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The map label for this gene is betA [C]

Identifier: 146339237

GI number: 146339237

Start: 2335697

End: 2337436

Strand: Reverse

Name: betA [C]

Synonym: BRADO2203

Alternate gene names: 146339237

Gene position: 2337436-2335697 (Counterclockwise)

Preceding gene: 146339240

Following gene: 146339236

Centisome position: 31.35

GC content: 65.23

Gene sequence:

>1740_bases
GTGATCATCTCGTATCCCGTCACGAGATCACATCCGGCGGGGCGACGCGCCTGCCTCGCAGGGTGCAAAGCTGAAGATAG
GCCGATGCTGATCGACTTCTCCAATCACAACGTGATCGAAGATTACGATGTCTGCGTGGTCGGAGCGGGTCCGGTCGGGA
TCGCGTTGGCGATCGCGTGCGAAGATCGCGGCCTGTCGGTCCTCGTAGTTGAATCGGGCGGCGAGCACCCGGACAGCTTC
ACGGCGCAGCTCAGCGCCGGGCACCTGGTAAATCCGCAGCACGCGCCTGCGGATATTGCGATATGCCGAGGGCTGGGCGG
TACCTCGCGGTGGTGGGGCGGCCGCTGTGTGCCGTTCGACGATGCCGACTTCGCCCCCGGTCCGGACCAGACCACGTCGG
TGTGGCCGCTCGATCATCCCGAGATCACCCGCTGGTATGGCGGGGCAGCCGACTTCTTCGGCATTGCACCTGACCGTTTC
GTCTCGCCGGCCGGCGGCTGGACAGCGTTCGGCGATACCCGTTGCGAGCAGCTCGAACGTTGGACGTCGCAGATCGACGC
TGGCGAGCGTCACTATGCGCGGCTGGCGAGTTCACCTCAGATCACGATGCTGCTTGGAGCCACCGTCACTGCGATCGAAC
TGGGAGATGGCGGACGGCGCGTCTCAGGTCTCTGTCTCGCGGACCGCAAGCGGCGCACGACCATCGCCCCGCCTTGCATT
GTTCTGGCCTGCGGCGGACTCGAGAGCACCAGGCTGCTGCTGCAGTTACGAACGGCCCATCCCGATGTCCTGGGCCTCAG
CTCCGGCGCGCTCGGTCGCGGTTACATGGGACATCTGTCCGGCAAGATCGCGGATATCGTGCTGGCGGATCCCGATGCCA
TTTCGGTGCACGACTTTTTCCTCGATGGCGGCGTCTTCGCCCGGCGCCGCCTGACATTGACGGCCGCAGCGCTCCGCCGT
CACGGGCTGCGCAATATCGCGTTTTGGGTCGACAACCCGGCTTTTCGCGTCGCGGATCATGGCAACGGCCTGCTGTCGCT
CGTGTGGCTCGCCCTTGCGATCCCGTGGCTCGGCCGCCGGCTGGTCGCCGAGGGCGTCAGGCTCAACCATGTCGGACGCA
GGCCCCACGCTTGGCTGCGGCACATCCTCAACGTTGTCAGCAATCCGTTCTCGACCATCCGGGATCTCGCTCAGATCTTG
ACGCATCGTTTGCTGGTGAAGCCGCGTAAGCCGGGCTTCATCTTGCACAACCGCAGCGGCCGCTATGCCCTGCACTACAT
GGCAGAACAGTCGGCACGTCCAGAGTCGCATGTCGACCTCTCCGATCGCAAGGATCCGCTCGGCCTGCCCTATCTGCGCG
TCAATCTGCGTTATCACGAAGACGACGCACAATCCGTGCTGCGGGCTCACGACGTGCTCGACCGCGATCTGCGTCAGGCT
GGGCTTGGCCGCCTCGACTATCATTGCGGCCGCGCCGAGCGTCTGGCCTCGATCCTCGACCAGGCCCACGACGGCTATCA
CCAACTTGGCACCGCCCCGATGGGCAGCAACCCGTCCACCAGCGTGGTCAATGCAGACTGCCGCGTGCATGGCATCGAGA
ACCTTTACGTCGCCTCGAGCGCAATCTTGCCGACCTCGGGTCAGGCCAACCCGACTTTCGTGACGGTTGCGCTGGCGCTG
CGCCTCGCCGCGCATCTGGCGTGCAGGATCCGGCGCAGCAGGCTCGGAGTCGCCGCATGA

Upstream 100 bases:

>100_bases
AACGCTGTATTACAGTTTGACGATATCATAAGCACGCCTGTCGCATTCCTGCATAACAGAAGAGATAATGGTCTCGCCGC
ATGATGCCTGACGAGTTGTC

Downstream 100 bases:

>100_bases
GGACGGTTCAAATCCCGCAACTCGATCGGCAGGTGTCGGCGCTGGGCTTCGGATGCGCGTCGCTGGGATCGCGCATCTCG
CCCGCAGCCGGAGGTCGCGC

Product: hypothetical protein

Products: Betaine Aldehyde; Reduced Acceptor. [C]

Alternate protein names: FAD Dependent Oxidoreductase; Glucose-Methanol-Choline Oxidoreductase; Oxidoreductase; Choline Dehydrogenase; NAD-Dependent Epimerase/Dehydratase; Choline Dehydrogenase-Like Flavoprotein; GMC Oxidoreductase Family; FAD-Dependent Pyridine Nucleotide-Disulfide Oxidoreductase; Dehydrogenase; Dehydrogenase Subunit I; Gluconate Dehydrogenase; Capsular Polysaccharide Biosynthesis Oxidoreductase

Number of amino acids: Translated: 579; Mature: 579

Protein sequence:

>579_residues
MIISYPVTRSHPAGRRACLAGCKAEDRPMLIDFSNHNVIEDYDVCVVGAGPVGIALAIACEDRGLSVLVVESGGEHPDSF
TAQLSAGHLVNPQHAPADIAICRGLGGTSRWWGGRCVPFDDADFAPGPDQTTSVWPLDHPEITRWYGGAADFFGIAPDRF
VSPAGGWTAFGDTRCEQLERWTSQIDAGERHYARLASSPQITMLLGATVTAIELGDGGRRVSGLCLADRKRRTTIAPPCI
VLACGGLESTRLLLQLRTAHPDVLGLSSGALGRGYMGHLSGKIADIVLADPDAISVHDFFLDGGVFARRRLTLTAAALRR
HGLRNIAFWVDNPAFRVADHGNGLLSLVWLALAIPWLGRRLVAEGVRLNHVGRRPHAWLRHILNVVSNPFSTIRDLAQIL
THRLLVKPRKPGFILHNRSGRYALHYMAEQSARPESHVDLSDRKDPLGLPYLRVNLRYHEDDAQSVLRAHDVLDRDLRQA
GLGRLDYHCGRAERLASILDQAHDGYHQLGTAPMGSNPSTSVVNADCRVHGIENLYVASSAILPTSGQANPTFVTVALAL
RLAAHLACRIRRSRLGVAA

Sequences:

>Translated_579_residues
MIISYPVTRSHPAGRRACLAGCKAEDRPMLIDFSNHNVIEDYDVCVVGAGPVGIALAIACEDRGLSVLVVESGGEHPDSF
TAQLSAGHLVNPQHAPADIAICRGLGGTSRWWGGRCVPFDDADFAPGPDQTTSVWPLDHPEITRWYGGAADFFGIAPDRF
VSPAGGWTAFGDTRCEQLERWTSQIDAGERHYARLASSPQITMLLGATVTAIELGDGGRRVSGLCLADRKRRTTIAPPCI
VLACGGLESTRLLLQLRTAHPDVLGLSSGALGRGYMGHLSGKIADIVLADPDAISVHDFFLDGGVFARRRLTLTAAALRR
HGLRNIAFWVDNPAFRVADHGNGLLSLVWLALAIPWLGRRLVAEGVRLNHVGRRPHAWLRHILNVVSNPFSTIRDLAQIL
THRLLVKPRKPGFILHNRSGRYALHYMAEQSARPESHVDLSDRKDPLGLPYLRVNLRYHEDDAQSVLRAHDVLDRDLRQA
GLGRLDYHCGRAERLASILDQAHDGYHQLGTAPMGSNPSTSVVNADCRVHGIENLYVASSAILPTSGQANPTFVTVALAL
RLAAHLACRIRRSRLGVAA
>Mature_579_residues
MIISYPVTRSHPAGRRACLAGCKAEDRPMLIDFSNHNVIEDYDVCVVGAGPVGIALAIACEDRGLSVLVVESGGEHPDSF
TAQLSAGHLVNPQHAPADIAICRGLGGTSRWWGGRCVPFDDADFAPGPDQTTSVWPLDHPEITRWYGGAADFFGIAPDRF
VSPAGGWTAFGDTRCEQLERWTSQIDAGERHYARLASSPQITMLLGATVTAIELGDGGRRVSGLCLADRKRRTTIAPPCI
VLACGGLESTRLLLQLRTAHPDVLGLSSGALGRGYMGHLSGKIADIVLADPDAISVHDFFLDGGVFARRRLTLTAAALRR
HGLRNIAFWVDNPAFRVADHGNGLLSLVWLALAIPWLGRRLVAEGVRLNHVGRRPHAWLRHILNVVSNPFSTIRDLAQIL
THRLLVKPRKPGFILHNRSGRYALHYMAEQSARPESHVDLSDRKDPLGLPYLRVNLRYHEDDAQSVLRAHDVLDRDLRQA
GLGRLDYHCGRAERLASILDQAHDGYHQLGTAPMGSNPSTSVVNADCRVHGIENLYVASSAILPTSGQANPTFVTVALAL
RLAAHLACRIRRSRLGVAA

Specific function: Can Catalyze The Oxidation Of Choline To Betaine Aldehyde And Betaine Aldehyde To Glycine Betaine At The Same Rate. [C]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.1.99.1 [C]

Molecular weight: Translated: 62933; Mature: 62933

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIISYPVTRSHPAGRRACLAGCKAEDRPMLIDFSNHNVIEDYDVCVVGAGPVGIALAIAC
CEEECCCCCCCCCCCHHHHHCCCCCCCCEEEEECCCCCEECCCEEEECCCCCCEEEEEEE
EDRGLSVLVVESGGEHPDSFTAQLSAGHLVNPQHAPADIAICRGLGGTSRWWGGRCVPFD
CCCCCEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCEECCCCCCCCCCCCEECCCC
DADFAPGPDQTTSVWPLDHPEITRWYGGAADFFGIAPDRFVSPAGGWTAFGDTRCEQLER
CCCCCCCCCCCCEECCCCCCCHHHHCCCCHHHCCCCCHHHCCCCCCCCCCCCHHHHHHHH
WTSQIDAGERHYARLASSPQITMLLGATVTAIELGDGGRRVSGLCLADRKRRTTIAPPCI
HHHHCCCCHHHHHHHCCCCCEEEEECCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCEE
VLACGGLESTRLLLQLRTAHPDVLGLSSGALGRGYMGHLSGKIADIVLADPDAISVHDFF
EEEECCCCHHEEEEEEECCCCCEEECCCCCCCCCCHHHCCCCEEEEEEECCCCEEEEEEE
LDGGVFARRRLTLTAAALRRHGLRNIAFWVDNPAFRVADHGNGLLSLVWLALAIPWLGRR
ECCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHH
LVAEGVRLNHVGRRPHAWLRHILNVVSNPFSTIRDLAQILTHRLLVKPRKPGFILHNRSG
HHHCCCEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
RYALHYMAEQSARPESHVDLSDRKDPLGLPYLRVNLRYHEDDAQSVLRAHDVLDRDLRQA
CEEEEEEHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHH
GLGRLDYHCGRAERLASILDQAHDGYHQLGTAPMGSNPSTSVVNADCRVHGIENLYVASS
CCCCHHHCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCEEECCEEEECCCEEEEECC
AILPTSGQANPTFVTVALALRLAAHLACRIRRSRLGVAA
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIISYPVTRSHPAGRRACLAGCKAEDRPMLIDFSNHNVIEDYDVCVVGAGPVGIALAIAC
CEEECCCCCCCCCCCHHHHHCCCCCCCCEEEEECCCCCEECCCEEEECCCCCCEEEEEEE
EDRGLSVLVVESGGEHPDSFTAQLSAGHLVNPQHAPADIAICRGLGGTSRWWGGRCVPFD
CCCCCEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCEECCCCCCCCCCCCEECCCC
DADFAPGPDQTTSVWPLDHPEITRWYGGAADFFGIAPDRFVSPAGGWTAFGDTRCEQLER
CCCCCCCCCCCCEECCCCCCCHHHHCCCCHHHCCCCCHHHCCCCCCCCCCCCHHHHHHHH
WTSQIDAGERHYARLASSPQITMLLGATVTAIELGDGGRRVSGLCLADRKRRTTIAPPCI
HHHHCCCCHHHHHHHCCCCCEEEEECCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCEE
VLACGGLESTRLLLQLRTAHPDVLGLSSGALGRGYMGHLSGKIADIVLADPDAISVHDFF
EEEECCCCHHEEEEEEECCCCCEEECCCCCCCCCCHHHCCCCEEEEEEECCCCEEEEEEE
LDGGVFARRRLTLTAAALRRHGLRNIAFWVDNPAFRVADHGNGLLSLVWLALAIPWLGRR
ECCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHH
LVAEGVRLNHVGRRPHAWLRHILNVVSNPFSTIRDLAQILTHRLLVKPRKPGFILHNRSG
HHHCCCEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
RYALHYMAEQSARPESHVDLSDRKDPLGLPYLRVNLRYHEDDAQSVLRAHDVLDRDLRQA
CEEEEEEHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHH
GLGRLDYHCGRAERLASILDQAHDGYHQLGTAPMGSNPSTSVVNADCRVHGIENLYVASS
CCCCHHHCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCEEECCEEEECCCEEEEECC
AILPTSGQANPTFVTVALALRLAAHLACRIRRSRLGVAA
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Coenzyme Q [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 7 {choline}} 1.1 {phenazine}} [C]

Substrates: Choline; Acceptor [C]

Specific reaction: Choline + Acceptor = Betaine Aldehyde + Reduced Acceptor. [C]

General reaction: Redox reaction [C]

Inhibitor: 2-Dimethylaminoethanol; Betaine aldehyde; Monoethanolamine; Semicarbazide [C]

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA