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The map label for this gene is regB [H]

Identifier: 146338790

GI number: 146338790

Start: 1842168

End: 1843562

Strand: Direct

Name: regB [H]

Synonym: BRADO1724

Alternate gene names: 146338790

Gene position: 1842168-1843562 (Clockwise)

Preceding gene: 146338789

Following gene: 146338791

Centisome position: 24.71

GC content: 66.45

Gene sequence:

>1395_bases
ATGCGCCTTGGCGATATCAGCGCTGATCTCGGACGCCGCCGCATGAGGAACGAAGCGCCGAACCTTCCGATCGGAGCGGT
CGCCGCGCTCGCTACGCCCGAGATCCACGCGCCCGTCCCGACCAAGGACGCGACCAACCGCAAGAACATGGTGCTGCTGA
TCCAGCTGCGCTGGATCGCGGTGGTCGGGCAGATCGTCACTATCGCCTTCGTCACCGCTTGGTTCGGCATCGCGCTGCCG
GTCGTACCGATGGCCGCGATCATCTGTGCGCTGGTGGTGCTGAACATCGCCAGCCACATCTGGCTGCGCACCCGCGACGA
CGTCGGCAACCGCGACCTGCTGATCGCGCTGATGCTCGACGTCGTGGCGCTGACGTCGGAGCTCTATCTCACCGGCGGCG
CGTCGAATCCGTTCACCTGTCTCTATCTGCTGCAAGTGACGCTCGGCGCCGTGCTGCTCGATGCGCGCTCGTCGTGGTCG
CTGGTCGCGCTGACCGTGCTCAGTTTCGTCTGGCTCACCATCGAGTATCGGCCGCTCGCGTTGCCGCAGCATCACGTCAG
CGATCCCTTCAGCCTGCACATCACCGGCATGTTCGTCGGCTTCGTGCTCGACGCGGTGCTGCTCGTCGTGTTCGTGACCC
GCATCAATCGGAACCTGCGCGAGCGCGACGCCAAGCTCGCTGATCTGCGCCAGCATGCCGCCGAGCAGGACCACATCATC
CGCATGGGCCTTTTGGCCTCGGGCGCCGCGCACGAGCTCGGCACGCCGCTGGCGTCGATCTCGGTGATCCTCAACGACTG
GCGGCGCATGACCGCGATCTCGGCCGATCCTGCACTGGCGGAGGACTTTACCGAGATGGAAGCCGCAGTGCAGCGCTGCA
AGTCGATCGTGACGGACATTCTGGTGTCTGCCGGACAGGCGCGCGGCGAGGGCTCAGCGCCGACGACATTGAAGACGTTC
CTGGCGACGCTGGTGTCCGAATGGACCGCTGCGCGCTCGGCGCGCAACCTGATGGTCCGCAACGAGTTCGGCTCCGATCC
CACGATCGTCTCCGACGTCGCGCTGAAGCAGGCGATCGTCAACGTGCTCGACAACGCCTTCGAAGTGTCGCGCGAGTGGG
TGGAGCTCGTCGCCGAGCGCGACGGCGATCAGCTGCTGCTCAGCGTCAGCGATCGCGGCCCCGGCTTCGACCCCGCCATG
CTGGCGCAGCTCGGCCGGCCGTATCAGTCGAGCAAGGGCAGGCCCGGGCGCGGCCTCGGCCTGTTCCTGGTGGTCAATGT
GATCCGCAAGCTCGGCGGCGGCGTTTCGGCATGGAACCACCGGGGACGCGGGGCAACCGTGCGGCTATCCTTGCCGCTCT
CGATGCTTGCGATTGGAGAGCCCAGTGGAGATTGA

Upstream 100 bases:

>100_bases
CGCGCGCGCGGCGAGGGCGACCCGGCGGCAGGGCAGGACGTGGAATGGGATCATCGGCAGCAGGACATGCGCAGGCAGGA
GGCGTCGCCATTGTGAGCGA

Downstream 100 bases:

>100_bases
ACGCTCTCTCCTGATTGTCGAGGACGACGACGGCTTTGCGCGCACCTTGAAGCGCTCGTTCGAGCGGCGCGGCTATGAGG
CGGTGATCGCAGCGTCGCTC

Product: two-component sensor histidine kinase photosynthetic apparatus regulatory protein regB (PrrB protein)

Products: NA

Alternate protein names: Protein prrB [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MRLGDISADLGRRRMRNEAPNLPIGAVAALATPEIHAPVPTKDATNRKNMVLLIQLRWIAVVGQIVTIAFVTAWFGIALP
VVPMAAIICALVVLNIASHIWLRTRDDVGNRDLLIALMLDVVALTSELYLTGGASNPFTCLYLLQVTLGAVLLDARSSWS
LVALTVLSFVWLTIEYRPLALPQHHVSDPFSLHITGMFVGFVLDAVLLVVFVTRINRNLRERDAKLADLRQHAAEQDHII
RMGLLASGAAHELGTPLASISVILNDWRRMTAISADPALAEDFTEMEAAVQRCKSIVTDILVSAGQARGEGSAPTTLKTF
LATLVSEWTAARSARNLMVRNEFGSDPTIVSDVALKQAIVNVLDNAFEVSREWVELVAERDGDQLLLSVSDRGPGFDPAM
LAQLGRPYQSSKGRPGRGLGLFLVVNVIRKLGGGVSAWNHRGRGATVRLSLPLSMLAIGEPSGD

