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The map label for this gene is hflB [C]

Identifier: 146338903

GI number: 146338903

Start: 1969221

End: 1970903

Strand: Direct

Name: hflB [C]

Synonym: BRADO1843

Alternate gene names: 146338903

Gene position: 1969221-1970903 (Clockwise)

Preceding gene: 146338902

Following gene: 146338905

Centisome position: 26.41

GC content: 65.48

Gene sequence:

>1683_bases
TTGGCGGCCGCTTTCCCGCATCTGACTTCTCTCAAGGAGCAGCTGCGCTTCGGCGACAAGGTCGAGCTCAATCTCGCGCA
GCTGGCGACGGCCGAGCTCGACATCCTGCGTGCTTACTATCAGAACGCCGGTCCTGAATGGCATGCGCGGGCCGCGCACA
TCGCGACGCTGCAGCGCGCCTTCAGCGATTCCGGCACGCGCTTCTCCGAGCATGAGCTCGAGCAGGTGCTCCCGGCGATC
GCGCGCTACCTCATCTCGGGTGCGATCCGCGGCTGGATGTTCACCGCCAATGTTGCCAGCCGGCCGCTGCCTTATGTCGT
GACGCGGCTCGACTACACCGCGCCGTCCAACGACGAGGCCGGACGTGTCTTCATCGAGCTCAAGGCCAATGCCAAGGGCG
CCATCACGACATCGACCTTGCGGATCTCCGTCGGCGACATCGTCGGCCGCACCGTGGCCGAGATCTTCGCCGCCAAGGGC
TTTCTCAAGGAGACTCCCGAGCTGATCGCCGCCTATGACGAGACCGCGGAGCGCTACTTCGCCTGGCGCGGGCGCTATGG
CGCGCAGTTCTCCGGGCGCGGCATCGGCTTCTTCGCCGATGATCCGAACTCGTCGCACCGCGACACGGACTGGTCGCGCA
AGGACGTCATCGTGCTGTCCTCCGGCGGCGGCAGCGCGCGGCTCGTCAACGACGAGGGCATCCTGACCGAGCGTGCCCTG
ACGTTGGAAGTCACCGGCGACATTCTCGGGCAGTACCTGCGCAAGGCCGCCAAGAGCAATCTCTACGATGCCGAGCAGGA
GGTCGAGGACTCCAAGGCGGCGATCCCGACGGGCGTGTTCTGCCGCGTTCCCGTGCATCCGTATATGCTCATGTTCCATC
TCGACCTGCACCATTACGTCTGGGTGCACGCCGACGACATGACGCCCTACGCCTATCAGCCGGAGTTGAAGCAGAAGCTG
GTCCTGCCGGAGGAGCAGACCGACCTGATCGACATCCTCACCGCCGAGATGGACCTGCTGATGGACGACATCGTCGCCGG
CAAGTCGGGCGGCACGACGGTGCTGTGCGCGGGCCCGCCCGGCGTCGGCAAGACACTGACCGCGGAGGTCTATGCCGAGA
TCATCGGCCGTCCACTCTACCGCGTGCACTCCGGCCAACTCGGGCTGAACGTGGCGGCGATGGAAAGCGCGCTGAAGGAC
GCGCTGACGCGCGCGCAGCGCTGGGGCGCCGTCATGCTGATCGACGAGGCCGACGTCTATATCAAGCGGCGCGAGGATGA
CATGACGATGAACGCCGTCGTCGGGGTCTTCCTGCGCGTGCTCGAATATTTCAACGGCCTGTTGTTCCTCACCACCAACC
GCATCGACGACATCGATGAAGCAATCGTGTCGCGCTGCATCGCGCTGATCAAGTTCCAGGCGCCGGATGCCGACGCGCGC
GGCCGGATCTGGCGGGTGATGTGCGATCAGTTCGGATTGAAGGTCGAGGCGGCGGTGATCGCACAGCTGGTGGAAATTTT
TCCGGCCGCCTCGGGCCGCGACATCAAGGGCCTCGCCAAGCTGGTCGCAAAATACTGCCACCACAAGAGCGTGCGCCCGA
CCATCGCCGTCTTCCGCCGCTGCGCCATCTTCCGCGGCCTCGACCTCGGCGATCACGAGTCGCTGCCGGAGGCGGCGGAG
TAG

Upstream 100 bases:

>100_bases
GGCGAGGCGGCCCGTCAGCCGACCAGCGTGTCGTCGTGACAGCGAAGCAAATGAGCGCGCTCCGATGAAGCTGCAGATTG
ATCGTCCGGCGATCGAAGCG

Downstream 100 bases:

>100_bases
ATCCGCTAACAACTGTTGGCCATGCCGAGCGTCGCCGGACTGTATCCTTCTTCGCGCAGGACCCGCTGCACCACGGGCCG
CGCCAGCATCCGGCGGTAGT

Product: ATPase

Products: NA

Alternate protein names: AAA ATPase Central Domain Protein; ATPase; ATPase AAA Family Protein; AAA Family ATPase; AAA ATPase; AAA ATPase Central Domain-Containing Protein; AAA ATPase Family Protein; AAA ATPase Central Region; ATP-Dependent Zn Proteases; ATPase AAA Family; AAA-Family ATPase Protein; ATPases Of AAA+ Class; ATPase Of AAA+ Class; ATPase AAA Superfamily; ATPase Aaa Family; AAA+ Family ATPase; Elongation Factor P; ATPase Protein

Number of amino acids: Translated: 560; Mature: 559

Protein sequence:

>560_residues
MAAAFPHLTSLKEQLRFGDKVELNLAQLATAELDILRAYYQNAGPEWHARAAHIATLQRAFSDSGTRFSEHELEQVLPAI
ARYLISGAIRGWMFTANVASRPLPYVVTRLDYTAPSNDEAGRVFIELKANAKGAITTSTLRISVGDIVGRTVAEIFAAKG
FLKETPELIAAYDETAERYFAWRGRYGAQFSGRGIGFFADDPNSSHRDTDWSRKDVIVLSSGGGSARLVNDEGILTERAL
TLEVTGDILGQYLRKAAKSNLYDAEQEVEDSKAAIPTGVFCRVPVHPYMLMFHLDLHHYVWVHADDMTPYAYQPELKQKL
VLPEEQTDLIDILTAEMDLLMDDIVAGKSGGTTVLCAGPPGVGKTLTAEVYAEIIGRPLYRVHSGQLGLNVAAMESALKD
ALTRAQRWGAVMLIDEADVYIKRREDDMTMNAVVGVFLRVLEYFNGLLFLTTNRIDDIDEAIVSRCIALIKFQAPDADAR
GRIWRVMCDQFGLKVEAAVIAQLVEIFPAASGRDIKGLAKLVAKYCHHKSVRPTIAVFRRCAIFRGLDLGDHESLPEAAE

Sequences:

>Translated_560_residues
MAAAFPHLTSLKEQLRFGDKVELNLAQLATAELDILRAYYQNAGPEWHARAAHIATLQRAFSDSGTRFSEHELEQVLPAI
ARYLISGAIRGWMFTANVASRPLPYVVTRLDYTAPSNDEAGRVFIELKANAKGAITTSTLRISVGDIVGRTVAEIFAAKG
FLKETPELIAAYDETAERYFAWRGRYGAQFSGRGIGFFADDPNSSHRDTDWSRKDVIVLSSGGGSARLVNDEGILTERAL
TLEVTGDILGQYLRKAAKSNLYDAEQEVEDSKAAIPTGVFCRVPVHPYMLMFHLDLHHYVWVHADDMTPYAYQPELKQKL
VLPEEQTDLIDILTAEMDLLMDDIVAGKSGGTTVLCAGPPGVGKTLTAEVYAEIIGRPLYRVHSGQLGLNVAAMESALKD
ALTRAQRWGAVMLIDEADVYIKRREDDMTMNAVVGVFLRVLEYFNGLLFLTTNRIDDIDEAIVSRCIALIKFQAPDADAR
GRIWRVMCDQFGLKVEAAVIAQLVEIFPAASGRDIKGLAKLVAKYCHHKSVRPTIAVFRRCAIFRGLDLGDHESLPEAAE
>Mature_559_residues
AAAFPHLTSLKEQLRFGDKVELNLAQLATAELDILRAYYQNAGPEWHARAAHIATLQRAFSDSGTRFSEHELEQVLPAIA
RYLISGAIRGWMFTANVASRPLPYVVTRLDYTAPSNDEAGRVFIELKANAKGAITTSTLRISVGDIVGRTVAEIFAAKGF
LKETPELIAAYDETAERYFAWRGRYGAQFSGRGIGFFADDPNSSHRDTDWSRKDVIVLSSGGGSARLVNDEGILTERALT
LEVTGDILGQYLRKAAKSNLYDAEQEVEDSKAAIPTGVFCRVPVHPYMLMFHLDLHHYVWVHADDMTPYAYQPELKQKLV
LPEEQTDLIDILTAEMDLLMDDIVAGKSGGTTVLCAGPPGVGKTLTAEVYAEIIGRPLYRVHSGQLGLNVAAMESALKDA
LTRAQRWGAVMLIDEADVYIKRREDDMTMNAVVGVFLRVLEYFNGLLFLTTNRIDDIDEAIVSRCIALIKFQAPDADARG
RIWRVMCDQFGLKVEAAVIAQLVEIFPAASGRDIKGLAKLVAKYCHHKSVRPTIAVFRRCAIFRGLDLGDHESLPEAAE

Specific function: Seems To Act As An ATP-Dependent Zinc Metallopeptidase. Involved In The Degradation Of Sigma-32. Degrades Carboxy- Terminal-Tagged Cytoplasmic Proteins. These Proteins Are Tagged With An 11-Amino-Acid Nonpolar Destabilizing Tail VIa A Mechanism Involving

COG id: COG0464

COG function: function code O; ATPases of the AAA+ class

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.4.24.- [C]

Molecular weight: Translated: 61895; Mature: 61764

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAAFPHLTSLKEQLRFGDKVELNLAQLATAELDILRAYYQNAGPEWHARAAHIATLQRA
CCCCCCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
FSDSGTRFSEHELEQVLPAIARYLISGAIRGWMFTANVASRPLPYVVTRLDYTAPSNDEA
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCEEEEEECCCCCCCCC
GRVFIELKANAKGAITTSTLRISVGDIVGRTVAEIFAAKGFLKETPELIAAYDETAERYF
CEEEEEEECCCCCCEEEEEEEEEHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHH
AWRGRYGAQFSGRGIGFFADDPNSSHRDTDWSRKDVIVLSSGGGSARLVNDEGILTERAL
HHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCEEEEEE
TLEVTGDILGQYLRKAAKSNLYDAEQEVEDSKAAIPTGVFCRVPVHPYMLMFHLDLHHYV
EEEECHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEECCCCCEEEEEEEEHHEEE
WVHADDMTPYAYQPELKQKLVLPEEQTDLIDILTAEMDLLMDDIVAGKSGGTTVLCAGPP
EEEECCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
GVGKTLTAEVYAEIIGRPLYRVHSGQLGLNVAAMESALKDALTRAQRWGAVMLIDEADVY
CCCCHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCEE
IKRREDDMTMNAVVGVFLRVLEYFNGLLFLTTNRIDDIDEAIVSRCIALIKFQAPDADAR
EEECCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHEECCCCCCCC
GRIWRVMCDQFGLKVEAAVIAQLVEIFPAASGRDIKGLAKLVAKYCHHKSVRPTIAVFRR
CHHHHHHHHHHCCEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
CAIFRGLDLGDHESLPEAAE
HHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AAAFPHLTSLKEQLRFGDKVELNLAQLATAELDILRAYYQNAGPEWHARAAHIATLQRA
CCCCCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
FSDSGTRFSEHELEQVLPAIARYLISGAIRGWMFTANVASRPLPYVVTRLDYTAPSNDEA
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCEEEEEECCCCCCCCC
GRVFIELKANAKGAITTSTLRISVGDIVGRTVAEIFAAKGFLKETPELIAAYDETAERYF
CEEEEEEECCCCCCEEEEEEEEEHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHH
AWRGRYGAQFSGRGIGFFADDPNSSHRDTDWSRKDVIVLSSGGGSARLVNDEGILTERAL
HHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCEEEEEE
TLEVTGDILGQYLRKAAKSNLYDAEQEVEDSKAAIPTGVFCRVPVHPYMLMFHLDLHHYV
EEEECHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEECCCCCEEEEEEEEHHEEE
WVHADDMTPYAYQPELKQKLVLPEEQTDLIDILTAEMDLLMDDIVAGKSGGTTVLCAGPP
EEEECCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
GVGKTLTAEVYAEIIGRPLYRVHSGQLGLNVAAMESALKDALTRAQRWGAVMLIDEADVY
CCCCHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCEE
IKRREDDMTMNAVVGVFLRVLEYFNGLLFLTTNRIDDIDEAIVSRCIALIKFQAPDADAR
EEECCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHEECCCCCCCC
GRIWRVMCDQFGLKVEAAVIAQLVEIFPAASGRDIKGLAKLVAKYCHHKSVRPTIAVFRR
CHHHHHHHHHHCCEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
CAIFRGLDLGDHESLPEAAE
HHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA