Click here to switch to the map view.

The map label for this gene is cat1 [H]

Identifier: 146339716

GI number: 146339716

Start: 2911419

End: 2912909

Strand: Reverse

Name: cat1 [H]

Synonym: BRADO2714

Alternate gene names: 146339716

Gene position: 2912909-2911419 (Counterclockwise)

Preceding gene: 146339717

Following gene: 146339713

Centisome position: 39.06

GC content: 66.47

Gene sequence:

>1491_bases
ATGAGTTCTTCGCAGGTGATGTCGCAGGCGCTGCGCGCCAAGATCATGTCGGCGGATGAGGCCGCCGCACTGGTCACGCC
GGGCAGCCATGTCGGCATGAGCGGCTTCACCGGCTCGGGCTATCCCAAGGCGGTGCCGATGGCGCTGGCGCGGCGCATCG
AGCAGGCGCATGCGCGCGGCGAGCCCTTCCGCATCGGCGTCTGGACCGGCGCCTCGACCGCGCCCGAACTCGACGGCGCG
CTCGCCAAGGCCAACGGCATCGACCTGCGCCTGCCCTATCAGTCCGATCCGACAACGCGCCAGCGCATCAACGCCGGCAG
CATCGAATATATCGACCTGCATCTCAGCCACGTCGCGCAATTCGTATGGTTCGGCTTCCTCGGCCATCTCGACGTCGCGG
TGATCGAATGCGCCGGCATCCTGCCGGACGGCCGGCTGATCCCGTCGACCTCGATCGGCAACAACAAGACCTGGCTCGAT
CAGGCCGATCGCGTGATCATCGAGGTCAATTCGTGGATGAACCCCGCGCTGCTCGGCATGCACGATGTCTACTACGGCAC
CCGGCTGCCGCCGCATCGCAAGCCGATCCCCATCATCGCGCCCGGCGACCGCATCGGCGAGACCACCTATCGCTGCAATC
CGAACAAGGTCATCGCCGTCGTCGAGACCCACGCGCCGGACCGCAACACTACCTTCGCGCCGCCAGACGATGTCTCGCGC
GCGATCGCGGGCCACATCCTGGAGTTCTTCGCGCACGAGGTGAAGCAGGGCCGGCTGCCGCGCAGCCTGCTGCCGCTGCA
ATCCGGTGTCGGCAATGTCGCCAATGCCGTGATGGCCGGGCTTGATGACGGGCCCTTCCCGCATCTGACCGCCTACACCG
AGGTGCTGCAGGACGGCATGCTCAACCTGCTCCGCTCGGGCCGGATGGATCTCGCGTCGGCGACCGCACTGTCGCTGAGC
TCGGAGGCCGCGATCGAGTTCAATCGCGAGATCGAGTTTCTGCGCGATCGCATCGTACTGCGGCCGCAGGAGATCTCCAA
CCATCCCGAGGTGATCCGCAGGCTCGGCGTGATCGCGATGAACGGCCTGATCGAGGCCGACATCTACGGCAACGTCAACT
CGACGCATGTCCGCGGCAGCAGCATCATGAACGGCATCGGCGGCTCCGGCGACTTTGCCCGCAACGCCTATCTGTCGATC
TTCATGACGCCGTCGACGGCGAAGGCCGGCACCATCTCCTGCATCGTGCCGATGGTGACGCATGTCGACCACACCGAGCA
CGACGTGCAGATCCTGGTCACCGAGCGCGGCCTCGCCGATCTGCGCGGCCTGTCGCCGAAGCAGCGCGCCCGCACGGTGA
TCGAGCAGGCAGCACATCCCAAATTCCGCCCTGCCCTGTCGGACTATTTCGAGCGCGCCTGCCGCGACTCCACCGGCAAG
CACACGCCGCATCTGCTGGAAGAGGCGTTCCGCCTGCTCAGGCCGGAGTGA

Upstream 100 bases:

>100_bases
GATAGCCCTGCGATTGACCCGTATCAAGACAGCACCGAAAGGCTCATCCTAAACAGCGCGCACTTGGGCGGACCCGACAG
TCCGCGTTGGAGCTGGCACG

Downstream 100 bases:

>100_bases
CTGACCAAGAGCATAGCCGAACCAGTCAAGCGTGAGGTCCGAGTTGAGCTTGCGCAGTCCATTCCGCGCCGTGATGCTCG
GCGAAGGCGGAGCATCCAGT

Product: putative acetyl-CoA hydrolase/transferase family protein succinyl-CoA:coenzyme A transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 495

Protein sequence:

>496_residues
MSSSQVMSQALRAKIMSADEAAALVTPGSHVGMSGFTGSGYPKAVPMALARRIEQAHARGEPFRIGVWTGASTAPELDGA
LAKANGIDLRLPYQSDPTTRQRINAGSIEYIDLHLSHVAQFVWFGFLGHLDVAVIECAGILPDGRLIPSTSIGNNKTWLD
QADRVIIEVNSWMNPALLGMHDVYYGTRLPPHRKPIPIIAPGDRIGETTYRCNPNKVIAVVETHAPDRNTTFAPPDDVSR
AIAGHILEFFAHEVKQGRLPRSLLPLQSGVGNVANAVMAGLDDGPFPHLTAYTEVLQDGMLNLLRSGRMDLASATALSLS
SEAAIEFNREIEFLRDRIVLRPQEISNHPEVIRRLGVIAMNGLIEADIYGNVNSTHVRGSSIMNGIGGSGDFARNAYLSI
FMTPSTAKAGTISCIVPMVTHVDHTEHDVQILVTERGLADLRGLSPKQRARTVIEQAAHPKFRPALSDYFERACRDSTGK
HTPHLLEEAFRLLRPE

Sequences:

>Translated_496_residues
MSSSQVMSQALRAKIMSADEAAALVTPGSHVGMSGFTGSGYPKAVPMALARRIEQAHARGEPFRIGVWTGASTAPELDGA
LAKANGIDLRLPYQSDPTTRQRINAGSIEYIDLHLSHVAQFVWFGFLGHLDVAVIECAGILPDGRLIPSTSIGNNKTWLD
QADRVIIEVNSWMNPALLGMHDVYYGTRLPPHRKPIPIIAPGDRIGETTYRCNPNKVIAVVETHAPDRNTTFAPPDDVSR
AIAGHILEFFAHEVKQGRLPRSLLPLQSGVGNVANAVMAGLDDGPFPHLTAYTEVLQDGMLNLLRSGRMDLASATALSLS
SEAAIEFNREIEFLRDRIVLRPQEISNHPEVIRRLGVIAMNGLIEADIYGNVNSTHVRGSSIMNGIGGSGDFARNAYLSI
FMTPSTAKAGTISCIVPMVTHVDHTEHDVQILVTERGLADLRGLSPKQRARTVIEQAAHPKFRPALSDYFERACRDSTGK
HTPHLLEEAFRLLRPE
>Mature_495_residues
SSSQVMSQALRAKIMSADEAAALVTPGSHVGMSGFTGSGYPKAVPMALARRIEQAHARGEPFRIGVWTGASTAPELDGAL
AKANGIDLRLPYQSDPTTRQRINAGSIEYIDLHLSHVAQFVWFGFLGHLDVAVIECAGILPDGRLIPSTSIGNNKTWLDQ
ADRVIIEVNSWMNPALLGMHDVYYGTRLPPHRKPIPIIAPGDRIGETTYRCNPNKVIAVVETHAPDRNTTFAPPDDVSRA
IAGHILEFFAHEVKQGRLPRSLLPLQSGVGNVANAVMAGLDDGPFPHLTAYTEVLQDGMLNLLRSGRMDLASATALSLSS
EAAIEFNREIEFLRDRIVLRPQEISNHPEVIRRLGVIAMNGLIEADIYGNVNSTHVRGSSIMNGIGGSGDFARNAYLSIF
MTPSTAKAGTISCIVPMVTHVDHTEHDVQILVTERGLADLRGLSPKQRARTVIEQAAHPKFRPALSDYFERACRDSTGKH
TPHLLEEAFRLLRPE

