAAG
GCCGCCGAGGGGCCGTCGCG

Downstream 100 bases:

>100_bases
ACAAAACAAGATGAGGGAGGACATCATGCCAGGCTTCGAGACCAAGCTGCGACCTGCCGGACTATCCCGCCGCAAGGCAT
TGATGGCCATGTCGGCGGGC

Product: putative carbon-monoxide dehydrogenase large subunit, coxL-like protein

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 791; Mature: 790

Protein sequence:

>791_residues
MTAPLTSLDRPNSYIGRSVPRPNAKRLLAGRGRYVTDLRLPRMLHAAFLRSPHAHARILSIDIEAARALAGVHLVATGAD
LARICTPWTGTLDHFKGMVSEPQLPLPLDRVVWAGQAVVAVVAESRAVAEDALELIAVDYEELPAVVDLDAARAPDAPTV
NPAASSNICFRAQLDSGGVDEAFASAAHVVEQEFSFGRHTPVTLEPRAVVADYESDTGMLTVHHATQTPYQFQDLYSRHY
GIPEARVRVIAPDIGGSFGMKLHVYHEDMAVVGLSILLGRPVKYVADRIESFVSDIHARDHHVRARMAVDADGKILAMDI
HDATAVGAFSTYPRTSVVEGNQVIRLIGAPYDFKSYRAVLEVVFQNKVQTSQYRAVGHPIACAVTERMVDLAAERIGADP
LAMRARNVIADDAYPTASPTGYKFEALSHEACLRRLREIMSYDGLRAEQAELRRRGVHRGIGIATFVEITNPSPAFYGVG
GARISSQDGATLSLTPSGEVRCAISVTEQGQGTEAIIGQIVADQLGLAQEHVKIITGDTEVTPHGGATWACRGAGIGGET
ALQAARQLKANIVEIAALILQERPAALDIVDGQVVGKATRQPRIPVAEIARIAYFRSDTLPPGTQAQLTVSHHFAPQGYP
FAFTNGVQGCYLEVDTDTGLIKLLKHYVVEDCGRIINPMLVDEQLRGGVVQGLGAALFEECRYSETGQLLNGSLADYLVP
MAMEMPDIVIDHVETPTADTILGAKGCGEAGTAAASACVLNAVNDALTPFGASINAIPITPARVLKSLNQY

Sequences:

>Translated_791_residues
MTAPLTSLDRPNSYIGRSVPRPNAKRLLAGRGRYVTDLRLPRMLHAAFLRSPHAHARILSIDIEAARALAGVHLVATGAD
LARICTPWTGTLDHFKGMVSEPQLPLPLDRVVWAGQAVVAVVAESRAVAEDALELIAVDYEELPAVVDLDAARAPDAPTV
NPAASSNICFRAQLDSGGVDEAFASAAHVVEQEFSFGRHTPVTLEPRAVVADYESDTGMLTVHHATQTPYQFQDLYSRHY
GIPEARVRVIAPDIGGSFGMKLHVYHEDMAVVGLSILLGRPVKYVADRIESFVSDIHARDHHVRARMAVDADGKILAMDI
HDATAVGAFSTYPRTSVVEGNQVIRLIGAPYDFKSYRAVLEVVFQNKVQTSQYRAVGHPIACAVTERMVDLAAERIGADP
LAMRARNVIADDAYPTASPTGYKFEALSHEACLRRLREIMSYDGLRAEQAELRRRGVHRGIGIATFVEITNPSPAFYGVG
GARISSQDGATLSLTPSGEVRCAISVTEQGQGTEAIIGQIVADQLGLAQEHVKIITGDTEVTPHGGATWACRGAGIGGET
ALQAARQLKANIVEIAALILQERPAALDIVDGQVVGKATRQPRIPVAEIARIAYFRSDTLPPGTQAQLTVSHHFAPQGYP
FAFTNGVQGCYLEVDTDTGLIKLLKHYVVEDCGRIINPMLVDEQLRGGVVQGLGAALFEECRYSETGQLLNGSLADYLVP
MAMEMPDIVIDHVETPTADTILGAKGCGEAGTAAASACVLNAVNDALTPFGASINAIPITPARVLKSLNQY
>Mature_790_residues
TAPLTSLDRPNSYIGRSVPRPNAKRLLAGRGRYVTDLRLPRMLHAAFLRSPHAHARILSIDIEAARALAGVHLVATGADL
ARICTPWTGTLDHFKGMVSEPQLPLPLDRVVWAGQAVVAVVAESRAVAEDALELIAVDYEELPAVVDLDAARAPDAPTVN
PAASSNICFRAQLDSGGVDEAFASAAHVVEQEFSFGRHTPVTLEPRAVVADYESDTGMLTVHHATQTPYQFQDLYSRHYG
IPEARVRVIAPDIGGSFGMKLHVYHEDMAVVGLSILLGRPVKYVADRIESFVSDIHARDHHVRARMAVDADGKILAMDIH
DATAVGAFSTYPRTSVVEGNQVIRLIGAPYDFKSYRAVLEVVFQNKVQTSQYRAVGHPIACAVTERMVDLAAERIGADPL
AMRARNVIADDAYPTASPTGYKFEALSHEACLRRLREIMSYDGLRAEQAELRRRGVHRGIGIATFVEITNPSPAFYGVGG
ARISSQDGATLSLTPSGEVRCAISVTEQGQGTEAIIGQIVADQLGLAQEHVKIITGDTEVTPHGGATWACRGAGIGGETA
LQAARQLKANIVEIAALILQERPAALDIVDGQVVGKATRQPRIPVAEIARIAYFRSDTLPPGTQAQLTVSHHFAPQGYPF
AFTNGVQGCYLEVDTDTGLIKLLKHYVVEDCGRIINPMLVDEQLRGGVVQGLGAALFEECRYSETGQLLNGSLADYLVPM
AMEMPDIVIDHVETPTADTILGAKGCGEAGTAAASACVLNAVNDALTPFGASINAIPITPARVLKSLNQY

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=768, Percent_Identity=24.21875, Blast_Score=158, Evalue=2e-38,
Organism=Homo sapiens, GI91823271, Length=774, Percent_Identity=22.609819121447, Blast_Score=135, Evalue=1e-31,
Organism=Escherichia coli, GI1789230, Length=785, Percent_Identity=29.2993630573248, Blast_Score=271, Evalue=1e-73,
Organism=Escherichia coli, GI1789246, Length=833, Percent_Identity=25.2100840336134, Blast_Score=192, Evalue=8e-50,
Organism=Escherichia coli, GI1786478, Length=791, Percent_Identity=23.6409608091024, Blast_Score=119, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17540638, Length=733, Percent_Identity=23.0559345156889, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI17737937, Length=736, Percent_Identity=26.3586956521739, Blast_Score=148, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24647199, Length=778, Percent_Identity=22.7506426735219, Blast_Score=111, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 84871; Mature: 84739

