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The map label for this gene is ligK [H]

Identifier: 146339357

GI number: 146339357

Start: 2491558

End: 2492253

Strand: Direct

Name: ligK [H]

Synonym: BRADO2338

Alternate gene names: 146339357

Gene position: 2491558-2492253 (Clockwise)

Preceding gene: 146339356

Following gene: 146339358

Centisome position: 33.41

GC content: 66.52

Gene sequence:

>696_bases
ATGAGCACCCCCATGAACAATCTCGGCATCGTCAAGACCAAGATCACCCGCGCCGACAAGGCGGCGGTGGAGAAGCTGTC
CAAGTTCGGCGTCGCCACCATTCACGAGGCGATGGGCCGGGTCGGCCTGATGCAGTGCTACATGCGTCCGATCTATCCGA
CGGCAAAGATGTGCGGCACTGCCGTCACCGTGCTGCTTCAGCCCGGCGACAACTGGATGCTGCATGTCGCGGCCGAGCAG
ATCCAGCCCGGCGACGTCGTCGTCGCGGCCTGCACGGTGGAGAACACCGACGGCTTCTTCGGCGATCTCCTGGCCACCAG
TTTTCGCGCGCGCGGTGCGCAGGGTCTGGTCATCGACGGCGGCGTCCGTGACGTCGCCGATCTCACGGAGATGCAGTTCC
CGGTTTTCTCGCGCGCGATCAGCGCCCGCGGCACGGTGAAGGCGACGCTCGGCTCGGTCAACATCCCGATCGTCTGCGCC
GGGGCCGCGGTTAATCCTGGTGACGTGATCGTCGCCGATGTCGACGGCATCGTCGTGGTGCCGGCTGCGGTCGCGCATCA
GGCGGCGGACGCCGCGGCGGCGCGCGAGGCCAACGAGGCCGACAAGCGCGAGAAGCTGGCGTCGGGCGTGCTCGGTCTCG
ACATGTACAAGATGCGCGAGCCGCTGGCGAAGGCCGGGCTCAAATATATCGATTGA

Upstream 100 bases:

>100_bases
CCCGAGCAGCGCCACCAGATCTACGAAGGCAACGCCCGGCGCGTGTTCCCGCGTCTCGACGCCGCGTTGAAGGCCAAGGG
CAAGTAATCTAAAGCGAGCC

Downstream 100 bases:

>100_bases
GCGATGACGGCGGCGTCCAACCAGTGGCATGTCGGGCTGATCGGCTACGGCGAGGTCGGCAAGATCCTCGCCGAGGATCT
GCGCAAGGACGGCGTTGATG

Product: hypothetical protein

Products: NA

Alternate protein names: 4-hydroxy-2-oxoglutarate aldolase [H]

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MSTPMNNLGIVKTKITRADKAAVEKLSKFGVATIHEAMGRVGLMQCYMRPIYPTAKMCGTAVTVLLQPGDNWMLHVAAEQ
IQPGDVVVAACTVENTDGFFGDLLATSFRARGAQGLVIDGGVRDVADLTEMQFPVFSRAISARGTVKATLGSVNIPIVCA
GAAVNPGDVIVADVDGIVVVPAAVAHQAADAAAAREANEADKREKLASGVLGLDMYKMREPLAKAGLKYID

Sequences:

>Translated_231_residues
MSTPMNNLGIVKTKITRADKAAVEKLSKFGVATIHEAMGRVGLMQCYMRPIYPTAKMCGTAVTVLLQPGDNWMLHVAAEQ
IQPGDVVVAACTVENTDGFFGDLLATSFRARGAQGLVIDGGVRDVADLTEMQFPVFSRAISARGTVKATLGSVNIPIVCA
GAAVNPGDVIVADVDGIVVVPAAVAHQAADAAAAREANEADKREKLASGVLGLDMYKMREPLAKAGLKYID
>Mature_230_residues
STPMNNLGIVKTKITRADKAAVEKLSKFGVATIHEAMGRVGLMQCYMRPIYPTAKMCGTAVTVLLQPGDNWMLHVAAEQI
QPGDVVVAACTVENTDGFFGDLLATSFRARGAQGLVIDGGVRDVADLTEMQFPVFSRAISARGTVKATLGSVNIPIVCAG
AAVNPGDVIVADVDGIVVVPAAVAHQAADAAAAREANEADKREKLASGVLGLDMYKMREPLAKAGLKYID

Specific function: Plays a role in protocatechuate degradation. Has a broad substrate specificity and catalyzes the aldol cleavage of 4- hydroxy-4-methyl-2-oxoglutarate, 4-hydroxy-2-oxoglutarate and 4- carboxy-4-hydroxy-2-oxoadipate, and the decarboxylation of oxaloacetate.

COG id: COG0684

COG function: function code H; Demethylmenaquinone methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014165
- InterPro:   IPR005493 [H]

Pfam domain/function: PF03737 Methyltransf_6 [H]

EC number: =4.1.1.3; =4.1.3.16; =4.1.3.17 [H]

Molecular weight: Translated: 24213; Mature: 24082

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPMNNLGIVKTKITRADKAAVEKLSKFGVATIHEAMGRVGLMQCYMRPIYPTAKMCGT
CCCCCCCCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCC
AVTVLLQPGDNWMLHVAAEQIQPGDVVVAACTVENTDGFFGDLLATSFRARGAQGLVIDG
EEEEEEECCCCEEEEEEECCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEC
GVRDVADLTEMQFPVFSRAISARGTVKATLGSVNIPIVCAGAAVNPGDVIVADVDGIVVV
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCCCCCEEEECCCCEEEE
PAAVAHQAADAAAAREANEADKREKLASGVLGLDMYKMREPLAKAGLKYID
CHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
STPMNNLGIVKTKITRADKAAVEKLSKFGVATIHEAMGRVGLMQCYMRPIYPTAKMCGT
CCCCCCCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCC
AVTVLLQPGDNWMLHVAAEQIQPGDVVVAACTVENTDGFFGDLLATSFRARGAQGLVIDG
EEEEEEECCCCEEEEEEECCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEC
GVRDVADLTEMQFPVFSRAISARGTVKATLGSVNIPIVCAGAAVNPGDVIVADVDGIVVV
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCCCCCEEEECCCCEEEE
PAAVAHQAADAAAAREANEADKREKLASGVLGLDMYKMREPLAKAGLKYID
CHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11826967 [H]