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The map label for this gene is folB [H]

Identifier: 146339689

GI number: 146339689

Start: 2885182

End: 2885550

Strand: Reverse

Name: folB [H]

Synonym: BRADO2684

Alternate gene names: 146339689

Gene position: 2885550-2885182 (Counterclockwise)

Preceding gene: 146339690

Following gene: 146339688

Centisome position: 38.7

GC content: 65.31

Gene sequence:

>369_bases
ATGACCGATACGATCTTCATCAAGGGCGTCCTCATTCATGCCCGTCACGGCGTGATGGAGCATGAGAGCGAGGTCGGCCA
GCGCTTCGTGATCGATCTCGAGCTCTACACGGACCTGTCGGACTCCTCGCGCAGCGACCGGCTCGCCGACACCGTCTCCT
ATTCAGACGTGGTGGAGACGGCGACCGCCGCGTTCAAGGACACCAACTACCGCCTGCTCGAACGCGCCGCCGGCGCGGTC
GCCGATGCCATCCTGTCCACCTTCGTCCGCATCCGCGCCGTGAAGGTGACCGTGCACAAGCCGCATGCGCCGATCGCCGC
GATCTTCGAGGATGTCGGCGTCGTGCTGACGCGCTCGCGGCATCCGTGA

Upstream 100 bases:

>100_bases
ATCTGATCGCGGCGCAGCGCGGGGCTGCGATCATCCGGGCGCATGACGTCGCCGAGACGGTCCAGGCCGTGCGCGTGGCC
GCAAGCATCGAGGCACTGGG

Downstream 100 bases:

>100_bases
TCAGATGGCGAGCGCGCTGATCGCCCTCGGCGGCAATGTCGGCGACGTCAGGGCGACCTTCGTGCAGGCGATCGCGGAGA
TCTGCCGGCGCGCCGATGCC

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 122; Mature: 121

Protein sequence:

>122_residues
MTDTIFIKGVLIHARHGVMEHESEVGQRFVIDLELYTDLSDSSRSDRLADTVSYSDVVETATAAFKDTNYRLLERAAGAV
ADAILSTFVRIRAVKVTVHKPHAPIAAIFEDVGVVLTRSRHP

Sequences:

>Translated_122_residues
MTDTIFIKGVLIHARHGVMEHESEVGQRFVIDLELYTDLSDSSRSDRLADTVSYSDVVETATAAFKDTNYRLLERAAGAV
ADAILSTFVRIRAVKVTVHKPHAPIAAIFEDVGVVLTRSRHP
>Mature_121_residues
TDTIFIKGVLIHARHGVMEHESEVGQRFVIDLELYTDLSDSSRSDRLADTVSYSDVVETATAAFKDTNYRLLERAAGAVA
DAILSTFVRIRAVKVTVHKPHAPIAAIFEDVGVVLTRSRHP

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

Organism=Escherichia coli, GI87082204, Length=119, Percent_Identity=31.0924369747899, Blast_Score=63, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 13477; Mature: 13346

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTIFIKGVLIHARHGVMEHESEVGQRFVIDLELYTDLSDSSRSDRLADTVSYSDVVET
CCCEEEEEEEEEEHHCCCHHHHHHCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHH
ATAAFKDTNYRLLERAAGAVADAILSTFVRIRAVKVTVHKPHAPIAAIFEDVGVVLTRSR
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHEEECCC
HP
CC
>Mature Secondary Structure 
TDTIFIKGVLIHARHGVMEHESEVGQRFVIDLELYTDLSDSSRSDRLADTVSYSDVVET
CCEEEEEEEEEEHHCCCHHHHHHCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHH
ATAAFKDTNYRLLERAAGAVADAILSTFVRIRAVKVTVHKPHAPIAAIFEDVGVVLTRSR
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHEEECCC
HP
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]