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The map label for this gene is chaA [C]

Identifier: 146338297

GI number: 146338297

Start: 1277588

End: 1278712

Strand: Direct

Name: chaA [C]

Synonym: BRADO1201

Alternate gene names: 146338297

Gene position: 1277588-1278712 (Clockwise)

Preceding gene: 146338296

Following gene: 146338298

Centisome position: 17.13

GC content: 64.27

Gene sequence:

>1125_bases
ATGAATGAATTTCAGGAGCGCGGAATCATGAGCGTGAAGGGTCCCACGCCAGCAACCTCGGTCATCTTCCCCGGCCTTGC
CGTCGCGCTGGTCGTCGGCGTCACGGCATTACACTACGATTTTACGCCCTCGGCCGCCGGGCTGGTCTTCGCCGCGGTGC
TGCTGATCGTCCTGTTCGGGACGGTGTTCGCGGCGGTGCATCACGCCGAGGTGATCGCGCACGAAATCGGCGAGCCGTTC
GGCACGCTGCTCCTGACCCTGGCGGTGACGGTCATCGAGGTGGCGCTGATCGCCACGATCATGCTCGGCGACAAGGCCGC
GCCGGCACTGGCACGCGATACGGTGTTTGCCGTCGTCATGATCGTCTGCAACGGCCTGGTCGGCCTCTGCGTCTTCATCG
GCGGCCTGCGCTACCGCGAGCAGGACGTGCTGGTGTCCGGCGCAAATCTGTATCTCAGCGTATTGTTCACGATGGCGACC
ATCACGCTGGTGCTGCCGAACTATACGCTGACCTCGCCGGGGCCGGTGTATTCGGCGGCGCAGCTCGCTTTCGTCAGCGT
GGTGACGATCCTGCTCTATGCCGTGTTCCTGTACACGCAGACGACACGGCACCGGGATTACTTCGTCGGCGAATCCGCCG
GTTTTGCCGACGACGATGTCAGGCTTCCGCGGGGAAAGCTCCTGCTCAGCATCGGGCTGCTGCTGGTCGCGCTGCTCGCC
GTCGTGCTGCTGGCGAAGAAGTTCTCGCTGGTCGTGGACGCCGGCGTCGCGGCGACCGGCTCACCGCCCGCAGTCGCCGG
CGTGCTGGTAGCGCTGCTGATCCTGCTTCCCGAAAGCGTCGCCGCGATCTCCGCGGCGCGCGCCAACGACCTGCAGAAGA
GCATCAACCTGGCGCTCGGCTCCTCGCTGGCCACCATCGGTCTGACCATTCCCGCAGTGGCGGTGACAGCCTATGCGCTC
GACAAGCAATTGGTGCTCGGGCTCGACGCCCAGGGTATGGTGCTTCTGGTCCTGACCTTCGTTTTGAGCATGCTGACCTT
CGGCACCGGCAGAACCAATATCCTGTTCGGGCTGGTGCACATGGTCGTGTTCGCGATATTCCTCTTCCTGCTCTTCGTGC
CCTGA

Upstream 100 bases:

>100_bases
CCGCATTGAAGTTGTTTCGGCCGCCATCCGAGGTTGCGTCGGTGGAGACCCGTCATGTCGGGACCCGCGTGACGCGTGCT
TTGCCATCGCGCATAGTCGA

Downstream 100 bases:

>100_bases
TTTGAGAGACATTCCCATGCTCAGCGCCCAGTCCGACGTCCAGGTCGATACGCCCGAGGTTCGTGTCACTGAATGGAGGT
TGGCACCGGGCAGCGCGACC

Product: putative ionic transporter y4hA

Products: Na (I) [Periplasm]; Ca (II) [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MNEFQERGIMSVKGPTPATSVIFPGLAVALVVGVTALHYDFTPSAAGLVFAAVLLIVLFGTVFAAVHHAEVIAHEIGEPF
GTLLLTLAVTVIEVALIATIMLGDKAAPALARDTVFAVVMIVCNGLVGLCVFIGGLRYREQDVLVSGANLYLSVLFTMAT
ITLVLPNYTLTSPGPVYSAAQLAFVSVVTILLYAVFLYTQTTRHRDYFVGESAGFADDDVRLPRGKLLLSIGLLLVALLA
VVLLAKKFSLVVDAGVAATGSPPAVAGVLVALLILLPESVAAISAARANDLQKSINLALGSSLATIGLTIPAVAVTAYAL
DKQLVLGLDAQGMVLLVLTFVLSMLTFGTGRTNILFGLVHMVVFAIFLFLLFVP

Sequences:

>Translated_374_residues
MNEFQERGIMSVKGPTPATSVIFPGLAVALVVGVTALHYDFTPSAAGLVFAAVLLIVLFGTVFAAVHHAEVIAHEIGEPF
GTLLLTLAVTVIEVALIATIMLGDKAAPALARDTVFAVVMIVCNGLVGLCVFIGGLRYREQDVLVSGANLYLSVLFTMAT
ITLVLPNYTLTSPGPVYSAAQLAFVSVVTILLYAVFLYTQTTRHRDYFVGESAGFADDDVRLPRGKLLLSIGLLLVALLA
VVLLAKKFSLVVDAGVAATGSPPAVAGVLVALLILLPESVAAISAARANDLQKSINLALGSSLATIGLTIPAVAVTAYAL
DKQLVLGLDAQGMVLLVLTFVLSMLTFGTGRTNILFGLVHMVVFAIFLFLLFVP
>Mature_374_residues
MNEFQERGIMSVKGPTPATSVIFPGLAVALVVGVTALHYDFTPSAAGLVFAAVLLIVLFGTVFAAVHHAEVIAHEIGEPF
GTLLLTLAVTVIEVALIATIMLGDKAAPALARDTVFAVVMIVCNGLVGLCVFIGGLRYREQDVLVSGANLYLSVLFTMAT
ITLVLPNYTLTSPGPVYSAAQLAFVSVVTILLYAVFLYTQTTRHRDYFVGESAGFADDDVRLPRGKLLLSIGLLLVALLA
VVLLAKKFSLVVDAGVAATGSPPAVAGVLVALLILLPESVAAISAARANDLQKSINLALGSSLATIGLTIPAVAVTAYAL
DKQLVLGLDAQGMVLLVLTFVLSMLTFGTGRTNILFGLVHMVVFAIFLFLLFVP

Specific function: Possible cation transporter [H]

COG id: COG0387

COG function: function code P; Ca2+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Escherichia coli, GI1787468, Length=379, Percent_Identity=35.6200527704486, Blast_Score=202, Evalue=3e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004713
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 39124; Mature: 39124

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEFQERGIMSVKGPTPATSVIFPGLAVALVVGVTALHYDFTPSAAGLVFAAVLLIVLFG
CCCHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHH
TVFAAVHHAEVIAHEIGEPFGTLLLTLAVTVIEVALIATIMLGDKAAPALARDTVFAVVM
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
IVCNGLVGLCVFIGGLRYREQDVLVSGANLYLSVLFTMATITLVLPNYTLTSPGPVYSAA
HHHHHHHHHHHHHCCCCCCCCHHEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
QLAFVSVVTILLYAVFLYTQTTRHRDYFVGESAGFADDDVRLPRGKLLLSIGLLLVALLA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
VVLLAKKFSLVVDAGVAATGSPPAVAGVLVALLILLPESVAAISAARANDLQKSINLALG
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHC
SSLATIGLTIPAVAVTAYALDKQLVLGLDAQGMVLLVLTFVLSMLTFGTGRTNILFGLVH
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
MVVFAIFLFLLFVP
HHHHHHHHHHHHCC
>Mature Secondary Structure
MNEFQERGIMSVKGPTPATSVIFPGLAVALVVGVTALHYDFTPSAAGLVFAAVLLIVLFG
CCCHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHH
TVFAAVHHAEVIAHEIGEPFGTLLLTLAVTVIEVALIATIMLGDKAAPALARDTVFAVVM
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
IVCNGLVGLCVFIGGLRYREQDVLVSGANLYLSVLFTMATITLVLPNYTLTSPGPVYSAA
HHHHHHHHHHHHHCCCCCCCCHHEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
QLAFVSVVTILLYAVFLYTQTTRHRDYFVGESAGFADDDVRLPRGKLLLSIGLLLVALLA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
VVLLAKKFSLVVDAGVAATGSPPAVAGVLVALLILLPESVAAISAARANDLQKSINLALG
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHC
SSLATIGLTIPAVAVTAYALDKQLVLGLDAQGMVLLVLTFVLSMLTFGTGRTNILFGLVH
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
MVVFAIFLFLLFVP
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Cytoplasm]; Proton [Periplasm]; Ca (II) [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: Na (I) [Cytoplasm] + Proton [Periplasm] = Proton [Cytoplasm] + Na (I) [Periplasm] Ca (II) [Cytoplasm] + Proton [Periplasm] = Ca (II) [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]