BacMap

Definition	Bradyrhizobium sp. ORS278 chromosome, complete genome.
Accession	NC_009445
Length	7,456,587

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The map label for this gene is hpcC [H]

Identifier: 146339601

GI number: 146339601

Start: 2777538

End: 2779076

Strand: Reverse

Name: hpcC [H]

Synonym: BRADO2593

Alternate gene names: 146339601

Gene position: 2779076-2777538 (Counterclockwise)

Preceding gene: 146339602

Following gene: 146339600

Centisome position: 37.27

GC content: 66.86

Gene sequence:

>1539_bases
ATGGATAAGGCCACTCCCAAAGCCGACATCTACCAGGCCAACCTCGACCGCGCCGCCCCCCTGCTCGCGAAGCTTAAGGA
CGAAGGCATCGGTCATTTCATTGACGGCGAGGTTGTGCCGGCCATCTCGGGCGCGACGTTCGAAACAAGGTCGCCGATCG
ACAATGCCGTGCTGGCCACCGTCGCGCGTGGCAATGCCGAGGACATCGATCGCGCTGCGACCTCCGCGGCGCTGGCCTTC
AGGTCCTGGCGGGAGATGGCCCCGGCGATGCGCCGCAAGCTGCTGCACCGCATGGCCGATGCGATCGAGGATCATGCCGA
CGACATCGCGGTGCTCGAATGCATCGACACCGGCCAGGCCTATCGCTTCATGGCCAAGGCGGCGATCCGCGCGGCGGAGA
ACTTTCGCTTCTTCGCCGACAAATGCACCGAGGCGCGCGACGGCCTGAGCACGCCGAGCGAGGAGCATTGGAACATCTCC
ACCCGCGTGCCGATCGGTCCGGTCGGCGTGATCACGCCGTGGAACACGCCATTCATGCTGTCGACCTGGAAGATCGCGCC
CGCCCTCGCCGCGGGCTGCACGGTCGTGCACAAACCGGCCGAGTGGTCCCCGATCACGGCGCAATGGCTGGCGAAGCTCG
CCAAGGACGCCGGCATTCCCGACGGCGTGCTCAACACGGTGCATGGCTTCGGCGAGGAAGCCGGCAAGGCGCTGACCGAG
CATCCCGCGATCAAGGCAATCGGCTTCGTCGGCGAAAGCTCGACGGGCTCGGCCATCATGGCGCAGGGCGCGCCCACCCT
GAAGCGGGTGCATTTCGAGCTCGGCGGCAAGAACCCGGTGATCGTGTTCGATGACGCCGATCTCGACCGCGCGCTCGATG
CGGTCGTGTTCATGATCTACTCGCTCAATGGTGAGCGCTGCACGTCGTCGAGCAGGCTATTGGTGCAGCAGAGCATCGCG
GAAACCTTCACGGCCAAGCTTGCCGCCCGCGTGCGCGCGCTGAAGGTCGGCCATCCGCTCGATCCGGCGACGGAGATCGG
GCCGCTGATCCATGAGCGGCATCTCGCCAAGGTCTGCTCCTATGCCGACGTCGCGCGGCAGGACGGCGCGATCATTGCCG
TCGGCGGCAAGCCGTTCGCCGGCCCCGGCGGCGGCCATTATGTCGAGCCGACCTTGGTGACCGGCGCAAGCCAGACCATG
CGCGTCGCGCAGGAGGAGGTGTTCGGGCCGTTCCTCACCGTGATTCCGTTCCGCGACGAGGCCGACGCGGTCGCGATCGC
CAACGACGTGCAATATGGCCTCACCGGCTACGTCTGGACCGGCGACATGGGCCGCGCGCTGCGCGTCGCTGACGCGCTGG
AGGCCGGCATGATCTGGCTGAACTCGGAGAACGTCCGCCATCTGCCGACGCCGTTCGGCGGCATGAAGGCGTCCGGCATC
GGCCGCGACGGCGGCGACTATTCGTTCGACTTCTACATGGAGACCAAGCACGTCTCGCTCGCGCGCGGCACCCACAAGAT
CCAGCGGCTCGGCGTATAA

