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The map label for this gene is nahR [H]

Identifier: 146339393

GI number: 146339393

Start: 2532158

End: 2533177

Strand: Reverse

Name: nahR [H]

Synonym: BRADO2378

Alternate gene names: 146339393

Gene position: 2533177-2532158 (Counterclockwise)

Preceding gene: 146339396

Following gene: 146339389

Centisome position: 33.97

GC content: 68.63

Gene sequence:

>1020_bases
TTGATCTGGATCAAACGCGGCGTGGTCCGTGCCCGCCAGTATCGTCAGGAGACACCGCCGATCAAGGCCATCAGGCCGAT
CCGATCCATGAGCCAATTCGATCATTTGGACCTCGACGGCCACCTGCTGCAGCTGCTGCTCGCCGTGATCGAGGAGGGCT
CGGTGACGCGCGCCGCGCATCGGCTCGGCGTGACGCAATCGGCCGTCAGCCATCTGCTGGACAAGCTGCGCGCCATCACC
GGCGATCCGCTGTTCGTGAAATCGGGCCGCGGCATCGTCCCGACGGCGCATGCGCAGCTGCTCGCCTTGCGCGCCCGAGC
GCTGCTCGACGACCTCCGCAGCTTCTCGCATGCCGCCGCCTTCGAACCGGCCAAGATCTCCGCGCAGGTCACGATCGCCG
CCAACGATCTGCAGCGCGATCTGCTGCTGCCGTCCCTGCTGCGCTATGCGCGCGCGCAAGCGCCCGGTCTCAGCCTGCGC
GTGATCCAATCAGGCGCGCCGACACCGGAGATGCTGCGTGAGGAGCACTGCCAGCTCATGATCACGCCGCGCCCGCCCGA
GGGCAGCGACATCATGCAGAAGCGGCTGTTCGAGGACAGCTACCGCGTGTTCTACGATGCCAGCCAGCGCGAGCCGCCGC
GCAGCCTGGACGAGTATCTCGCAAGCGATCATGTTACCGTCGTCTATGAGCCGCGCCGCCGGCTCGACATCGATGAGGTG
CTGGCCGAGCGCGGCCTCGTCAGGCGCTTCGTCGCGCAGGTTCCGGGCTTCGGCGGCATCGGCCCATTCCTGCGCGGCAG
CCGCATCATCGCGACGTTGCCGGGTCTGCTGCGCGCCTACATGCTGCGCGGCCTCGCCATCGCTCCGGTGCCGGTCCCCT
GCCCCGTCATGCCGATGTACATGGTCTGGCACCTGCGCCACCACGACGATCCTCTGCACCGCTGGCTGCGCCAGCAGCTC
GAGATCGTGGCCGCGCCGAGCCTCGCCGCGGCGGCCGAGCACATGCCGGCCGTCGCGTAG

Upstream 100 bases:

>100_bases
GGCCTGCTCGCCGTCGAAGATTGTGGTGCCGGGCACAGGCTGCCGGGCCGATGTGGCGGACATTGGGTCCCTCCCCTGAA
AGCGTTCTGACGGGCCGCGT

Downstream 100 bases:

>100_bases
TCGTTCAGTCTGCGCAGCTCAGCGCAGGATCTTGTGCAGCACCTCGCCATCGACCTGCTGCGGCTTGACGCCGAGGATCC
GCATGATGGTCGGCGCCACG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MIWIKRGVVRARQYRQETPPIKAIRPIRSMSQFDHLDLDGHLLQLLLAVIEEGSVTRAAHRLGVTQSAVSHLLDKLRAIT
GDPLFVKSGRGIVPTAHAQLLALRARALLDDLRSFSHAAAFEPAKISAQVTIAANDLQRDLLLPSLLRYARAQAPGLSLR
VIQSGAPTPEMLREEHCQLMITPRPPEGSDIMQKRLFEDSYRVFYDASQREPPRSLDEYLASDHVTVVYEPRRRLDIDEV
LAERGLVRRFVAQVPGFGGIGPFLRGSRIIATLPGLLRAYMLRGLAIAPVPVPCPVMPMYMVWHLRHHDDPLHRWLRQQL
EIVAAPSLAAAAEHMPAVA

