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The map label for this gene is lepB [H]

Identifier: 146339887

GI number: 146339887

Start: 3090771

End: 3091544

Strand: Direct

Name: lepB [H]

Synonym: BRADO2889

Alternate gene names: 146339887

Gene position: 3090771-3091544 (Clockwise)

Preceding gene: 146339886

Following gene: 146339889

Centisome position: 41.45

GC content: 64.99

Gene sequence:

>774_bases
ATGAGGAGTGCGATGGCGATCCTGGAGGCGCGAGCGATCGGGCCGCGGCGCGAGCCGTGGTGGGCGATCGCTGGAATTTT
CACCGCGGGCTTCGTCCTGCTCTGTCTGCTGCTGGCCTCGCCGGTGCTGATCAGGACCTTCCTCTATCAGCCGTTCAACA
TTCCCGCGCGTTCGATGATGCCGACGTTGCTGACCGGCGACTACGTCTTCGTTTCGAAATACGCCTATGGCTGGGGCCGC
TATACCTGGCCGTTGACGCCGCCGGCCGCGGGGCGCGTCTGGGGCCGCGAGCCGGCGCCAGGCGACGTCGTGGTGTTCCG
CGCCAAGGACGGCAAGACGGATTTCATCAAGCGTGTCGTCGGCGTCGGCGGCGACCGCGTCCAGATGAAGGAGGGCATTC
TCTTCATCAATGACAAGGCGGTGCCGCGCGAACGTCTCCAGGACGTCGTCGGCACCGACGCTTGTGGCGGCGGAGCGACC
GAACGCGTCAAGCGCTGGCGCGAGATCCTGCCGAACGGCGCGAGCTACGAAACGCTGGATTGCGTCGACCATGGCTATTT
CGACAACACCAGCGCATATGTCGTTCCGCCGGGGCATCTGTTCATGCTCGGCGACAACCGGGACAACTCCACCGACAGCC
GAGCTGCAATGGGCTTCATTCCGGTGGAGGACGTGATCGGCCGTGCCGCGATGATCTTTTTCTCCGCTGCGGAGGCCAAA
CAAGGCCAGCCCAGCAGGTTGCGCACCGATCGGATCGGGACGACGGTGCGCTAG

Upstream 100 bases:

>100_bases
GCTCGTCCCCGCATCCCGCGCCGTCATTCCTGAACCCGTCCGTCGAGGGTGATCCATCGCTTGCGCCGCGGCGGGACTTC
GATCATGCTCGGGCGAGGGA

Downstream 100 bases:

>100_bases
GCTAGATCAGCGCGGCGCCGTCGCCGACGATGATCGCGAAGCGATCGGACAATTCGGCGAGCGCGACCTGATGCACCGAC
GCCGCCGGCAGTGTGCCGCC

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MRSAMAILEARAIGPRREPWWAIAGIFTAGFVLLCLLLASPVLIRTFLYQPFNIPARSMMPTLLTGDYVFVSKYAYGWGR
YTWPLTPPAAGRVWGREPAPGDVVVFRAKDGKTDFIKRVVGVGGDRVQMKEGILFINDKAVPRERLQDVVGTDACGGGAT
ERVKRWREILPNGASYETLDCVDHGYFDNTSAYVVPPGHLFMLGDNRDNSTDSRAAMGFIPVEDVIGRAAMIFFSAAEAK
QGQPSRLRTDRIGTTVR

Sequences:

>Translated_257_residues
MRSAMAILEARAIGPRREPWWAIAGIFTAGFVLLCLLLASPVLIRTFLYQPFNIPARSMMPTLLTGDYVFVSKYAYGWGR
YTWPLTPPAAGRVWGREPAPGDVVVFRAKDGKTDFIKRVVGVGGDRVQMKEGILFINDKAVPRERLQDVVGTDACGGGAT
ERVKRWREILPNGASYETLDCVDHGYFDNTSAYVVPPGHLFMLGDNRDNSTDSRAAMGFIPVEDVIGRAAMIFFSAAEAK
QGQPSRLRTDRIGTTVR
>Mature_257_residues
MRSAMAILEARAIGPRREPWWAIAGIFTAGFVLLCLLLASPVLIRTFLYQPFNIPARSMMPTLLTGDYVFVSKYAYGWGR
YTWPLTPPAAGRVWGREPAPGDVVVFRAKDGKTDFIKRVVGVGGDRVQMKEGILFINDKAVPRERLQDVVGTDACGGGAT
ERVKRWREILPNGASYETLDCVDHGYFDNTSAYVVPPGHLFMLGDNRDNSTDSRAAMGFIPVEDVIGRAAMIFFSAAEAK
QGQPSRLRTDRIGTTVR

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=261, Percent_Identity=34.8659003831418, Blast_Score=114, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 28391; Mature: 28391

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSAMAILEARAIGPRREPWWAIAGIFTAGFVLLCLLLASPVLIRTFLYQPFNIPARSMM
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHC
PTLLTGDYVFVSKYAYGWGRYTWPLTPPAAGRVWGREPAPGDVVVFRAKDGKTDFIKRVV
HHHHCCCEEEEEHEECCCCCEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHH
GVGGDRVQMKEGILFINDKAVPRERLQDVVGTDACGGGATERVKRWREILPNGASYETLD
HCCCCEEEEECCEEEEECCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCHH
CVDHGYFDNTSAYVVPPGHLFMLGDNRDNSTDSRAAMGFIPVEDVIGRAAMIFFSAAEAK
HHHCCCCCCCCEEEECCCEEEEEECCCCCCCCCHHEECCCCHHHHHHHHHHHHEEHHHHC
QGQPSRLRTDRIGTTVR
CCCCCHHHHHCCCCCCC
>Mature Secondary Structure
MRSAMAILEARAIGPRREPWWAIAGIFTAGFVLLCLLLASPVLIRTFLYQPFNIPARSMM
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHC
PTLLTGDYVFVSKYAYGWGRYTWPLTPPAAGRVWGREPAPGDVVVFRAKDGKTDFIKRVV
HHHHCCCEEEEEHEECCCCCEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHH
GVGGDRVQMKEGILFINDKAVPRERLQDVVGTDACGGGATERVKRWREILPNGASYETLD
HCCCCEEEEECCEEEEECCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCHH
CVDHGYFDNTSAYVVPPGHLFMLGDNRDNSTDSRAAMGFIPVEDVIGRAAMIFFSAAEAK
HHHCCCCCCCCEEEECCCEEEEEECCCCCCCCCHHEECCCCHHHHHHHHHHHHEEHHHHC
QGQPSRLRTDRIGTTVR
CCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA