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The map label for this gene is yfhR [C]

Identifier: 146338295

GI number: 146338295

Start: 1275249

End: 1276061

Strand: Direct

Name: yfhR [C]

Synonym: BRADO1199

Alternate gene names: 146338295

Gene position: 1275249-1276061 (Clockwise)

Preceding gene: 146338294

Following gene: 146338296

Centisome position: 17.1

GC content: 64.08

Gene sequence:

>813_bases
TTGTCAGGAGCCATCACCGCGTTGAAATGGCTCCTGATTGTCCTGGTGGCGATCTACGCCACCGTGATCGCGGTGCTGTT
CGTGCGTCAGCGCGCGATGCTGTTTCCGATCCCGCCGGTCGGCCGCACCGCGCCCGCGGCCGCCGGTTTTCAGCAAGCTG
AAGAGCATGTGCTGACCTCCGCCGATGGCGAGAAGGTCATCGCCTGGCACGTGCCGCCGCAGCCCGGCCGCAAGGTGGTG
CTGTATTTCCCGGGTAATGGCGACTTCCTCGCAGGCGTCGTGTCGCGCTTCAAGGCGCTCACATCCGACGGCACCGGCCT
CGTCGCACTGTCCTATCGCGGCTATGCGGGCTCCACCGGCAGTCCGAGCGAGACGGGGCTGCTTCAGGATGCCGCAGCCG
CCTACGCTTTCACGCGCGACCGCTATGAGCCACAACGCATCGTCGTCTGGGGCTTCTCTCTGGGCAGCGGTGTGGCCACG
GCAATCGCCGCGGAGCATCCGATCGACAGGCTCATCCTCGAGGCGCCCTACACGTCCACCGTCGATGTCGCGTCCGACAT
GCTGAAGGTGGTTCCGGTCAGTCTGCTGATGCGCGACCGCTTCCACTCCGATCAGCGCATCGCCAAGGTCCACGTGCCGT
TGTTGATCATGCACGGCGCCAAGGATCCGGGGATTTCGATCCGCTTCGGGGAACGATTGTTCGCGCTTGCGCATGACCCC
AAGCGCTTCGTACGGTTTCCCGACGGCGGTCACAACGATCTGGATCTTTTTGGTGCGACAGACACTGCCAAAGGTTTCAT
CAACGCCCCCTAG

Upstream 100 bases:

>100_bases
CGGCATCGACAATCCGCTGTTCTACCGCGACAACACGATGATGCTGCTCGGCGACGCCAAGAAGATGACCGAGAATATCG
TGAAGGGCATGTAACCCGTC

Downstream 100 bases:

>100_bases
CTTTTTCCGCGTGAGCTGGCCTGCGCCGCTTCTCGCCGTGCTTCTCTCTGCAGCTCTGCCGATTCAGGCGCACGCCGCCG
AGCTGAACGGCGCCGCAATG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MSGAITALKWLLIVLVAIYATVIAVLFVRQRAMLFPIPPVGRTAPAAAGFQQAEEHVLTSADGEKVIAWHVPPQPGRKVV
LYFPGNGDFLAGVVSRFKALTSDGTGLVALSYRGYAGSTGSPSETGLLQDAAAAYAFTRDRYEPQRIVVWGFSLGSGVAT
AIAAEHPIDRLILEAPYTSTVDVASDMLKVVPVSLLMRDRFHSDQRIAKVHVPLLIMHGAKDPGISIRFGERLFALAHDP
KRFVRFPDGGHNDLDLFGATDTAKGFINAP

Sequences:

>Translated_270_residues
MSGAITALKWLLIVLVAIYATVIAVLFVRQRAMLFPIPPVGRTAPAAAGFQQAEEHVLTSADGEKVIAWHVPPQPGRKVV
LYFPGNGDFLAGVVSRFKALTSDGTGLVALSYRGYAGSTGSPSETGLLQDAAAAYAFTRDRYEPQRIVVWGFSLGSGVAT
AIAAEHPIDRLILEAPYTSTVDVASDMLKVVPVSLLMRDRFHSDQRIAKVHVPLLIMHGAKDPGISIRFGERLFALAHDP
KRFVRFPDGGHNDLDLFGATDTAKGFINAP
>Mature_269_residues
SGAITALKWLLIVLVAIYATVIAVLFVRQRAMLFPIPPVGRTAPAAAGFQQAEEHVLTSADGEKVIAWHVPPQPGRKVVL
YFPGNGDFLAGVVSRFKALTSDGTGLVALSYRGYAGSTGSPSETGLLQDAAAAYAFTRDRYEPQRIVVWGFSLGSGVATA
IAAEHPIDRLILEAPYTSTVDVASDMLKVVPVSLLMRDRFHSDQRIAKVHVPLLIMHGAKDPGISIRFGERLFALAHDPK
RFVRFPDGGHNDLDLFGATDTAKGFINAP

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To S.pombe bem46 and yeast YNL320w [H]

Homologues:

Organism=Homo sapiens, GI32528310, Length=230, Percent_Identity=29.5652173913043, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI32451492, Length=230, Percent_Identity=29.5652173913043, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI109689718, Length=287, Percent_Identity=26.4808362369338, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI24308097, Length=287, Percent_Identity=26.4808362369338, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI71051602, Length=210, Percent_Identity=30, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI71051600, Length=210, Percent_Identity=30, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI194306564, Length=222, Percent_Identity=29.7297297297297, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI49355781, Length=205, Percent_Identity=30.2439024390244, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI194306562, Length=185, Percent_Identity=29.7297297297297, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI151301175, Length=197, Percent_Identity=29.4416243654822, Blast_Score=75, Evalue=6e-14,
Organism=Escherichia coli, GI226510965, Length=213, Percent_Identity=29.5774647887324, Blast_Score=91, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17566318, Length=176, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71988362, Length=158, Percent_Identity=26.5822784810127, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324009, Length=254, Percent_Identity=27.1653543307087, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17137566, Length=262, Percent_Identity=27.4809160305344, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24655467, Length=214, Percent_Identity=30.8411214953271, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281362521, Length=211, Percent_Identity=28.436018957346, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281362519, Length=211, Percent_Identity=28.436018957346, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28571878, Length=211, Percent_Identity=28.436018957346, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24655464, Length=214, Percent_Identity=30.8411214953271, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002925 [H]

Pfam domain/function: PF01738 DLH [H]

EC number: NA

Molecular weight: Translated: 29047; Mature: 28916

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGAITALKWLLIVLVAIYATVIAVLFVRQRAMLFPIPPVGRTAPAAAGFQQAEEHVLTS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHCC
ADGEKVIAWHVPPQPGRKVVLYFPGNGDFLAGVVSRFKALTSDGTGLVALSYRGYAGSTG
CCCCEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCC
SPSETGLLQDAAAAYAFTRDRYEPQRIVVWGFSLGSGVATAIAAEHPIDRLILEAPYTST
CCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHCCHHHHEEECCCCCH
VDVASDMLKVVPVSLLMRDRFHSDQRIAKVHVPLLIMHGAKDPGISIRFGERLFALAHDP
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECEEEEEECCCCCCEEEEECCEEEEEECCH
KRFVRFPDGGHNDLDLFGATDTAKGFINAP
HHEEECCCCCCCCEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
SGAITALKWLLIVLVAIYATVIAVLFVRQRAMLFPIPPVGRTAPAAAGFQQAEEHVLTS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHCC
ADGEKVIAWHVPPQPGRKVVLYFPGNGDFLAGVVSRFKALTSDGTGLVALSYRGYAGSTG
CCCCEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCC
SPSETGLLQDAAAAYAFTRDRYEPQRIVVWGFSLGSGVATAIAAEHPIDRLILEAPYTST
CCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHCCHHHHEEECCCCCH
VDVASDMLKVVPVSLLMRDRFHSDQRIAKVHVPLLIMHGAKDPGISIRFGERLFALAHDP
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECEEEEEECCCCCCEEEEECCEEEEEECCH
KRFVRFPDGGHNDLDLFGATDTAKGFINAP
HHEEECCCCCCCCEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]