Upstream 100 bases:

>100_bases
GGCAGCAAATTCGCGCTGTCCTTCGACATGCAGATCAACGACGCCGCGACCAGTTGGAAGCGCAACAACATCCACGACGC
CCTGAAAGCGGAGGCATCCC

Downstream 100 bases:

>100_bases
GGAGACCAGCCCATGACCTCCCCGCGCCTCGCGACCTACGCGATCAACGGCTCCGTCCGCTACGGCCTCGTCAACGACAA
CGGCCTCGTCGATCTCTCCG

Product: putative 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase

Products: 5-carboxymethyl-2-hydroxymuconate; NADH; H+

Alternate protein names: CHMS dehydrogenase [H]

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MDKATPKADIYQANLDRAAPLLAKLKDEGIGHFIDGEVVPAISGATFETRSPIDNAVLATVARGNAEDIDRAATSAALAF
RSWREMAPAMRRKLLHRMADAIEDHADDIAVLECIDTGQAYRFMAKAAIRAAENFRFFADKCTEARDGLSTPSEEHWNIS
TRVPIGPVGVITPWNTPFMLSTWKIAPALAAGCTVVHKPAEWSPITAQWLAKLAKDAGIPDGVLNTVHGFGEEAGKALTE
HPAIKAIGFVGESSTGSAIMAQGAPTLKRVHFELGGKNPVIVFDDADLDRALDAVVFMIYSLNGERCTSSSRLLVQQSIA
ETFTAKLAARVRALKVGHPLDPATEIGPLIHERHLAKVCSYADVARQDGAIIAVGGKPFAGPGGGHYVEPTLVTGASQTM
RVAQEEVFGPFLTVIPFRDEADAVAIANDVQYGLTGYVWTGDMGRALRVADALEAGMIWLNSENVRHLPTPFGGMKASGI
GRDGGDYSFDFYMETKHVSLARGTHKIQRLGV

Sequences:

>Translated_512_residues
MDKATPKADIYQANLDRAAPLLAKLKDEGIGHFIDGEVVPAISGATFETRSPIDNAVLATVARGNAEDIDRAATSAALAF
RSWREMAPAMRRKLLHRMADAIEDHADDIAVLECIDTGQAYRFMAKAAIRAAENFRFFADKCTEARDGLSTPSEEHWNIS
TRVPIGPVGVITPWNTPFMLSTWKIAPALAAGCTVVHKPAEWSPITAQWLAKLAKDAGIPDGVLNTVHGFGEEAGKALTE
HPAIKAIGFVGESSTGSAIMAQGAPTLKRVHFELGGKNPVIVFDDADLDRALDAVVFMIYSLNGERCTSSSRLLVQQSIA
ETFTAKLAARVRALKVGHPLDPATEIGPLIHERHLAKVCSYADVARQDGAIIAVGGKPFAGPGGGHYVEPTLVTGASQTM
RVAQEEVFGPFLTVIPFRDEADAVAIANDVQYGLTGYVWTGDMGRALRVADALEAGMIWLNSENVRHLPTPFGGMKASGI
GRDGGDYSFDFYMETKHVSLARGTHKIQRLGV
>Mature_512_residues
MDKATPKADIYQANLDRAAPLLAKLKDEGIGHFIDGEVVPAISGATFETRSPIDNAVLATVARGNAEDIDRAATSAALAF
RSWREMAPAMRRKLLHRMADAIEDHADDIAVLECIDTGQAYRFMAKAAIRAAENFRFFADKCTEARDGLSTPSEEHWNIS
TRVPIGPVGVITPWNTPFMLSTWKIAPALAAGCTVVHKPAEWSPITAQWLAKLAKDAGIPDGVLNTVHGFGEEAGKALTE
HPAIKAIGFVGESSTGSAIMAQGAPTLKRVHFELGGKNPVIVFDDADLDRALDAVVFMIYSLNGERCTSSSRLLVQQSIA
ETFTAKLAARVRALKVGHPLDPATEIGPLIHERHLAKVCSYADVARQDGAIIAVGGKPFAGPGGGHYVEPTLVTGASQTM
RVAQEEVFGPFLTVIPFRDEADAVAIANDVQYGLTGYVWTGDMGRALRVADALEAGMIWLNSENVRHLPTPFGGMKASGI
GRDGGDYSFDFYMETKHVSLARGTHKIQRLGV

