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The map label for this gene is xdhA [C]

Identifier: 146339427

GI number: 146339427

Start: 2569145

End: 2571316

Strand: Reverse

Name: xdhA [C]

Synonym: BRADO2413

Alternate gene names: 146339427

Gene position: 2571316-2569145 (Counterclockwise)

Preceding gene: 146339428

Following gene: 146339426

Centisome position: 34.48

GC content: 66.57

Gene sequence:

>2172_bases
GTGACGCCGCGCCTCAACCGCCGCTCCTTCGTCATCGGCACCGCCGCGCTCGGCGGCGGCCTCGCGCTCGGGCTCGACAT
TCCCTTTGGCGGACCTCAGGTGGTCCGCGCGGCCGACGGCTCTCCGGAGGTCAACGCCTGGGTGGTGATCCGCCCAGATG
ACACCGTGGTGATCCGCATCGCCCGCTCCGAGATGGGCCAGGGCTCGCTGACCGGTCTCGCCCAGCTCGTCGCGGAAGAA
CTCGCCTGCGACTGGAGTAAGGTCACTACCGAATATCCGACGCCGGGCCAGAACGTGGCGCGCAAGCGGGTGTGGGGCGA
TTTCTCCACCGGCGGCAGCCGCGGCATCCGCTCGTCGCAGGACTACGTCCGCAAGGGCGGCGCTGCCGCGCGCATGATGC
TGATCCAGGCCGCCGCCGACGAATGGAAGGTGCCGGTGGCGGAATGCACGGCGGCAAACAGCGTCATCACCCACAAGGCG
TCGGGGAAGACCACGACCTACGGCAAGGTCGCGGAAGCCGCCGCCAAGCTTTCGCCGCCGGCCGACGTCAAGCTGAAGGA
TCCGAAGGACTGGACCCTGATCGGCAAGGGCGTGAAGCGCCTCGACACCGCCGACAAGGTCACCGGCGCGATGATCTATG
GCGCCGACATCAAGCTGCCCGGCATGCTCAACGCCGCGATCAAGGACTGCCCGGTCACCGGCGGCAAGCTGAAGAGCTAT
GACGAGGCCAAGATCGCCGGCATGAAGGGCGTCAAGAAGGTGGTCGCGGTCGACGGCACCGCGGTGGCCGTCGTCGCCGA
CACCTGGTGGCACGCGAAGACGGCGCTCGATGCGCTGCCGATCGTGTGGGACGAAGGCCCCAACGCGAAGGTGTCCTCGG
AGTCGATCGGCAAATGGCTCGCGGAAGGCTTGGACTCCGGTCCTGCTTTCGTCGGCAATGAGAACGGCGATGCCAAGGCC
GCGCTGGCCGGCGCGGTGAAGAAGGTCGAGGCGGTCTACAACTATCCCTATCAGAACCACGCCACGATGGAGCCGATGAA
CGCGACCGCGCTCTACACGCCCGAGCGCTGCGAGGTGTGGTGCGGCACGCAGAATGGCGAGGCGGCATTCGCCGCTGTGC
TGGAAGCCTCAGGGCTGCCGGCCGACAAATGCGAGGTGCACAAGCTGATCCTCGGCGGCGGCTTCGGCCGGCGCGGCCAG
ACCGACTACGTCCGCCAGGCCGTGCAGATCGCCAAGGCGATGCCGGGTACGCCGGTCAAGCTGTTGTGGTCGCGCGAGGA
GGACATGACGCATGGCCGCTATCACCCGATCACGCAGTGCAAGCTGACCGGCGGCTTCGACGCCGACAACAACCTGACCG
CGCTGCACATGCGCATCTCCGGCCAGTCGATCCTGTTCAGCCTGCGCCCCGATGCGCTGGTCAACGGCAAGGACCCCGCG
ACCTTCCAGGGGCTTGCGCCCTCGGGCGAGGCGACGATCGGCTATTCCGTGCCGAATTTGCTGATCGAGCACTCCATGCG
CAACCCGCACATCAATCCGGGCTTCTGGCGCGGCGTCAACGTGAACCAGAACGCGATCTATCTCGAATGCTTCATGGATG
AGCTCGCCAATGCCGTCGGCCAGGATCCGCTGGAGTTCCGCCGCAAGCTGATGGCGAAGAATCCGAAGCATCTCGCGGTC
CTCAATGCCGTGGCCGAGAAGATCGGCTGGGGCACGCCGGCGCCGGAGGGCGTGCATCGCGGCCTCGCTCAGTTGCATGG
CTATGGCAGCTATGTCGCGGGTGCGGCCGAGATCTCGGTGATCGACGGCAGCAAGATCAAGGTCCACCGCATCGTCGCGT
CGACCGATCCGGGCTATGTCGTCAACCCGGCGCAGGTCGAGCGGCAGATCGCGGGCTCGTTCGTCTATGGCCTGTCGGCG
CTGTTCTATGGCGGCTGCACGGTGAAGGATGGCCGCATCGAGCAGACCAATTTCGACAGCTACAACTCGATGCGCATCGC
CGAGATGCCGAAGGTGGAAGCGATCATGGTTCCGAGCGGCGGCTTCTGGGGCGGCGTCGGCGAACCGACGATCGGCGTCG
CTGCTCCTGCCGTGCTGAATGCGTTCTTCGCCGCGACCGGCAAACGCATCCGCTCGGTGCCGCTGCGCGACCAGAACATC
ACCTTCGCATGA

Upstream 100 bases:

>100_bases
ACGCCATCACCAACATCTGCCGCTGTGGAACCTTCGCGCAGGTGCGCGAGGCGATCCACGCCGCCGCGAACGCCTGAAGG
AGGCCGGCATGAATCAGCAC

Downstream 100 bases:

>100_bases
TCAGCGTAGCGGCAGCCATTGGGACCAATGGCTGCCGCCGTGCTATTCTCACGCAATGATATCTACCCGCAAGCGTACGC
GCAGAGAGGTCGGCGGCCTG

Product: isoquinoline 1-oxidoreductase subunit beta

Products: NA

Alternate protein names: ALDH [H]

Number of amino acids: Translated: 723; Mature: 722

Protein sequence:

>723_residues
MTPRLNRRSFVIGTAALGGGLALGLDIPFGGPQVVRAADGSPEVNAWVVIRPDDTVVIRIARSEMGQGSLTGLAQLVAEE
LACDWSKVTTEYPTPGQNVARKRVWGDFSTGGSRGIRSSQDYVRKGGAAARMMLIQAAADEWKVPVAECTAANSVITHKA
SGKTTTYGKVAEAAAKLSPPADVKLKDPKDWTLIGKGVKRLDTADKVTGAMIYGADIKLPGMLNAAIKDCPVTGGKLKSY
DEAKIAGMKGVKKVVAVDGTAVAVVADTWWHAKTALDALPIVWDEGPNAKVSSESIGKWLAEGLDSGPAFVGNENGDAKA
ALAGAVKKVEAVYNYPYQNHATMEPMNATALYTPERCEVWCGTQNGEAAFAAVLEASGLPADKCEVHKLILGGGFGRRGQ
TDYVRQAVQIAKAMPGTPVKLLWSREEDMTHGRYHPITQCKLTGGFDADNNLTALHMRISGQSILFSLRPDALVNGKDPA
TFQGLAPSGEATIGYSVPNLLIEHSMRNPHINPGFWRGVNVNQNAIYLECFMDELANAVGQDPLEFRRKLMAKNPKHLAV
LNAVAEKIGWGTPAPEGVHRGLAQLHGYGSYVAGAAEISVIDGSKIKVHRIVASTDPGYVVNPAQVERQIAGSFVYGLSA
LFYGGCTVKDGRIEQTNFDSYNSMRIAEMPKVEAIMVPSGGFWGGVGEPTIGVAAPAVLNAFFAATGKRIRSVPLRDQNI
TFA

Sequences:

>Translated_723_residues
MTPRLNRRSFVIGTAALGGGLALGLDIPFGGPQVVRAADGSPEVNAWVVIRPDDTVVIRIARSEMGQGSLTGLAQLVAEE
LACDWSKVTTEYPTPGQNVARKRVWGDFSTGGSRGIRSSQDYVRKGGAAARMMLIQAAADEWKVPVAECTAANSVITHKA
SGKTTTYGKVAEAAAKLSPPADVKLKDPKDWTLIGKGVKRLDTADKVTGAMIYGADIKLPGMLNAAIKDCPVTGGKLKSY
DEAKIAGMKGVKKVVAVDGTAVAVVADTWWHAKTALDALPIVWDEGPNAKVSSESIGKWLAEGLDSGPAFVGNENGDAKA
ALAGAVKKVEAVYNYPYQNHATMEPMNATALYTPERCEVWCGTQNGEAAFAAVLEASGLPADKCEVHKLILGGGFGRRGQ
TDYVRQAVQIAKAMPGTPVKLLWSREEDMTHGRYHPITQCKLTGGFDADNNLTALHMRISGQSILFSLRPDALVNGKDPA
TFQGLAPSGEATIGYSVPNLLIEHSMRNPHINPGFWRGVNVNQNAIYLECFMDELANAVGQDPLEFRRKLMAKNPKHLAV
LNAVAEKIGWGTPAPEGVHRGLAQLHGYGSYVAGAAEISVIDGSKIKVHRIVASTDPGYVVNPAQVERQIAGSFVYGLSA
LFYGGCTVKDGRIEQTNFDSYNSMRIAEMPKVEAIMVPSGGFWGGVGEPTIGVAAPAVLNAFFAATGKRIRSVPLRDQNI
TFA
>Mature_722_residues
TPRLNRRSFVIGTAALGGGLALGLDIPFGGPQVVRAADGSPEVNAWVVIRPDDTVVIRIARSEMGQGSLTGLAQLVAEEL
ACDWSKVTTEYPTPGQNVARKRVWGDFSTGGSRGIRSSQDYVRKGGAAARMMLIQAAADEWKVPVAECTAANSVITHKAS
GKTTTYGKVAEAAAKLSPPADVKLKDPKDWTLIGKGVKRLDTADKVTGAMIYGADIKLPGMLNAAIKDCPVTGGKLKSYD
EAKIAGMKGVKKVVAVDGTAVAVVADTWWHAKTALDALPIVWDEGPNAKVSSESIGKWLAEGLDSGPAFVGNENGDAKAA
LAGAVKKVEAVYNYPYQNHATMEPMNATALYTPERCEVWCGTQNGEAAFAAVLEASGLPADKCEVHKLILGGGFGRRGQT
DYVRQAVQIAKAMPGTPVKLLWSREEDMTHGRYHPITQCKLTGGFDADNNLTALHMRISGQSILFSLRPDALVNGKDPAT
FQGLAPSGEATIGYSVPNLLIEHSMRNPHINPGFWRGVNVNQNAIYLECFMDELANAVGQDPLEFRRKLMAKNPKHLAVL
NAVAEKIGWGTPAPEGVHRGLAQLHGYGSYVAGAAEISVIDGSKIKVHRIVASTDPGYVVNPAQVERQIAGSFVYGLSAL
FYGGCTVKDGRIEQTNFDSYNSMRIAEMPKVEAIMVPSGGFWGGVGEPTIGVAAPAVLNAFFAATGKRIRSVPLRDQNIT
FA

Specific function: Presumed To Be A Dehydrogenase, But Possibly An Oxidase. Participates In Limited Purine Salvage (Requires Aspartate) But Does Not Support Aerobic Growth On Purines As The Sole Carbon Source (Purine Catabolism). Deletion Results In Increased Adenine Sensit

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789230, Length=404, Percent_Identity=23.2673267326733, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.3 [H]

Molecular weight: Translated: 76921; Mature: 76789

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPRLNRRSFVIGTAALGGGLALGLDIPFGGPQVVRAADGSPEVNAWVVIRPDDTVVIRI
CCCCCCCCEEEEEEEECCCCEEEEEECCCCCCEEEEECCCCCCCEEEEEECCCCEEEEEE
ARSEMGQGSLTGLAQLVAEELACDWSKVTTEYPTPGQNVARKRVWGDFSTGGSRGIRSSQ
ECCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCH
DYVRKGGAAARMMLIQAAADEWKVPVAECTAANSVITHKASGKTTTYGKVAEAAAKLSPP
HHHHCCCHHHHHHHHHHHHCCCCCCHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHCCCC
ADVKLKDPKDWTLIGKGVKRLDTADKVTGAMIYGADIKLPGMLNAAIKDCPVTGGKLKSY
CCEEECCCCCEEEEHHHHHHHCCHHHHCEEEEEECCEECCCHHHHHHHCCCCCCCCCCCC
DEAKIAGMKGVKKVVAVDGTAVAVVADTWWHAKTALDALPIVWDEGPNAKVSSESIGKWL
CHHHHHHHHHHHEEEEECCCEEEEEECCCHHHHHHHHCCCEEECCCCCCCCCHHHHHHHH
AEGLDSGPAFVGNENGDAKAALAGAVKKVEAVYNYPYQNHATMEPMNATALYTPERCEVW
HHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEE
CGTQNGEAAFAAVLEASGLPADKCEVHKLILGGGFGRRGQTDYVRQAVQIAKAMPGTPVK
ECCCCCCHHHHHHHHHCCCCCCHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEE
LLWSREEDMTHGRYHPITQCKLTGGFDADNNLTALHMRISGQSILFSLRPDALVNGKDPA
EEECCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEECCCEEEEEECCCCEECCCCCC
TFQGLAPSGEATIGYSVPNLLIEHSMRNPHINPGFWRGVNVNQNAIYLECFMDELANAVG
EECCCCCCCCEEECCCHHHHHHHHCCCCCCCCCCCEECCCCCCCEEEHHHHHHHHHHHHC
QDPLEFRRKLMAKNPKHLAVLNAVAEKIGWGTPAPEGVHRGLAQLHGYGSYVAGAAEISV
CCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEECCCEEEEE
IDGSKIKVHRIVASTDPGYVVNPAQVERQIAGSFVYGLSALFYGGCTVKDGRIEQTNFDS
ECCCEEEEEEEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCC
YNSMRIAEMPKVEAIMVPSGGFWGGVGEPTIGVAAPAVLNAFFAATGKRIRSVPLRDQNI
CCCEEEECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHEECCCCCCCC
TFA
CCC
>Mature Secondary Structure 
TPRLNRRSFVIGTAALGGGLALGLDIPFGGPQVVRAADGSPEVNAWVVIRPDDTVVIRI
CCCCCCCEEEEEEEECCCCEEEEEECCCCCCEEEEECCCCCCCEEEEEECCCCEEEEEE
ARSEMGQGSLTGLAQLVAEELACDWSKVTTEYPTPGQNVARKRVWGDFSTGGSRGIRSSQ
ECCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCH
DYVRKGGAAARMMLIQAAADEWKVPVAECTAANSVITHKASGKTTTYGKVAEAAAKLSPP
HHHHCCCHHHHHHHHHHHHCCCCCCHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHCCCC
ADVKLKDPKDWTLIGKGVKRLDTADKVTGAMIYGADIKLPGMLNAAIKDCPVTGGKLKSY
CCEEECCCCCEEEEHHHHHHHCCHHHHCEEEEEECCEECCCHHHHHHHCCCCCCCCCCCC
DEAKIAGMKGVKKVVAVDGTAVAVVADTWWHAKTALDALPIVWDEGPNAKVSSESIGKWL
CHHHHHHHHHHHEEEEECCCEEEEEECCCHHHHHHHHCCCEEECCCCCCCCCHHHHHHHH
AEGLDSGPAFVGNENGDAKAALAGAVKKVEAVYNYPYQNHATMEPMNATALYTPERCEVW
HHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEE
CGTQNGEAAFAAVLEASGLPADKCEVHKLILGGGFGRRGQTDYVRQAVQIAKAMPGTPVK
ECCCCCCHHHHHHHHHCCCCCCHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEE
LLWSREEDMTHGRYHPITQCKLTGGFDADNNLTALHMRISGQSILFSLRPDALVNGKDPA
EEECCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEECCCEEEEEECCCCEECCCCCC
TFQGLAPSGEATIGYSVPNLLIEHSMRNPHINPGFWRGVNVNQNAIYLECFMDELANAVG
EECCCCCCCCEEECCCHHHHHHHHCCCCCCCCCCCEECCCCCCCEEEHHHHHHHHHHHHC
QDPLEFRRKLMAKNPKHLAVLNAVAEKIGWGTPAPEGVHRGLAQLHGYGSYVAGAAEISV
CCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEECCCEEEEE
IDGSKIKVHRIVASTDPGYVVNPAQVERQIAGSFVYGLSALFYGGCTVKDGRIEQTNFDS
ECCCEEEEEEEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCC
YNSMRIAEMPKVEAIMVPSGGFWGGVGEPTIGVAAPAVLNAFFAATGKRIRSVPLRDQNI
CCCEEEECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHEECCCCCCCC
TFA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2606906 [H]