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The map label for this gene is yafC [H]

Identifier: 146341482

GI number: 146341482

Start: 4770897

End: 4771802

Strand: Direct

Name: yafC [H]

Synonym: BRADO4575

Alternate gene names: 146341482

Gene position: 4770897-4771802 (Clockwise)

Preceding gene: 146341480

Following gene: 146341484

Centisome position: 63.98

GC content: 70.42

Gene sequence:

>906_bases
ATGCACGAGATCTCCGACTGGAGCCTGTTGCGCTCCTTCCTGGCCGTGGTCCGGCGCGGCAGCCTGTCCGCCGCGGCGCG
CGCGACCGGGCTGACGCAGCCGACGGTCGGCCGTCACATCGACGAGCTGGAAGCCGGCCTCGGCGTCGCCCTGTTCACCC
GCTCGCAGGCCGGCCTGCTGCCGACCGAGTCGGCCACGGCGCTGCTGCCGCATGCCGAGGCGATGGAAGCGGCGTTCGCC
GCGCTGGTCCGGACCGCAAAAACCGGCGGCGATGCGCAACAGCCGCGCGGCGTGGTCAGGATCTCGGCGAGCGAGATCGT
CGGCACCTTCGTGCTGCCGCCGATCCTCGCCGGCATCCGCCACCGCTTTCCCGAGATCGTCATCGAGCTCGTGCTCAACA
ACCGCACCGACGACCTGCTGCGGCGCGACGCCGACATCGCGGTGCGGATGATCCGGCCCAAGCAGGACGGCCTCGTCGCC
CGCCGCATCGGCAGCGTTCCGCTCGGCCTGTATGCCCATCGCGACTACGTCGCCCGCTTCGGCCTGCCCGACACGATCGA
ACAGCTCGGCGCGCACCACATCATCGGCTTCGACCGCGACGATCATTCCGCGCGCTCGGTCGCGAGCTCACAGCTGCCGA
TCTCGCGCGAGCTCTTCTCCTATCGCACCGACTCCGACGTCGCCCAGGTGACCGCGATCGAAGCCGGCCTAGGCATCGGC
GGCATGCAGAAAGCCATGGCGAGGCGCAATCCCGCGCTGCTCCCGGTGCTCGCCGGCCAGATCGCCTTTGAGCTCGATTG
CTGGCTCGCCGTGCACGAGGACCAGAAGGACTCCCCGCCGATCCGCGTGATGGTCGATGGACTGGCCGAGGGGCTGGCGC
GATGGGTCAGCGAGGGCAGCCGGTGA

Upstream 100 bases:

>100_bases
GTGTCGGACATGGCTGATCTCCTTGCTGTGTCCAGCAAGCTGGACCGGCCGTCGCAAAACGAAAATTGCCAAACATTCTT
TAGCCGCTATACATTTTCTT

Downstream 100 bases:

>100_bases
CGGCGGAGACGCGCCGCGTGGCGCGCCTTGTTTCGTCCGCGCGCAACGATGCAAGCGCCGGCTGATCTCCCATGCCGCTC
GGCCTATTTGCCGTCGTCGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MHEISDWSLLRSFLAVVRRGSLSAAARATGLTQPTVGRHIDELEAGLGVALFTRSQAGLLPTESATALLPHAEAMEAAFA
ALVRTAKTGGDAQQPRGVVRISASEIVGTFVLPPILAGIRHRFPEIVIELVLNNRTDDLLRRDADIAVRMIRPKQDGLVA
RRIGSVPLGLYAHRDYVARFGLPDTIEQLGAHHIIGFDRDDHSARSVASSQLPISRELFSYRTDSDVAQVTAIEAGLGIG
GMQKAMARRNPALLPVLAGQIAFELDCWLAVHEDQKDSPPIRVMVDGLAEGLARWVSEGSR

Sequences:

>Translated_301_residues
MHEISDWSLLRSFLAVVRRGSLSAAARATGLTQPTVGRHIDELEAGLGVALFTRSQAGLLPTESATALLPHAEAMEAAFA
ALVRTAKTGGDAQQPRGVVRISASEIVGTFVLPPILAGIRHRFPEIVIELVLNNRTDDLLRRDADIAVRMIRPKQDGLVA
RRIGSVPLGLYAHRDYVARFGLPDTIEQLGAHHIIGFDRDDHSARSVASSQLPISRELFSYRTDSDVAQVTAIEAGLGIG
GMQKAMARRNPALLPVLAGQIAFELDCWLAVHEDQKDSPPIRVMVDGLAEGLARWVSEGSR
>Mature_301_residues
MHEISDWSLLRSFLAVVRRGSLSAAARATGLTQPTVGRHIDELEAGLGVALFTRSQAGLLPTESATALLPHAEAMEAAFA
ALVRTAKTGGDAQQPRGVVRISASEIVGTFVLPPILAGIRHRFPEIVIELVLNNRTDDLLRRDADIAVRMIRPKQDGLVA
RRIGSVPLGLYAHRDYVARFGLPDTIEQLGAHHIIGFDRDDHSARSVASSQLPISRELFSYRTDSDVAQVTAIEAGLGIG
GMQKAMARRNPALLPVLAGQIAFELDCWLAVHEDQKDSPPIRVMVDGLAEGLARWVSEGSR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=287, Percent_Identity=27.5261324041812, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1787589, Length=201, Percent_Identity=27.8606965174129, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789440, Length=201, Percent_Identity=26.3681592039801, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787128, Length=197, Percent_Identity=26.9035532994924, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789639, Length=238, Percent_Identity=24.7899159663866, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788481, Length=128, Percent_Identity=32.03125, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87082132, Length=169, Percent_Identity=31.3609467455621, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32551; Mature: 32551

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEISDWSLLRSFLAVVRRGSLSAAARATGLTQPTVGRHIDELEAGLGVALFTRSQAGLL
CCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCC
PTESATALLPHAEAMEAAFAALVRTAKTGGDAQQPRGVVRISASEIVGTFVLPPILAGIR
CCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
HRFPEIVIELVLNNRTDDLLRRDADIAVRMIRPKQDGLVARRIGSVPLGLYAHRDYVARF
HHHHHHHHHHHHCCCHHHHHHCCHHHEEEEECCCCCCHHHHHHCCCCCCHHHHHHHHHHC
GLPDTIEQLGAHHIIGFDRDDHSARSVASSQLPISRELFSYRTDSDVAQVTAIEAGLGIG
CCCHHHHHCCCCEEEECCCCCHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHCCCCC
GMQKAMARRNPALLPVLAGQIAFELDCWLAVHEDQKDSPPIRVMVDGLAEGLARWVSEGS
HHHHHHHHCCCCEEHHHHHHHHEEEEEEEEEECCCCCCCCCEEHHHHHHHHHHHHHHCCC
R
C
>Mature Secondary Structure
MHEISDWSLLRSFLAVVRRGSLSAAARATGLTQPTVGRHIDELEAGLGVALFTRSQAGLL
CCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCC
PTESATALLPHAEAMEAAFAALVRTAKTGGDAQQPRGVVRISASEIVGTFVLPPILAGIR
CCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
HRFPEIVIELVLNNRTDDLLRRDADIAVRMIRPKQDGLVARRIGSVPLGLYAHRDYVARF
HHHHHHHHHHHHCCCHHHHHHCCHHHEEEEECCCCCCHHHHHHCCCCCCHHHHHHHHHHC
GLPDTIEQLGAHHIIGFDRDDHSARSVASSQLPISRELFSYRTDSDVAQVTAIEAGLGIG
CCCHHHHHCCCCEEEECCCCCHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHCCCCC
GMQKAMARRNPALLPVLAGQIAFELDCWLAVHEDQKDSPPIRVMVDGLAEGLARWVSEGS
HHHHHHHHCCCCEEHHHHHHHHEEEEEEEEEECCCCCCCCCEEHHHHHHHHHHHHHHCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]