Specific function: Transforms 5-carboxymethyl-2-hydroxy-muconic semialdehyde (CHMS) into 5-carboxymethyl-2-hydroxy-muconic acid (CHM) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI12007648, Length=484, Percent_Identity=38.8429752066116, Blast_Score=341, Evalue=9e-94,
Organism=Homo sapiens, GI153266822, Length=513, Percent_Identity=36.0623781676413, Blast_Score=327, Evalue=2e-89,
Organism=Homo sapiens, GI238814322, Length=479, Percent_Identity=36.1169102296451, Blast_Score=322, Evalue=4e-88,
Organism=Homo sapiens, GI25777732, Length=477, Percent_Identity=37.1069182389937, Blast_Score=318, Evalue=5e-87,
Organism=Homo sapiens, GI21361176, Length=489, Percent_Identity=36.6053169734151, Blast_Score=315, Evalue=4e-86,
Organism=Homo sapiens, GI21614513, Length=479, Percent_Identity=37.160751565762, Blast_Score=315, Evalue=5e-86,
Organism=Homo sapiens, GI25777730, Length=477, Percent_Identity=36.4779874213836, Blast_Score=313, Evalue=2e-85,
Organism=Homo sapiens, GI25777724, Length=477, Percent_Identity=36.0587002096436, Blast_Score=311, Evalue=7e-85,
Organism=Homo sapiens, GI115387104, Length=518, Percent_Identity=32.2393822393822, Blast_Score=291, Evalue=1e-78,
Organism=Homo sapiens, GI25777728, Length=421, Percent_Identity=36.5795724465558, Blast_Score=287, Evalue=2e-77,
Organism=Homo sapiens, GI25952152, Length=484, Percent_Identity=34.297520661157, Blast_Score=275, Evalue=1e-73,
Organism=Homo sapiens, GI4507229, Length=475, Percent_Identity=36.6315789473684, Blast_Score=271, Evalue=8e-73,
Organism=Homo sapiens, GI25777726, Length=476, Percent_Identity=33.1932773109244, Blast_Score=267, Evalue=2e-71,
Organism=Homo sapiens, GI25777721, Length=488, Percent_Identity=35.4508196721311, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI301500698, Length=281, Percent_Identity=40.5693950177936, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI11095441, Length=477, Percent_Identity=29.3501048218029, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI188035924, Length=495, Percent_Identity=27.0707070707071, Blast_Score=187, Evalue=3e-47,
Organism=Homo sapiens, GI310128103, Length=477, Percent_Identity=27.2536687631027, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI310128093, Length=476, Percent_Identity=26.890756302521, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI310128091, Length=462, Percent_Identity=26.6233766233766, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI223972651, Length=476, Percent_Identity=28.5714285714286, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI310128089, Length=293, Percent_Identity=30.0341296928328, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI73466520, Length=332, Percent_Identity=29.2168674698795, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI4557303, Length=332, Percent_Identity=29.2168674698795, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI310128097, Length=258, Percent_Identity=30.6201550387597, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI223972653, Length=476, Percent_Identity=25.6302521008403, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI310128095, Length=292, Percent_Identity=28.0821917808219, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI73695881, Length=350, Percent_Identity=27.1428571428571, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI73695879, Length=350, Percent_Identity=27.1428571428571, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI71773324, Length=332, Percent_Identity=28.0120481927711, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI4502043, Length=332, Percent_Identity=28.0120481927711, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI238814371, Length=332, Percent_Identity=28.0120481927711, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI206597441, Length=332, Percent_Identity=28.6144578313253, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI206597439, Length=332, Percent_Identity=28.6144578313253, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI22907049, Length=332, Percent_Identity=28.6144578313253, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI238859541, Length=457, Percent_Identity=26.4770240700219, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI25777736, Length=457, Percent_Identity=26.4770240700219, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI25777734, Length=457, Percent_Identity=26.4770240700219, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI310128087, Length=471, Percent_Identity=22.7176220806794, Blast_Score=101, Evalue=2e-21,
Organism=Escherichia coli, GI1787558, Length=471, Percent_Identity=40.1273885350318, Blast_Score=335, Evalue=4e-93,
Organism=Escherichia coli, GI87081896, Length=489, Percent_Identity=37.6278118609407, Blast_Score=326, Evalue=3e-90,
Organism=Escherichia coli, GI1786504, Length=472, Percent_Identity=38.135593220339, Blast_Score=309, Evalue=3e-85,
Organism=Escherichia coli, GI1787715, Length=469, Percent_Identity=39.8720682302772, Blast_Score=307, Evalue=1e-84,
Organism=Escherichia coli, GI1789015, Length=470, Percent_Identity=36.3829787234043, Blast_Score=303, Evalue=2e-83,
Organism=Escherichia coli, GI87082295, Length=477, Percent_Identity=35.2201257861635, Blast_Score=281, Evalue=6e-77,
Organism=Escherichia coli, GI1787684, Length=470, Percent_Identity=32.5531914893617, Blast_Score=244, Evalue=7e-66,
Organism=Escherichia coli, GI87081926, Length=448, Percent_Identity=28.125, Blast_Score=178, Evalue=9e-46,
Organism=Escherichia coli, GI1788042, Length=471, Percent_Identity=29.9363057324841, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI1787250, Length=466, Percent_Identity=27.8969957081545, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1787653, Length=282, Percent_Identity=25.177304964539, Blast_Score=79, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI25144435, Length=506, Percent_Identity=36.3636363636364, Blast_Score=327, Evalue=7e-90,
Organism=Caenorhabditis elegans, GI133930964, Length=480, Percent_Identity=37.5, Blast_Score=327, Evalue=7e-90,
Organism=Caenorhabditis elegans, GI17562198, Length=473, Percent_Identity=36.3636363636364, Blast_Score=311, Evalue=6e-85,
Organism=Caenorhabditis elegans, GI71995606, Length=476, Percent_Identity=35.5042016806723, Blast_Score=291, Evalue=4e-79,
Organism=Caenorhabditis elegans, GI25143876, Length=476, Percent_Identity=34.2436974789916, Blast_Score=288, Evalue=6e-78,
Organism=Caenorhabditis elegans, GI25143874, Length=476, Percent_Identity=34.2436974789916, Blast_Score=287, Evalue=8e-78,
Organism=Caenorhabditis elegans, GI32564736, Length=418, Percent_Identity=35.8851674641148, Blast_Score=274, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI17551164, Length=493, Percent_Identity=34.4827586206897, Blast_Score=273, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17534119, Length=477, Percent_Identity=34.8008385744235, Blast_Score=256, Evalue=3e-68,
Organism=Caenorhabditis elegans, GI71995613, Length=419, Percent_Identity=35.5608591885441, Blast_Score=254, Evalue=1e-67,
Organism=Caenorhabditis elegans, GI71986308, Length=480, Percent_Identity=29.5833333333333, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI115534176, Length=499, Percent_Identity=28.6573146292585, Blast_Score=191, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI17534447, Length=460, Percent_Identity=27.3913043478261, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI32566756, Length=343, Percent_Identity=28.5714285714286, Blast_Score=125, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI25146394, Length=343, Percent_Identity=28.5714285714286, Blast_Score=125, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI25146391, Length=343, Percent_Identity=28.5714285714286, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI115532534, Length=335, Percent_Identity=28.955223880597, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17564084, Length=337, Percent_Identity=28.486646884273, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI32564151, Length=421, Percent_Identity=27.3159144893112, Blast_Score=113, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6320917, Length=510, Percent_Identity=36.2745098039216, Blast_Score=337, Evalue=3e-93,
Organism=Saccharomyces cerevisiae, GI6324950, Length=474, Percent_Identity=37.3417721518987, Blast_Score=332, Evalue=9e-92,
Organism=Saccharomyces cerevisiae, GI6323822, Length=497, Percent_Identity=34.8088531187123, Blast_Score=301, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6323821, Length=497, Percent_Identity=33.8028169014084, Blast_Score=288, Evalue=2e-78,
Organism=Saccharomyces cerevisiae, GI6325196, Length=478, Percent_Identity=33.6820083682008, Blast_Score=286, Evalue=5e-78,
Organism=Saccharomyces cerevisiae, GI6319478, Length=479, Percent_Identity=33.6116910229645, Blast_Score=272, Evalue=1e-73,
Organism=Saccharomyces cerevisiae, GI6321828, Length=464, Percent_Identity=25.6465517241379, Blast_Score=144, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6321826, Length=517, Percent_Identity=24.1779497098646, Blast_Score=110, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6323757, Length=329, Percent_Identity=27.355623100304, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24650465, Length=475, Percent_Identity=38.5263157894737, Blast_Score=331, Evalue=6e-91,
Organism=Drosophila melanogaster, GI20129399, Length=475, Percent_Identity=37.2631578947368, Blast_Score=315, Evalue=3e-86,
Organism=Drosophila melanogaster, GI24585660, Length=478, Percent_Identity=35.5648535564854, Blast_Score=307, Evalue=1e-83,
Organism=Drosophila melanogaster, GI281362580, Length=464, Percent_Identity=37.0689655172414, Blast_Score=297, Evalue=1e-80,
Organism=Drosophila melanogaster, GI62472918, Length=464, Percent_Identity=37.0689655172414, Blast_Score=297, Evalue=1e-80,
Organism=Drosophila melanogaster, GI62472926, Length=464, Percent_Identity=37.0689655172414, Blast_Score=297, Evalue=1e-80,
Organism=Drosophila melanogaster, GI62472936, Length=464, Percent_Identity=37.0689655172414, Blast_Score=297, Evalue=1e-80,
Organism=Drosophila melanogaster, GI21356737, Length=464, Percent_Identity=37.0689655172414, Blast_Score=297, Evalue=1e-80,
Organism=Drosophila melanogaster, GI24666674, Length=468, Percent_Identity=25, Blast_Score=176, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24638878, Length=480, Percent_Identity=25.625, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24638876, Length=480, Percent_Identity=25.625, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI281360301, Length=445, Percent_Identity=24.2696629213483, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI281360299, Length=449, Percent_Identity=24.7216035634744, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI281360297, Length=449, Percent_Identity=24.7216035634744, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI281360295, Length=449, Percent_Identity=24.7216035634744, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24586250, Length=449, Percent_Identity=24.7216035634744, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI281360303, Length=449, Percent_Identity=24.9443207126949, Blast_Score=112, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24668425, Length=449, Percent_Identity=22.9398663697105, Blast_Score=111, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24668417, Length=449, Percent_Identity=22.9398663697105, Blast_Score=111, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24668413, Length=449, Percent_Identity=22.9398663697105, Blast_Score=111, Evalue=9e-25,
Organism=Drosophila melanogaster, GI45552499, Length=449, Percent_Identity=24.9443207126949, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28574525, Length=461, Percent_Identity=23.8611713665944, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI28571802, Length=313, Percent_Identity=25.2396166134185, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28571800, Length=313, Percent_Identity=25.2396166134185, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28571806, Length=313, Percent_Identity=25.2396166134185, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28571798, Length=313, Percent_Identity=25.2396166134185, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28571796, Length=313, Percent_Identity=25.2396166134185, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28571794, Length=313, Percent_Identity=25.2396166134185, Blast_Score=86, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR011985 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: 1.2.1.60

Molecular weight: Translated: 54950; Mature: 54950

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKATPKADIYQANLDRAAPLLAKLKDEGIGHFIDGEVVPAISGATFETRSPIDNAVLAT
CCCCCCCCHHEECCHHHHHHHHHHHHHCCCCEEECCCEEECCCCCCCCCCCCCCHHHHHH
VARGNAEDIDRAATSAALAFRSWREMAPAMRRKLLHRMADAIEDHADDIAVLECIDTGQA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHH
YRFMAKAAIRAAENFRFFADKCTEARDGLSTPSEEHWNISTRVPIGPVGVITPWNTPFML
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCEEEECCCCCCEEE
STWKIAPALAAGCTVVHKPAEWSPITAQWLAKLAKDAGIPDGVLNTVHGFGEEAGKALTE
EEHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHC
HPAIKAIGFVGESSTGSAIMAQGAPTLKRVHFELGGKNPVIVFDDADLDRALDAVVFMIY
CCCEEEEEECCCCCCCCEEEECCCCHHEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHH
SLNGERCTSSSRLLVQQSIAETFTAKLAARVRALKVGHPLDPATEIGPLIHERHLAKVCS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
YADVARQDGAIIAVGGKPFAGPGGGHYVEPTLVTGASQTMRVAQEEVFGPFLTVIPFRDE
HHHHHHCCCCEEEECCCCCCCCCCCCEECCEEECCCHHHHHHHHHHHCCCEEEEEECCCC
ADAVAIANDVQYGLTGYVWTGDMGRALRVADALEAGMIWLNSENVRHLPTPFGGMKASGI
CCEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHCEEEECCCCCCCCCCCCCCCCCCCC
GRDGGDYSFDFYMETKHVSLARGTHKIQRLGV
CCCCCCCEEEEEEEECEEEHHHHHHHHHHCCC
>Mature Secondary Structure
MDKATPKADIYQANLDRAAPLLAKLKDEGIGHFIDGEVVPAISGATFETRSPIDNAVLAT
CCCCCCCCHHEECCHHHHHHHHHHHHHCCCCEEECCCEEECCCCCCCCCCCCCCHHHHHH
VARGNAEDIDRAATSAALAFRSWREMAPAMRRKLLHRMADAIEDHADDIAVLECIDTGQA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHH
YRFMAKAAIRAAENFRFFADKCTEARDGLSTPSEEHWNISTRVPIGPVGVITPWNTPFML
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCEEEECCCCCCEEE
STWKIAPALAAGCTVVHKPAEWSPITAQWLAKLAKDAGIPDGVLNTVHGFGEEAGKALTE
EEHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHC
HPAIKAIGFVGESSTGSAIMAQGAPTLKRVHFELGGKNPVIVFDDADLDRALDAVVFMIY
CCCEEEEEECCCCCCCCEEEECCCCHHEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHH
SLNGERCTSSSRLLVQQSIAETFTAKLAARVRALKVGHPLDPATEIGPLIHERHLAKVCS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
YADVARQDGAIIAVGGKPFAGPGGGHYVEPTLVTGASQTMRVAQEEVFGPFLTVIPFRDE
HHHHHHCCCCEEEECCCCCCCCCCCCEECCEEECCCHHHHHHHHHHHCCCEEEEEECCCC
ADAVAIANDVQYGLTGYVWTGDMGRALRVADALEAGMIWLNSENVRHLPTPFGGMKASGI
CCEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHCEEEECCCCCCCCCCCCCCCCCCCC
GRDGGDYSFDFYMETKHVSLARGTHKIQRLGV
CCCCCCCEEEEEEEECEEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5-carboxymethyl-2-hydroxymuconate semialdehyde; H2O; NAD+

Specific reaction: 5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7737515 [H]