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The map label for this gene is prsW [H]

Identifier: 146340549

GI number: 146340549

Start: 3783881

End: 3784909

Strand: Reverse

Name: prsW [H]

Synonym: BRADO3592

Alternate gene names: 146340549

Gene position: 3784909-3783881 (Counterclockwise)

Preceding gene: 146340553

Following gene: 146340548

Centisome position: 50.76

GC content: 67.35

Gene sequence:

>1029_bases
ATGGCCTACCTGCCGTCGCAAATGAACCTGCTCGAAGCGCTCGCGACAGTGGTCGGAACCGCAGCGATTGCACCCGCGCT
CCTGATCCTGTGGCTGGTGGTCGCTGCTGGCGACAATTCCGGTCCGCCGCTCAAGATCTGGACCGCCTTCCTGCTCGGCG
CAGCCAGCGTGCTTCTGCTCGGCATCGTCAGGGCGCCGTTCCAGAACGTCGGTCTGGGGATCGAAAATCCCTGGCTCGCG
CAGGCCGTCCGGGCGCTGTTCAGCGTTGCGCTGCCGGAGGAGATCGCCAAGGTCGCGGTGATCGCTGTGCTTTGGTCGCG
GCGCAGGCAGGTCGGCAATGCCATGGACACCGTGTTCTATGGCGCGGCCGTCGGGCTCGGCTTTGCGGCCTATGAGAACC
TCGCTTATCTCGTCCAGCATGCGGAGATGTGGCGCTCGCTGGCGATCCTGCGCAGCGTGCTCACCGTCCCCTTCCACGGC
GCGCTCGGCATCATTGCCGGCGCCTACCTCGCGATCGCCCGCACATCCACCGCGCTCGGTGCGAACCGGCACAATCGCGA
CTGGGCGCGGATGTCGAGCTGGGCGCTGGTGCTGGCGGCGCCCGTGATGCTGCATGCGGCATTCGACTATCCGCTGCTGC
TGCTGCAGCGCGCATCCAACCTCGATCCGACCTCGCGGCTCTGGCTCGGTGCCGTCAGCGTCCTGATCGGCTTCTCGTCG
ATCGCACTCGCGGTGCGGCTGGTGCGCCGCGTCGCCCATCACCACACACCGCGTACCGAGATGGCCAAGGCCCGACTCAG
CCAGCTGCGCCGGATGTGGGCGCTGCTGCTGCTCGGCGGCGCCGCCGGCTTCATCGGTCTCGGCTTCGTGCTGACCTCGG
TCCGGCACTGGCTGCTCAACCCCGATCGCAACATCGCCGGCGTGCTTGTTCCCCTCGGGCTCACCGCGATCGTCCTTGGC
GTGGCCCTCCTGATTGTCACAACGACCATCTATGTGTTCGGCCGCAACCGGATGCGGACCACGGCCTAA

Upstream 100 bases:

>100_bases
CGACATGTAGGTCTTACGCCGCGGTTGCGAACTGATCTTAGACCCAAGCCTCGCGGGAGGTGATGACCGGTTCCGCCAGC
GGCATCGATGATTGGAGACC

Downstream 100 bases:

>100_bases
GGCCCACCGCAGGCCTGGATTGCATTGAAACGCGGCTCGGGCGCTTGTCCGGACCGTGGTTCCACACCATCTGCGTGAGC
AGCAGGCGCCGCGTCCAGCG

Product: hypothetical protein

Products: NA

Alternate protein names: Protease responsible for activating sigma-W [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MAYLPSQMNLLEALATVVGTAAIAPALLILWLVVAAGDNSGPPLKIWTAFLLGAASVLLLGIVRAPFQNVGLGIENPWLA
QAVRALFSVALPEEIAKVAVIAVLWSRRRQVGNAMDTVFYGAAVGLGFAAYENLAYLVQHAEMWRSLAILRSVLTVPFHG
ALGIIAGAYLAIARTSTALGANRHNRDWARMSSWALVLAAPVMLHAAFDYPLLLLQRASNLDPTSRLWLGAVSVLIGFSS
IALAVRLVRRVAHHHTPRTEMAKARLSQLRRMWALLLLGGAAGFIGLGFVLTSVRHWLLNPDRNIAGVLVPLGLTAIVLG
VALLIVTTTIYVFGRNRMRTTA

Sequences:

>Translated_342_residues
MAYLPSQMNLLEALATVVGTAAIAPALLILWLVVAAGDNSGPPLKIWTAFLLGAASVLLLGIVRAPFQNVGLGIENPWLA
QAVRALFSVALPEEIAKVAVIAVLWSRRRQVGNAMDTVFYGAAVGLGFAAYENLAYLVQHAEMWRSLAILRSVLTVPFHG
ALGIIAGAYLAIARTSTALGANRHNRDWARMSSWALVLAAPVMLHAAFDYPLLLLQRASNLDPTSRLWLGAVSVLIGFSS
IALAVRLVRRVAHHHTPRTEMAKARLSQLRRMWALLLLGGAAGFIGLGFVLTSVRHWLLNPDRNIAGVLVPLGLTAIVLG
VALLIVTTTIYVFGRNRMRTTA
>Mature_341_residues
AYLPSQMNLLEALATVVGTAAIAPALLILWLVVAAGDNSGPPLKIWTAFLLGAASVLLLGIVRAPFQNVGLGIENPWLAQ
AVRALFSVALPEEIAKVAVIAVLWSRRRQVGNAMDTVFYGAAVGLGFAAYENLAYLVQHAEMWRSLAILRSVLTVPFHGA
LGIIAGAYLAIARTSTALGANRHNRDWARMSSWALVLAAPVMLHAAFDYPLLLLQRASNLDPTSRLWLGAVSVLIGFSSI
ALAVRLVRRVAHHHTPRTEMAKARLSQLRRMWALLLLGGAAGFIGLGFVLTSVRHWLLNPDRNIAGVLVPLGLTAIVLGV
ALLIVTTTIYVFGRNRMRTTA

Specific function: Is responsible for Site-1 cleavage of the RsiW anti- sigma factor. This results, after two other proteolytic steps catalyzed by the RasP and ClpXP proteases, in the release of SigW and the transcription activation of the genes under the control of the sig

COG id: COG2339

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protease prsW family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 36779; Mature: 36648

Theoretical pI: Translated: 11.83; Mature: 11.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYLPSQMNLLEALATVVGTAAIAPALLILWLVVAAGDNSGPPLKIWTAFLLGAASVLLL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
GIVRAPFQNVGLGIENPWLAQAVRALFSVALPEEIAKVAVIAVLWSRRRQVGNAMDTVFY
HHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAAVGLGFAAYENLAYLVQHAEMWRSLAILRSVLTVPFHGALGIIAGAYLAIARTSTALG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
ANRHNRDWARMSSWALVLAAPVMLHAAFDYPLLLLQRASNLDPTSRLWLGAVSVLIGFSS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
IALAVRLVRRVAHHHTPRTEMAKARLSQLRRMWALLLLGGAAGFIGLGFVLTSVRHWLLN
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PDRNIAGVLVPLGLTAIVLGVALLIVTTTIYVFGRNRMRTTA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AYLPSQMNLLEALATVVGTAAIAPALLILWLVVAAGDNSGPPLKIWTAFLLGAASVLLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH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CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]