Click here to switch to the map view.

The map label for this gene is ade1

Identifier: 146339472

GI number: 146339472

Start: 2621225

End: 2623099

Strand: Reverse

Name: ade1

Synonym: BRADO2460

Alternate gene names: 146339472

Gene position: 2623099-2621225 (Counterclockwise)

Preceding gene: 146339473

Following gene: 146339471

Centisome position: 35.18

GC content: 69.07

Gene sequence:

>1875_bases
ATGGATCTCGCGCAGGACATTGCAGACGACCTCATGATCGACGCCGCGCAGGAGGTCCGGATCCGCCAGGACCTGGTGCT
GACCGCGCTCGGCCACCGCCCCGCCGATCGCGCGCTCCGCGTCGGCCGCCTGCTCGACGTCCACAGCCGGACCTGGAGCG
AGGACCAGGAGATCGTCTTCAAGGGACGGCGCATCGCCTGGGTCGGCCCCGCCGGCAGCTATCGCGGCGAAGTGCGCGAA
CGCGTGCAGCGGCCCGATCTCGCCGCCGTTCCCGGCTTCGGCGAGGTGCACAAGCACATCGAGAGCTCGCACCTGACGCC
GGAGTGGGAGGCGGCGCTGGTGCTGCCGCGCGGCAATACCTGGACCTGCGAGGCAAGCCACGAATTCTCCAACGTCAACG
GCGCGCGCAATCTCGAATTCTGGTTCGAGGCGCGGCGTCGCGGCTCGCCGCTGAAGATCTTTCCGCAGCCCGGCTCGGCG
GTGCCGCCGACGGCCTATGAATGGGGCGGCGGCTGGTATGGCGGCGCCGAGCAGGCCTCGTTCATGCGCGAGAGCCTGAT
GGTCACCGGGCTCGACGAGGTGATGGACTGGCCGGCCGTGTGGAACCCGGACAACCCGTCCTACGAGCGCCTGTGGGGCA
TGATCGGCGCAACCTTCGCGGCCCGCGGCGTGGTCGAGGGGCATGCCTCGGGCCTGCGCGAATTGCCCGAGATTAACGCG
TTCGCGGCCGCCGGCCTCGCCTCCGACCACGAGGTGCAGACGCCGGAAGAGACCTGGGACAAGCTGACCCGCGGCCTGTT
CATCGAGCTGCGCATCTACGCGATGCCCGAGATCATCGGCTGGCTGTTGAAGAAGGGCCTACAGGACTGGTCGCAGATCG
CCTTCACCACCGACGACCGCAGTGCCAGCCATACGCTCGCGCTCGGCGCCAGCGACCACAATGCGCGCGTCGCGATCGAG
GCCGGGCTCGCGCCTGAGATCGCGATCCAGTGTCTCACCATCAATCCCGCGCGCCACATGCGGCTGACGCCGTTCGTCGG
CAGCCTCGCGCCCGGCCGGTTCGGCGACGTCGTGCTGCTGTCGGATGTCGGCAAGCTGGAGATCGCCGAAGTCTGGGCCG
ACGGCGCACAGGTCTCCGAGGGCACGCGCTATCTCGGAGATGTCCCGCGCATCGCCTGGCCGGATTGGGCGACGCAGACC
ATCAACATCAAGCGCGAGATCAAGGCGGAGGATTTCGCGCTGCCGGCCGCGCCGGGGCGCACAACGATGCAGGCGGCGGT
GATCCGTCCGTTCCACTGGCACCCGGAGTTCTACACCTTCGAGCTTGCCGTGCGAGACGGCGCCGTGCAGCGCGACGAGA
GCCAGGCGATCACCAAATTCGCCATCGTCGACCGCTTCTCAGGCGACGGCCTCGTCTCGAAAATGTTCTGGAAGGGTTGC
GGCCCGCGCACGCCGGAAACGGCGCTGGCCTGCTCGGTTGCCCACGACAAGCACAACATCTGGGCGGTCGGCTCCTCGGA
TGCGGCGATGGCCAAGGCGGTCAACGCGCTCGTCGCCCAGCAGGGCGGCTGGGCGCTGGTGCGTGAGGGCGAACTCGCCG
CGACCGTGCGCTTCGAGGTCGGCGGACTGATGAGCTGCCGCCGCGCCGAGGCGCTCGATGCCGAGATGCAGGCGCTCTAC
GCCGAGGGGCGCAAGGTCGACTGGATGTACGAGCCGACGTTCCGGCCGCGCTGGTATCCCGGCTTTCCCGAGCGGCTGAT
GTTCGCGACCCTGACCTGCGCCCCCTGGAGCTGGGTGCTGGTCGCGCCCTGCGAGCAGGCGCCGCAAGGCTTCATCAACG
TGCAGACCGGCAAGACGCATCCGGTGGTCTGGTGA

Upstream 100 bases:

>100_bases
CGCCGCGGCCGCCAGGCAGAGCGGCCCCGCGTCGGCCGAGGCGCCGTCGCGCAAGCGCAGAACCGACAAGCCGAAGGCCT
CGTGACATAGGACGCTCAGC

Downstream 100 bases:

>100_bases
TCAAGGCTGCAACGGCGCAGCAAGGACGGAGATCGCGATGCAGGACATGACGAAGGCGCAGCCAGCTGTGGCTGCCGGCA
GTGCGGCGAACGGATCCACG

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase 1; Adenine aminase 1

Number of amino acids: Translated: 624; Mature: 624

Protein sequence:

>624_residues
MDLAQDIADDLMIDAAQEVRIRQDLVLTALGHRPADRALRVGRLLDVHSRTWSEDQEIVFKGRRIAWVGPAGSYRGEVRE
RVQRPDLAAVPGFGEVHKHIESSHLTPEWEAALVLPRGNTWTCEASHEFSNVNGARNLEFWFEARRRGSPLKIFPQPGSA
VPPTAYEWGGGWYGGAEQASFMRESLMVTGLDEVMDWPAVWNPDNPSYERLWGMIGATFAARGVVEGHASGLRELPEINA
FAAAGLASDHEVQTPEETWDKLTRGLFIELRIYAMPEIIGWLLKKGLQDWSQIAFTTDDRSASHTLALGASDHNARVAIE
AGLAPEIAIQCLTINPARHMRLTPFVGSLAPGRFGDVVLLSDVGKLEIAEVWADGAQVSEGTRYLGDVPRIAWPDWATQT
INIKREIKAEDFALPAAPGRTTMQAAVIRPFHWHPEFYTFELAVRDGAVQRDESQAITKFAIVDRFSGDGLVSKMFWKGC
GPRTPETALACSVAHDKHNIWAVGSSDAAMAKAVNALVAQQGGWALVREGELAATVRFEVGGLMSCRRAEALDAEMQALY
AEGRKVDWMYEPTFRPRWYPGFPERLMFATLTCAPWSWVLVAPCEQAPQGFINVQTGKTHPVVW

Sequences:

