Click here to switch to the map view.

The map label for this gene is bioI [H]

Identifier: 146339509

GI number: 146339509

Start: 2668481

End: 2669710

Strand: Reverse

Name: bioI [H]

Synonym: BRADO2499

Alternate gene names: 146339509

Gene position: 2669710-2668481 (Counterclockwise)

Preceding gene: 146339513

Following gene: 146339508

Centisome position: 35.8

GC content: 66.83

Gene sequence:

>1230_bases
ATGACCGATGCCGCAGCGCTCGCCGACGATTTCGATCTCGAGCGCCTGACGCCCGGCTTCTACGCCGACCCCTACCGAAC
CTATCGCGCGCTGCGCCAGTATGCGCCGGTCAAGCGGATGCGCAACGGCTCGTATTTCCTGACGCGCTACGACGATCTCG
TCACCGCCTACAAGACGACGAAGGCCTTTTCGTCCGACAAGAAGCGCGAGTTCGCGCCGAAATACGGCGATTCATTGCTG
TATGAGCATCACACCACGAGCCTCGTGTTCAACGATCCGCCGTCGCATACGCGCGTCCGCCGCCTGATCATGGGCGCGCT
GTCGCCGCGCGCCATCGCCGAGATGGAGCCGGCGCTGATCGCACTGGTGGACGGCCTGCTGGATCGCATCGCGGCGAAGC
CGCGCTTCGAGCTGATCGAGGATTTCGCCGCGGCGATTCCGATCGAGGTGATCGGCAATCTGCTCGGGGTGCCGCATGAG
GAGCGCGGCCCGCTGCGCGACTGGTCGCTCGCCATTCTCGGCGCGCTCGAGCCGGTGCTGACGCCGGAGCAGTTGGCGCG
CGGCAACCAGGCCGTTGCAGATTTCCTGGACTATCTCAAAACTCTGGTCGCGCGCCGCCGCGCCAGGCCCGGCCATCCCG
AGCGCGACGTGCTGACGCGGCTGATCCAGGGCGAATCCGATGACGAAAACGGCGGCGAGCGGCTCAGCGAGAAGGAGCTG
CTGCACAATTGCATCTTCCTGCTCAACGCCGGCCACGAGACCACCACCAACCTGATCGGCAACGGCCTCGTGCTGCTGTG
CCAGCATCCGGCCGAGCGCAAGAAGCTGATCGAGGCCCCCGCCTTGATCCGCACCGCCGTCGAGGAGATCCTGCGCTACG
AAAGCTCCAACCAGCTCGGCAACCGCATGACCACGGAAGCCGTCGAGCTCGGCGGCATCACGCTGGCGCCCGGCACCTCC
GTCACCCTGTGCATCGGCGCCGCCAACCGCGACCCCGCCCAGTTCGATGACCCCGAACGCTTCGACATCACCCGGATTGC
CAACCGCCACCTCGCCTTCGGAACGGGCGCGCATCAATGCGCGGGCATGGCGCTGGCGCGGCTGGAAGGCGCAGTGGCGA
TCGCGCGGTTTGTGAGCCGGTTTCCCAACTATCAGCTCGCGGGCGAGCCGGTGCGCGGCGGACGGGTGCGGTTTCGGGGG
TTCGCGAGCGTGCCATGCGTGGTTAGCTAA

Upstream 100 bases:

>100_bases
GTGGCAGGTGGGCAGCTGGACACCACCCGGCGCATTTTCTTCCGCCGCTGGCCGTGCGACGGTCGCGACAACAACGAAGA
CTCGACCGGGAGGACCAGAG

Downstream 100 bases:

>100_bases
GGAGAGGATCACGTCGCGCGTCACGACTTGAGCAATTCAGTCAGCCAATCGTAGGGCGCATTAGGGGCGTCTCGAAGGGC
GAGGCCCGGCTGGTGGCCTC

Product: putative cytochrome P450

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MTDAAALADDFDLERLTPGFYADPYRTYRALRQYAPVKRMRNGSYFLTRYDDLVTAYKTTKAFSSDKKREFAPKYGDSLL
YEHHTTSLVFNDPPSHTRVRRLIMGALSPRAIAEMEPALIALVDGLLDRIAAKPRFELIEDFAAAIPIEVIGNLLGVPHE
ERGPLRDWSLAILGALEPVLTPEQLARGNQAVADFLDYLKTLVARRRARPGHPERDVLTRLIQGESDDENGGERLSEKEL
LHNCIFLLNAGHETTTNLIGNGLVLLCQHPAERKKLIEAPALIRTAVEEILRYESSNQLGNRMTTEAVELGGITLAPGTS
VTLCIGAANRDPAQFDDPERFDITRIANRHLAFGTGAHQCAGMALARLEGAVAIARFVSRFPNYQLAGEPVRGGRVRFRG
FASVPCVVS

Sequences:

>Translated_409_residues
MTDAAALADDFDLERLTPGFYADPYRTYRALRQYAPVKRMRNGSYFLTRYDDLVTAYKTTKAFSSDKKREFAPKYGDSLL
YEHHTTSLVFNDPPSHTRVRRLIMGALSPRAIAEMEPALIALVDGLLDRIAAKPRFELIEDFAAAIPIEVIGNLLGVPHE
ERGPLRDWSLAILGALEPVLTPEQLARGNQAVADFLDYLKTLVARRRARPGHPERDVLTRLIQGESDDENGGERLSEKEL
LHNCIFLLNAGHETTTNLIGNGLVLLCQHPAERKKLIEAPALIRTAVEEILRYESSNQLGNRMTTEAVELGGITLAPGTS
VTLCIGAANRDPAQFDDPERFDITRIANRHLAFGTGAHQCAGMALARLEGAVAIARFVSRFPNYQLAGEPVRGGRVRFRG
FASVPCVVS
>Mature_408_residues
TDAAALADDFDLERLTPGFYADPYRTYRALRQYAPVKRMRNGSYFLTRYDDLVTAYKTTKAFSSDKKREFAPKYGDSLLY
EHHTTSLVFNDPPSHTRVRRLIMGALSPRAIAEMEPALIALVDGLLDRIAAKPRFELIEDFAAAIPIEVIGNLLGVPHEE
RGPLRDWSLAILGALEPVLTPEQLARGNQAVADFLDYLKTLVARRRARPGHPERDVLTRLIQGESDDENGGERLSEKELL
HNCIFLLNAGHETTTNLIGNGLVLLCQHPAERKKLIEAPALIRTAVEEILRYESSNQLGNRMTTEAVELGGITLAPGTSV
TLCIGAANRDPAQFDDPERFDITRIANRHLAFGTGAHQCAGMALARLEGAVAIARFVSRFPNYQLAGEPVRGGRVRFRGF
ASVPCVVS

Specific function: Catalyzes the C-C bond cleavage of fatty acid linked to acyl carrier protein (ACP) to generate pimelic acid for biotin biosynthesis. It has high affinity for long-chain fatty acids with the greatest affinity for myristic acid [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

Organism=Homo sapiens, GI4503213, Length=195, Percent_Identity=28.2051282051282, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115532670, Length=218, Percent_Identity=25.6880733944954, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24642101, Length=170, Percent_Identity=28.2352941176471, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 45245; Mature: 45114

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAAALADDFDLERLTPGFYADPYRTYRALRQYAPVKRMRNGSYFLTRYDDLVTAYKTT
CCCHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHH
KAFSSDKKREFAPKYGDSLLYEHHTTSLVFNDPPSHTRVRRLIMGALSPRAIAEMEPALI
HHHCCCHHHHCCCCCCCCCEEECCCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHCHHHH
ALVDGLLDRIAAKPRFELIEDFAAAIPIEVIGNLLGVPHEERGPLRDWSLAILGALEPVL
HHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCC
TPEQLARGNQAVADFLDYLKTLVARRRARPGHPERDVLTRLIQGESDDENGGERLSEKEL
CHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHH
LHNCIFLLNAGHETTTNLIGNGLVLLCQHPAERKKLIEAPALIRTAVEEILRYESSNQLG
HHHHHHHHCCCCHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHC
NRMTTEAVELGGITLAPGTSVTLCIGAANRDPAQFDDPERFDITRIANRHLAFGTGAHQC
CHHHHHHHHHCCEEECCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHH
AGMALARLEGAVAIARFVSRFPNYQLAGEPVRGGRVRFRGFASVPCVVS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure 
TDAAALADDFDLERLTPGFYADPYRTYRALRQYAPVKRMRNGSYFLTRYDDLVTAYKTT
CCHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHH
KAFSSDKKREFAPKYGDSLLYEHHTTSLVFNDPPSHTRVRRLIMGALSPRAIAEMEPALI
HHHCCCHHHHCCCCCCCCCEEECCCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHCHHHH
ALVDGLLDRIAAKPRFELIEDFAAAIPIEVIGNLLGVPHEERGPLRDWSLAILGALEPVL
HHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCC
TPEQLARGNQAVADFLDYLKTLVARRRARPGHPERDVLTRLIQGESDDENGGERLSEKEL
CHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHH
LHNCIFLLNAGHETTTNLIGNGLVLLCQHPAERKKLIEAPALIRTAVEEILRYESSNQLG
HHHHHHHHCCCCHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHC
NRMTTEAVELGGITLAPGTSVTLCIGAANRDPAQFDDPERFDITRIANRHLAFGTGAHQC
CHHHHHHHHHCCEEECCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHH
AGMALARLEGAVAIARFVSRFPNYQLAGEPVRGGRVRFRGFASVPCVVS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8763940; 9387221; 9384377 [H]