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPLTSLDRPNSYIGRSVPRPNAKRLLAGRGRYVTDLRLPRMLHAAFLRSPHAHARILS
CCCCCCCCCCCCHHHCCCCCCCCHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCEEEEE
IDIEAARALAGVHLVATGADLARICTPWTGTLDHFKGMVSEPQLPLPLDRVVWAGQAVVA
EEHHHHHHHHCEEEEECCCHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHHCCCHHEE
VVAESRAVAEDALELIAVDYEELPAVVDLDAARAPDAPTVNPAASSNICFRAQLDSGGVD
HHHHHHHHHHHHHHHHHCCHHHCCCEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCH
EAFASAAHVVEQEFSFGRHTPVTLEPRAVVADYESDTGMLTVHHATQTPYQFQDLYSRHY
HHHHHHHHHHHHHHCCCCCCCEEECCCEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHC
GIPEARVRVIAPDIGGSFGMKLHVYHEDMAVVGLSILLGRPVKYVADRIESFVSDIHARD
CCCCCEEEEEECCCCCCCCCEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
HHVRARMAVDADGKILAMDIHDATAVGAFSTYPRTSVVEGNQVIRLIGAPYDFKSYRAVL
HHEEEEEEECCCCCEEEEECCCCHHCCCCCCCCCCEEECCCCEEEEECCCCCHHHHHHHH
EVVFQNKVQTSQYRAVGHPIACAVTERMVDLAAERIGADPLAMRARNVIADDAYPTASPT
HHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCC
GYKFEALSHEACLRRLREIMSYDGLRAEQAELRRRGVHRGIGIATFVEITNPSPAFYGVG
CEEEHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEECC
GARISSQDGATLSLTPSGEVRCAISVTEQGQGTEAIIGQIVADQLGLAQEHVKIITGDTE
CCEECCCCCCEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCE
VTPHGGATWACRGAGIGGETALQAARQLKANIVEIAALILQERPAALDIVDGQVVGKATR
ECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEECCCCC
QPRIPVAEIARIAYFRSDTLPPGTQAQLTVSHHFAPQGYPFAFTNGVQGCYLEVDTDTGL
CCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCEEEECCCCEEEEEEECCCHH
IKLLKHYVVEDCGRIINPMLVDEQLRGGVVQGLGAALFEECRYSETGQLLNGSLADYLVP
HHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHH
MAMEMPDIVIDHVETPTADTILGAKGCGEAGTAAASACVLNAVNDALTPFGASINAIPIT
HHHCCCHHHHHCCCCCCCHHEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCC
PARVLKSLNQY
HHHHHHHHHCC
>Mature Secondary Structure 
TAPLTSLDRPNSYIGRSVPRPNAKRLLAGRGRYVTDLRLPRMLHAAFLRSPHAHARILS
CCCCCCCCCCCHHHCCCCCCCCHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCEEEEE
IDIEAARALAGVHLVATGADLARICTPWTGTLDHFKGMVSEPQLPLPLDRVVWAGQAVVA
EEHHHHHHHHCEEEEECCCHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHHCCCHHEE
VVAESRAVAEDALELIAVDYEELPAVVDLDAARAPDAPTVNPAASSNICFRAQLDSGGVD
HHHHHHHHHHHHHHHHHCCHHHCCCEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCH
EAFASAAHVVEQEFSFGRHTPVTLEPRAVVADYESDTGMLTVHHATQTPYQFQDLYSRHY
HHHHHHHHHHHHHHCCCCCCCEEECCCEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHC
GIPEARVRVIAPDIGGSFGMKLHVYHEDMAVVGLSILLGRPVKYVADRIESFVSDIHARD
CCCCCEEEEEECCCCCCCCCEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
HHVRARMAVDADGKILAMDIHDATAVGAFSTYPRTSVVEGNQVIRLIGAPYDFKSYRAVL
HHEEEEEEECCCCCEEEEECCCCHHCCCCCCCCCCEEECCCCEEEEECCCCCHHHHHHHH
EVVFQNKVQTSQYRAVGHPIACAVTERMVDLAAERIGADPLAMRARNVIADDAYPTASPT
HHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCC
GYKFEALSHEACLRRLREIMSYDGLRAEQAELRRRGVHRGIGIATFVEITNPSPAFYGVG
CEEEHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEECC
GARISSQDGATLSLTPSGEVRCAISVTEQGQGTEAIIGQIVADQLGLAQEHVKIITGDTE
CCEECCCCCCEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCE
VTPHGGATWACRGAGIGGETALQAARQLKANIVEIAALILQERPAALDIVDGQVVGKATR
ECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEECCCCC
QPRIPVAEIARIAYFRSDTLPPGTQAQLTVSHHFAPQGYPFAFTNGVQGCYLEVDTDTGL
CCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCEEEECCCCEEEEEEECCCHH
IKLLKHYVVEDCGRIINPMLVDEQLRGGVVQGLGAALFEECRYSETGQLLNGSLADYLVP
HHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHH
MAMEMPDIVIDHVETPTADTILGAKGCGEAGTAAASACVLNAVNDALTPFGASINAIPIT
HHHCCCHHHHHCCCCCCCHHEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCC
PARVLKSLNQY
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 12515558; 10430865; 12475995 [H]