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The map label for this gene is purQ [H]

Identifier: 146339779

GI number: 146339779

Start: 2987264

End: 2987965

Strand: Direct

Name: purQ [H]

Synonym: BRADO2779

Alternate gene names: 146339779

Gene position: 2987264-2987965 (Clockwise)

Preceding gene: 146339778

Following gene: 146339780

Centisome position: 40.06

GC content: 67.52

Gene sequence:

>702_bases
ATGAAATCCGCTGTCCTCGTCTTCCCCGGCATCAACCGCGAACGCGACATGGCCCGCGCGCTGCGCATGATCTCCGGCCA
TGAGCCCGCGATGGTCTGGCACGCCGAGACGTCGCTGCCAAAGGGCACCGACCTCGTCGTCGTCCCCGGCGGCTTCTCCT
ACGGCGACTACCTGCGCTGTGGCGCGATCGCGGCGCGGGCGCCGGTGATGGACGCGGTGCGCGATCACGCCGCGAAGGGC
GGACTGGTGCTCGGCGTCTGCAACGGCTTCCAGATCCTGTGCGAATCCGGCCTGCTGCCGGGCGTGCTGATGCGCAACGA
CCGGCTGAAGTTCATCTGCAAGGACGTGCATCTGCGCGTCGAGCGTTCGGATTCGCCGTTCACTCGCGGCTACAATGCGG
GCCAAGTCATCCGCGTGCCCGTCGCCCATGGCGAGGGCAACTACGCGGCCGACGAGGAGACGTTGAAGCGGCTCAATGGC
GACGGGCGCGTGCTCTATCGCTACTGCTCGGCCGAGGGCGAGGTCGGCGACCTCAGCAACATCAATGGCGCGGCGCATTC
GATCGCCGGGATCGTCAACGAGAACGGGAATGTGCTCGGCATGATGCCGCATCCCGAGAATCACGTCGAGGACATCATGG
GCTGCACCGACGGCCGCGGCCTGTTCGCCGGCCTCGTCGCCCATCTCGACCGCGCGGCCTGA

Upstream 100 bases:

>100_bases
TTCACCAGGAGCTCTCCAGGATTCACGCCACTTTGGTTCGCTCCGAGGGCCGTCTCGATCGCATCGAGCGGCGCCTCGAA
CTCAACGATGTGCCCACGCT

Downstream 100 bases:

>100_bases
TCGGCTCGCCGTGCTTCGTCACGTGTCATTCGGCCGCTCATAGGCCGGGCCTATCAAAGGGCGATTGGTGATCGAGGTTG
CGGGACGTTCCTCCATCTCC

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MKSAVLVFPGINRERDMARALRMISGHEPAMVWHAETSLPKGTDLVVVPGGFSYGDYLRCGAIAARAPVMDAVRDHAAKG
GLVLGVCNGFQILCESGLLPGVLMRNDRLKFICKDVHLRVERSDSPFTRGYNAGQVIRVPVAHGEGNYAADEETLKRLNG
DGRVLYRYCSAEGEVGDLSNINGAAHSIAGIVNENGNVLGMMPHPENHVEDIMGCTDGRGLFAGLVAHLDRAA

Sequences:

>Translated_233_residues
MKSAVLVFPGINRERDMARALRMISGHEPAMVWHAETSLPKGTDLVVVPGGFSYGDYLRCGAIAARAPVMDAVRDHAAKG
GLVLGVCNGFQILCESGLLPGVLMRNDRLKFICKDVHLRVERSDSPFTRGYNAGQVIRVPVAHGEGNYAADEETLKRLNG
DGRVLYRYCSAEGEVGDLSNINGAAHSIAGIVNENGNVLGMMPHPENHVEDIMGCTDGRGLFAGLVAHLDRAA
>Mature_233_residues
MKSAVLVFPGINRERDMARALRMISGHEPAMVWHAETSLPKGTDLVVVPGGFSYGDYLRCGAIAARAPVMDAVRDHAAKG
GLVLGVCNGFQILCESGLLPGVLMRNDRLKFICKDVHLRVERSDSPFTRGYNAGQVIRVPVAHGEGNYAADEETLKRLNG
DGRVLYRYCSAEGEVGDLSNINGAAHSIAGIVNENGNVLGMMPHPENHVEDIMGCTDGRGLFAGLVAHLDRAA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=225, Percent_Identity=34.2222222222222, Blast_Score=77, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321498, Length=181, Percent_Identity=34.8066298342541, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24582111, Length=238, Percent_Identity=29.8319327731092, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24582109, Length=238, Percent_Identity=29.8319327731092, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17137292, Length=238, Percent_Identity=29.8319327731092, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 24993; Mature: 24993

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSAVLVFPGINRERDMARALRMISGHEPAMVWHAETSLPKGTDLVVVPGGFSYGDYLRC
CCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCHHHH
GAIAARAPVMDAVRDHAAKGGLVLGVCNGFQILCESGLLPGVLMRNDRLKFICKDVHLRV
HHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCCCEEECCCCCEEEEEEEEEEE
ERSDSPFTRGYNAGQVIRVPVAHGEGNYAADEETLKRLNGDGRVLYRYCSAEGEVGDLSN
ECCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCC
INGAAHSIAGIVNENGNVLGMMPHPENHVEDIMGCTDGRGLFAGLVAHLDRAA
CCCHHHHHHHEEECCCCEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKSAVLVFPGINRERDMARALRMISGHEPAMVWHAETSLPKGTDLVVVPGGFSYGDYLRC
CCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCHHHH
GAIAARAPVMDAVRDHAAKGGLVLGVCNGFQILCESGLLPGVLMRNDRLKFICKDVHLRV
HHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCCCEEECCCCCEEEEEEEEEEE
ERSDSPFTRGYNAGQVIRVPVAHGEGNYAADEETLKRLNGDGRVLYRYCSAEGEVGDLSN
ECCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCC
INGAAHSIAGIVNENGNVLGMMPHPENHVEDIMGCTDGRGLFAGLVAHLDRAA
CCCHHHHHHHEEECCCCEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA