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The map label for this gene is paaG [C]

Identifier: 146339911

GI number: 146339911

Start: 3114445

End: 3115335

Strand: Reverse

Name: paaG [C]

Synonym: BRADO2915

Alternate gene names: 146339911

Gene position: 3115335-3114445 (Counterclockwise)

Preceding gene: 146339912

Following gene: 146339907

Centisome position: 41.78

GC content: 67.0

Gene sequence:

>891_bases
ATGACCTACCAGACCATCCTCTACGACGTCGCCGACAAGATCCTCACCATCACGCTGAATCGCCCCGAGAAGCTCAACGC
CTTCACCGGCACGATGATGGAAGAGCTCATCGACGCCTTCGACCGCGCCGACAAGGATGACGGCGTCAGGGCGATCATCG
TCACCGGGGCCGGCCGCGCCTTCTGCGCCGGCGCCGATCTCTCCTCCGGTGCCGACACGTTCGACCGCGATGCCAAGCGC
GGGCCGGTGAAGCGGTACGCCGACGGCCGCGTCGACTATTCCGATCCGCAGGTGCGCGACGGCGGCGGCCAGGTGACGCT
GCGCATCTTCAAGTCTCTGAAGCCTGTGATCGCGGCCGTGAACGGCCCGGCCGTCGGCATCGGCGTCACCATGCAGCTCG
CGATGGACATCCGCATTGCGTCCGAGGCGGCGCGGTTCGGCTTCGTGTTCTCCCAGCGCGGCATCGTGCCCGAGGCGGCG
TCGAGCTGGTTCCTGCCGCGCATCGTCGGCATCTCGCAGGCGCTGGAATGGTGCTACACCGGCCGCGTCTTCCCGGCGCA
GGAGGCGCTCGCCGGCCGCCTCGTCAGCAAGGTCGTGCCGCCGGACGAACTGCTGCCGACCGCCCGCGCGCTGGCGCGCG
AGATCGCCGACAAGACCGCACCGGTCTCGATCGCGCTGATCCGCCAGATGATGTGGCGCATGATGGGATCAGACGATCCG
ATGGAGGCCCACAAGGTCGACAGCCGCGGCATCTATGCGCGGGGCCGCTCGGATGACGTCAAGGAAGGCGTGGTGTCGTT
CCTGGAGAAGCGTCCGGCACAGTTCAAGAACACGGTAACGAAGGATATGCCGGACTACTTCCCGTGGTGGGACGAGCGCG
AGTACAAGTAG

Upstream 100 bases:

>100_bases
ATGTCGCACGCCCATTGCCGCGTCGTATGGGTCTAAGCTTGCGCATCGACGTGGAATGACGTTTTTAACAACGAGAACAA
CAATACATTGGGAAACGCTC

Downstream 100 bases:

>100_bases
TGTCCGAGTGCGCACGCACGACATCCTCGGCTGTCGTCCCGGCCTTGAGCCGGGACCCATAGCCACCGGCTCGGGTTTGG
CGAAGAACGACGTTCAGGGT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MTYQTILYDVADKILTITLNRPEKLNAFTGTMMEELIDAFDRADKDDGVRAIIVTGAGRAFCAGADLSSGADTFDRDAKR
GPVKRYADGRVDYSDPQVRDGGGQVTLRIFKSLKPVIAAVNGPAVGIGVTMQLAMDIRIASEAARFGFVFSQRGIVPEAA
SSWFLPRIVGISQALEWCYTGRVFPAQEALAGRLVSKVVPPDELLPTARALAREIADKTAPVSIALIRQMMWRMMGSDDP
MEAHKVDSRGIYARGRSDDVKEGVVSFLEKRPAQFKNTVTKDMPDYFPWWDEREYK

Sequences:

>Translated_296_residues
MTYQTILYDVADKILTITLNRPEKLNAFTGTMMEELIDAFDRADKDDGVRAIIVTGAGRAFCAGADLSSGADTFDRDAKR
GPVKRYADGRVDYSDPQVRDGGGQVTLRIFKSLKPVIAAVNGPAVGIGVTMQLAMDIRIASEAARFGFVFSQRGIVPEAA
SSWFLPRIVGISQALEWCYTGRVFPAQEALAGRLVSKVVPPDELLPTARALAREIADKTAPVSIALIRQMMWRMMGSDDP
MEAHKVDSRGIYARGRSDDVKEGVVSFLEKRPAQFKNTVTKDMPDYFPWWDEREYK
>Mature_295_residues
TYQTILYDVADKILTITLNRPEKLNAFTGTMMEELIDAFDRADKDDGVRAIIVTGAGRAFCAGADLSSGADTFDRDAKRG
PVKRYADGRVDYSDPQVRDGGGQVTLRIFKSLKPVIAAVNGPAVGIGVTMQLAMDIRIASEAARFGFVFSQRGIVPEAAS
SWFLPRIVGISQALEWCYTGRVFPAQEALAGRLVSKVVPPDELLPTARALAREIADKTAPVSIALIRQMMWRMMGSDDPM
EAHKVDSRGIYARGRSDDVKEGVVSFLEKRPAQFKNTVTKDMPDYFPWWDEREYK

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=264, Percent_Identity=33.3333333333333, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI45643119, Length=279, Percent_Identity=29.0322580645161, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI260275230, Length=279, Percent_Identity=29.0322580645161, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI260274832, Length=279, Percent_Identity=29.0322580645161, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI70995211, Length=238, Percent_Identity=32.7731092436975, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI31542718, Length=264, Percent_Identity=30.3030303030303, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI116235487, Length=209, Percent_Identity=30.622009569378, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI4757968, Length=199, Percent_Identity=27.6381909547739, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI49355787, Length=199, Percent_Identity=27.6381909547739, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4757966, Length=198, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI51538581, Length=198, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI25453481, Length=198, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI51538573, Length=198, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI221307494, Length=233, Percent_Identity=29.1845493562232, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI221136756, Length=233, Percent_Identity=29.1845493562232, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI221136753, Length=233, Percent_Identity=29.1845493562232, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI68989263, Length=214, Percent_Identity=29.4392523364486, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4502327, Length=275, Percent_Identity=29.8181818181818, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1787660, Length=278, Percent_Identity=35.9712230215827, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1787659, Length=266, Percent_Identity=30.8270676691729, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI221142681, Length=263, Percent_Identity=34.2205323193916, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI87082183, Length=290, Percent_Identity=28.9655172413793, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1788597, Length=228, Percent_Identity=30.7017543859649, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788682, Length=247, Percent_Identity=25.5060728744939, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790281, Length=205, Percent_Identity=26.8292682926829, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17554946, Length=266, Percent_Identity=33.0827067669173, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17549921, Length=261, Percent_Identity=30.6513409961686, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI25145438, Length=275, Percent_Identity=32, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17535521, Length=265, Percent_Identity=28.3018867924528, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17560910, Length=204, Percent_Identity=32.3529411764706, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17536985, Length=271, Percent_Identity=27.3062730627306, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17540714, Length=210, Percent_Identity=30.952380952381, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17534483, Length=222, Percent_Identity=29.2792792792793, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17540306, Length=276, Percent_Identity=24.2753623188406, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25141363, Length=186, Percent_Identity=27.9569892473118, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=226, Percent_Identity=28.3185840707965, Blast_Score=90, Evalue=4e-19,
Organism=Drosophila melanogaster, GI20129971, Length=264, Percent_Identity=34.8484848484849, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24653477, Length=264, Percent_Identity=34.8484848484849, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24654903, Length=207, Percent_Identity=31.8840579710145, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24653139, Length=267, Percent_Identity=30.3370786516854, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI19920382, Length=221, Percent_Identity=32.1266968325792, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357171, Length=213, Percent_Identity=28.6384976525822, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24650670, Length=216, Percent_Identity=28.7037037037037, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI19922422, Length=277, Percent_Identity=23.4657039711191, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 32750; Mature: 32619

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYQTILYDVADKILTITLNRPEKLNAFTGTMMEELIDAFDRADKDDGVRAIIVTGAGRA
CCHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCE
FCAGADLSSGADTFDRDAKRGPVKRYADGRVDYSDPQVRDGGGQVTLRIFKSLKPVIAAV
EEECCCCCCCCCHHHHHHHCCCHHHHCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHC
NGPAVGIGVTMQLAMDIRIASEAARFGFVFSQRGIVPEAASSWFLPRIVGISQALEWCYT
CCCEEEHHHEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GRVFPAQEALAGRLVSKVVPPDELLPTARALAREIADKTAPVSIALIRQMMWRMMGSDDP
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
MEAHKVDSRGIYARGRSDDVKEGVVSFLEKRPAQFKNTVTKDMPDYFPWWDEREYK
CHHHHCCCCCEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TYQTILYDVADKILTITLNRPEKLNAFTGTMMEELIDAFDRADKDDGVRAIIVTGAGRA
CHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCE
FCAGADLSSGADTFDRDAKRGPVKRYADGRVDYSDPQVRDGGGQVTLRIFKSLKPVIAAV
EEECCCCCCCCCHHHHHHHCCCHHHHCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHC
NGPAVGIGVTMQLAMDIRIASEAARFGFVFSQRGIVPEAASSWFLPRIVGISQALEWCYT
CCCEEEHHHEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GRVFPAQEALAGRLVSKVVPPDELLPTARALAREIADKTAPVSIALIRQMMWRMMGSDDP
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
MEAHKVDSRGIYARGRSDDVKEGVVSFLEKRPAQFKNTVTKDMPDYFPWWDEREYK
CHHHHCCCCCEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA