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The map label for this gene is cheA [H]

Identifier: 146338883

GI number: 146338883

Start: 1947806

End: 1949860

Strand: Direct

Name: cheA [H]

Synonym: BRADO1822

Alternate gene names: 146338883

Gene position: 1947806-1949860 (Clockwise)

Preceding gene: 146338882

Following gene: 146338884

Centisome position: 26.12

GC content: 65.35

Gene sequence:

>2055_bases
ATGTCCGTAACGTCAGAGCAAGAATCCTATCCGGTCGCGCAATTCCGCAAAACCTATTTCGAGGAATGCGCGGAGCTGCT
TGACGCGTTGCAGTCGAACCTCGAACTTCTGTCGTCGGGACAGGAGGACGACGAGACGCTGCACGCGATCTTCCGTTCGG
TCCATTCCATCAAGGGCGGCGCCGGCGCTTTCGGCTGCACCGATCTGGTGGCGTTCTCGCACACCTTCGAGAGCCTGCTC
GACGCGCTGCGCGACCACAAGATCGCGACCACCAACGAGGTCAAGCAGCTGCTGCTCCGCGCCAGCGATGCGCTGGCCGA
CATCGTGAATGCCGCGCGGCTCGAGCAGCAGCTGCCTGCAGACTTTGCTGCCGATATTCGCTCGGCCATGCAGGACGTGC
TGCAGGGCGCCGGTCACCCGGTCGAGACGAAGCCTGCGCCGTCCGCTTCGGACGCGAAGCTGCTCAGCGAGCAAACCTAC
CGCATCAGGTTTCGCCCCCACACGGAGATGCTGAGAAAGGCGAATGAGCCGCTGCTGCTGATCCGCCAGCTTCGCAAGCT
CGGCACGCTCACGACCGAGGTCGATTTCTCGGCGCTGCCGGCGCTCGAGGCGTTGGATCCCGAGGCGGCCTATTTCAACT
GGACGTTCACGCTGGAAACCGCCGTGCCGCGCGGCAGCATTCAGGACGTGTTCGAATTCGTCGAGGATGATTGCGATCTT
CAGATCGACCTGTTGCAGACGGCTGTGCCGACCGCCGAAGTGGCCGTCGGAGAGTCCAGCAGCGCGACCGCTCCGGCGGC
AGCTGCAGTGTCGCTCGCACAGTCGATCCGCGTCGACGTCGACAAGGTCGACCGTCTTGTGAATCTCGTCGGCGAGCTCG
TGATCAGCCAGGCGATGCTGACTGAGCAGGGCATGTCTCTGCCGGCCGACAAATATCCGCAGCTCATCCAGGGCATCGAG
GCGCTGGCGCAGAGCGCGCGCGAGTTGCAGGAAAGCGTGATGGCGATCCGCGCCCAGCCGGTCAAATCGGTGTTCGCGCG
GATGCCGCGCATCGTCCGCGAGCTTGCGGCCGTGCTCGGCAAGGAGGTGCGCATCGTCACCTCCGGCGAGATGACCGAAA
TCGACAAGACGGTGATCGAGCAGCTCAACGATCCCCTGACGCATATGATCCGCAACGCGCTCGACCACGGCATCGAGCCG
CCGGCCGAGCGGCTTGCCGCGGGCAAGCCGCGACAGGGAACGATCAATCTGTCGGCGGCCCAGCGCAGCGGCCGCATCGT
CATCGAGGTCTCGGACGACGGCCGCGGCATCAACCGCGAACGAATCCTGGAGAAGGCGCGCGCGCGGGGCTTGGTGCCGC
CGGGTGCCAACCTCACCGACGACGAGATCGACAACCTGATCTTCATGCCGGCGTTCTCCACCGCCGAGGTGATCTCGAAC
ATTTCCGGACGCGGCGTCGGCATGGACGTCGTGAAGCGCAACGTGCAGGCGCTCGGCGGCCGGATCTCGGTCCGCTCGCG
CTTCGGCCACGGCTCGTCATTCACGCTCTCGCTGCCGCTGACGCTGGCCGTGGTCGACGGCATGGTCGTGTCGGTCGGAC
GCGAGACGTTCATCATTCCCCTGGTCGCGATCGTCGAGAACCTCCGTCCGCAGTCAGCCGACATCCATCCGGTGGTCGGA
CGGGGGCACGTCCTGGCGCTGCGCGGGGAGTACCTGCCGCTGGTCTACCTGCATCGCGTGTTCGCGATCAGCGATGCGAT
CAGCGATCCCTGCCGCGGCATCGTCATCATCGTACAGAGCGAGAGCGCCGGGCGCGTCGGCATCGTCGTTGACGAACTGC
TCGGTCAGCAGCAGGTCGTCGTCAAGAGTCTCGAGGCCAATTACGAGCCGGTCGAGGGCATCAGCGGCGCGACAATCCTT
GGCAATGGCCGCGTCGCGCTGATCCTCGACGTCGCGCGGCTGCACGAGATCGATGCTCGCGGACCGGTCGGGCGGCCGAC
GCCGCGGGATGCCACGAGATCCGAATTTGCAGAGGACATGACCCATGCAGCCTGA

Upstream 100 bases:

>100_bases
GCGATGGCGCCAAGAAGGCCGACGGCAAGGCAGCCGGTGCGACGGGGTGGCTGGTCAAGCCATTCAATCCGGAGCAACTG
ATCGCAACGGTCAACCGCGT

Downstream 100 bases:

>100_bases
CAACAAGCCGGCCGACCATTTTGGCCAGCAAGCGGCCGTCAGCGAGAATGTGCAGCAGTTCATCACCTTCACGCTGGGCG
AGGAGGAGTACGGCATCGAC

Product: chemotaxis protein CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 684; Mature: 683

Protein sequence:

>684_residues
MSVTSEQESYPVAQFRKTYFEECAELLDALQSNLELLSSGQEDDETLHAIFRSVHSIKGGAGAFGCTDLVAFSHTFESLL
DALRDHKIATTNEVKQLLLRASDALADIVNAARLEQQLPADFAADIRSAMQDVLQGAGHPVETKPAPSASDAKLLSEQTY
RIRFRPHTEMLRKANEPLLLIRQLRKLGTLTTEVDFSALPALEALDPEAAYFNWTFTLETAVPRGSIQDVFEFVEDDCDL
QIDLLQTAVPTAEVAVGESSSATAPAAAAVSLAQSIRVDVDKVDRLVNLVGELVISQAMLTEQGMSLPADKYPQLIQGIE
ALAQSARELQESVMAIRAQPVKSVFARMPRIVRELAAVLGKEVRIVTSGEMTEIDKTVIEQLNDPLTHMIRNALDHGIEP
PAERLAAGKPRQGTINLSAAQRSGRIVIEVSDDGRGINRERILEKARARGLVPPGANLTDDEIDNLIFMPAFSTAEVISN
ISGRGVGMDVVKRNVQALGGRISVRSRFGHGSSFTLSLPLTLAVVDGMVVSVGRETFIIPLVAIVENLRPQSADIHPVVG
RGHVLALRGEYLPLVYLHRVFAISDAISDPCRGIVIIVQSESAGRVGIVVDELLGQQQVVVKSLEANYEPVEGISGATIL
GNGRVALILDVARLHEIDARGPVGRPTPRDATRSEFAEDMTHAA

Sequences:

>Translated_684_residues
MSVTSEQESYPVAQFRKTYFEECAELLDALQSNLELLSSGQEDDETLHAIFRSVHSIKGGAGAFGCTDLVAFSHTFESLL
DALRDHKIATTNEVKQLLLRASDALADIVNAARLEQQLPADFAADIRSAMQDVLQGAGHPVETKPAPSASDAKLLSEQTY
RIRFRPHTEMLRKANEPLLLIRQLRKLGTLTTEVDFSALPALEALDPEAAYFNWTFTLETAVPRGSIQDVFEFVEDDCDL
QIDLLQTAVPTAEVAVGESSSATAPAAAAVSLAQSIRVDVDKVDRLVNLVGELVISQAMLTEQGMSLPADKYPQLIQGIE
ALAQSARELQESVMAIRAQPVKSVFARMPRIVRELAAVLGKEVRIVTSGEMTEIDKTVIEQLNDPLTHMIRNALDHGIEP
PAERLAAGKPRQGTINLSAAQRSGRIVIEVSDDGRGINRERILEKARARGLVPPGANLTDDEIDNLIFMPAFSTAEVISN
ISGRGVGMDVVKRNVQALGGRISVRSRFGHGSSFTLSLPLTLAVVDGMVVSVGRETFIIPLVAIVENLRPQSADIHPVVG
RGHVLALRGEYLPLVYLHRVFAISDAISDPCRGIVIIVQSESAGRVGIVVDELLGQQQVVVKSLEANYEPVEGISGATIL
GNGRVALILDVARLHEIDARGPVGRPTPRDATRSEFAEDMTHAA
>Mature_683_residues
SVTSEQESYPVAQFRKTYFEECAELLDALQSNLELLSSGQEDDETLHAIFRSVHSIKGGAGAFGCTDLVAFSHTFESLLD
ALRDHKIATTNEVKQLLLRASDALADIVNAARLEQQLPADFAADIRSAMQDVLQGAGHPVETKPAPSASDAKLLSEQTYR
IRFRPHTEMLRKANEPLLLIRQLRKLGTLTTEVDFSALPALEALDPEAAYFNWTFTLETAVPRGSIQDVFEFVEDDCDLQ
IDLLQTAVPTAEVAVGESSSATAPAAAAVSLAQSIRVDVDKVDRLVNLVGELVISQAMLTEQGMSLPADKYPQLIQGIEA
LAQSARELQESVMAIRAQPVKSVFARMPRIVRELAAVLGKEVRIVTSGEMTEIDKTVIEQLNDPLTHMIRNALDHGIEPP
AERLAAGKPRQGTINLSAAQRSGRIVIEVSDDGRGINRERILEKARARGLVPPGANLTDDEIDNLIFMPAFSTAEVISNI
SGRGVGMDVVKRNVQALGGRISVRSRFGHGSSFTLSLPLTLAVVDGMVVSVGRETFIIPLVAIVENLRPQSADIHPVVGR
GHVLALRGEYLPLVYLHRVFAISDAISDPCRGIVIIVQSESAGRVGIVVDELLGQQQVVVKSLEANYEPVEGISGATILG
NGRVALILDVARLHEIDARGPVGRPTPRDATRSEFAEDMTHAA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=666, Percent_Identity=41.8918918918919, Blast_Score=468, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 74034; Mature: 73903

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTSEQESYPVAQFRKTYFEECAELLDALQSNLELLSSGQEDDETLHAIFRSVHSIKGG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
AGAFGCTDLVAFSHTFESLLDALRDHKIATTNEVKQLLLRASDALADIVNAARLEQQLPA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
DFAADIRSAMQDVLQGAGHPVETKPAPSASDAKLLSEQTYRIRFRPHTEMLRKANEPLLL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCEEEEECCHHHHHHCCCCCHHH
IRQLRKLGTLTTEVDFSALPALEALDPEAAYFNWTFTLETAVPRGSIQDVFEFVEDDCDL
HHHHHHHCCCCCCCCHHHCCHHHHCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHCCCCE
QIDLLQTAVPTAEVAVGESSSATAPAAAAVSLAQSIRVDVDKVDRLVNLVGELVISQAML
EHHHHHHCCCCHHEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
TEQGMSLPADKYPQLIQGIEALAQSARELQESVMAIRAQPVKSVFARMPRIVRELAAVLG
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
KEVRIVTSGEMTEIDKTVIEQLNDPLTHMIRNALDHGIEPPAERLAAGKPRQGTINLSAA
CCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEEEC
QRSGRIVIEVSDDGRGINRERILEKARARGLVPPGANLTDDEIDNLIFMPAFSTAEVISN
CCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHCCEEEECCCHHHHHHHC
ISGRGVGMDVVKRNVQALGGRISVRSRFGHGSSFTLSLPLTLAVVDGMVVSVGRETFIIP
CCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCEEEEECCHHHHHHHHHHHHCCCCHHHHH
LVAIVENLRPQSADIHPVVGRGHVLALRGEYLPLVYLHRVFAISDAISDPCRGIVIIVQS
HHHHHHHCCCCCCCCCEECCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
ESAGRVGIVVDELLGQQQVVVKSLEANYEPVEGISGATILGNGRVALILDVARLHEIDAR
CCCCCEEEHHHHHCCHHHHHHHHHHCCCCCCCCCCCCEEECCCCEEEEEEHHHHHHHCCC
GPVGRPTPRDATRSEFAEDMTHAA
CCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVTSEQESYPVAQFRKTYFEECAELLDALQSNLELLSSGQEDDETLHAIFRSVHSIKGG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
AGAFGCTDLVAFSHTFESLLDALRDHKIATTNEVKQLLLRASDALADIVNAARLEQQLPA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
DFAADIRSAMQDVLQGAGHPVETKPAPSASDAKLLSEQTYRIRFRPHTEMLRKANEPLLL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCEEEEECCHHHHHHCCCCCHHH
IRQLRKLGTLTTEVDFSALPALEALDPEAAYFNWTFTLETAVPRGSIQDVFEFVEDDCDL
HHHHHHHCCCCCCCCHHHCCHHHHCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHCCCCE
QIDLLQTAVPTAEVAVGESSSATAPAAAAVSLAQSIRVDVDKVDRLVNLVGELVISQAML
EHHHHHHCCCCHHEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
TEQGMSLPADKYPQLIQGIEALAQSARELQESVMAIRAQPVKSVFARMPRIVRELAAVLG
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
KEVRIVTSGEMTEIDKTVIEQLNDPLTHMIRNALDHGIEPPAERLAAGKPRQGTINLSAA
CCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEEEC
QRSGRIVIEVSDDGRGINRERILEKARARGLVPPGANLTDDEIDNLIFMPAFSTAEVISN
CCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHCCEEEECCCHHHHHHHC
ISGRGVGMDVVKRNVQALGGRISVRSRFGHGSSFTLSLPLTLAVVDGMVVSVGRETFIIP
CCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCEEEEECCHHHHHHHHHHHHCCCCHHHHH
LVAIVENLRPQSADIHPVVGRGHVLALRGEYLPLVYLHRVFAISDAISDPCRGIVIIVQS
HHHHHHHCCCCCCCCCEECCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
ESAGRVGIVVDELLGQQQVVVKSLEANYEPVEGISGATILGNGRVALILDVARLHEIDAR
CCCCCEEEHHHHHCCHHHHHHHHHHCCCCCCCCCCCCEEECCCCEEEEEEHHHHHHHCCC
GPVGRPTPRDATRSEFAEDMTHAA
CCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7623670; 11481430 [H]