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The map label for this gene is coxS [H]

Identifier: 146339855

GI number: 146339855

Start: 3058227

End: 3058712

Strand: Direct

Name: coxS [H]

Synonym: BRADO2857

Alternate gene names: 146339855

Gene position: 3058227-3058712 (Clockwise)

Preceding gene: 146339854

Following gene: 146339856

Centisome position: 41.01

GC content: 63.99

Gene sequence:

>486_bases
ATGGCCAAGATTTCCATGATTGTGAACGGTAATCCCGTCACGGCGAATGTCGACCCGCGGACGCTGCTCGTGCAGTTCCT
GCGCGAAAATCTGCGCCTCACCGGCACCCATGTCGGCTGCGACACCTCGCAATGCGGCGCCTGCGTGGTCCATCTTGACG
GCAAGGCGGTGAAGTCCTGCACGACGCTGGCGGTAATGGCCGACGGCCATGAGGTCCGCACGATCGAGGGGCTCGCCGCC
GACGGCGCGCCGCTGCATCCGATGCAGGAGGCTTTTCGCGAGCATCATGGCCTGCAGTGCGGCTTCTGCACGCCCGGCAT
GATCATGACCGCGGTCGATCTCGTCCACCGCAAGGGCCATGAGCTCAGCGAGGAGACGATTCGCGAGGAGCTAGAGGGCA
ACCTCTGCCGCTGCACCGGTTATCAGAACATCGTGCAGTCCATTGCCGCCGGCGCCAAGGCGATGGCGAAGTCAGACCTC
GCCTAA

Upstream 100 bases:

>100_bases
GGTTGCCCGCCGCCGGGAGCGTCAATATGATGGTTTTCGACCGATTTTTGCTGGGCTGCGCTGCAGTGCAACGCTGTGCG
CGGAATATAGAGAGTCCTGA

Downstream 100 bases:

>100_bases
ACGTCGGACATCGCCTCAGTCGCTCCCGCCGCACGCAGGATATTCTCCCATGTACGAATTCAAATATCACCGGCCGGCCA
CCGTGCGCCAGGCCGCCAAT

Product: putative carbon-monoxide dehydrogenase small subunit, coxS-like protein

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MAKISMIVNGNPVTANVDPRTLLVQFLRENLRLTGTHVGCDTSQCGACVVHLDGKAVKSCTTLAVMADGHEVRTIEGLAA
DGAPLHPMQEAFREHHGLQCGFCTPGMIMTAVDLVHRKGHELSEETIREELEGNLCRCTGYQNIVQSIAAGAKAMAKSDL
A

Sequences:

>Translated_161_residues
MAKISMIVNGNPVTANVDPRTLLVQFLRENLRLTGTHVGCDTSQCGACVVHLDGKAVKSCTTLAVMADGHEVRTIEGLAA
DGAPLHPMQEAFREHHGLQCGFCTPGMIMTAVDLVHRKGHELSEETIREELEGNLCRCTGYQNIVQSIAAGAKAMAKSDL
A
>Mature_160_residues
AKISMIVNGNPVTANVDPRTLLVQFLRENLRLTGTHVGCDTSQCGACVVHLDGKAVKSCTTLAVMADGHEVRTIEGLAAD
GAPLHPMQEAFREHHGLQCGFCTPGMIMTAVDLVHRKGHELSEETIREELEGNLCRCTGYQNIVQSIAAGAKAMAKSDLA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=162, Percent_Identity=40.7407407407407, Blast_Score=94, Evalue=4e-20,
Organism=Homo sapiens, GI71773480, Length=157, Percent_Identity=36.3057324840764, Blast_Score=87, Evalue=8e-18,
Organism=Escherichia coli, GI1786480, Length=167, Percent_Identity=44.9101796407186, Blast_Score=130, Evalue=3e-32,
Organism=Escherichia coli, GI1789232, Length=146, Percent_Identity=44.5205479452055, Blast_Score=117, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17540638, Length=157, Percent_Identity=38.8535031847134, Blast_Score=105, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI32566215, Length=152, Percent_Identity=35.5263157894737, Blast_Score=96, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17539860, Length=152, Percent_Identity=36.8421052631579, Blast_Score=96, Evalue=7e-21,
Organism=Drosophila melanogaster, GI17737937, Length=162, Percent_Identity=40.7407407407407, Blast_Score=113, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24647197, Length=162, Percent_Identity=35.1851851851852, Blast_Score=100, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24647195, Length=162, Percent_Identity=35.1851851851852, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24647201, Length=155, Percent_Identity=35.4838709677419, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24647199, Length=152, Percent_Identity=35.5263157894737, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24647193, Length=140, Percent_Identity=37.1428571428571, Blast_Score=94, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 17225; Mature: 17094

Theoretical pI: Translated: 6.49; Mature: 6.49

Prosite motif: PS00028 ZINC_FINGER_C2H2_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
9.3 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
8.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKISMIVNGNPVTANVDPRTLLVQFLRENLRLTGTHVGCDTSQCGACVVHLDGKAVKSC
CCEEEEEECCCEEEECCCHHHHHHHHHHHCCEECCEECCCCCCCCCEEEEEECCHHHHHH
TTLAVMADGHEVRTIEGLAADGAPLHPMQEAFREHHGLQCGFCTPGMIMTAVDLVHRKGH
HEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHCCC
ELSEETIREELEGNLCRCTGYQNIVQSIAAGAKAMAKSDLA
CCHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AKISMIVNGNPVTANVDPRTLLVQFLRENLRLTGTHVGCDTSQCGACVVHLDGKAVKSC
CEEEEEECCCEEEECCCHHHHHHHHHHHCCEECCEECCCCCCCCCEEEEEECCHHHHHH
TTLAVMADGHEVRTIEGLAADGAPLHPMQEAFREHHGLQCGFCTPGMIMTAVDLVHRKGH
HEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHCCC
ELSEETIREELEGNLCRCTGYQNIVQSIAAGAKAMAKSDLA
CCHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 10430865; 12475995 [H]