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The map label for this gene is cbbA [H]

Identifier: 146338221

GI number: 146338221

Start: 1195647

End: 1196714

Strand: Reverse

Name: cbbA [H]

Synonym: BRADO1120

Alternate gene names: 146338221

Gene position: 1196714-1195647 (Counterclockwise)

Preceding gene: 146338222

Following gene: 146338220

Centisome position: 16.05

GC content: 64.04

Gene sequence:

>1068_bases
ATGGCCCGCATTACCTTGCGTCAATTGCTCGATCACGCGGCGGAGCACGATTACGGCGTCCCGGCCTTCAACATCAACAA
CATGGAGCAGGCGCTGTCGATCATGGAGGCGGCGAGCTCCGCTGACGCCCCGGTGATCATCCAGGCCTCGCGCGGCGCCC
GCGCCTACGCCAACGACATCATGCTCAAGCACATGATGGACGCGCTGACCGAGATCTATCCGCAGATCCCGATCTGCGTG
CATCTCGACCACGGCAACGGCGCCGACACCTGCATGACCGCGATCCAGTCCGGCTTCACCTCGGTGATGATGGACGGCTC
GCTCAAGGCCGACGGCAAGACCCCGGCCGACTGGGACTACAATGTCGGCGTCACCAAGACGGTCGCCACCATGGCACATC
TCGGCGGCATCTCGGTCGAGGGCGAGCTCGGCGTGCTCGGCTCGCTCGAGACCGGCATGGGCGACAAGGAGGACGGCCAC
GGCGCCGAGGGCAAGCTGTCGCACGACCAGCTGCTGACCAATCCCGACGAGGCCGTGAAGTTCGTCCAGGAGACCAAGGT
CGACGCGCTGGCGATCGCGATGGGCACCTCGCACGGCGCCTACAAATTCACCCGCAAGCCGGATGGCGACATCCTTGCAA
TGAACGTGATCGAGGAGATCCACCGCAAGCTGCCGAACACGCATCTGGTGATGCACGGCTCCTCGTCGGTGCCGCAGGAC
CTGCAGGAGATCATCAATTCGTTCGGCGGCAAGATGAAGCCGACCTGGGGCGTGCCGGTCGCCGAGATCCAGCGCGGCAT
CAAGCACGGCGTGCGCAAGATCAATATCGACACCGACAACCGCATGGCGATGACCGGCCAGATCCGCAAGGTGCTGTCGC
AGCACCCGGAGGAGTTCGATCCGCGCAAATATTTGAAGCCGGCGATGGAAGCCATGACCAAGCTCTGCAAGCAGCGCTTC
GAGGAGTTCAACACTGCGGGCCAGGCCGGCAAGATCAAGCGCGTGCTGACAACCGCCGAGATGGCCAAGCGCTACGCCAA
GGGCGAGCTCGACCCGAAGGTGGCGTGA

Upstream 100 bases:

>100_bases
CCCTTGGATTCCGCCGGTCACCGCGTTATGCACGGTGCAGCAGTTTCGACGCGTGCGTCAGCCGCCGCACGGTCCAAATC
ATCATCAGGGAGTTCCAGCC

Downstream 100 bases:

>100_bases
GCTGGCCTGCAATCAGCTCTCTGGACCTCAGTGACCGCCAAGACCCCGGTCAGCTCCGCTCGCCCTTGCGGCAGGGCTAT
CGCATATGAAGATCGCGGTT

Product: fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase; Fructose-bisphosphate aldolase II [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MARITLRQLLDHAAEHDYGVPAFNINNMEQALSIMEAASSADAPVIIQASRGARAYANDIMLKHMMDALTEIYPQIPICV
HLDHGNGADTCMTAIQSGFTSVMMDGSLKADGKTPADWDYNVGVTKTVATMAHLGGISVEGELGVLGSLETGMGDKEDGH
GAEGKLSHDQLLTNPDEAVKFVQETKVDALAIAMGTSHGAYKFTRKPDGDILAMNVIEEIHRKLPNTHLVMHGSSSVPQD
LQEIINSFGGKMKPTWGVPVAEIQRGIKHGVRKINIDTDNRMAMTGQIRKVLSQHPEEFDPRKYLKPAMEAMTKLCKQRF
EEFNTAGQAGKIKRVLTTAEMAKRYAKGELDPKVA

Sequences:

>Translated_355_residues
MARITLRQLLDHAAEHDYGVPAFNINNMEQALSIMEAASSADAPVIIQASRGARAYANDIMLKHMMDALTEIYPQIPICV
HLDHGNGADTCMTAIQSGFTSVMMDGSLKADGKTPADWDYNVGVTKTVATMAHLGGISVEGELGVLGSLETGMGDKEDGH
GAEGKLSHDQLLTNPDEAVKFVQETKVDALAIAMGTSHGAYKFTRKPDGDILAMNVIEEIHRKLPNTHLVMHGSSSVPQD
LQEIINSFGGKMKPTWGVPVAEIQRGIKHGVRKINIDTDNRMAMTGQIRKVLSQHPEEFDPRKYLKPAMEAMTKLCKQRF
EEFNTAGQAGKIKRVLTTAEMAKRYAKGELDPKVA
>Mature_354_residues
ARITLRQLLDHAAEHDYGVPAFNINNMEQALSIMEAASSADAPVIIQASRGARAYANDIMLKHMMDALTEIYPQIPICVH
LDHGNGADTCMTAIQSGFTSVMMDGSLKADGKTPADWDYNVGVTKTVATMAHLGGISVEGELGVLGSLETGMGDKEDGHG
AEGKLSHDQLLTNPDEAVKFVQETKVDALAIAMGTSHGAYKFTRKPDGDILAMNVIEEIHRKLPNTHLVMHGSSSVPQDL
QEIINSFGGKMKPTWGVPVAEIQRGIKHGVRKINIDTDNRMAMTGQIRKVLSQHPEEFDPRKYLKPAMEAMTKLCKQRFE
EFNTAGQAGKIKRVLTTAEMAKRYAKGELDPKVA

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=342, Percent_Identity=32.7485380116959, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI87082041, Length=329, Percent_Identity=32.2188449848024, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1788072, Length=274, Percent_Identity=29.1970802919708, Blast_Score=101, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006412
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 38706; Mature: 38575

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00602 ALDOLASE_CLASS_II_1 ; PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARITLRQLLDHAAEHDYGVPAFNINNMEQALSIMEAASSADAPVIIQASRGARAYANDI
CCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHH
MLKHMMDALTEIYPQIPICVHLDHGNGADTCMTAIQSGFTSVMMDGSLKADGKTPADWDY
HHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCHHHEEECCCCCCCCCCCCCCCC
NVGVTKTVATMAHLGGISVEGELGVLGSLETGMGDKEDGHGAEGKLSHDQLLTNPDEAVK
CCCHHHHHHHHHHHCCCCCCCCCCCEECHHCCCCCCCCCCCCCCCCCHHHHCCCHHHHHH
FVQETKVDALAIAMGTSHGAYKFTRKPDGDILAMNVIEEIHRKLPNTHLVMHGSSSVPQD
HHHHHCHHEEEEEECCCCCCEEECCCCCCCEEHHHHHHHHHHHCCCCEEEEECCCCCHHH
LQEIINSFGGKMKPTWGVPVAEIQRGIKHGVRKINIDTDNRMAMTGQIRKVLSQHPEEFD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCEEHHHHHHHHHHHCCCCCC
PRKYLKPAMEAMTKLCKQRFEEFNTAGQAGKIKRVLTTAEMAKRYAKGELDPKVA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ARITLRQLLDHAAEHDYGVPAFNINNMEQALSIMEAASSADAPVIIQASRGARAYANDI
CCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHH
MLKHMMDALTEIYPQIPICVHLDHGNGADTCMTAIQSGFTSVMMDGSLKADGKTPADWDY
HHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCHHHEEECCCCCCCCCCCCCCCC
NVGVTKTVATMAHLGGISVEGELGVLGSLETGMGDKEDGHGAEGKLSHDQLLTNPDEAVK
CCCHHHHHHHHHHHCCCCCCCCCCCEECHHCCCCCCCCCCCCCCCCCHHHHCCCHHHHHH
FVQETKVDALAIAMGTSHGAYKFTRKPDGDILAMNVIEEIHRKLPNTHLVMHGSSSVPQD
HHHHHCHHEEEEEECCCCCCEEECCCCCCCEEHHHHHHHHHHHCCCCEEEEECCCCCHHH
LQEIINSFGGKMKPTWGVPVAEIQRGIKHGVRKINIDTDNRMAMTGQIRKVLSQHPEEFD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCEEHHHHHHHHHHHCCCCCC
PRKYLKPAMEAMTKLCKQRFEEFNTAGQAGKIKRVLTTAEMAKRYAKGELDPKVA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1939098 [H]