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The map label for this gene is yodQ [H]

Identifier: 146340355

GI number: 146340355

Start: 3578602

End: 3579882

Strand: Direct

Name: yodQ [H]

Synonym: BRADO3383

Alternate gene names: 146340355

Gene position: 3578602-3579882 (Clockwise)

Preceding gene: 146340350

Following gene: 146340356

Centisome position: 47.99

GC content: 63.86

Gene sequence:

>1281_bases
ATGATCACTGAGGACATCACGCAACGGATCGTCGACGCCGTCGACACCGGCTTCGGCCGCCAGCTCGAGACCACGAGGGA
CTTCGTTGCGATTCCTTCGACCCGCGGTGCCGAAGGGCCGTGCCAGGACATGTTCGGCGATCTCCTGCGGGCGCGCGGCT
ACGAGGTCGACGACTGGCATATCGAGCTCGACGATCTCAAGGACATGCGCGGCTACGGCCCGATCGAGCACGACTTCTCG
AAGGCGCGAAGCGTGGTTGGAACCTTCAGGCCCGCAACCTCCGCAGGACATTCGCTGATCGTGCAAGGGCATTGCGACGT
CGTGCCGGCGGGCCCGCTCGACATGTGGGAGACGCCGCCGTTCTCACCGGTCATCCGCGATGGCCGGATGTACGGCCGCG
GCGCCTGCGACATGAAGTCCGGCACGATCGGCGCGCTCTATGCGCTCGATGCCATCAAGGCCGCGGGCTATACACCGACC
GCGCGCATCCACCTCCAGTCCGTCATCGAAGAGGAAAGCACCGGCGTCGGCGCGTTGTCGACCTTGCAGCGCGGCTATCG
CGCCGATGCCTGCTTCATCCCGGAACCGACCGGCGGCAAGATGGTGCGGTCGCAGGTCGGCGTGATCTGGTTCCGCATCA
AGGTCCGCGGCTTTCCGGCGCATGTGTTCGAGGCCGGCATCGGCGCCAATGCGATCCAGGCGACCTATCATTTGATTCAC
GCGCTGGAGAAGCTGGAAGCGGACTGGAACGAGCGCGCGAAGAGCGACCGGCATTTCAAGACGCTCGATCACCCGATCAA
CTTCAATCCGGGCATCATCAAGGGCGGCGACTGGGCCTCGAGCGTGCCGGCGTGGTGCGACGTCGATTGCCGAATTGCGA
TCCTGCCCGGTTGGTCGGTCAAGGACTGCCAGAACGAGATTCTCGCCTGCGTCGGCGCCGCCTCGCGTGACCATCGTTTC
CTGTCCAACAATCCACCGGTGATCGAATGGTCCGGCTTCCTGTCGGAAGGTTATGAGCTGACCAACTCCGCCGAGCCGGA
GGCTGCGTTCGGCAAGGCCTTCAATGCGGTGTATGGCGGCGCGGTGCAGGATCTCGTCTTCACCGCGCTGACCGATACGC
GGTTCTACGGCCTCAACTACAACATCCCGAGCCTGTGTTTCGGGGCGACCGGTGCCGCGATGCACGGGTTCAACGAATAT
GTCGAGCTGGACTCGCTGCGCCAAGTGACCAAGACCATGGCGCTGTTCATTGCTGAATGGTGCGGTGTCGAGAAGGCCTG
A

Upstream 100 bases:

>100_bases
TACGGTGCGGTCTGCGATTCTGAAAGCAGTGGCGAATCCGGTGCACTTATGTAGCAGAGTGTGATTTGCTGAGTCGCCAG
TAACTGGGACCTGTACAGGC

Downstream 100 bases:

>100_bases
GCGGCGAGGATCGGACTGTGGGCGATGACCTCGCAGGTCATTGCCGTTGCTCCATCTCGCGTCCAGATGCGGGGCAGACA
CGCAGAAGACGTGTCGCCGG

Product: acetylornithine deacetylase

Products: acetate; L-ornithine

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MITEDITQRIVDAVDTGFGRQLETTRDFVAIPSTRGAEGPCQDMFGDLLRARGYEVDDWHIELDDLKDMRGYGPIEHDFS
KARSVVGTFRPATSAGHSLIVQGHCDVVPAGPLDMWETPPFSPVIRDGRMYGRGACDMKSGTIGALYALDAIKAAGYTPT
ARIHLQSVIEEESTGVGALSTLQRGYRADACFIPEPTGGKMVRSQVGVIWFRIKVRGFPAHVFEAGIGANAIQATYHLIH
ALEKLEADWNERAKSDRHFKTLDHPINFNPGIIKGGDWASSVPAWCDVDCRIAILPGWSVKDCQNEILACVGAASRDHRF
LSNNPPVIEWSGFLSEGYELTNSAEPEAAFGKAFNAVYGGAVQDLVFTALTDTRFYGLNYNIPSLCFGATGAAMHGFNEY
VELDSLRQVTKTMALFIAEWCGVEKA

Sequences:

>Translated_426_residues
MITEDITQRIVDAVDTGFGRQLETTRDFVAIPSTRGAEGPCQDMFGDLLRARGYEVDDWHIELDDLKDMRGYGPIEHDFS
KARSVVGTFRPATSAGHSLIVQGHCDVVPAGPLDMWETPPFSPVIRDGRMYGRGACDMKSGTIGALYALDAIKAAGYTPT
ARIHLQSVIEEESTGVGALSTLQRGYRADACFIPEPTGGKMVRSQVGVIWFRIKVRGFPAHVFEAGIGANAIQATYHLIH
ALEKLEADWNERAKSDRHFKTLDHPINFNPGIIKGGDWASSVPAWCDVDCRIAILPGWSVKDCQNEILACVGAASRDHRF
LSNNPPVIEWSGFLSEGYELTNSAEPEAAFGKAFNAVYGGAVQDLVFTALTDTRFYGLNYNIPSLCFGATGAAMHGFNEY
VELDSLRQVTKTMALFIAEWCGVEKA
>Mature_426_residues
MITEDITQRIVDAVDTGFGRQLETTRDFVAIPSTRGAEGPCQDMFGDLLRARGYEVDDWHIELDDLKDMRGYGPIEHDFS
KARSVVGTFRPATSAGHSLIVQGHCDVVPAGPLDMWETPPFSPVIRDGRMYGRGACDMKSGTIGALYALDAIKAAGYTPT
ARIHLQSVIEEESTGVGALSTLQRGYRADACFIPEPTGGKMVRSQVGVIWFRIKVRGFPAHVFEAGIGANAIQATYHLIH
ALEKLEADWNERAKSDRHFKTLDHPINFNPGIIKGGDWASSVPAWCDVDCRIAILPGWSVKDCQNEILACVGAASRDHRF
LSNNPPVIEWSGFLSEGYELTNSAEPEAAFGKAFNAVYGGAVQDLVFTALTDTRFYGLNYNIPSLCFGATGAAMHGFNEY
VELDSLRQVTKTMALFIAEWCGVEKA

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=296, Percent_Identity=26.3513513513513, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788816, Length=237, Percent_Identity=27.0042194092827, Blast_Score=82, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010182
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: 3.5.1.16

Molecular weight: Translated: 46620; Mature: 46620

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITEDITQRIVDAVDTGFGRQLETTRDFVAIPSTRGAEGPCQDMFGDLLRARGYEVDDWH
CCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCEE
IELDDLKDMRGYGPIEHDFSKARSVVGTFRPATSAGHSLIVQGHCDVVPAGPLDMWETPP
EEHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEECCCCCCCCCCCC
FSPVIRDGRMYGRGACDMKSGTIGALYALDAIKAAGYTPTARIHLQSVIEEESTGVGALS
CCHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHH
TLQRGYRADACFIPEPTGGKMVRSQVGVIWFRIKVRGFPAHVFEAGIGANAIQATYHLIH
HHHHCCCCCEEECCCCCCCHHHHHCCCEEEEEEEEECCCHHHHHHCCCCHHHHHHHHHHH
ALEKLEADWNERAKSDRHFKTLDHPINFNPGIIKGGDWASSVPAWCDVDCRIAILPGWSV
HHHHHHCCHHHHHCCCCCHHHCCCCCCCCCCEEECCCCCCCCCCEECCCEEEEEECCCCH
KDCQNEILACVGAASRDHRFLSNNPPVIEWSGFLSEGYELTNSAEPEAAFGKAFNAVYGG
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHCCEECCCCCCCCHHHHHHHHHHHCH
AVQDLVFTALTDTRFYGLNYNIPSLCFGATGAAMHGFNEYVELDSLRQVTKTMALFIAEW
HHHHHHHHHHHCCEEEECCCCCCHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
CGVEKA
HCCCCC
>Mature Secondary Structure
MITEDITQRIVDAVDTGFGRQLETTRDFVAIPSTRGAEGPCQDMFGDLLRARGYEVDDWH
CCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCEE
IELDDLKDMRGYGPIEHDFSKARSVVGTFRPATSAGHSLIVQGHCDVVPAGPLDMWETPP
EEHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEECCCCCCCCCCCC
FSPVIRDGRMYGRGACDMKSGTIGALYALDAIKAAGYTPTARIHLQSVIEEESTGVGALS
CCHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHH
TLQRGYRADACFIPEPTGGKMVRSQVGVIWFRIKVRGFPAHVFEAGIGANAIQATYHLIH
HHHHCCCCCEEECCCCCCCHHHHHCCCEEEEEEEEECCCHHHHHHCCCCHHHHHHHHHHH
ALEKLEADWNERAKSDRHFKTLDHPINFNPGIIKGGDWASSVPAWCDVDCRIAILPGWSV
HHHHHHCCHHHHHCCCCCHHHCCCCCCCCCCEEECCCCCCCCCCEECCCEEEEEECCCCH
KDCQNEILACVGAASRDHRFLSNNPPVIEWSGFLSEGYELTNSAEPEAAFGKAFNAVYGG
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHCCEECCCCCCCCHHHHHHHHHHHCH
AVQDLVFTALTDTRFYGLNYNIPSLCFGATGAAMHGFNEYVELDSLRQVTKTMALFIAEW
HHHHHHHHHHHCCEEEECCCCCCHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
CGVEKA
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Glutathione. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N2-acetyl-L-ornithine; H2O

Specific reaction: N2-acetyl-L-ornithine + H2O = acetate + L-ornithine

General reaction: Carboxylic acid amide hydrolysis [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377 [H]