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The map label for this gene is etrA [H]

Identifier: 146338326

GI number: 146338326

Start: 1308504

End: 1309220

Strand: Reverse

Name: etrA [H]

Synonym: BRADO1231

Alternate gene names: 146338326

Gene position: 1309220-1308504 (Counterclockwise)

Preceding gene: 146338328

Following gene: 146338323

Centisome position: 17.56

GC content: 68.34

Gene sequence:

>717_bases
ATGGCTTCTATCGACCGCTCCCTGGTCGCGCATCTGCCGCTGTTCGCGGGCCTCTCGCCTGAGGATCTCGCCGAGGTGCT
GCGCGAGGCGCGCTCCATGCGCGTCCCTCGCAACAGTGCGGTGTTCGAGCAGGGCGCGGATGCGACGTCGTTCTTCCTGC
TGCTGCACGGCCATGTCCGCGCCAGCAAGACGACGCCGACTGGTGACCAGATCGTCGTCCGCTACGTCGTGCCCGGCGAC
ACGTTCGGCGTCGCCCCCGCCATCGGGCTGCAGCATTATCCGGCGACGGCGACCGCGGTCGATGACAGCGTCGTGCTGGC
TTGGCCGTCGGTGGCGTGGCCGCGGCTGGTCGCGCGGTTCCCGTCGCTGGCCGCAAACACCTTGCAGACGGTCGGCCAGC
GGCTGCAGGAGACTCACGCGCGCGTCGTCGAGATGTCGACACAGCAGGTCGAGCAGCGCATCGCGCACGCGCTGCTGAGG
CTCGCCAACCAGGCTGGGCGCAAGCTCGACCACGGCGTACAGATCGACTTTCCGATCAGCCGGCAGGACATCGCGCAGAT
GACCGGCACCACGCTGCACACCGTGAGCCGCATCCTGTCAGGATGGGAGCAACTCGGCCTCGTCGAAAGCGGCCGTCAGA
AGATCGTGCTGCGCGAGCCGCACAAGATCGTGCTGCTGGCCGAGCAGACGTCCGACGCGACCGCATCGCGATCCTGA

Upstream 100 bases:

>100_bases
CGGCCCGCTCGCAGCGGGTTGTGCCAGCACAAACTTCCGGCCGATCGCAAAACCGTGCTAAGGGCGAGACGAACGTCGCC
CTGCCCGGCCGGAGATCATC

Downstream 100 bases:

>100_bases
TCAGGTGCAGGCGCACAGCGCTGAGAGAAAAGTGTCCGCGTCGACGCCGTGCTCACGGCACGCATCCGCGACGTTGTGAA
AGCAGGCGATCGGGCAGCCG

Product: CRP/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MASIDRSLVAHLPLFAGLSPEDLAEVLREARSMRVPRNSAVFEQGADATSFFLLLHGHVRASKTTPTGDQIVVRYVVPGD
TFGVAPAIGLQHYPATATAVDDSVVLAWPSVAWPRLVARFPSLAANTLQTVGQRLQETHARVVEMSTQQVEQRIAHALLR
LANQAGRKLDHGVQIDFPISRQDIAQMTGTTLHTVSRILSGWEQLGLVESGRQKIVLREPHKIVLLAEQTSDATASRS

Sequences:

>Translated_238_residues
MASIDRSLVAHLPLFAGLSPEDLAEVLREARSMRVPRNSAVFEQGADATSFFLLLHGHVRASKTTPTGDQIVVRYVVPGD
TFGVAPAIGLQHYPATATAVDDSVVLAWPSVAWPRLVARFPSLAANTLQTVGQRLQETHARVVEMSTQQVEQRIAHALLR
LANQAGRKLDHGVQIDFPISRQDIAQMTGTTLHTVSRILSGWEQLGLVESGRQKIVLREPHKIVLLAEQTSDATASRS
>Mature_237_residues
ASIDRSLVAHLPLFAGLSPEDLAEVLREARSMRVPRNSAVFEQGADATSFFLLLHGHVRASKTTPTGDQIVVRYVVPGDT
FGVAPAIGLQHYPATATAVDDSVVLAWPSVAWPRLVARFPSLAANTLQTVGQRLQETHARVVEMSTQQVEQRIAHALLRL
ANQAGRKLDHGVQIDFPISRQDIAQMTGTTLHTVSRILSGWEQLGLVESGRQKIVLREPHKIVLLAEQTSDATASRS

Specific function: Regulates anaerobic growth on fumarate, nitrite, Fe(3+), TMAO, DMSO, thiosulfate and sulfite, but not on nitrate nor Mn(4+) [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=202, Percent_Identity=21.2871287128713, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 25945; Mature: 25814

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASIDRSLVAHLPLFAGLSPEDLAEVLREARSMRVPRNSAVFEQGADATSFFLLLHGHVR
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHCCCCC
ASKTTPTGDQIVVRYVVPGDTFGVAPAIGLQHYPATATAVDDSVVLAWPSVAWPRLVARF
CCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHHCCCCCEEEECCCCHHHHHHHHH
PSLAANTLQTVGQRLQETHARVVEMSTQQVEQRIAHALLRLANQAGRKLDHGVQIDFPIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
RQDIAQMTGTTLHTVSRILSGWEQLGLVESGRQKIVLREPHKIVLLAEQTSDATASRS
HHHHHHHHCHHHHHHHHHHHHHHHHCHHHCCCCEEEEECCCEEEEEEECCCCCCCCCC
>Mature Secondary Structure 
ASIDRSLVAHLPLFAGLSPEDLAEVLREARSMRVPRNSAVFEQGADATSFFLLLHGHVR
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHCCCCC
ASKTTPTGDQIVVRYVVPGDTFGVAPAIGLQHYPATATAVDDSVVLAWPSVAWPRLVARF
CCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHHCCCCCEEEECCCCHHHHHHHHH
PSLAANTLQTVGQRLQETHARVVEMSTQQVEQRIAHALLRLANQAGRKLDHGVQIDFPIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
RQDIAQMTGTTLHTVSRILSGWEQLGLVESGRQKIVLREPHKIVLLAEQTSDATASRS
HHHHHHHHCHHHHHHHHHHHHHHHHCHHHCCCCEEEEECCCEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8253682; 12368813 [H]