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The map label for this gene is namA [H]

Identifier: 146339341

GI number: 146339341

Start: 2473795

End: 2476155

Strand: Direct

Name: namA [H]

Synonym: BRADO2322

Alternate gene names: 146339341

Gene position: 2473795-2476155 (Clockwise)

Preceding gene: 146339340

Following gene: 146339342

Centisome position: 33.18

GC content: 64.38

Gene sequence:

>2361_bases
GTGGAGGCGCTCATGAAGATCGCGATCATCGGCGGCGGACCTGCCGGTCTCTATGCGGCGATATTGCTCAAGAAGCAGCG
GCCCAAGGCCGACATCGCGGTCTACGAACGCAACCGTGCCGACGATACGTTCGGCTTCGGCGTGGTGTTCTCCGACGCCA
CGCTCGATAATTTCGAAAAGAACGACCTGCCGAGCTACCAGCGCATAACCCAGGAGTTCGCCTACTGGGATGACATCGCC
GTGCACTTCCGCGGCACGGTGCACCGCGTCGGCGGCAACGGCTTCTGCGGCTGCTCGCGCCGCACGCTGTTGCGAATTCT
GCAGGAGCGCGCACGCGAGCTCGGCGTCACCTTGCAGTTCGAGGTCGATCTCGAAGAGGAGACGCAGTTTGCGGATGCCG
ATCTGCTGATCCTGTCGGACGGCATCAATAGCCGCTTCCGCCAGAAGTATGTCGATCATTTCCAGCCCGAGGTGGACCTG
CGCGCCAACAAGTTTGCGTGGATGGGCTCGACCAAGCCGCTCGACGCCTTCACCTTCATCTTCCAGGAGACGGAGTGGGG
CCCGTTCATCGCCCACGCCTATCAATACGAGGCGGGGCACTCGACCTGGATCTTCGAGACCGATCCGCGGACGTTCGAGA
AAGCCGGCCTGACTGGGCTCGACGAGCGGCAATCCGCCGACCGCATGAAGGACATCTTCGGCTGGTTTCTCGGCGATCAC
CCGCTGCTGATCAACCGCTCTATGTGGCGCAATTTCCCGATGATCCGCAACAAGCGCTGGGTCAAGGACAACATGGTACT
GCTCGGCGACGCCAAGTCGACCGCGCATTTCTCGATCGGCTCGGGCACCAAGCTCGCGATGGAGGATGCCATCGCGCTGG
CCGACGCCATGCAGCGGGCACCGACCATTCCAGCGGCGCTCGATCTCTATGAGCACGGCCGGCGCGAGGAGGTCGAGAAG
ACCCAGCACGCCGCGGACGTGTCGCTGGTCTGGTTCGAGCATGTCGACCGCTTCTGGGATTTCGATCCCGTGCAGTTCGC
GTTCGGCGTGATGACACGCTCGAAGGCGATCACCTACGACAATCTCACCTTGCGCGCGCCGGATTTCGTCGCCGAAGTCG
ACAAGTCGTTCGCGCGCCAAGTGCGATCCACGGGTTTCGATGTCGATGTCGACAAACCGGTCGCGCCAATGTTCCAGCCG
CTCAAGCTGCGCGAGATGACGCTCGCCAATCGCGCGGTGCTTTCGCCAATGTGCATGTACTCGGCCGCGGAGGGCGTGCC
AGGCGACTTCCATCTCGTGCATTACGGCTCGCGCGCGATCGGCGGCGCCGGCCTGCTGTTCACCGAGATGACCTGCGTCA
GCCGCGATGCCCGTATCACGCCTGGCTGCGCCGGTTTGTGGAACGACGTGCAGGAAGCGGCCTGGAAGCGCATCGTTGAT
TTCGTGCACGCCAACTCGCAGGCGAAGTTCGCGCTGCAGGTCGGTCATGCCGGCCGCAAGGGCGCGACCAGGCTGATGTG
GGACGGCATGGACCGTCCGCTGGAGCAGGGTGGCTGGGATGTCGTCTCGGCATCGCCGCTGCCTTACTTCCCCGACAGCC
AGGTGCCGCGCGAACTCGACCGCGTGTCGATGGATGCGATCAAGGCCGACTTCGTTGCGGCGGCCGAGCGCGGTCACCGT
TGCGGCTTCGACATGCTCGAACTGCATTGCGCCCACGGCTATCTGCTCGCGAGCTTCATCTCGCCGCTGACCAACAAGCG
GACCGATCAGTACGGCGGTTCGCTGGAGAACCGGCTGCGCTTTCCGCTCGAAGTCTTCGCGGCGATGCGCGCGGCGTGGC
CGGCGCACAAGCCGATGTCGGTGCGCATCTCCGCAACCGATTGGGCCGAGGGCGGCATCACCGGCGATGATGCCGTGCGG
ATCGCCCGCGCGTTCGGCGAGGCGGGGGTCGATCTCGTCGACGTCTCCACCGGCCAGACCGTGCGCGAGGCCCGGCCGAT
CTACGGCCGTATGTTCCAGACGCCGTTCTCCGATCAGGTCCGTAACGAGGCCCATGTTGCCACGATGTGCGTCGGCAACA
TCACCACTGCAGACCAGGTCAACACCATCCTCGCCGCCGGCCGCGCCGATCTCGTCGCGCTCGGCCGTCCGCATCTGGTC
GATCCGGCCTTCACCATGAAGGCTGCCGCCTGGTACGGCGCGGACATGTTCTGTCCGCCGCAATATCTGCCGGGTAAGGA
GCAGATCTTCCGCAACAGCGTGCGCGAGCGGCAGGATTTCGAGGAGCTGAAGATTAAGGCTAAACCGAAGACTCGGGCGG
AGCTGAAGGCCGAGGCTGCGAAGCCGCTTGCGGCGGAGTAA

Upstream 100 bases:

>100_bases
GAAGCCGGTCTTCCAGGGGAATTGAGCAGCTGTAGGAACCGAAGGGGCTTGCCAGGAAATATTTTAGGTCTAAAATAATT
TCCATTGGCTCGGCTCTCCA

Downstream 100 bases:

>100_bases
GCCGCTGTGCCACGCTGCCGCCCGGTACGTCCAATGTAGGTGGAGTAGGGGACGATGAAGGCGATCATCGTGGGCGGCGG
TATCGGCGGATTGACCACGG

Product: NADPH dehydrogenase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 786; Mature: 786

Protein sequence:

>786_residues
MEALMKIAIIGGGPAGLYAAILLKKQRPKADIAVYERNRADDTFGFGVVFSDATLDNFEKNDLPSYQRITQEFAYWDDIA
VHFRGTVHRVGGNGFCGCSRRTLLRILQERARELGVTLQFEVDLEEETQFADADLLILSDGINSRFRQKYVDHFQPEVDL
RANKFAWMGSTKPLDAFTFIFQETEWGPFIAHAYQYEAGHSTWIFETDPRTFEKAGLTGLDERQSADRMKDIFGWFLGDH
PLLINRSMWRNFPMIRNKRWVKDNMVLLGDAKSTAHFSIGSGTKLAMEDAIALADAMQRAPTIPAALDLYEHGRREEVEK
TQHAADVSLVWFEHVDRFWDFDPVQFAFGVMTRSKAITYDNLTLRAPDFVAEVDKSFARQVRSTGFDVDVDKPVAPMFQP
LKLREMTLANRAVLSPMCMYSAAEGVPGDFHLVHYGSRAIGGAGLLFTEMTCVSRDARITPGCAGLWNDVQEAAWKRIVD
FVHANSQAKFALQVGHAGRKGATRLMWDGMDRPLEQGGWDVVSASPLPYFPDSQVPRELDRVSMDAIKADFVAAAERGHR
CGFDMLELHCAHGYLLASFISPLTNKRTDQYGGSLENRLRFPLEVFAAMRAAWPAHKPMSVRISATDWAEGGITGDDAVR
IARAFGEAGVDLVDVSTGQTVREARPIYGRMFQTPFSDQVRNEAHVATMCVGNITTADQVNTILAAGRADLVALGRPHLV
DPAFTMKAAAWYGADMFCPPQYLPGKEQIFRNSVRERQDFEELKIKAKPKTRAELKAEAAKPLAAE

Sequences:

>Translated_786_residues
MEALMKIAIIGGGPAGLYAAILLKKQRPKADIAVYERNRADDTFGFGVVFSDATLDNFEKNDLPSYQRITQEFAYWDDIA
VHFRGTVHRVGGNGFCGCSRRTLLRILQERARELGVTLQFEVDLEEETQFADADLLILSDGINSRFRQKYVDHFQPEVDL
RANKFAWMGSTKPLDAFTFIFQETEWGPFIAHAYQYEAGHSTWIFETDPRTFEKAGLTGLDERQSADRMKDIFGWFLGDH
PLLINRSMWRNFPMIRNKRWVKDNMVLLGDAKSTAHFSIGSGTKLAMEDAIALADAMQRAPTIPAALDLYEHGRREEVEK
TQHAADVSLVWFEHVDRFWDFDPVQFAFGVMTRSKAITYDNLTLRAPDFVAEVDKSFARQVRSTGFDVDVDKPVAPMFQP
LKLREMTLANRAVLSPMCMYSAAEGVPGDFHLVHYGSRAIGGAGLLFTEMTCVSRDARITPGCAGLWNDVQEAAWKRIVD
FVHANSQAKFALQVGHAGRKGATRLMWDGMDRPLEQGGWDVVSASPLPYFPDSQVPRELDRVSMDAIKADFVAAAERGHR
CGFDMLELHCAHGYLLASFISPLTNKRTDQYGGSLENRLRFPLEVFAAMRAAWPAHKPMSVRISATDWAEGGITGDDAVR
IARAFGEAGVDLVDVSTGQTVREARPIYGRMFQTPFSDQVRNEAHVATMCVGNITTADQVNTILAAGRADLVALGRPHLV
DPAFTMKAAAWYGADMFCPPQYLPGKEQIFRNSVRERQDFEELKIKAKPKTRAELKAEAAKPLAAE
>Mature_786_residues
MEALMKIAIIGGGPAGLYAAILLKKQRPKADIAVYERNRADDTFGFGVVFSDATLDNFEKNDLPSYQRITQEFAYWDDIA
VHFRGTVHRVGGNGFCGCSRRTLLRILQERARELGVTLQFEVDLEEETQFADADLLILSDGINSRFRQKYVDHFQPEVDL
RANKFAWMGSTKPLDAFTFIFQETEWGPFIAHAYQYEAGHSTWIFETDPRTFEKAGLTGLDERQSADRMKDIFGWFLGDH
PLLINRSMWRNFPMIRNKRWVKDNMVLLGDAKSTAHFSIGSGTKLAMEDAIALADAMQRAPTIPAALDLYEHGRREEVEK
TQHAADVSLVWFEHVDRFWDFDPVQFAFGVMTRSKAITYDNLTLRAPDFVAEVDKSFARQVRSTGFDVDVDKPVAPMFQP
LKLREMTLANRAVLSPMCMYSAAEGVPGDFHLVHYGSRAIGGAGLLFTEMTCVSRDARITPGCAGLWNDVQEAAWKRIVD
FVHANSQAKFALQVGHAGRKGATRLMWDGMDRPLEQGGWDVVSASPLPYFPDSQVPRELDRVSMDAIKADFVAAAERGHR
CGFDMLELHCAHGYLLASFISPLTNKRTDQYGGSLENRLRFPLEVFAAMRAAWPAHKPMSVRISATDWAEGGITGDDAVR
IARAFGEAGVDLVDVSTGQTVREARPIYGRMFQTPFSDQVRNEAHVATMCVGNITTADQVNTILAAGRADLVALGRPHLV
DPAFTMKAAAWYGADMFCPPQYLPGKEQIFRNSVRERQDFEELKIKAKPKTRAELKAEAAKPLAAE

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=338, Percent_Identity=31.0650887573964, Blast_Score=139, Evalue=9e-34,
Organism=Escherichia coli, GI1789463, Length=369, Percent_Identity=26.0162601626016, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI72001454, Length=319, Percent_Identity=28.2131661442006, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17565138, Length=323, Percent_Identity=28.4829721362229, Blast_Score=118, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17559804, Length=324, Percent_Identity=29.0123456790123, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17564188, Length=324, Percent_Identity=28.3950617283951, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17559802, Length=316, Percent_Identity=28.4810126582279, Blast_Score=110, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17540738, Length=252, Percent_Identity=29.3650793650794, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17566914, Length=369, Percent_Identity=26.2872628726287, Blast_Score=91, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17566916, Length=285, Percent_Identity=28.7719298245614, Blast_Score=77, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6325086, Length=225, Percent_Identity=32.8888888888889, Blast_Score=103, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6321973, Length=257, Percent_Identity=31.9066147859922, Blast_Score=98, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 87968; Mature: 87968

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEALMKIAIIGGGPAGLYAAILLKKQRPKADIAVYERNRADDTFGFGVVFSDATLDNFEK
CCCEEEEEEECCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCC
NDLPSYQRITQEFAYWDDIAVHFRGTVHRVGGNGFCGCSRRTLLRILQERARELGVTLQF
CCCCHHHHHHHHHHHHHHEEEEECCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEE
EVDLEEETQFADADLLILSDGINSRFRQKYVDHFQPEVDLRANKFAWMGSTKPLDAFTFI
EECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHEEEE
FQETEWGPFIAHAYQYEAGHSTWIFETDPRTFEKAGLTGLDERQSADRMKDIFGWFLGDH
EECCCCCCHHHEEEEECCCCEEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
PLLINRSMWRNFPMIRNKRWVKDNMVLLGDAKSTAHFSIGSGTKLAMEDAIALADAMQRA
CEEEEHHHHHCCCCCCCCCEECCCEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHC
PTIPAALDLYEHGRREEVEKTQHAADVSLVWFEHVDRFWDFDPVQFAFGVMTRSKAITYD
CCCHHHHHHHHCCCHHHHHHHHHHHCEEEHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEC
NLTLRAPDFVAEVDKSFARQVRSTGFDVDVDKPVAPMFQPLKLREMTLANRAVLSPMCMY
CEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHH
SAAEGVPGDFHLVHYGSRAIGGAGLLFTEMTCVSRDARITPGCAGLWNDVQEAAWKRIVD
HHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
FVHANSQAKFALQVGHAGRKGATRLMWDGMDRPLEQGGWDVVSASPLPYFPDSQVPRELD
HHHCCCCCEEEEEECCCCCCCCCCCEECCCCCCHHCCCCCEEECCCCCCCCCCCCHHHHH
RVSMDAIKADFVAAAERGHRCGFDMLELHCAHGYLLASFISPLTNKRTDQYGGSLENRLR
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHC
FPLEVFAAMRAAWPAHKPMSVRISATDWAEGGITGDDAVRIARAFGEAGVDLVDVSTGQT
CHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCH
VREARPIYGRMFQTPFSDQVRNEAHVATMCVGNITTADQVNTILAAGRADLVALGRPHLV
HHHCCCHHHHHHCCCCHHHHCCCCEEEEEEECCCCCHHHHHHHHHCCCCCEEECCCCCCC
DPAFTMKAAAWYGADMFCPPQYLPGKEQIFRNSVRERQDFEELKIKAKPKTRAELKAEAA
CCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHCEEECCCCHHHHHHHHHC
KPLAAE
CCCCCC
>Mature Secondary Structure
MEALMKIAIIGGGPAGLYAAILLKKQRPKADIAVYERNRADDTFGFGVVFSDATLDNFEK
CCCEEEEEEECCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCC
NDLPSYQRITQEFAYWDDIAVHFRGTVHRVGGNGFCGCSRRTLLRILQERARELGVTLQF
CCCCHHHHHHHHHHHHHHEEEEECCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEE
EVDLEEETQFADADLLILSDGINSRFRQKYVDHFQPEVDLRANKFAWMGSTKPLDAFTFI
EECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHEEEE
FQETEWGPFIAHAYQYEAGHSTWIFETDPRTFEKAGLTGLDERQSADRMKDIFGWFLGDH
EECCCCCCHHHEEEEECCCCEEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
PLLINRSMWRNFPMIRNKRWVKDNMVLLGDAKSTAHFSIGSGTKLAMEDAIALADAMQRA
CEEEEHHHHHCCCCCCCCCEECCCEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHC
PTIPAALDLYEHGRREEVEKTQHAADVSLVWFEHVDRFWDFDPVQFAFGVMTRSKAITYD
CCCHHHHHHHHCCCHHHHHHHHHHHCEEEHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEC
NLTLRAPDFVAEVDKSFARQVRSTGFDVDVDKPVAPMFQPLKLREMTLANRAVLSPMCMY
CEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHH
SAAEGVPGDFHLVHYGSRAIGGAGLLFTEMTCVSRDARITPGCAGLWNDVQEAAWKRIVD
HHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
FVHANSQAKFALQVGHAGRKGATRLMWDGMDRPLEQGGWDVVSASPLPYFPDSQVPRELD
HHHCCCCCEEEEEECCCCCCCCCCCEECCCCCCHHCCCCCEEECCCCCCCCCCCCHHHHH
RVSMDAIKADFVAAAERGHRCGFDMLELHCAHGYLLASFISPLTNKRTDQYGGSLENRLR
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHC
FPLEVFAAMRAAWPAHKPMSVRISATDWAEGGITGDDAVRIARAFGEAGVDLVDVSTGQT
CHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCH
VREARPIYGRMFQTPFSDQVRNEAHVATMCVGNITTADQVNTILAAGRADLVALGRPHLV
HHHCCCHHHHHHCCCCHHHHCCCCEEEEEEECCCCCHHHHHHHHHCCCCCEEECCCCCCC
DPAFTMKAAAWYGADMFCPPQYLPGKEQIFRNSVRERQDFEELKIKAKPKTRAELKAEAA
CCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHCEEECCCCHHHHHHHHHC
KPLAAE
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]