Click here to switch to the map view.

The map label for this gene is mocR [H]

Identifier: 146338627

GI number: 146338627

Start: 1663786

End: 1665141

Strand: Direct

Name: mocR [H]

Synonym: BRADO1555

Alternate gene names: 146338627

Gene position: 1663786-1665141 (Clockwise)

Preceding gene: 146338625

Following gene: 146338639

Centisome position: 22.31

GC content: 68.95

Gene sequence:

>1356_bases
TTGCGCAGCGGCATCGTCGGCGGTCTGCTGGCTTCTGGCCTGCGGTTGCCGTCGACGCGCGCGCTCGCAGAGCAGCTCGG
CGTCCGGCGAAACGCGATCGTCGCAGCCTATGAGGCTCTGCTGTCGGACGGTCTGGTGGAGGCGCGGCACGGTGCGGGCA
CCTATGTCGCTGCTCGGTTGCCGACGCCGCAGACGGCGGCTCCAGCCGCCGAGCTGGAGATCAGGATTCCGCAAACCCGG
CCGTTCGCGCTCGGCGTGACGCTCGTCGATCCGGTCTTGTTGAAGCGGCTGGCCGCGGCAAGCCGTCGCCGGATTGCACA
GGCCGCGCCCGCTGCGCTCGGCTACGCCGATCCGAGGGGTAGCTTGCATCTGCGCACGCAAGTCGCGCACTACCTTGCCG
CCAATCGCGGCGTCCGCTGCGATCCGAGCTGCATCCTGATCGTCAGCGGCACCCAGCATGGCCTGCGGCTGTGCATCGAT
GCATTGCTGACGCCTGGAGACGCAGTCTGGTTCGAGGATCCCGGCTACGTCGCCTCGCGCCATACGTTGAGCACGACGGG
GACGAAGCTGGTGCCTGTCCCGGTCGACGGCGAAGGCCTCGTTGTGAGCGCCGGGGAGAAGGCCGATGCACGCGCGAAGG
CCGTCTACGTCACGCCCTCGCATCAGTTCCCCACGGGAGTTGCGATGAGCATGGCGCGTCGCATCGCGCTGCTCGACTGG
GCACGGCGGGCGGACGCCTATATTTTCGAGGACGATTACGACAGCGAGTATCGCTTCGCCGGCCCGCCGCTGACCGCCTT
GGCCGGCATCGGCGGGGAGCGCGTGATCTATCTCGGCACGTTCGGCAAGACGCTGTTCGCGGGATTGCGGCTCGGCTATC
TCGTGGTGCCGCCCGCCCTGGTGGCCCGCGTGGTCGCTGCGCGCGCGGCGCAGGACCGGTTTCCGCCAGCCTTCATGCAG
GATGCACTCGCCGACCTGATGACCGACGGTGTGATTGCAGCCCACATGCGGCGGATGCGTCCGCGTTACAGGCAGGCCCG
CGATGTGCTCACCGAGGCGCTCGCCAGGCACGCCAAGGGATCTCTGCTGTTATCCGCGCCGGCCCAGGGCCTGCACCTGC
TTGCGACATTGCCGCCGGGAACGGCGAAGGGCGCGGCGCGGTTGATTCGCGAGCGCGCCGGTGTCGAATGCCGCCTGCTG
TCGGACGCGCGGATCGTGCAGCGCGGCCTGGACGGTTTCATCCTCGGCTATTCGGGCTTTGCCGCCAAGGATCTCTCCGA
CGCCGCGCGGCGCCTCGGGCGCGCGACGCAGGAGGTGCTGCGGGAATCGAGCTCTCCGCGAGGTCAGAAGATGTAG

Upstream 100 bases:

>100_bases
AAATAAGGCAACCACTTCGCGGCGCCGCGACGATGCGCTGGCGCTGCCCATCGTACTCGACCGTACGATCCGCAGCCAAT
CTTTGCAGGTGCACGGTGCG

Downstream 100 bases:

>100_bases
TCGATGAAGAGCTGCTGCTGCGGGGCGCTGAACGCCTTCGGCAGCGGGCCCGCTTGCGGATTTGCCGGAGCCTCCGCGCC
GGCCGCGACCTGGTCGCTGC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MRSGIVGGLLASGLRLPSTRALAEQLGVRRNAIVAAYEALLSDGLVEARHGAGTYVAARLPTPQTAAPAAELEIRIPQTR
PFALGVTLVDPVLLKRLAAASRRRIAQAAPAALGYADPRGSLHLRTQVAHYLAANRGVRCDPSCILIVSGTQHGLRLCID
ALLTPGDAVWFEDPGYVASRHTLSTTGTKLVPVPVDGEGLVVSAGEKADARAKAVYVTPSHQFPTGVAMSMARRIALLDW
ARRADAYIFEDDYDSEYRFAGPPLTALAGIGGERVIYLGTFGKTLFAGLRLGYLVVPPALVARVVAARAAQDRFPPAFMQ
DALADLMTDGVIAAHMRRMRPRYRQARDVLTEALARHAKGSLLLSAPAQGLHLLATLPPGTAKGAARLIRERAGVECRLL
SDARIVQRGLDGFILGYSGFAAKDLSDAARRLGRATQEVLRESSSPRGQKM

Sequences:

>Translated_451_residues
MRSGIVGGLLASGLRLPSTRALAEQLGVRRNAIVAAYEALLSDGLVEARHGAGTYVAARLPTPQTAAPAAELEIRIPQTR
PFALGVTLVDPVLLKRLAAASRRRIAQAAPAALGYADPRGSLHLRTQVAHYLAANRGVRCDPSCILIVSGTQHGLRLCID
ALLTPGDAVWFEDPGYVASRHTLSTTGTKLVPVPVDGEGLVVSAGEKADARAKAVYVTPSHQFPTGVAMSMARRIALLDW
ARRADAYIFEDDYDSEYRFAGPPLTALAGIGGERVIYLGTFGKTLFAGLRLGYLVVPPALVARVVAARAAQDRFPPAFMQ
DALADLMTDGVIAAHMRRMRPRYRQARDVLTEALARHAKGSLLLSAPAQGLHLLATLPPGTAKGAARLIRERAGVECRLL
SDARIVQRGLDGFILGYSGFAAKDLSDAARRLGRATQEVLRESSSPRGQKM
>Mature_451_residues
MRSGIVGGLLASGLRLPSTRALAEQLGVRRNAIVAAYEALLSDGLVEARHGAGTYVAARLPTPQTAAPAAELEIRIPQTR
PFALGVTLVDPVLLKRLAAASRRRIAQAAPAALGYADPRGSLHLRTQVAHYLAANRGVRCDPSCILIVSGTQHGLRLCID
ALLTPGDAVWFEDPGYVASRHTLSTTGTKLVPVPVDGEGLVVSAGEKADARAKAVYVTPSHQFPTGVAMSMARRIALLDW
ARRADAYIFEDDYDSEYRFAGPPLTALAGIGGERVIYLGTFGKTLFAGLRLGYLVVPPALVARVVAARAAQDRFPPAFMQ
DALADLMTDGVIAAHMRRMRPRYRQARDVLTEALARHAKGSLLLSAPAQGLHLLATLPPGTAKGAARLIRERAGVECRLL
SDARIVQRGLDGFILGYSGFAAKDLSDAARRLGRATQEVLRESSSPRGQKM

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=269, Percent_Identity=26.7657992565056, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI33469970, Length=269, Percent_Identity=26.7657992565056, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1790797, Length=405, Percent_Identity=28.641975308642, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI1787710, Length=406, Percent_Identity=27.0935960591133, Blast_Score=99, Evalue=6e-22,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 48108; Mature: 48108

Theoretical pI: Translated: 10.52; Mature: 10.52

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSGIVGGLLASGLRLPSTRALAEQLGVRRNAIVAAYEALLSDGLVEARHGAGTYVAARL
CCCCCHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHCCCCCCEEEEEC
PTPQTAAPAAELEIRIPQTRPFALGVTLVDPVLLKRLAAASRRRIAQAAPAALGYADPRG
CCCCCCCCCCEEEEECCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCC
SLHLRTQVAHYLAANRGVRCDPSCILIVSGTQHGLRLCIDALLTPGDAVWFEDPGYVASR
CEEHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEECCCCCEECC
HTLSTTGTKLVPVPVDGEGLVVSAGEKADARAKAVYVTPSHQFPTGVAMSMARRIALLDW
CEEECCCCEEEEEEECCCCEEEECCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHH
ARRADAYIFEDDYDSEYRFAGPPLTALAGIGGERVIYLGTFGKTLFAGLRLGYLVVPPAL
HHHCCCEEEECCCCCCCEECCCCHHHHHCCCCCEEEEEECCHHHHHHHHHHCHHCCCHHH
VARVVAARAAQDRFPPAFMQDALADLMTDGVIAAHMRRMRPRYRQARDVLTEALARHAKG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCC
SLLLSAPAQGLHLLATLPPGTAKGAARLIRERAGVECRLLSDARIVQRGLDGFILGYSGF
CEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECHHHHHHHCCCCEEEECCCC
AAKDLSDAARRLGRATQEVLRESSSPRGQKM
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRSGIVGGLLASGLRLPSTRALAEQLGVRRNAIVAAYEALLSDGLVEARHGAGTYVAARL
CCCCCHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHCCCCCCEEEEEC
PTPQTAAPAAELEIRIPQTRPFALGVTLVDPVLLKRLAAASRRRIAQAAPAALGYADPRG
CCCCCCCCCCEEEEECCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCC
SLHLRTQVAHYLAANRGVRCDPSCILIVSGTQHGLRLCIDALLTPGDAVWFEDPGYVASR
CEEHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEECCCCCEECC
HTLSTTGTKLVPVPVDGEGLVVSAGEKADARAKAVYVTPSHQFPTGVAMSMARRIALLDW
CEEECCCCEEEEEEECCCCEEEECCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHH
ARRADAYIFEDDYDSEYRFAGPPLTALAGIGGERVIYLGTFGKTLFAGLRLGYLVVPPAL
HHHCCCEEEECCCCCCCEECCCCHHHHHCCCCCEEEEEECCHHHHHHHHHHCHHCCCHHH
VARVVAARAAQDRFPPAFMQDALADLMTDGVIAAHMRRMRPRYRQARDVLTEALARHAKG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCC
SLLLSAPAQGLHLLATLPPGTAKGAARLIRERAGVECRLLSDARIVQRGLDGFILGYSGF
CEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECHHHHHHHCCCCEEEECCCC
AAKDLSDAARRLGRATQEVLRESSSPRGQKM
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]