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The map label for this gene is yfcG [H]

Identifier: 146340669

GI number: 146340669

Start: 3881736

End: 3882476

Strand: Direct

Name: yfcG [H]

Synonym: BRADO3719

Alternate gene names: 146340669

Gene position: 3881736-3882476 (Clockwise)

Preceding gene: 146340667

Following gene: 146340670

Centisome position: 52.06

GC content: 64.91

Gene sequence:

>741_bases
TTGATGTCTCCACGCAACAGGCGAGCAACAGCCCCCATGTCCGATCTCTCCAGCTTCCCGATCACCCAGCGCTGGCCGGC
GCAGCATCCGGATCGCATCCAGCTCTATTCGCTGCCGACGCCTAACGGCGTGAAGGTCTCGATCATGCTGGAGGAGACGG
GCCTGCCTTACGAGCCGCACACGATCGATTTCGGCAAGGACGACCAGAAGACCCCGGAATTCCTGTCGCTCAATCCGAAT
GGCAAGATCCCCGCGATCATCGATCCGGACGGACCCGGCGGCCAGCCGCTCGGCCTGTTCGAATCCGGCGCGATCCTGCA
ATACCTTGCCGAGAAGACCGGCAAATTCTTGCCCGCCGATCCGGCGCGGCGCTGGCAGACCATCCAATGGGTGCATTTCC
AGATGGGCGGCATCGGGCCGATGTTCGGCCAGCTCGGGTTCTTTCACAAGTTCGCGGGCCGTGAATATGAAGACAAGCGG
CCGTTGCAGCGTTACGTCGCCGAGAGCAAGCGGCTGCTGAGCGTGCTCGAGGCGCGGCTCGGCGGACGCGAGTGGATCAT
GGATCTCGACTACACGATCGCCGACATCGCCAGCCTCGGCTGGGTGCGCAACCTGATCGGCTTTTACGGCGCGCGCGAGC
TGGTGGCGTTCGATGAGCTCAAGCATGTGCCGGCCTGGCTGGAGCGCGGCCTGGCGCGGCCGGCGGTGCAGCGCGGGCTG
GAGATCCCGAAGCGGCCGTGA

Upstream 100 bases:

>100_bases
CACTGCTCATGCTGGATCTCTGCACATGTGCTGCACCACAAGATGATTCCGCCAAGCGAGTTCCCCCTCATGGCTTGCGG
CGGCTCTGCCCTGGCTTAGA

Downstream 100 bases:

>100_bases
TCGTCAGCGAGGCCGATTTCGAGCGCTGTCTCGACGAGGTGCTGTCGGCCCCCGCCGTGGCGGGCGGTGGCGTGGTCGGC
CCCGATAGCATGATGTGGCG

Product: glutathione S-transferase domain-containing protein

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MMSPRNRRATAPMSDLSSFPITQRWPAQHPDRIQLYSLPTPNGVKVSIMLEETGLPYEPHTIDFGKDDQKTPEFLSLNPN
GKIPAIIDPDGPGGQPLGLFESGAILQYLAEKTGKFLPADPARRWQTIQWVHFQMGGIGPMFGQLGFFHKFAGREYEDKR
PLQRYVAESKRLLSVLEARLGGREWIMDLDYTIADIASLGWVRNLIGFYGARELVAFDELKHVPAWLERGLARPAVQRGL
EIPKRP

Sequences:

>Translated_246_residues
MMSPRNRRATAPMSDLSSFPITQRWPAQHPDRIQLYSLPTPNGVKVSIMLEETGLPYEPHTIDFGKDDQKTPEFLSLNPN
GKIPAIIDPDGPGGQPLGLFESGAILQYLAEKTGKFLPADPARRWQTIQWVHFQMGGIGPMFGQLGFFHKFAGREYEDKR
PLQRYVAESKRLLSVLEARLGGREWIMDLDYTIADIASLGWVRNLIGFYGARELVAFDELKHVPAWLERGLARPAVQRGL
EIPKRP
>Mature_246_residues
MMSPRNRRATAPMSDLSSFPITQRWPAQHPDRIQLYSLPTPNGVKVSIMLEETGLPYEPHTIDFGKDDQKTPEFLSLNPN
GKIPAIIDPDGPGGQPLGLFESGAILQYLAEKTGKFLPADPARRWQTIQWVHFQMGGIGPMFGQLGFFHKFAGREYEDKR
PLQRYVAESKRLLSVLEARLGGREWIMDLDYTIADIASLGWVRNLIGFYGARELVAFDELKHVPAWLERGLARPAVQRGL
EIPKRP

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=209, Percent_Identity=44.0191387559809, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI87082195, Length=242, Percent_Identity=39.6694214876033, Blast_Score=148, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6324100, Length=273, Percent_Identity=31.1355311355311, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 27791; Mature: 27791

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSPRNRRATAPMSDLSSFPITQRWPAQHPDRIQLYSLPTPNGVKVSIMLEETGLPYEPH
CCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEEECCCCCCCCC
TIDFGKDDQKTPEFLSLNPNGKIPAIIDPDGPGGQPLGLFESGAILQYLAEKTGKFLPAD
EECCCCCCCCCCCEEEECCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
PARRWQTIQWVHFQMGGIGPMFGQLGFFHKFAGREYEDKRPLQRYVAESKRLLSVLEARL
HHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GGREWIMDLDYTIADIASLGWVRNLIGFYGARELVAFDELKHVPAWLERGLARPAVQRGL
CCCCEEEECCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCC
EIPKRP
CCCCCC
>Mature Secondary Structure
MMSPRNRRATAPMSDLSSFPITQRWPAQHPDRIQLYSLPTPNGVKVSIMLEETGLPYEPH
CCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEEECCCCCCCCC
TIDFGKDDQKTPEFLSLNPNGKIPAIIDPDGPGGQPLGLFESGAILQYLAEKTGKFLPAD
EECCCCCCCCCCCEEEECCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
PARRWQTIQWVHFQMGGIGPMFGQLGFFHKFAGREYEDKRPLQRYVAESKRLLSVLEARL
HHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GGREWIMDLDYTIADIASLGWVRNLIGFYGARELVAFDELKHVPAWLERGLARPAVQRGL
CCCCEEEECCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCC
EIPKRP
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]