Sequences:

>Translated_464_residues
MRLGDISADLGRRRMRNEAPNLPIGAVAALATPEIHAPVPTKDATNRKNMVLLIQLRWIAVVGQIVTIAFVTAWFGIALP
VVPMAAIICALVVLNIASHIWLRTRDDVGNRDLLIALMLDVVALTSELYLTGGASNPFTCLYLLQVTLGAVLLDARSSWS
LVALTVLSFVWLTIEYRPLALPQHHVSDPFSLHITGMFVGFVLDAVLLVVFVTRINRNLRERDAKLADLRQHAAEQDHII
RMGLLASGAAHELGTPLASISVILNDWRRMTAISADPALAEDFTEMEAAVQRCKSIVTDILVSAGQARGEGSAPTTLKTF
LATLVSEWTAARSARNLMVRNEFGSDPTIVSDVALKQAIVNVLDNAFEVSREWVELVAERDGDQLLLSVSDRGPGFDPAM
LAQLGRPYQSSKGRPGRGLGLFLVVNVIRKLGGGVSAWNHRGRGATVRLSLPLSMLAIGEPSGD
>Mature_464_residues
MRLGDISADLGRRRMRNEAPNLPIGAVAALATPEIHAPVPTKDATNRKNMVLLIQLRWIAVVGQIVTIAFVTAWFGIALP
VVPMAAIICALVVLNIASHIWLRTRDDVGNRDLLIALMLDVVALTSELYLTGGASNPFTCLYLLQVTLGAVLLDARSSWS
LVALTVLSFVWLTIEYRPLALPQHHVSDPFSLHITGMFVGFVLDAVLLVVFVTRINRNLRERDAKLADLRQHAAEQDHII
RMGLLASGAAHELGTPLASISVILNDWRRMTAISADPALAEDFTEMEAAVQRCKSIVTDILVSAGQARGEGSAPTTLKTF
LATLVSEWTAARSARNLMVRNEFGSDPTIVSDVALKQAIVNVLDNAFEVSREWVELVAERDGDQLLLSVSDRGPGFDPAM
LAQLGRPYQSSKGRPGRGLGLFLVVNVIRKLGGGVSAWNHRGRGATVRLSLPLSMLAIGEPSGD

Specific function: Member of the two-component regulatory system RegB/RegA. Involved in the positive regulation of photosynthesis gene expression in response to anaerobiosis. Also involved in positive regulation of the cbbI and cbbII Calvin cycle CO2 fixation operons, as we

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87081816, Length=101, Percent_Identity=38.6138613861386, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790436, Length=260, Percent_Identity=27.6923076923077, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790346, Length=220, Percent_Identity=28.6363636363636, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50241; Mature: 50241

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLGDISADLGRRRMRNEAPNLPIGAVAALATPEIHAPVPTKDATNRKNMVLLIQLRWIA
CCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEHHHHH
VVGQIVTIAFVTAWFGIALPVVPMAAIICALVVLNIASHIWLRTRDDVGNRDLLIALMLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHH
VVALTSELYLTGGASNPFTCLYLLQVTLGAVLLDARSSWSLVALTVLSFVWLTIEYRPLA
HHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCC
LPQHHVSDPFSLHITGMFVGFVLDAVLLVVFVTRINRNLRERDAKLADLRQHAAEQDHII
CCHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
RMGLLASGAAHELGTPLASISVILNDWRRMTAISADPALAEDFTEMEAAVQRCKSIVTDI
EHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LVSAGQARGEGSAPTTLKTFLATLVSEWTAARSARNLMVRNEFGSDPTIVSDVALKQAIV
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCHHHHHHHHHHHH
NVLDNAFEVSREWVELVAERDGDQLLLSVSDRGPGFDPAMLAQLGRPYQSSKGRPGRGLG
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCCCHH
LFLVVNVIRKLGGGVSAWNHRGRGATVRLSLPLSMLAIGEPSGD
HHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEEEEEECCCCCC
>Mature Secondary Structure
MRLGDISADLGRRRMRNEAPNLPIGAVAALATPEIHAPVPTKDATNRKNMVLLIQLRWIA
CCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEHHHHH
VVGQIVTIAFVTAWFGIALPVVPMAAIICALVVLNIASHIWLRTRDDVGNRDLLIALMLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHH
VVALTSELYLTGGASNPFTCLYLLQVTLGAVLLDARSSWSLVALTVLSFVWLTIEYRPLA
HHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCC
LPQHHVSDPFSLHITGMFVGFVLDAVLLVVFVTRINRNLRERDAKLADLRQHAAEQDHII
CCHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
RMGLLASGAAHELGTPLASISVILNDWRRMTAISADPALAEDFTEMEAAVQRCKSIVTDI
EHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LVSAGQARGEGSAPTTLKTFLATLVSEWTAARSARNLMVRNEFGSDPTIVSDVALKQAIV
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCHHHHHHHHHHHH
NVLDNAFEVSREWVELVAERDGDQLLLSVSDRGPGFDPAMLAQLGRPYQSSKGRPGRGLG
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCCCHH
LFLVVNVIRKLGGGVSAWNHRGRGATVRLSLPLSMLAIGEPSGD
HHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7751278; 10358089 [H]