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The map label for this gene is arsC [H]

Identifier: 146341360

GI number: 146341360

Start: 4645646

End: 4646056

Strand: Reverse

Name: arsC [H]

Synonym: BRADO4444

Alternate gene names: 146341360

Gene position: 4646056-4645646 (Counterclockwise)

Preceding gene: 146341363

Following gene: 146341359

Centisome position: 62.31

GC content: 62.29

Gene sequence:

>411_bases
TTGACAAGTGTAACGATCTTTCACAATCCTGCCTGCGGCACGTCGCGCAACACGCTGGCGATGATCCGCGCCTCGGGCGA
GGAGCCGGATGTGATCGAATATCTAAAGACGCCGCCGAGCCGCGAGCAGCTGATTGCCCTGATCAATGCGATGGGCGTGA
GGGTGCGAGACGTGCTGCGTGAAAAGGGGACGCCCTATGCCGACCTCGGGCTCGCCGACCCCAAATGGACCGATGACCAG
CTGATCGAGGCGATGCTCGTCTATCCGATCCTCATCAACCGGCCGATCGTGGTGACGGGCAAGGGCGCGCGGCTGTGCCG
TCCGTCAGAGCTTGTGCTCGACCTGCTCGATCGTCCGGTCTCCTCCTTCACCAAGGAGGATGGCGAGGTGGTGAGCTGGA
CTGCGAAGTGA

Upstream 100 bases:

>100_bases
GGCGCCCTGTCAATCATGGTGCACGGGAGTTGCATTGCGCTGTGCTAACATGGATGGCGCGCCTCATAGGACGCGCTTCT
TTTGAAGTCGGGGACTGATT

Downstream 100 bases:

>100_bases
TGTTTGTCAAAACCAGCGTTGACGAGTTGGATGCATGGACCTATCAGCCCGCCGCGATCTGATCAGCTGGCTTGTTTCCC
AAAGCCTGACCGGCGTGCCG

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MTSVTIFHNPACGTSRNTLAMIRASGEEPDVIEYLKTPPSREQLIALINAMGVRVRDVLREKGTPYADLGLADPKWTDDQ
LIEAMLVYPILINRPIVVTGKGARLCRPSELVLDLLDRPVSSFTKEDGEVVSWTAK

Sequences:

>Translated_136_residues
MTSVTIFHNPACGTSRNTLAMIRASGEEPDVIEYLKTPPSREQLIALINAMGVRVRDVLREKGTPYADLGLADPKWTDDQ
LIEAMLVYPILINRPIVVTGKGARLCRPSELVLDLLDRPVSSFTKEDGEVVSWTAK
>Mature_135_residues
TSVTIFHNPACGTSRNTLAMIRASGEEPDVIEYLKTPPSREQLIALINAMGVRVRDVLREKGTPYADLGLADPKWTDDQL
IEAMLVYPILINRPIVVTGKGARLCRPSELVLDLLDRPVSSFTKEDGEVVSWTAK

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=132, Percent_Identity=62.1212121212121, Blast_Score=170, Evalue=3e-44,
Organism=Escherichia coli, GI1788841, Length=115, Percent_Identity=40.8695652173913, Blast_Score=93, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 15036; Mature: 14904

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVTIFHNPACGTSRNTLAMIRASGEEPDVIEYLKTPPSREQLIALINAMGVRVRDVLR
CCEEEEEECCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHH
EKGTPYADLGLADPKWTDDQLIEAMLVYPILINRPIVVTGKGARLCRPSELVLDLLDRPV
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHCCH
SSFTKEDGEVVSWTAK
HHHHCCCCCEEEEECC
>Mature Secondary Structure 
TSVTIFHNPACGTSRNTLAMIRASGEEPDVIEYLKTPPSREQLIALINAMGVRVRDVLR
CEEEEEECCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHH
EKGTPYADLGLADPKWTDDQLIEAMLVYPILINRPIVVTGKGARLCRPSELVLDLLDRPV
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHCCH
SSFTKEDGEVVSWTAK
HHHHCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3021763; 1703401; 1704144 [H]