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The map label for this gene is 146339203

Identifier: 146339203

GI number: 146339203

Start: 2299483

End: 2300412

Strand: Reverse

Name: 146339203

Synonym: BRADO2165

Alternate gene names: NA

Gene position: 2300412-2299483 (Counterclockwise)

Preceding gene: 146339204

Following gene: 146339202

Centisome position: 30.85

GC content: 66.34

Gene sequence:

>930_bases
ATGTCGACGCTGTATCTCTCTCATGAAGCCTGCCTCGATCACGCCACCCCGTCCGGACATCCCGAGCGCGCCGACCGGCT
GCGTGCCGTCGAGGAGGCGCTGACCGAGGAGCGCTTTGCCCTGCTCGATCGCGACGAGGCGCCGGAGGCCGACATCGAGC
TGCCCCTGCTCTGCCACAACGAGCATTACGTCACCGAGCTGCGCCAGATGGCTCCGACTTCAGGCATCATCTATCTCGAC
GGCGACACCTCGATGTCTCCGGGCACCTGGGAAGCGGTCATGCGCGGCGTCGGCGGCGCGGTGGCGGCCACCGAGTCCGT
GATGTCCGGCAAGCACAGGAACGCCTTCGTTGCCGTGCGCCCGCCCGGGCATCACGCCGAGATCGCCAAGCCGATGGGGT
TCTGCTTCTTCGACAATGTTGCGATCGCCGCGCGCTACGCCCAGCGCACCTTCGGGATCGAGCGCGCCGCGATCATTGAT
TTCGACGTCCACCACGGCAACGGCACCCAGGATATCTTCTGGGCCGACAAGAGCGTGATGTACTGCTCGACCCACCAGAT
GCCGCTGTTCCCGGGCACCGGGGCGCGCAGCGAGCGTGGCGAGCACGACACCATCGTCAACGCGCCGCTCGCCTCCGAGG
ATGGCAGCCTGGAGTTCCGCTCGGCCTTCGAGAATCTGATCCTGCCGCAACTGACCAAGTTCAGCCCGGAGCTCGTGATC
ATCTCGGCCGGCTTCGACGCCCACTACCGCGACCCGCTGGCATCGCTGAACCTGCGCGCCGAAGACTTCGGCTGGGTCAC
GCGCAAACTGATGGAGCTTGCCGACAAGACCGCGGGCGGGCGTGTCGTCTCGGTGCTGGAAGGCGGCTATGATCTTCAGG
GCCTTAAGGAATCCGTCTCGGCCCATGTCGCGGCGCTGACCGGGGCGTAA

Upstream 100 bases:

>100_bases
CGGGAAAGCCAGTCAGATCCTCCGTCATGGCTCTTTCCGAGGCTGCGTTCAGCGCATAGATTGGGCACTCCCGCAACGCG
CGAGTGGCAGGGCCTGTTGA

Downstream 100 bases:

>100_bases
TCCCCAGGTTCCGGGCAATCCAACCTGGCGGGGCCTGACAGAGCTCCAGCCGGAGTGTAAAAGCACGGCCCCGGAGTTGA
GTATCTGCAGGGAACCCGTA

Product: putative deacetylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSTLYLSHEACLDHATPSGHPERADRLRAVEEALTEERFALLDRDEAPEADIELPLLCHNEHYVTELRQMAPTSGIIYLD
GDTSMSPGTWEAVMRGVGGAVAATESVMSGKHRNAFVAVRPPGHHAEIAKPMGFCFFDNVAIAARYAQRTFGIERAAIID
FDVHHGNGTQDIFWADKSVMYCSTHQMPLFPGTGARSERGEHDTIVNAPLASEDGSLEFRSAFENLILPQLTKFSPELVI
ISAGFDAHYRDPLASLNLRAEDFGWVTRKLMELADKTAGGRVVSVLEGGYDLQGLKESVSAHVAALTGA

Sequences:

>Translated_309_residues
MSTLYLSHEACLDHATPSGHPERADRLRAVEEALTEERFALLDRDEAPEADIELPLLCHNEHYVTELRQMAPTSGIIYLD
GDTSMSPGTWEAVMRGVGGAVAATESVMSGKHRNAFVAVRPPGHHAEIAKPMGFCFFDNVAIAARYAQRTFGIERAAIID
FDVHHGNGTQDIFWADKSVMYCSTHQMPLFPGTGARSERGEHDTIVNAPLASEDGSLEFRSAFENLILPQLTKFSPELVI
ISAGFDAHYRDPLASLNLRAEDFGWVTRKLMELADKTAGGRVVSVLEGGYDLQGLKESVSAHVAALTGA
>Mature_308_residues
STLYLSHEACLDHATPSGHPERADRLRAVEEALTEERFALLDRDEAPEADIELPLLCHNEHYVTELRQMAPTSGIIYLDG
DTSMSPGTWEAVMRGVGGAVAATESVMSGKHRNAFVAVRPPGHHAEIAKPMGFCFFDNVAIAARYAQRTFGIERAAIIDF
DVHHGNGTQDIFWADKSVMYCSTHQMPLFPGTGARSERGEHDTIVNAPLASEDGSLEFRSAFENLILPQLTKFSPELVII
SAGFDAHYRDPLASLNLRAEDFGWVTRKLMELADKTAGGRVVSVLEGGYDLQGLKESVSAHVAALTGA

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI30795204, Length=342, Percent_Identity=36.5497076023392, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI30795202, Length=342, Percent_Identity=36.5497076023392, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI17158039, Length=342, Percent_Identity=36.5497076023392, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI153085395, Length=224, Percent_Identity=42.4107142857143, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI62750347, Length=332, Percent_Identity=33.7349397590361, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI62750349, Length=332, Percent_Identity=34.3373493975904, Blast_Score=165, Evalue=4e-41,
Organism=Homo sapiens, GI13128864, Length=302, Percent_Identity=38.0794701986755, Blast_Score=164, Evalue=8e-41,
Organism=Homo sapiens, GI148539870, Length=214, Percent_Identity=43.9252336448598, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI169234807, Length=214, Percent_Identity=43.9252336448598, Blast_Score=158, Evalue=5e-39,
Organism=Homo sapiens, GI20070354, Length=310, Percent_Identity=36.1290322580645, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI226529806, Length=310, Percent_Identity=32.5806451612903, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI8923769, Length=289, Percent_Identity=24.9134948096886, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI13128860, Length=263, Percent_Identity=26.2357414448669, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI293336691, Length=263, Percent_Identity=25.4752851711027, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI13128862, Length=262, Percent_Identity=23.6641221374046, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI217272877, Length=289, Percent_Identity=28.0276816608997, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI209862883, Length=282, Percent_Identity=27.6595744680851, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI262073088, Length=168, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17540334, Length=308, Percent_Identity=36.6883116883117, Blast_Score=177, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI193206283, Length=308, Percent_Identity=36.6883116883117, Blast_Score=177, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI17540332, Length=308, Percent_Identity=36.6883116883117, Blast_Score=177, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI193209491, Length=333, Percent_Identity=33.9339339339339, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI25154020, Length=315, Percent_Identity=29.8412698412698, Blast_Score=134, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI25154022, Length=317, Percent_Identity=29.6529968454259, Blast_Score=130, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17537347, Length=316, Percent_Identity=31.6455696202532, Blast_Score=127, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17534739, Length=309, Percent_Identity=23.9482200647249, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17508561, Length=256, Percent_Identity=24.21875, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17561978, Length=224, Percent_Identity=25.4464285714286, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324307, Length=223, Percent_Identity=37.219730941704, Blast_Score=145, Evalue=6e-36,
Organism=Saccharomyces cerevisiae, GI6325141, Length=288, Percent_Identity=28.125, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6323999, Length=301, Percent_Identity=25.5813953488372, Blast_Score=86, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6321244, Length=289, Percent_Identity=24.5674740484429, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6325325, Length=128, Percent_Identity=29.6875, Blast_Score=69, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24642146, Length=315, Percent_Identity=35.2380952380952, Blast_Score=178, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24642142, Length=315, Percent_Identity=35.2380952380952, Blast_Score=178, Evalue=4e-45,
Organism=Drosophila melanogaster, GI281360899, Length=315, Percent_Identity=35.2380952380952, Blast_Score=178, Evalue=5e-45,
Organism=Drosophila melanogaster, GI24642144, Length=315, Percent_Identity=35.2380952380952, Blast_Score=177, Evalue=5e-45,
Organism=Drosophila melanogaster, GI24641720, Length=343, Percent_Identity=34.1107871720117, Blast_Score=157, Evalue=7e-39,
Organism=Drosophila melanogaster, GI281360799, Length=343, Percent_Identity=34.1107871720117, Blast_Score=157, Evalue=7e-39,
Organism=Drosophila melanogaster, GI281360801, Length=343, Percent_Identity=34.1107871720117, Blast_Score=157, Evalue=9e-39,
Organism=Drosophila melanogaster, GI24657891, Length=284, Percent_Identity=28.169014084507, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24644244, Length=299, Percent_Identity=25.0836120401338, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286
- InterPro:   IPR003084 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 33707; Mature: 33576

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLYLSHEACLDHATPSGHPERADRLRAVEEALTEERFALLDRDEAPEADIELPLLCHN
CCEEEECHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECC
EHYVTELRQMAPTSGIIYLDGDTSMSPGTWEAVMRGVGGAVAATESVMSGKHRNAFVAVR
CHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEC
PPGHHAEIAKPMGFCFFDNVAIAARYAQRTFGIERAAIIDFDVHHGNGTQDIFWADKSVM
CCCCCHHHHCCCCHHHCCCHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCEEEECCCEEE
YCSTHQMPLFPGTGARSERGEHDTIVNAPLASEDGSLEFRSAFENLILPQLTKFSPELVI
EEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEE
ISAGFDAHYRDPLASLNLRAEDFGWVTRKLMELADKTAGGRVVSVLEGGYDLQGLKESVS
EECCCCCHHCCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHH
AHVAALTGA
HHHHEECCC
>Mature Secondary Structure 
STLYLSHEACLDHATPSGHPERADRLRAVEEALTEERFALLDRDEAPEADIELPLLCHN
CEEEECHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECC
EHYVTELRQMAPTSGIIYLDGDTSMSPGTWEAVMRGVGGAVAATESVMSGKHRNAFVAVR
CHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEC
PPGHHAEIAKPMGFCFFDNVAIAARYAQRTFGIERAAIIDFDVHHGNGTQDIFWADKSVM
CCCCCHHHHCCCCHHHCCCHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCEEEECCCEEE
YCSTHQMPLFPGTGARSERGEHDTIVNAPLASEDGSLEFRSAFENLILPQLTKFSPELVI
EEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEE
ISAGFDAHYRDPLASLNLRAEDFGWVTRKLMELADKTAGGRVVSVLEGGYDLQGLKESVS
EECCCCCHHCCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHH
AHVAALTGA
HHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]