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The map label for this gene is actIII [H]

Identifier: 146339928

GI number: 146339928

Start: 3138545

End: 3139276

Strand: Reverse

Name: actIII [H]

Synonym: BRADO2932

Alternate gene names: 146339928

Gene position: 3139276-3138545 (Counterclockwise)

Preceding gene: 146339929

Following gene: 146339922

Centisome position: 42.1

GC content: 70.08

Gene sequence:

>732_bases
ATGGACGCATCTGTTTCCCTCGCCCTCATCACCGGCGCCGGACGCGCCACCGGTATCGGCTTCGAGGTGGCACGGCAGCT
CGGCCAGCGCGGCTTTCACATCATCCTGACCGCTCGCAAGGCGGCGGACGCACGGGCAAGAGCGGATGAACTCAGCGCCA
TGGCCGTGAGGGCGGAGGGGCACGGCATGGACATCACCGATCCCGACGCCACCGCGAAGCTTGCCGCGCTGCTCGATGAG
CGGTTCGGCCGGCTCGACGTGCTGGTCAACAACGCGGCGACGCTCGGCCGTTACGACGAGACCGCCTCGAACGCCGATCT
CGGCGAGGTCCGCGCCAATTTCGAGAGCACGCTGTTCGGCGCCTGGGCGGTCGCGCAGACGTTTCTGCCGCTGTTGCGCA
ACAGCGCGCATGGCCGGCTGGTCAATGTGTCCAGCGGCGCCGGCTCGCACAGCGACCCGGAATTCGGTCTCGCCACCGCG
GCGCCGATGCCGGCCTCCTACGGAGTTGCCAAGGCTGCGCTGAATGCCCTGACGGTGAAACTCGCCAGAGAAAACCCCGG
CCTGCGCGTCAACGCCGTCTGCCCCGGCTTCACCGCGACCTTCGATGGCGGCGCCGCAATGGGCGCGCGCCCCGTGGCCG
ACGGGGCCGCCAGCGTGATGTGGGCCGCGCTGCTCGACGATGACGGCCCGACCGGCGGCTTCTTCCGCGACGGCAAGCCG
CTCGGCTGGTAG

Upstream 100 bases:

>100_bases
CCGGAGCGAGCCAATACTTGCCGACAGGCCGATCCGCCCAAGTCGGCACAGCGTTTCCGGATCAACGTCATCCCATGCAT
TGAGACCAGCGAGACGATCC

Downstream 100 bases:

>100_bases
CATCGGATCAACGGCGGGCGACTGACCTCTGCTAGTCAAGCTAGAAGGGCTTGCTGCGACATATCGCACGCGCAATATCG
ATAGCAGGGTATCAGGCGCC

Product: putative short chain oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MDASVSLALITGAGRATGIGFEVARQLGQRGFHIILTARKAADARARADELSAMAVRAEGHGMDITDPDATAKLAALLDE
RFGRLDVLVNNAATLGRYDETASNADLGEVRANFESTLFGAWAVAQTFLPLLRNSAHGRLVNVSSGAGSHSDPEFGLATA
APMPASYGVAKAALNALTVKLARENPGLRVNAVCPGFTATFDGGAAMGARPVADGAASVMWAALLDDDGPTGGFFRDGKP
LGW

Sequences:

>Translated_243_residues
MDASVSLALITGAGRATGIGFEVARQLGQRGFHIILTARKAADARARADELSAMAVRAEGHGMDITDPDATAKLAALLDE
RFGRLDVLVNNAATLGRYDETASNADLGEVRANFESTLFGAWAVAQTFLPLLRNSAHGRLVNVSSGAGSHSDPEFGLATA
APMPASYGVAKAALNALTVKLARENPGLRVNAVCPGFTATFDGGAAMGARPVADGAASVMWAALLDDDGPTGGFFRDGKP
LGW
>Mature_243_residues
MDASVSLALITGAGRATGIGFEVARQLGQRGFHIILTARKAADARARADELSAMAVRAEGHGMDITDPDATAKLAALLDE
RFGRLDVLVNNAATLGRYDETASNADLGEVRANFESTLFGAWAVAQTFLPLLRNSAHGRLVNVSSGAGSHSDPEFGLATA
APMPASYGVAKAALNALTVKLARENPGLRVNAVCPGFTATFDGGAAMGARPVADGAASVMWAALLDDDGPTGGFFRDGKP
LGW

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4502601, Length=286, Percent_Identity=30.0699300699301, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI87082100, Length=198, Percent_Identity=33.8383838383838, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787335, Length=207, Percent_Identity=30.4347826086957, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790717, Length=193, Percent_Identity=29.0155440414508, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788459, Length=202, Percent_Identity=33.1683168316832, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI72001658, Length=238, Percent_Identity=30.2521008403361, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=198, Percent_Identity=29.2929292929293, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=215, Percent_Identity=30.2325581395349, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=210, Percent_Identity=29.5238095238095, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=217, Percent_Identity=30.8755760368664, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6322227, Length=201, Percent_Identity=29.3532338308458, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI23397609, Length=205, Percent_Identity=34.6341463414634, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21355319, Length=191, Percent_Identity=28.2722513089005, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25038; Mature: 25038

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDASVSLALITGAGRATGIGFEVARQLGQRGFHIILTARKAADARARADELSAMAVRAEG
CCCCEEEEEEECCCCCCCCCHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHEEEEEECC
HGMDITDPDATAKLAALLDERFGRLDVLVNNAATLGRYDETASNADLGEVRANFESTLFG
CCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCHHCCCCCCCCCCCCHHHHHHHHHHHHHH
AWAVAQTFLPLLRNSAHGRLVNVSSGAGSHSDPEFGLATAAPMPASYGVAKAALNALTVK
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHEEE
LARENPGLRVNAVCPGFTATFDGGAAMGARPVADGAASVMWAALLDDDGPTGGFFRDGKP
EECCCCCEEEEEECCCCEEECCCCCCCCCCCCCCHHHHHHHHEEECCCCCCCCCCCCCCC
LGW
CCC
>Mature Secondary Structure
MDASVSLALITGAGRATGIGFEVARQLGQRGFHIILTARKAADARARADELSAMAVRAEG
CCCCEEEEEEECCCCCCCCCHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHEEEEEECC
HGMDITDPDATAKLAALLDERFGRLDVLVNNAATLGRYDETASNADLGEVRANFESTLFG
CCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCHHCCCCCCCCCCCCHHHHHHHHHHHHHH
AWAVAQTFLPLLRNSAHGRLVNVSSGAGSHSDPEFGLATAAPMPASYGVAKAALNALTVK
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHEEE
LARENPGLRVNAVCPGFTATFDGGAAMGARPVADGAASVMWAALLDDDGPTGGFFRDGKP
EECCCCCEEEEEECCCCEEECCCCCCCCCCCCCCHHHHHHHHEEECCCCCCCCCCCCCCC
LGW
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2469622; 12000953 [H]