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=480, Percent_Identity=47.0833333333333, Blast_Score=454, Evalue=1e-129,
Organism=Caenorhabditis elegans, GI17538151, Length=483, Percent_Identity=24.223602484472, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI32563853, Length=225, Percent_Identity=29.7777777777778, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6319456, Length=511, Percent_Identity=44.4227005870841, Blast_Score=414, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 54035; Mature: 53904

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSQVMSQALRAKIMSADEAAALVTPGSHVGMSGFTGSGYPKAVPMALARRIEQAHARG
CCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
EPFRIGVWTGASTAPELDGALAKANGIDLRLPYQSDPTTRQRINAGSIEYIDLHLSHVAQ
CCEEEEEECCCCCCCCCCCHHHHCCCCEEECCCCCCCCHHHHCCCCCEEEEEHHHHHHHH
FVWFGFLGHLDVAVIECAGILPDGRLIPSTSIGNNKTWLDQADRVIIEVNSWMNPALLGM
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCCEEEEEECCCCCCHHHHH
HDVYYGTRLPPHRKPIPIIAPGDRIGETTYRCNPNKVIAVVETHAPDRNTTFAPPDDVSR
HHHHHCCCCCCCCCCCCEECCCCCCCCCCEEECCCEEEEEEEECCCCCCCCCCCCHHHHH
AIAGHILEFFAHEVKQGRLPRSLLPLQSGVGNVANAVMAGLDDGPFPHLTAYTEVLQDGM
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
LNLLRSGRMDLASATALSLSSEAAIEFNREIEFLRDRIVLRPQEISNHPEVIRRLGVIAM
HHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHEECCHHHCCCHHHHHHHHHHHH
NGLIEADIYGNVNSTHVRGSSIMNGIGGSGDFARNAYLSIFMTPSTAKAGTISCIVPMVT
CCEEEEEEECCCCCCEECCHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHH
HVDHTEHDVQILVTERGLADLRGLSPKQRARTVIEQAAHPKFRPALSDYFERACRDSTGK
HCCCCCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCC
HTPHLLEEAFRLLRPE
CCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSSQVMSQALRAKIMSADEAAALVTPGSHVGMSGFTGSGYPKAVPMALARRIEQAHARG
CHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
EPFRIGVWTGASTAPELDGALAKANGIDLRLPYQSDPTTRQRINAGSIEYIDLHLSHVAQ
CCEEEEEECCCCCCCCCCCHHHHCCCCEEECCCCCCCCHHHHCCCCCEEEEEHHHHHHHH
FVWFGFLGHLDVAVIECAGILPDGRLIPSTSIGNNKTWLDQADRVIIEVNSWMNPALLGM
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCCEEEEEECCCCCCHHHHH
HDVYYGTRLPPHRKPIPIIAPGDRIGETTYRCNPNKVIAVVETHAPDRNTTFAPPDDVSR
HHHHHCCCCCCCCCCCCEECCCCCCCCCCEEECCCEEEEEEEECCCCCCCCCCCCHHHHH
AIAGHILEFFAHEVKQGRLPRSLLPLQSGVGNVANAVMAGLDDGPFPHLTAYTEVLQDGM
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
LNLLRSGRMDLASATALSLSSEAAIEFNREIEFLRDRIVLRPQEISNHPEVIRRLGVIAM
HHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHEECCHHHCCCHHHHHHHHHHHH
NGLIEADIYGNVNSTHVRGSSIMNGIGGSGDFARNAYLSIFMTPSTAKAGTISCIVPMVT
CCEEEEEEECCCCCCEECCHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHH
HVDHTEHDVQILVTERGLADLRGLSPKQRARTVIEQAAHPKFRPALSDYFERACRDSTGK
HCCCCCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCC
HTPHLLEEAFRLLRPE
CCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]