>Translated_624_residues
MDLAQDIADDLMIDAAQEVRIRQDLVLTALGHRPADRALRVGRLLDVHSRTWSEDQEIVFKGRRIAWVGPAGSYRGEVRE
RVQRPDLAAVPGFGEVHKHIESSHLTPEWEAALVLPRGNTWTCEASHEFSNVNGARNLEFWFEARRRGSPLKIFPQPGSA
VPPTAYEWGGGWYGGAEQASFMRESLMVTGLDEVMDWPAVWNPDNPSYERLWGMIGATFAARGVVEGHASGLRELPEINA
FAAAGLASDHEVQTPEETWDKLTRGLFIELRIYAMPEIIGWLLKKGLQDWSQIAFTTDDRSASHTLALGASDHNARVAIE
AGLAPEIAIQCLTINPARHMRLTPFVGSLAPGRFGDVVLLSDVGKLEIAEVWADGAQVSEGTRYLGDVPRIAWPDWATQT
INIKREIKAEDFALPAAPGRTTMQAAVIRPFHWHPEFYTFELAVRDGAVQRDESQAITKFAIVDRFSGDGLVSKMFWKGC
GPRTPETALACSVAHDKHNIWAVGSSDAAMAKAVNALVAQQGGWALVREGELAATVRFEVGGLMSCRRAEALDAEMQALY
AEGRKVDWMYEPTFRPRWYPGFPERLMFATLTCAPWSWVLVAPCEQAPQGFINVQTGKTHPVVW
>Mature_624_residues
MDLAQDIADDLMIDAAQEVRIRQDLVLTALGHRPADRALRVGRLLDVHSRTWSEDQEIVFKGRRIAWVGPAGSYRGEVRE
RVQRPDLAAVPGFGEVHKHIESSHLTPEWEAALVLPRGNTWTCEASHEFSNVNGARNLEFWFEARRRGSPLKIFPQPGSA
VPPTAYEWGGGWYGGAEQASFMRESLMVTGLDEVMDWPAVWNPDNPSYERLWGMIGATFAARGVVEGHASGLRELPEINA
FAAAGLASDHEVQTPEETWDKLTRGLFIELRIYAMPEIIGWLLKKGLQDWSQIAFTTDDRSASHTLALGASDHNARVAIE
AGLAPEIAIQCLTINPARHMRLTPFVGSLAPGRFGDVVLLSDVGKLEIAEVWADGAQVSEGTRYLGDVPRIAWPDWATQT
INIKREIKAEDFALPAAPGRTTMQAAVIRPFHWHPEFYTFELAVRDGAVQRDESQAITKFAIVDRFSGDGLVSKMFWKGC
GPRTPETALACSVAHDKHNIWAVGSSDAAMAKAVNALVAQQGGWALVREGELAATVRFEVGGLMSCRRAEALDAEMQALY
AEGRKVDWMYEPTFRPRWYPGFPERLMFATLTCAPWSWVLVAPCEQAPQGFINVQTGKTHPVVW

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family

Homologues:

Organism=Escherichia coli, GI1790098, Length=537, Percent_Identity=30.1675977653631, Blast_Score=174, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADEC1_BRASO (A4YQV7)

Other databases:

- EMBL:   CU234118
- RefSeq:   YP_001204520.1
- ProteinModelPortal:   A4YQV7
- STRING:   A4YQV7
- GeneID:   5119017
- GenomeReviews:   CU234118_GR
- KEGG:   bra:BRADO2460
- eggNOG:   COG1001
- HOGENOM:   HBG299229
- OMA:   FAIVDRF
- ProtClustDB:   CLSK820086
- BioCyc:   BSP376:BRADO2460-MONOMER
- HAMAP:   MF_01518
- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.4.2

Molecular weight: Translated: 69153; Mature: 69153

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLAQDIADDLMIDAAQEVRIRQDLVLTALGHRPADRALRVGRLLDVHSRTWSEDQEIVF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCEEE
KGRRIAWVGPAGSYRGEVRERVQRPDLAAVPGFGEVHKHIESSHLTPEWEAALVLPRGNT
ECCEEEEECCCCCHHHHHHHHHCCCCCEECCCHHHHHHHHHHCCCCCCCCEEEEEECCCE
WTCEASHEFSNVNGARNLEFWFEARRRGSPLKIFPQPGSAVPPTAYEWGGGWYGGAEQAS
EEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCEECCCCCCCCHHHHH
FMRESLMVTGLDEVMDWPAVWNPDNPSYERLWGMIGATFAARGVVEGHASGLRELPEINA
HHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCH
FAAAGLASDHEVQTPEETWDKLTRGLFIELRIYAMPEIIGWLLKKGLQDWSQIAFTTDDR
HHHHCCCCCCCCCCCHHHHHHHHCCEEEEEEEEHHHHHHHHHHHHHHHHHHHEEEEECCC
SASHTLALGASDHNARVAIEAGLAPEIAIQCLTINPARHMRLTPFVGSLAPGRFGDVVLL
CCCEEEEEECCCCCCEEEEECCCCCCCEEEEEEECCHHCEEECCCCCCCCCCCCCCEEEE
SDVGKLEIAEVWADGAQVSEGTRYLGDVPRIAWPDWATQTINIKREIKAEDFALPAAPGR
ECCCCEEEEHHHCCCCHHCCCCHHHCCCCCCCCCCCCCEEEEEEEECCCCCEECCCCCCC
TTMQAAVIRPFHWHPEFYTFELAVRDGAVQRDESQAITKFAIVDRFSGDGLVSKMFWKGC
CHHHHHEECCEECCCCEEEEEEEEECCCCCCCHHHHHHHEEEEECCCCCCHHHHHHHCCC
GPRTPETALACSVAHDKHNIWAVGSSDAAMAKAVNALVAQQGGWALVREGELAATVRFEV
CCCCCCHHEEEEEECCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEEC
GGLMSCRRAEALDAEMQALYAEGRKVDWMYEPTFRPRWYPGFPERLMFATLTCAPWSWVL
CCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHEEEEECCCCCEEE
VAPCEQAPQGFINVQTGKTHPVVW
EECCCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MDLAQDIADDLMIDAAQEVRIRQDLVLTALGHRPADRALRVGRLLDVHSRTWSEDQEIVF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCEEE
KGRRIAWVGPAGSYRGEVRERVQRPDLAAVPGFGEVHKHIESSHLTPEWEAALVLPRGNT
ECCEEEEECCCCCHHHHHHHHHCCCCCEECCCHHHHHHHHHHCCCCCCCCEEEEEECCCE
WTCEASHEFSNVNGARNLEFWFEARRRGSPLKIFPQPGSAVPPTAYEWGGGWYGGAEQAS
EEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCEECCCCCCCCHHHHH
FMRESLMVTGLDEVMDWPAVWNPDNPSYERLWGMIGATFAARGVVEGHASGLRELPEINA
HHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCH
FAAAGLASDHEVQTPEETWDKLTRGLFIELRIYAMPEIIGWLLKKGLQDWSQIAFTTDDR
HHHHCCCCCCCCCCCHHHHHHHHCCEEEEEEEEHHHHHHHHHHHHHHHHHHHEEEEECCC
SASHTLALGASDHNARVAIEAGLAPEIAIQCLTINPARHMRLTPFVGSLAPGRFGDVVLL
CCCEEEEEECCCCCCEEEEECCCCCCCEEEEEEECCHHCEEECCCCCCCCCCCCCCEEEE
SDVGKLEIAEVWADGAQVSEGTRYLGDVPRIAWPDWATQTINIKREIKAEDFALPAAPGR
ECCCCEEEEHHHCCCCHHCCCCHHHCCCCCCCCCCCCCEEEEEEEECCCCCEECCCCCCC
TTMQAAVIRPFHWHPEFYTFELAVRDGAVQRDESQAITKFAIVDRFSGDGLVSKMFWKGC
CHHHHHEECCEECCCCEEEEEEEEECCCCCCCHHHHHHHEEEEECCCCCCHHHHHHHCCC
GPRTPETALACSVAHDKHNIWAVGSSDAAMAKAVNALVAQQGGWALVREGELAATVRFEV
CCCCCCHHEEEEEECCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEEC
GGLMSCRRAEALDAEMQALYAEGRKVDWMYEPTFRPRWYPGFPERLMFATLTCAPWSWVL
CCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHEEEEECCCCCEEE
VAPCEQAPQGFINVQTGKTHPVVW
EECCCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA