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The map label for this gene is tlpA [H]

Identifier: 146339418

GI number: 146339418

Start: 2563084

End: 2563575

Strand: Reverse

Name: tlpA [H]

Synonym: BRADO2404

Alternate gene names: 146339418

Gene position: 2563575-2563084 (Counterclockwise)

Preceding gene: 146339419

Following gene: 146339414

Centisome position: 34.38

GC content: 68.09

Gene sequence:

>492_bases
ATGTTTCGCAGCGGCCGCAGCCAGTTCATCGTCGAGCGGCCGCGCAATCCGCTGCCGGCGCTGAAGCTGCAGGACATCAG
CGGCAAGGACGTCACGCTCGCGCCGACGTCCGGCCATGTCACGCTGGTCAATCTCTGGGCCACCTGGTGCGCGGCCTGCA
AGATCGACCTGCCGACGCTCGCCGCGCTGGAGCGCGCGCGGATGCCGGGGCTCGACATCTGGACCATCTGCACCGACCGC
CGCGACATCAAGACGATCCGCCGCTATGCTGAGGCGATCGCGATGCCCCGCTCCTCCTTCTCCGATCCGCATGCGCAGGC
GACCAACCCGGCCAACGCCGAGGCCTCCCTCTTCGCCACGCCGGCAATGCCGATCACCTATCTGATCGGGACGAGCGGCT
TGATCGAGGGCTATGTCACAGGCGCGGCCGAATGGCTGTCGGATCCCGGCCAGGCCCTGCTGCGCTACTATCTCGATCAG
CCGGCGGCGTGA

Upstream 100 bases:

>100_bases
CAGCGCGCTCACGCGTCGTGCGGCGCTGCTCGGAGCCGCGAGCACCCTTGTCGTGTCCTCGTCCCCAGCCCACGCCGCCG
CTGGCGATCCGAGCCCGCCG

Downstream 100 bases:

>100_bases
TTGGCGGAAGGCGTCACGAACGCTGATCGCGAGCATTCTCCATCAAGACCCCATCACTCCGCCGCGCGATCAAATACGAG
GGAGCAAACTTTACAACTCG

Product: putative thiol-disulfide oxidoreductase

Products: NA

Alternate protein names: Cytochrome c biogenesis protein tlpA [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MFRSGRSQFIVERPRNPLPALKLQDISGKDVTLAPTSGHVTLVNLWATWCAACKIDLPTLAALERARMPGLDIWTICTDR
RDIKTIRRYAEAIAMPRSSFSDPHAQATNPANAEASLFATPAMPITYLIGTSGLIEGYVTGAAEWLSDPGQALLRYYLDQ
PAA

Sequences:

>Translated_163_residues
MFRSGRSQFIVERPRNPLPALKLQDISGKDVTLAPTSGHVTLVNLWATWCAACKIDLPTLAALERARMPGLDIWTICTDR
RDIKTIRRYAEAIAMPRSSFSDPHAQATNPANAEASLFATPAMPITYLIGTSGLIEGYVTGAAEWLSDPGQALLRYYLDQ
PAA
>Mature_163_residues
MFRSGRSQFIVERPRNPLPALKLQDISGKDVTLAPTSGHVTLVNLWATWCAACKIDLPTLAALERARMPGLDIWTICTDR
RDIKTIRRYAEAIAMPRSSFSDPHAQATNPANAEASLFATPAMPITYLIGTSGLIEGYVTGAAEWLSDPGQALLRYYLDQ
PAA

Specific function: Involved in cytochrome aa3 assembly [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 17831; Mature: 17831

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRSGRSQFIVERPRNPLPALKLQDISGKDVTLAPTSGHVTLVNLWATWCAACKIDLPTL
CCCCCCCCEEEECCCCCCCCEEEECCCCCEEEEECCCCCEEEHHHHHHHHHHHCCCCHHH
AALERARMPGLDIWTICTDRRDIKTIRRYAEAIAMPRSSFSDPHAQATNPANAEASLFAT
HHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEC
PAMPITYLIGTSGLIEGYVTGAAEWLSDPGQALLRYYLDQPAA
CCCCEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFRSGRSQFIVERPRNPLPALKLQDISGKDVTLAPTSGHVTLVNLWATWCAACKIDLPTL
CCCCCCCCEEEECCCCCCCCEEEECCCCCEEEEECCCCCEEEHHHHHHHHHHHCCCCHHH
AALERARMPGLDIWTICTDRRDIKTIRRYAEAIAMPRSSFSDPHAQATNPANAEASLFAT
HHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEC
PAMPITYLIGTSGLIEGYVTGAAEWLSDPGQALLRYYLDQPAA
CCCCEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8253065; 12597275 [H]