Sequences:

>Translated_339_residues
MIWIKRGVVRARQYRQETPPIKAIRPIRSMSQFDHLDLDGHLLQLLLAVIEEGSVTRAAHRLGVTQSAVSHLLDKLRAIT
GDPLFVKSGRGIVPTAHAQLLALRARALLDDLRSFSHAAAFEPAKISAQVTIAANDLQRDLLLPSLLRYARAQAPGLSLR
VIQSGAPTPEMLREEHCQLMITPRPPEGSDIMQKRLFEDSYRVFYDASQREPPRSLDEYLASDHVTVVYEPRRRLDIDEV
LAERGLVRRFVAQVPGFGGIGPFLRGSRIIATLPGLLRAYMLRGLAIAPVPVPCPVMPMYMVWHLRHHDDPLHRWLRQQL
EIVAAPSLAAAAEHMPAVA
>Mature_339_residues
MIWIKRGVVRARQYRQETPPIKAIRPIRSMSQFDHLDLDGHLLQLLLAVIEEGSVTRAAHRLGVTQSAVSHLLDKLRAIT
GDPLFVKSGRGIVPTAHAQLLALRARALLDDLRSFSHAAAFEPAKISAQVTIAANDLQRDLLLPSLLRYARAQAPGLSLR
VIQSGAPTPEMLREEHCQLMITPRPPEGSDIMQKRLFEDSYRVFYDASQREPPRSLDEYLASDHVTVVYEPRRRLDIDEV
LAERGLVRRFVAQVPGFGGIGPFLRGSRIIATLPGLLRAYMLRGLAIAPVPVPCPVMPMYMVWHLRHHDDPLHRWLRQQL
EIVAAPSLAAAAEHMPAVA

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=296, Percent_Identity=24.3243243243243, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788626, Length=176, Percent_Identity=30.6818181818182, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 37910; Mature: 37910

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIWIKRGVVRARQYRQETPPIKAIRPIRSMSQFDHLDLDGHLLQLLLAVIEEGSVTRAAH
CCEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHH
RLGVTQSAVSHLLDKLRAITGDPLFVKSGRGIVPTAHAQLLALRARALLDDLRSFSHAAA
HHCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
FEPAKISAQVTIAANDLQRDLLLPSLLRYARAQAPGLSLRVIQSGAPTPEMLREEHCQLM
CCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHCCEEE
ITPRPPEGSDIMQKRLFEDSYRVFYDASQREPPRSLDEYLASDHVTVVYEPRRRLDIDEV
EECCCCCCHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHCCCEEEEECCHHHCCHHHH
LAERGLVRRFVAQVPGFGGIGPFLRGSRIIATLPGLLRAYMLRGLAIAPVPVPCPVMPMY
HHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHH
MVWHLRHHDDPLHRWLRQQLEIVAAPSLAAAAEHMPAVA
HHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MIWIKRGVVRARQYRQETPPIKAIRPIRSMSQFDHLDLDGHLLQLLLAVIEEGSVTRAAH
CCEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHH
RLGVTQSAVSHLLDKLRAITGDPLFVKSGRGIVPTAHAQLLALRARALLDDLRSFSHAAA
HHCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
FEPAKISAQVTIAANDLQRDLLLPSLLRYARAQAPGLSLRVIQSGAPTPEMLREEHCQLM
CCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHCCEEE
ITPRPPEGSDIMQKRLFEDSYRVFYDASQREPPRSLDEYLASDHVTVVYEPRRRLDIDEV
EECCCCCCHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHCCCEEEEECCHHHCCHHHH
LAERGLVRRFVAQVPGFGGIGPFLRGSRIIATLPGLLRAYMLRGLAIAPVPVPCPVMPMY
HHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHH
MVWHLRHHDDPLHRWLRQQLEIVAAPSLAAAAEHMPAVA
HHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]