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The map label for this gene is lip2 [H]

Identifier: 146338582

GI number: 146338582

Start: 1612721

End: 1613647

Strand: Direct

Name: lip2 [H]

Synonym: BRADO1504

Alternate gene names: 146338582

Gene position: 1612721-1613647 (Clockwise)

Preceding gene: 146338579

Following gene: 146338584

Centisome position: 21.63

GC content: 67.75

Gene sequence:

>927_bases
ATGTTTCGTTCGACACTTGCCGTTCTGCTGGTGACGAGCCTGTGGCTCGTGCAGTCCATCTCGCTTTCACCGGCGCATGC
AGGTGCTTTCCTGGAGCGTTGGCAAGCGCGGATGGCCGCACGCGAGGTCGACGGTCAAAACGCGCCGGCCGCAGAATATG
TCTATGGCGCCGATCCGCTACAGACGCTCGATTATTGGCAGGCGAGGGCGGGCGTCGCCGCGCCGCTGATCGTATTTGTG
CATGGCGGTGGCTGGAAGCGCGGTGACAAGCGCAACGCGACCGGGGCTGAGAAGGTCGCGCATCTCCTGGCGCAGGGCTA
TGCCTTCGCGTCTATCGACTATCGCCTCGTTCCGGAAGCAACCGTGGAGCAGCAGGCCTCGGACGTTGCCGCGGCCGTGG
CGTGGTTGCGTACCAATTCGGAGCGGTTGGGGATCAATCCGGCGCGCATCGTGCTGATGGGGCACAGCGCCGGCGCGCAT
CTCGTGGCGCTGGTCGGGACCGATCCGCGCTACTTGCGCGCGGTCGGGCTGTCGTTGCGCGACGTCAGCGGCATCATCGC
GCTGGATGGCGCATGCTACGACGTGGCGCGCCAGCTCTCCGATAGCGGGCGCTTCATGATCGACACCTACATCCAGGCGT
TCGGCACCGACCCCGCGCGCCAGCGGGCGCTGTCGCCGACGCTGCAGGCCGCAAAGCCGAACGCGCCGGCGTTCCTGATC
CTCCATGTCGACCGCGCCGACGGCAAGGCGCAGTCCGAGGCGCTCGGCGCTGCCCTGGCGCAGGCGGGCACGCCGGCCGA
GGTCCAGGGCGTCGGCGGCACCGGCCTGCGCGGCCACATGGAGATCAACCGCGAGCTCGGCGATCCCAACTATCCGGCCA
CCGCGATCGTCGATGCCTGGTTGCGCAAGATGATCGGCACGAAGTGA

Upstream 100 bases:

>100_bases
TTTCGCGGACGTGCCCGTTCGTAGCAATTTGTAACAGCGCTAGCTGCTGCCTCCATTAAACACCGCGTGCTGCTATCGTC
ACGCGACCAAGGAGCATGCG

Downstream 100 bases:

>100_bases
CATTCACGGCGCCGCCGCCGTCCTGACGGCACGACGGTGACGCTGGACCATCTGCCCGGACGCGGCGCCGCGCCGCCCGT
CCTATGGTCGACGTGACATC

Product: putative para-nitrobenzyl esterase

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MFRSTLAVLLVTSLWLVQSISLSPAHAGAFLERWQARMAAREVDGQNAPAAEYVYGADPLQTLDYWQARAGVAAPLIVFV
HGGGWKRGDKRNATGAEKVAHLLAQGYAFASIDYRLVPEATVEQQASDVAAAVAWLRTNSERLGINPARIVLMGHSAGAH
LVALVGTDPRYLRAVGLSLRDVSGIIALDGACYDVARQLSDSGRFMIDTYIQAFGTDPARQRALSPTLQAAKPNAPAFLI
LHVDRADGKAQSEALGAALAQAGTPAEVQGVGGTGLRGHMEINRELGDPNYPATAIVDAWLRKMIGTK

Sequences:

>Translated_308_residues
MFRSTLAVLLVTSLWLVQSISLSPAHAGAFLERWQARMAAREVDGQNAPAAEYVYGADPLQTLDYWQARAGVAAPLIVFV
HGGGWKRGDKRNATGAEKVAHLLAQGYAFASIDYRLVPEATVEQQASDVAAAVAWLRTNSERLGINPARIVLMGHSAGAH
LVALVGTDPRYLRAVGLSLRDVSGIIALDGACYDVARQLSDSGRFMIDTYIQAFGTDPARQRALSPTLQAAKPNAPAFLI
LHVDRADGKAQSEALGAALAQAGTPAEVQGVGGTGLRGHMEINRELGDPNYPATAIVDAWLRKMIGTK
>Mature_308_residues
MFRSTLAVLLVTSLWLVQSISLSPAHAGAFLERWQARMAAREVDGQNAPAAEYVYGADPLQTLDYWQARAGVAAPLIVFV
HGGGWKRGDKRNATGAEKVAHLLAQGYAFASIDYRLVPEATVEQQASDVAAAVAWLRTNSERLGINPARIVLMGHSAGAH
LVALVGTDPRYLRAVGLSLRDVSGIIALDGACYDVARQLSDSGRFMIDTYIQAFGTDPARQRALSPTLQAAKPNAPAFLI
LHVDRADGKAQSEALGAALAQAGTPAEVQGVGGTGLRGHMEINRELGDPNYPATAIVDAWLRKMIGTK

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Drosophila melanogaster, GI19920830, Length=167, Percent_Identity=29.3413173652695, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 32791; Mature: 32791

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRSTLAVLLVTSLWLVQSISLSPAHAGAFLERWQARMAAREVDGQNAPAAEYVYGADPL
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHH
QTLDYWQARAGVAAPLIVFVHGGGWKRGDKRNATGAEKVAHLLAQGYAFASIDYRLVPEA
HHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECEEECCCH
TVEQQASDVAAAVAWLRTNSERLGINPARIVLMGHSAGAHLVALVGTDPRYLRAVGLSLR
HHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEEECCCHHHHHHHCCCHH
DVSGIIALDGACYDVARQLSDSGRFMIDTYIQAFGTDPARQRALSPTLQAAKPNAPAFLI
HCCCEEEECCHHHHHHHHHCCCCCEEHHHHHHHHCCCHHHHHHCCCHHHCCCCCCCEEEE
LHVDRADGKAQSEALGAALAQAGTPAEVQGVGGTGLRGHMEINRELGDPNYPATAIVDAW
EEEECCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEHHHCCCCCCCHHHHHHHH
LRKMIGTK
HHHHHCCC
>Mature Secondary Structure
MFRSTLAVLLVTSLWLVQSISLSPAHAGAFLERWQARMAAREVDGQNAPAAEYVYGADPL
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHH
QTLDYWQARAGVAAPLIVFVHGGGWKRGDKRNATGAEKVAHLLAQGYAFASIDYRLVPEA
HHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECEEECCCH
TVEQQASDVAAAVAWLRTNSERLGINPARIVLMGHSAGAHLVALVGTDPRYLRAVGLSLR
HHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEEECCCHHHHHHHCCCHH
DVSGIIALDGACYDVARQLSDSGRFMIDTYIQAFGTDPARQRALSPTLQAAKPNAPAFLI
HCCCEEEECCHHHHHHHHHCCCCCEEHHHHHHHHCCCHHHHHHCCCHHHCCCCCCCEEEE
LHVDRADGKAQSEALGAALAQAGTPAEVQGVGGTGLRGHMEINRELGDPNYPATAIVDAW
EEEECCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEHHHCCCCCCCHHHHHHHH
LRKMIGTK
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1907455 [H]