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The map label for this gene is cyoB [H]

Identifier: 146338786

GI number: 146338786

Start: 1838324

End: 1840333

Strand: Direct

Name: cyoB [H]

Synonym: BRADO1720

Alternate gene names: 146338786

Gene position: 1838324-1840333 (Clockwise)

Preceding gene: 146338785

Following gene: 146338787

Centisome position: 24.65

GC content: 61.99

Gene sequence:

>2010_bases
ATGTTCGATACAACCAATCTCACAAAAATCATCTTCGGCCGGCTGACCCTGGAGTCGCTGCCGTTGCACGAGCCGATCAT
CGTCGGCACCTTCACCTTGGTTGCGCTCGGCGGCCTCGCGCTGCTCGGCGCGATCACCTACTTCCGTCTCTGGGGCTATC
TCTGGAAGGAGTGGTTCACCACCGTCGACCACAAGCGCATCGGCATCATGTACATGGTGCTCGGCATCGTCATGCTGCTG
CGCGGCTTCGCCGATGCGCTGATGATGCGGTTGCAGCAGGCGATCGCCTTCAACGGCTCCGAGGGCTATCTCAACTCGCA
TCACTATGATCAGGTGTTCACGGCGCACGGCGTGATCATGATCTTCTTCGTCGCGATGCCGCTGGTCACCGGCCTGATGA
ACTATGTCGTGCCGCTGCAGATCGGCGCCCGCGACGTGTCGTTTCCGTTCCTGAACAATTTCAGCTTCTGGATGACCACG
GCCGGCGCCGTGCTGGTGATGTGCTCGCTGTTCGTCGGCGAGTTCGCGCGTACCGGCTGGCTGGCCTATCCGCCGCTGTC
GAACCTGTCTTACAGTCCGGATGTGGGCGTCGATTATTACATCTGGGCGCTGCAGGTCGCCGGCGTCGGTACGCTATTGT
CCGGCGTCAATTTGATCTGCACCATTGTCAAGATGCGTGCGCCCGGCATGACCATGATGAAGATGCCGGTCTTCACCTGG
ACCTCGCTGTGCACCAACGTGCTGATCGTCGCCTCCTTCCCGGTGCTGACGGCGGTACTGGCGCTGCTGTCGCTCGACCG
CTACGTCGGCACCAACTTCTTTACCAATGATTTCGGCGGCGATCCGATGATGTATGTCAACCTCATCTGGATCTGGGGCC
ATCCGGAGGTCTACATCCTGATTCTGCCGGCGTTCGGCATCTTCTCCGAGGTCACCTCGACCTTCTCGGGCAAGCGGCTG
TTCGGCTACACCTCGATGGTCTACGCCACCGTCGTCATCACCATCCTGTCCTACCTGGTCTGGCTGCACCATTTCTTCAC
CATGGGCTCCGGCGCCAGCGTGAACTCGTTCTTCGGCATCACCACGATGATCATCTCGATCCCGACGGGCGCGAAGATGT
TCAACTGGCTGTTCACGATGTATCGCGGCCGCATCCGCTTCGAGCTGCCGATGATGTGGACCGTGGCCTTCATGCTGACC
TTCGTGATCGGCGGCATGACCGGCGTGCTGCTCGCGGTGCCGCCGGCCGACTTCGTGCTGCACAACAGCCTGTTCCTGGT
CGCGCACTTCCACAACGTGATCATCGGCGGCGTGCTATTCGGCCTGTTCGCCGGCATCGCCTACTGGTTCCCGAAGGCGT
TCGGCTTCAAGCTCGATCCGTTCTGGGGCAAGATGTCGTTCTGGTTTTGGACCGTGGGCTTTTACTTCGCCTTCATGCCG
CTCTACGTGCTCGGCCTGATGGGCGTGACGCGACGCCTGCGTACCTTCGATGATCCGAGCCTGCAGATCTGGTTCATCAT
CGCCGGCATCGGCGCGTTCCTGATCCTGCTGGGCATCGCCAGCTTCCTGATCCAGATCGCCGTCAGCGTGCTTCGCCGCG
AGCAGCTCGCCGACACCACCGGCGATCCCTGGGATGCGCGCACCCTGGAGTGGGCGACGTCGTCGCCGCCGCCGGCCTAT
AATTTCGCCTTCACACCCGTCATTCACGACAATGACGCGTGGTGGGACATGAAGCGCCGCGGCTACGTCCGTCCGCTCAC
CGGCTTCAAGGCGATCCACATGCCGAGCAACACCGGCACCGGCGTGATCCTGGCGGGGCTCAGCACGACCATGGCGTTCG
GCCTGATCTGGTACATGTGGTGGATGGCGGCCGGCAGCTTCGTCGCGCTGCTGGCGGTCGCGATCGGCCACACCTTCAAC
TATCACCGCAGCTTCCACATCCCCGCTGATGAGGTCGTCGGCACCGAGCGCGCCCGCACCGAGCTGCTCGCGGCAGGAGC
CAAGTCATGA

Upstream 100 bases:

>100_bases
CTGCAAGGACGCGGGCTGGAGCGGCCCGGCCTGATGCGGCCGTCCAAGGCTTCCTTCATCACGAGGCCCTCCTCGAAGTC
GGATTCGTGAGGATCACACC

Downstream 100 bases:

>100_bases
CGATCGCAGCAGGCACCATGAAGGCCGGCGAGCCGGTCTTCTACGTCGTCGACGAGCACGACCACCCGGAAGGCAGCAGC
ACGCAGCTCGGCTTCTGGAT

Product: cytochrome o ubiquinol oxidase subunit I

Products: NA

Alternate protein names: Cytochrome o subunit 1; Cytochrome o ubiquinol oxidase subunit 1; Oxidase BO(3) subunit 1; Ubiquinol oxidase chain A; Ubiquinol oxidase polypeptide I [H]

Number of amino acids: Translated: 669; Mature: 669

Protein sequence:

>669_residues
MFDTTNLTKIIFGRLTLESLPLHEPIIVGTFTLVALGGLALLGAITYFRLWGYLWKEWFTTVDHKRIGIMYMVLGIVMLL
RGFADALMMRLQQAIAFNGSEGYLNSHHYDQVFTAHGVIMIFFVAMPLVTGLMNYVVPLQIGARDVSFPFLNNFSFWMTT
AGAVLVMCSLFVGEFARTGWLAYPPLSNLSYSPDVGVDYYIWALQVAGVGTLLSGVNLICTIVKMRAPGMTMMKMPVFTW
TSLCTNVLIVASFPVLTAVLALLSLDRYVGTNFFTNDFGGDPMMYVNLIWIWGHPEVYILILPAFGIFSEVTSTFSGKRL
FGYTSMVYATVVITILSYLVWLHHFFTMGSGASVNSFFGITTMIISIPTGAKMFNWLFTMYRGRIRFELPMMWTVAFMLT
FVIGGMTGVLLAVPPADFVLHNSLFLVAHFHNVIIGGVLFGLFAGIAYWFPKAFGFKLDPFWGKMSFWFWTVGFYFAFMP
LYVLGLMGVTRRLRTFDDPSLQIWFIIAGIGAFLILLGIASFLIQIAVSVLRREQLADTTGDPWDARTLEWATSSPPPAY
NFAFTPVIHDNDAWWDMKRRGYVRPLTGFKAIHMPSNTGTGVILAGLSTTMAFGLIWYMWWMAAGSFVALLAVAIGHTFN
YHRSFHIPADEVVGTERARTELLAAGAKS

Sequences:

>Translated_669_residues
MFDTTNLTKIIFGRLTLESLPLHEPIIVGTFTLVALGGLALLGAITYFRLWGYLWKEWFTTVDHKRIGIMYMVLGIVMLL
RGFADALMMRLQQAIAFNGSEGYLNSHHYDQVFTAHGVIMIFFVAMPLVTGLMNYVVPLQIGARDVSFPFLNNFSFWMTT
AGAVLVMCSLFVGEFARTGWLAYPPLSNLSYSPDVGVDYYIWALQVAGVGTLLSGVNLICTIVKMRAPGMTMMKMPVFTW
TSLCTNVLIVASFPVLTAVLALLSLDRYVGTNFFTNDFGGDPMMYVNLIWIWGHPEVYILILPAFGIFSEVTSTFSGKRL
FGYTSMVYATVVITILSYLVWLHHFFTMGSGASVNSFFGITTMIISIPTGAKMFNWLFTMYRGRIRFELPMMWTVAFMLT
FVIGGMTGVLLAVPPADFVLHNSLFLVAHFHNVIIGGVLFGLFAGIAYWFPKAFGFKLDPFWGKMSFWFWTVGFYFAFMP
LYVLGLMGVTRRLRTFDDPSLQIWFIIAGIGAFLILLGIASFLIQIAVSVLRREQLADTTGDPWDARTLEWATSSPPPAY
NFAFTPVIHDNDAWWDMKRRGYVRPLTGFKAIHMPSNTGTGVILAGLSTTMAFGLIWYMWWMAAGSFVALLAVAIGHTFN
YHRSFHIPADEVVGTERARTELLAAGAKS
>Mature_669_residues
MFDTTNLTKIIFGRLTLESLPLHEPIIVGTFTLVALGGLALLGAITYFRLWGYLWKEWFTTVDHKRIGIMYMVLGIVMLL
RGFADALMMRLQQAIAFNGSEGYLNSHHYDQVFTAHGVIMIFFVAMPLVTGLMNYVVPLQIGARDVSFPFLNNFSFWMTT
AGAVLVMCSLFVGEFARTGWLAYPPLSNLSYSPDVGVDYYIWALQVAGVGTLLSGVNLICTIVKMRAPGMTMMKMPVFTW
TSLCTNVLIVASFPVLTAVLALLSLDRYVGTNFFTNDFGGDPMMYVNLIWIWGHPEVYILILPAFGIFSEVTSTFSGKRL
FGYTSMVYATVVITILSYLVWLHHFFTMGSGASVNSFFGITTMIISIPTGAKMFNWLFTMYRGRIRFELPMMWTVAFMLT
FVIGGMTGVLLAVPPADFVLHNSLFLVAHFHNVIIGGVLFGLFAGIAYWFPKAFGFKLDPFWGKMSFWFWTVGFYFAFMP
LYVLGLMGVTRRLRTFDDPSLQIWFIIAGIGAFLILLGIASFLIQIAVSVLRREQLADTTGDPWDARTLEWATSSPPPAY
NFAFTPVIHDNDAWWDMKRRGYVRPLTGFKAIHMPSNTGTGVILAGLSTTMAFGLIWYMWWMAAGSFVALLAVAIGHTFN
YHRSFHIPADEVVGTERARTELLAAGAKS

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration. This ubiquinol oxidase shows proton pump activity across the membrane in addition to the electron transfer [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=513, Percent_Identity=38.5964912280702, Blast_Score=337, Evalue=2e-92,
Organism=Escherichia coli, GI1786634, Length=662, Percent_Identity=64.1993957703928, Blast_Score=889, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=537, Percent_Identity=38.1750465549348, Blast_Score=347, Evalue=3e-96,
Organism=Saccharomyces cerevisiae, GI6226524, Length=325, Percent_Identity=44.3076923076923, Blast_Score=250, Evalue=5e-67,
Organism=Saccharomyces cerevisiae, GI6226523, Length=248, Percent_Identity=37.9032258064516, Blast_Score=142, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014207 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 74878; Mature: 74878

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB ; PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCCC
>Mature Secondary Structure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HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]