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The map label for this gene is gpt [H]

Identifier: 146339905

GI number: 146339905

Start: 3109058

End: 3109579

Strand: Direct

Name: gpt [H]

Synonym: BRADO2909

Alternate gene names: 146339905

Gene position: 3109058-3109579 (Clockwise)

Preceding gene: 146339904

Following gene: 146339906

Centisome position: 41.7

GC content: 67.62

Gene sequence:

>522_bases
ATGACGGACAAGACGTTGACGGCAGAGGAGCGGGCGGGGCGGGCCTTCCCGGTGTCCTGGGATCAGTTTCACAGGGATTG
CCGGGCGCTGACCTGGCGGCTGAACGATGCCGGCCCGTTCGGCGCGATCATCGCGATCACCCGCGGCGGGCTGGTGCCCG
CCGCGATCGTCGCGCGCGAGCTCGGCATCCGCGTGATCGATACGGTCGGCATCGCCAGCTATGACCACACCCGGCAGGGC
GAACTGAACGTGCTGAAGGCGATCTCGGAAGACACGCTGAAGCTCGGCAGCGGCACGGGCAAGGGGCTCTTGATCGTCGA
CGACCTCGTCGACACCGGCAAGACCGCGCAGCTGGTCCGGGAGATGCTGCCCGACGCGCATTTCGCCACCGTTTACGCCA
AGCCGAAGGGCCGTCCGCTGGTCGATACCTTCATCACCGAGGTGTCGCAGGACACCTGGATCTTCTTTCCCTGGGACACC
GCCCTGTCGTTCGCGCCGCCGCTGCGCGACGGAGCGGCCTAG

Upstream 100 bases:

>100_bases
CAGAAGCTGTCGGCGGCGATGAGCGCGGTGAAGGAGATGCTCGCGGGGCTGAACGTGACGCGGTAAAGCAGGTCTGGATT
TCGAGAACGGACGGGGCGAG

Downstream 100 bases:

>100_bases
GCCGACGTCGTCATTGCGAGCGAACCGACGTGTCCGCCATAGCTCGAAGGCCGACGGCGGAAGCAATCCAAGGCTGTGGA
CGGGACTCTGGATTGTTCGT

Product: xanthine-guanine phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT [H]

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MTDKTLTAEERAGRAFPVSWDQFHRDCRALTWRLNDAGPFGAIIAITRGGLVPAAIVARELGIRVIDTVGIASYDHTRQG
ELNVLKAISEDTLKLGSGTGKGLLIVDDLVDTGKTAQLVREMLPDAHFATVYAKPKGRPLVDTFITEVSQDTWIFFPWDT
ALSFAPPLRDGAA

Sequences:

>Translated_173_residues
MTDKTLTAEERAGRAFPVSWDQFHRDCRALTWRLNDAGPFGAIIAITRGGLVPAAIVARELGIRVIDTVGIASYDHTRQG
ELNVLKAISEDTLKLGSGTGKGLLIVDDLVDTGKTAQLVREMLPDAHFATVYAKPKGRPLVDTFITEVSQDTWIFFPWDT
ALSFAPPLRDGAA
>Mature_172_residues
TDKTLTAEERAGRAFPVSWDQFHRDCRALTWRLNDAGPFGAIIAITRGGLVPAAIVARELGIRVIDTVGIASYDHTRQGE
LNVLKAISEDTLKLGSGTGKGLLIVDDLVDTGKTAQLVREMLPDAHFATVYAKPKGRPLVDTFITEVSQDTWIFFPWDTA
LSFAPPLRDGAA

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786433, Length=153, Percent_Identity=50.9803921568627, Blast_Score=161, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 18836; Mature: 18704

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKTLTAEERAGRAFPVSWDQFHRDCRALTWRLNDAGPFGAIIAITRGGLVPAAIVARE
CCCCCCCHHHHCCCCCCCCHHHHHHHHHHEEEEECCCCCCEEEEEEECCCCHHHHHHHHH
LGIRVIDTVGIASYDHTRQGELNVLKAISEDTLKLGSGTGKGLLIVDDLVDTGKTAQLVR
HCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCCEEEEEECCCCCCHHHHHHH
EMLPDAHFATVYAKPKGRPLVDTFITEVSQDTWIFFPWDTALSFAPPLRDGAA
HHCCCCEEEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDKTLTAEERAGRAFPVSWDQFHRDCRALTWRLNDAGPFGAIIAITRGGLVPAAIVARE
CCCCCCHHHHCCCCCCCCHHHHHHHHHHEEEEECCCCCCEEEEEEECCCCHHHHHHHHH
LGIRVIDTVGIASYDHTRQGELNVLKAISEDTLKLGSGTGKGLLIVDDLVDTGKTAQLVR
HCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCCEEEEEECCCCCCHHHHHHH
EMLPDAHFATVYAKPKGRPLVDTFITEVSQDTWIFFPWDTALSFAPPLRDGAA
HHCCCCEEEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]