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The map label for this gene is yafC [C]

Identifier: 146340660

GI number: 146340660

Start: 3871598

End: 3872509

Strand: Direct

Name: yafC [C]

Synonym: BRADO3708

Alternate gene names: 146340660

Gene position: 3871598-3872509 (Clockwise)

Preceding gene: 146340655

Following gene: 146340661

Centisome position: 51.92

GC content: 69.41

Gene sequence:

>912_bases
ATGGACCTGCTTGGACCGATGCGGACCTTCGTGCGGGTGGTGGAGGCCGGCAGCTTCACCGCCGTCGCCGACGAGTTGAA
CACCACGCAGCCGACCATCAGCCGCCAGATCGGCGCGCTGGAGGAGCATCTGCGCACCCGCCTGTTCACGCGGACGACCC
GGGCGCTGACGCTGACCGACGACGGCCGGGTGTTCTACGAGCACGCGCTGCGGGCGCTGGAGGCGGTGTCGGAGGCGGAG
GGCGCCGTCGGACGCCGCCGGCAGAAGCCCTCCGGGCTGTTGCGGCTGGCGGCGCCGGTGGTGTTCGGGCGGCTGCATGT
GGTGCCGCGGCTGCCGGCGTTCCTGAAGCGCTATCCCGACGTGTCGATCGATCTGATCATGAGCGACGGCTTCGCCGATC
TGGTGGAGCAGGGCATCGACGTCGCCATCCGTGTCGGCGACATCACGGATCCCGGCCTGATCGCGCGGCGCATCGGCACG
GTGCAGCGGGTGACGGTGGCTTCGCCCGCCTATCTCAAGGCACATCGCGCGCCCAAGGTGCCGGCCGATCTCGCCTTGCA
TCAGTGCATCGTCTACTCCAGGCTCGCCACCGGCAATCGGTGGCTGTTCGAGAGCAAGGACGGGCCCGTCGCGGTCGAGG
TGAGCGGGCGCTACCGCGCCGACAATTCGGAGGCTGTGCGCGACGGCGTGCTCGGCGGGCTCGGCATCGCCGTGATCCCG
ACCTTCGCCTTCGTCAGGGAGATCGAAAGCGGCGCGGTGAAGGTGCTGCTGCAAGACTACGCGCCGCGGCCGCTGCCGAT
GCACGCGGTCTACGCCTCGCGCCGCTTCGTGCCGCTGAAGGTGCGCGCCATCATCGATCATCTCGCGCACGAATTCTCGC
TCGATGCGCGGTTGTCGTCCTACACGGCGTGA

Upstream 100 bases:

>100_bases
GCCGGCCGTTGCTGATGGGAGGAGCATGGCTCATTCGGTGCCCTTGGATAATTCTCGTCGGATCGATATCATTCATACGT
TTTGTGTATGAGAGGCAGCG

Downstream 100 bases:

>100_bases
TGTCGCAGCCTTGCAGCATGGAACGGCCGTGCTGCGCCATGCGTTCGACCTGGAGCGGCCGGCGTCGCCGGTGACAAGCC
AGGAGAGACGGGAATGGAAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MDLLGPMRTFVRVVEAGSFTAVADELNTTQPTISRQIGALEEHLRTRLFTRTTRALTLTDDGRVFYEHALRALEAVSEAE
GAVGRRRQKPSGLLRLAAPVVFGRLHVVPRLPAFLKRYPDVSIDLIMSDGFADLVEQGIDVAIRVGDITDPGLIARRIGT
VQRVTVASPAYLKAHRAPKVPADLALHQCIVYSRLATGNRWLFESKDGPVAVEVSGRYRADNSEAVRDGVLGGLGIAVIP
TFAFVREIESGAVKVLLQDYAPRPLPMHAVYASRRFVPLKVRAIIDHLAHEFSLDARLSSYTA

Sequences:

>Translated_303_residues
MDLLGPMRTFVRVVEAGSFTAVADELNTTQPTISRQIGALEEHLRTRLFTRTTRALTLTDDGRVFYEHALRALEAVSEAE
GAVGRRRQKPSGLLRLAAPVVFGRLHVVPRLPAFLKRYPDVSIDLIMSDGFADLVEQGIDVAIRVGDITDPGLIARRIGT
VQRVTVASPAYLKAHRAPKVPADLALHQCIVYSRLATGNRWLFESKDGPVAVEVSGRYRADNSEAVRDGVLGGLGIAVIP
TFAFVREIESGAVKVLLQDYAPRPLPMHAVYASRRFVPLKVRAIIDHLAHEFSLDARLSSYTA
>Mature_303_residues
MDLLGPMRTFVRVVEAGSFTAVADELNTTQPTISRQIGALEEHLRTRLFTRTTRALTLTDDGRVFYEHALRALEAVSEAE
GAVGRRRQKPSGLLRLAAPVVFGRLHVVPRLPAFLKRYPDVSIDLIMSDGFADLVEQGIDVAIRVGDITDPGLIARRIGT
VQRVTVASPAYLKAHRAPKVPADLALHQCIVYSRLATGNRWLFESKDGPVAVEVSGRYRADNSEAVRDGVLGGLGIAVIP
TFAFVREIESGAVKVLLQDYAPRPLPMHAVYASRRFVPLKVRAIIDHLAHEFSLDARLSSYTA

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=285, Percent_Identity=35.4385964912281, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1789639, Length=292, Percent_Identity=31.5068493150685, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI87081978, Length=292, Percent_Identity=35.958904109589, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1787128, Length=283, Percent_Identity=30.0353356890459, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI145693193, Length=291, Percent_Identity=32.9896907216495, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1789440, Length=284, Percent_Identity=29.5774647887324, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787589, Length=289, Percent_Identity=28.719723183391, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1789173, Length=257, Percent_Identity=28.4046692607004, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788706, Length=240, Percent_Identity=25.8333333333333, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI157672245, Length=189, Percent_Identity=32.8042328042328, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786448, Length=253, Percent_Identity=28.0632411067194, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI87082132, Length=262, Percent_Identity=26.7175572519084, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788297, Length=141, Percent_Identity=31.9148936170213, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788748, Length=254, Percent_Identity=26.3779527559055, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790011, Length=283, Percent_Identity=22.9681978798587, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI145693105, Length=253, Percent_Identity=26.0869565217391, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787601, Length=120, Percent_Identity=30.8333333333333, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1787879, Length=144, Percent_Identity=32.6388888888889, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33268; Mature: 33268

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLGPMRTFVRVVEAGSFTAVADELNTTQPTISRQIGALEEHLRTRLFTRTTRALTLTD
CCCCHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEEEC
DGRVFYEHALRALEAVSEAEGAVGRRRQKPSGLLRLAAPVVFGRLHVVPRLPAFLKRYPD
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCC
VSIDLIMSDGFADLVEQGIDVAIRVGDITDPGLIARRIGTVQRVTVASPAYLKAHRAPKV
CEEEEEECCCHHHHHHCCCEEEEEECCCCCHHHHHHHHCCHHEEEECCCHHHHHCCCCCC
PADLALHQCIVYSRLATGNRWLFESKDGPVAVEVSGRYRADNSEAVRDGVLGGLGIAVIP
CHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCEECCCHHHHHHHHHHCHHHHHHH
TFAFVREIESGAVKVLLQDYAPRPLPMHAVYASRRFVPLKVRAIIDHLAHEFSLDARLSS
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
YTA
CCC
>Mature Secondary Structure
MDLLGPMRTFVRVVEAGSFTAVADELNTTQPTISRQIGALEEHLRTRLFTRTTRALTLTD
CCCCHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEEEC
DGRVFYEHALRALEAVSEAEGAVGRRRQKPSGLLRLAAPVVFGRLHVVPRLPAFLKRYPD
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCC
VSIDLIMSDGFADLVEQGIDVAIRVGDITDPGLIARRIGTVQRVTVASPAYLKAHRAPKV
CEEEEEECCCHHHHHHCCCEEEEEECCCCCHHHHHHHHCCHHEEEECCCHHHHHCCCCCC
PADLALHQCIVYSRLATGNRWLFESKDGPVAVEVSGRYRADNSEAVRDGVLGGLGIAVIP
CHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCEECCCHHHHHHHHHHCHHHHHHH
TFAFVREIESGAVKVLLQDYAPRPLPMHAVYASRRFVPLKVRAIIDHLAHEFSLDARLSS
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
YTA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]